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Viral Infections of Humans pp 983–1023Cite as

Human Papillomaviruses

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Abstract

The papillomaviruses are small, double-stranded DNA viruses that infect epithelia, causing a variety of lesions including warts, intraepithelial neoplasia, and carcinoma.(227) Species-specific papillomaviruses infect many kinds of animals, including mammals and birds.(142,246)

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References

  1. Alloue, M. I., Barr, B. B. B., Mclaren, K. M., Smith, I. W., Bunney, M. H., And Smart, G. E., Human papillomavirus infection and cervical intraepithelial neoplasia in women with renal allografts, Br. Med. J. 298: 153–156 (1989).

    Article  Google Scholar 

  2. Andersson-Ellstrom, A., Dillner, J., Hagmar, B., Schiller, J., And Forssman, L., No serological evidence for nonsexual spread of Hpv16, Lancet 344: 1435 (1994).

    Google Scholar 

  3. Anwar, K., Phil, M., Naiki, H., Nakakuki, K., And Inuzuka, M., High frequency of human papillomavirus infection in carcinoma of the urinary bladder, Cancer 70: 1967–1973 (1992).

    Article  PubMed  CAS  Google Scholar 

  4. Apple, R. J., Erlich, H. A., Klitz, W., Manos, M. M., Becker, T. M., And Wheeler, C. M., Hla DR-DQ associations with cervical carcinoma show papillomavirus-type specificity, Nat. Genet. 6: 157–162 (1994).

    Article  PubMed  CAS  Google Scholar 

  5. Aynaud, O., Ionesco, M., And Barrasso, R., Penile intraepithelial neoplasia. Specific clinical features correlate with histologic and virologic findings, Cancer 74: 1762–1767 (1994).

    Article  PubMed  CAS  Google Scholar 

  6. Baird, P. J., Serological evidence for the association of pa- pillomavirus and cervical neoplasia, Lancet 2: 17–18 (1983).

    Article  PubMed  CAS  Google Scholar 

  7. Barrasso, R., Hpv-related genital lesions in men, in: The Epidemiology of Human Papillomavirus and Cervical Cancer (N. Munoz, F. X. Bosch, K. V. Shah, And A. Meheus, Eds.), pp. 85–92, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  8. Barrasso, R., DE Brux, J., Croissant, O., And Orth, G., High prevalence of papillomavirus-associated penile intraepithelial neoplasia in sexual partners of women with cervical intraepithelial neoplasia, N. Engl. J. Med. 317: 916–923 (1987).

    Article  PubMed  CAS  Google Scholar 

  9. Barrett, T. J., Silbar, J. D., And Mcginley, J. P., Genital warts-a venereal disease, J.A.M.A. 154: 333–334 (1954).

    Article  CAS  Google Scholar 

  10. Bauer, H. M., Hildesheim, A., Schiffman, M. H., Glass, A. G., Rush, B. B., ScoTT, D. R., Cadell, D. M., Kurman, R. J., And Manos, M. M., Determinants of genital human papillomavirus infection in low-risk women in Portland, Oregon, Sex. Transm. Dis. 20: 274–278 (1993).

    Article  PubMed  CAS  Google Scholar 

  11. Bauer, H. M., Ting, Y., Greer, C. E., Chambers, J. C., Tashiro, C. J., Chimera, J., Reingold, A., And Manos, M. M., Genital human papillomavirus infection in female university students as determined by a Pcr-based method, J.A.M.A. 265: 472477 (1991).

    Google Scholar 

  12. Bergeron, C., Barrasso, R., Beaudenon, S., Flamant, P., Croissant, O., And Orth, G., Human papillomaviruses associated with cervical intraepithelial neoplasia. Great diversity and distinct distribution in low-and high-grade lesions, Am. J. Surg. Pathol. 16: 641–649 (1992).

    Article  CAS  Google Scholar 

  13. Bergman, A., And Nalick, R., Prevalence of human papillomavirus infection in men: Comparison of the partners of infected and uninfected women, J. Reprod. Med. 37: 710–712 (1992).

    PubMed  CAS  Google Scholar 

  14. Bernard, H. U., Chan, S. Y., Manos, M. M., Ong, C. K., Villa, L. L., Delius, H., Peyton, C. L., Bauer, H. M., And Wheeler, C. M., Identification and assessment of known and novel human papillomaviruses by polymerase chain reaction amplification, restriction fragment length polymorphisms, nucleotide sequence, and phylogenetic algorithms, J. Infect. Dis. 170: 1077–1085 (1994).

