Abstract
Liposome bilayers have been attractive tools mainly as models of biological membranes and as delivery devices. Almost immediately after being widely accepted as membrane mimicking models, numerous studies appeared which used liposomes as carrier vehicles of other molecules (Gregoriadis, 1988). Due to their ability to act as “solvents” for both lipophilic (lipid bilayer phase) and hydrophilic (inner aqueous phase) molecules, liposomes have been used to deliver enzymes, genetic material, anticancer drugs (eg. doxorubicin), agents for diagnostic imaging and antibacterials, to name only a few. Liposomes have also proved particularly useful as general vaccine adjuvants (for example, there is already a liposome-based vaccine against hepatitis A), surfactant providers for newborn babies suffering from lung surfactant deficiency, and in the formulation of cosmetics as evidenced by the plethora of commercial cosmetic products claiming to contain liposomes.
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Kostarelos, K. (1998). Engineering Stealth™ Liposome Surfaces: Exercises in Colloid Chemistry Principles. In: Gregoriadis, G., McCormack, B. (eds) Targeting of Drugs 6. NATO ASI Series, vol 300. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0127-9_14
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DOI: https://doi.org/10.1007/978-1-4899-0127-9_14
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