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Poly(Ethylene Glycol) Chemistry pp 303–324Cite as

Immobilization of Proteins via PEG Chains

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Part of the book series: Topics in Applied Chemistry ((TAPP))

Abstract

Grafting of poly(ethylene glycol) (or PEG) to solid surfaces has been recognized as a technique for obtaining low protein adsorption and low cell adhesion characteristics.1,2 For instance, PEG coating is reported to give a marked suppression of plasma protein adsorption and platelet adhesion leading to reduced risk of thrombus formation, as demonstrated both in vitro and in vivo.3–5

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Author information

Author notes

  1. Krister Holmberg

    Present address: Institute for Surface Chemistry, S-11486, Stockholm, Sweden

  2. Maj-Britt Stark

    Present address: Astra Hässle AB, Kärragatan 5, S-43183, Mölndal, Sweden

Authors and Affiliations

  1. Berol Nobel, S-44485, Stenungsund, Sweden

    Krister Holmberg & Karin Bergström

  2. Department of Histology, University of Göteborg, S-40033, Göteborg, Sweden

    Maj-Britt Stark

Authors
  1. Krister Holmberg
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  2. Karin Bergström
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  3. Maj-Britt Stark
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Editor information

Editors and Affiliations

  1. Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama, 35899, USA

    J. Milton Harris

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© 1992 Springer Science+Business Media New York

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Holmberg, K., Bergström, K., Stark, MB. (1992). Immobilization of Proteins via PEG Chains. In: Harris, J.M. (eds) Poly(Ethylene Glycol) Chemistry. Topics in Applied Chemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0703-5_19

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  • DOI: https://doi.org/10.1007/978-1-4899-0703-5_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0705-9

  • Online ISBN: 978-1-4899-0703-5

  • eBook Packages: Springer Book Archive

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