Abstract
Crushing of the sciatic nerve in new-born rats leads subsequently to a permanent decrease in the number and size of both sensory and motor nerve fibers. The number of motor axons and muscle fibers in the soleus is decreased by more than a half; the mean diameter of motor axons is reduced by 25 %, but that of muscle fibers is increased by 20 %. The number of encapsulated muscle receptors is dramatically reduced in the soleus (SOL), tibialis anterior (TA) and extensor digitorum longus (EDL) after neonatal nerve crush (Zelená and Hník, 1963). This is in contrast to the peripheral nerve regeneration following nerve crush in adult animals. The recovery of muscle weight after neonatal nerve crush was also found to be rather poor as compared with the result of muscle reinnervation in adult animals.
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References
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© 1988 Springer Science+Business Media New York
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Hník, P., Vejsada, R., Navarrete, R., Paleček, J., Payne, R., Borecka, U. (1988). Late Effects of Early Hind-Limb Denervation and Reinnervation in Rats: An EMG Study. In: Hník, P., Soukup, T., Vejsada, R., Zelená, J. (eds) Mechanoreceptors. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0812-4_28
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DOI: https://doi.org/10.1007/978-1-4899-0812-4_28
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