    Article  PubMed  CAS  Google Scholar 

  15. Bernstein, S. G., Voet, R. L., Guzick, D. S., Melancon, J. T., Ronan-Cowen, L., Lifshitz, S., And Buchsbaum, H. J., Prevalence of papillomavirus infection in colposcopically directed cervical biopsy specimens in 1972 and 1982, Am. J. Obstet. Gynecol. 151: 577–581 (1985).

    PubMed  CAS  Google Scholar 

  16. Boring, C. C., Squires, T. S., Tong, T., And Montgomery, S., Cancer statistics, 1994, CA Cancer J. Clin. 44: 7–26 (1995).

    Article  Google Scholar 

  17. Bosch, F X., Manos, M. M., Munoz, N., Sherman, M. E., Jansen, A., Pet°, J., Schiffman, M. H., Moreno, V., Shah, K. V., And The Ibscc Study Group, Prevalence of Hpv Dna in cervical cancer in 22 countries, J. Natl. Cancer Inst. 87: 796–802 (1995).

    Article  PubMed  CAS  Google Scholar 

  18. Bosch, F. X., Munoz, N., DE Sanjose, S., Izarzugaza, I., Gill, M., Viladiu, P., Tormo, M. J., Moreo, P, Ascunce, N., Gonzalez, L C., Tafur, L., Kaldor, J. M., Guerrero, E., Aristizabal, N., Santamaria, M., Alonso DE Ruiz, P., And Shah, K., Risk factors for cervical cancer in Columbia and Spain, Int. J. Cancer 52: 750–758 (1992).

    Article  PubMed  CAS  Google Scholar 

  19. Brandsma, J., Burk, R. D., Lancaster, W. D., Pfister, H., And Schiffman, M. H., Inter-laboratory variation as an explanation for varying prevalence estimates of human papillomavirus infection, Int. J. Cancer 43: 260–262 (1989).

    Article  PubMed  CAS  Google Scholar 

  20. Brandsma, J L, Animal models for Hpv vaccine development, Papillomavirus Rep. 5: 105–111 (1994).

    Google Scholar 

  21. Brinton, L. A., Li, J. Y., Shod-DE, R., Huang, S., Sheng, X. B., Bai-Gao, S., Zhe-Jun, Z. S., Schiffman, M. H., And Dawsey, S., Risk factors for penile cancer: Results from a case-control study in China, Int. J. Cancer 47: 504–509 (1991).

    Article  PubMed  CAS  Google Scholar 

  22. Brinton, L. A., Nasca, P. C., Mallin, K., Baptiste, M. S., Wilbanks, G. D., And Richart, R. M., Case-control study of cancer of the vulva, Obstet. Gynecol. 75: 859–866 (1990).

    PubMed  CAS  Google Scholar 

  23. Brinton, L. A., Nasca, P. C., Mallin, K., Schairer, C., Rosenthal, J., Rothenberg, R., Yordan, E., And Richart, R., Case-control study of in situ and invasive carcinoma of the vagina, Gynecol. Oncol. 38: 49–54 (1990).

    Article  PubMed  CAS  Google Scholar 

  24. Brown, D. R., Bryan, J. T., Cramer, H., And Fife, K. H.; Analysis of human papillomavirus types in exophytic condylomata acuminata by hybrid capture and Southern blot techniques, J. Clin. Microbiol. 31: 2667–2673 (1993).

    PubMed  CAS  Google Scholar 

  25. Burger, M. P.M., Hollema, H., Gouw, A. S. H., Peiters, W. J. L. M., And Quint, W. G. V., Cigarette smoking and human papillomavirus in patients with reported cervical cytological abnormality, BE Med. J. 306: 749–752 (1993).

    Article  CAS  Google Scholar 

  26. Burk, R. D., Kadish, A. S., Calderin, S., And Romney, S. L., Human papillomavirus infection of the cervix detected by cervicovaginal lavage and molecular hybridization: Correlation with biopsy results and Papanicolaou smear, Am. J. Obstet. Gynecol. 154: 982–989 (1986).

    PubMed  CAS  Google Scholar 

  27. Burns, D. A., Warts and all-the history and folklore of warts: A review, J. R. Soc. Med. 85: 37–40 (1992).

    PubMed  CAS  Google Scholar 

  28. Buscema, J., Shah, K., Hsu, S., Rosenshein, N., And Woodruff, J. D., Genetic investigation of the cellular origin of vulvovaginal condylomata acuminata, Cancer Cells 5: 245–247 (1987).

