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Arenaviruses

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Viral Infections of Humans

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Abstract

Arenavirus is the designation for members of the family Arenaviridae.(61) Virions are round to ovoid pleomorphic particles usually 90–300 nm in diameter. They have an electron-dense membrane with spikes or projections and a variable number of dense inclusions that convey a sense that virions are sprinkled with sand (arenosus). Arenaviruses have a negative-stranded, bipartite RNA genome and are antigenically related. Lymphocytic choriomeningitis (LCM) virus, the first recognized member, is considered the prototype arenavirus. These viruses are important public health problems in geographically restricted regions of tropical Africa and South America. While exotic to North America, these viruses have the potential to be introduced via these and other international crossroads by travelers returning from the tropical foci where the viruses are endemic.

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    Peter B. Jahrling

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    Alfred S. Evans

  2. Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 35294-0008, Birmingham, Alabama, USA

    Richard A. Kaslow

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Jahrling, P.B. (1997). Arenaviruses. In: Evans, A.S., Kaslow, R.A. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0036-4_7

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