Abstract
Fescue alkaloid intake by cattle results in adverse metabolic effects that cause billion dollar losses annually to livestock production in the U.S. alone (Bacon et al., 1977; Garner and Cornell, 1978; Bush et al., 1979; Hoveland et al., 1980; Hemken, et al., 1981; Robbins, 1983; Wallner et al., 1983; Ball, 1984; Jackson et al., 1984ab; Stuedemann et al., 1985; Fribourg et al., 1991, 1995; Hoveland, 1991, 1993; Cross et al., 1995; Porter and Thompson, 1992; Strickland et al., 1993; Paterson et al., 1995), with the fescue toxicosis syndrome described as the major grass-induced toxicosis in the country (Cheeke, 1995). These estimates do not reflect losses attributable to the same alkaloids found in ergotized grains and grasses (Bacon et al., 1986, 1995; Coppock et al., 1989). Grasslands make up an increasing part of the world-wide ecosystem (Clay, 1991, 1993aĆ³, 1994; Siegel and Bush, 1994; Hume, 1993), and endophytic fungi correspondingly infect a larger proportion of the grasslands each year. The presence of the endophyte of tall fescue in several countries gives the fescue toxicosis problem global significance (Siegel et al., 1984; Latch et al., 1984, 1987; Fletcher et al., 1990, 1993). For additional perspectives of important endophyte-infected forage relationships to animals, several reviews can be consulted (Read and Camp, 1986; Bacon, 1993, 1995; Buckner et al., 1979; Stuedemann and Hove-land, 1988; Porter and Thompson, 1992; Strickland et al., 1993; Thompson and Stuedemann 1993; Stuedemann and Thompson, 1993; Schmidt and Osborn, 1993; Prestidge, 1993; Thompson and Garner, 1994; Spiers et al., 1995b; Paterson et al., 1995; Porter, 1994, 1995; Cheeke, 1995; Joost, 1995, Cross et al., 1995).
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Oliver, J.W. (1997). Physiological Manifestations of Endophyte Toxicosis in Ruminant and Laboratory Species. In: Bacon, C.W., Hill, N.S. (eds) Neotyphodium/Grass Interactions. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0271-9_56
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