    Google Scholar 

  29. Butterworth, C. E., Hatch, K. D., Macaluso, M., Cole, P., Sauberlich, H. E., Soong, S. J., Borst, M., And Baker, V. V, Folate deficiency and cervical dysplasia, J.A.M.A. 267: 528–533 (1992).

    Article  PubMed  Google Scholar 

  30. Byrne, J. C., Tsao, M. S., Fraser, R. S., And Howley, P. M., Human papillomavirus-11 Dna in a patient with chronic laryngotracheobronchial papillomatosis and metastatic squamous-cell carcinoma of the lung, N. Engl. J. Med. 317: 873–878 (1987).

    Article  PubMed  CAS  Google Scholar 

  31. Campion, M. J., Mccance, D. J., Singer, A., And Cuzick, J., Progressive potential of mild cervical atypia: Prospective cytological, colposcopic, and virological study, Lancet 2: 237–240 (1986).

    Article  PubMed  CAS  Google Scholar 

  32. Campo, M. S., Cell transformation by animal papillomaviruses, J. Gen. Virol. 73: 217–222 (1992).

    Article  PubMed  CAS  Google Scholar 

  33. Campo, M. S., Grindlay, G. J., O’Neil, B. W., Chandrachud, L. M., Mcgarvie, G. M., And Jarrett, W. F. H., Prophylactic and therapeutic vaccination against a mucosal papillomavirus, J. Gen. Virol. 74: 945–953 (1993).

    Article  PubMed  CAS  Google Scholar 

  34. Carter, J. J., Hagensee, M., Taflin, M. C., Lee, S. K., KoUtsky, L. A., And Galloway, D. A., Hpv-1 capsids expressed in vitro detect human serum antibodies associated with foot warts, Virology 195: 456–462 (1993).

    CAS  Google Scholar 

  35. Carter, J. J., Hagensee, M. B., Lee, S. K., Mcknight, B., Koutsky, L. A., And Galloway, D. A., Use of Hpv 1 capsids produced by recombinant vaccinia viruses in an Elisa to detect serum antibodies in people with foot warts, Virology 199(2):284291 (1994).

    Google Scholar 

  36. Cason, J., Kaye, J. N., And Best, J. M., Non-sexual acquisition of human genital papillomaviruses, Papillomavirus Rep. 6: 1–7 (1995).

    Google Scholar 

  37. Centers For Disease Control, Condyloma acuminatumUnited States: 1966–1981, Morbid. Mortal. Week. Rep. 32: 306308 (1983).

    Google Scholar 

  38. Chan, K. W., Lam, K. Y., Chan, A. C. L., Lau, R, And Srivastava, G., Prevalence of human papillomavirus types 16 and 18 in penile carcinoma: A study of 41 cases using Pcr, J. Clin. Pathol. 47 (9): 823–826 (1994).

    Article  PubMed  CAS  Google Scholar 

  39. Chan, S. Y., Bernard, H. U., Ong, C. K., Chan, S. P., Hofmann, B., And Delius, H., Phytogenetic analysis of 48 papillomavirus types and 28 subtypes and variants: A showcase for the molecular evolution of Dna viruses, J. Virol. 66: 57145725 (1992).

    Google Scholar 

  40. Chan, S. Y., Ho, L., Ong, C. K., Chow, V., Drescher, B., Durst, M., Ter Meulen, J., Villa, L., Luande, J., Mgaya, H. N., And Bernard, H. U., Molecular variants of human papillomavirus type 16 from four continents suggest ancient pandemic spread of the virus and its coevolution with humankind, J. Virol. 66 (4): 2057–2066 (1992).

    PubMed  CAS  Google Scholar 

  41. Chang, F., Syrjanen, S., Kellokoski, J., And Syrjanen, K., Human papillomavirus (Hpv) infections and their associations with oral disease, J. Oral Pathol. Med. 20: 305–317 (1991).

    Article  PubMed  CAS  Google Scholar 

  42. Chang, F., Syrjanen, S., Shen, Q., Hongxiu, J., And Syrjanen, K., Human papillomavirus (Hpv) Dna in esophageal precancer lesion and squamous cell carcinoma from China, Int. J. Cancer 45: 21–25 (1990).

    Article  PubMed  CAS  Google Scholar 

  43. Chang, F., Syrjanen, S., Wang, L., And Syrjanen, K., Infectious agents in the etiology of esophageal cancer, Gastroenterology 103: 1336–1348 (1992).

    PubMed  CAS  Google Scholar 

  44. Childers, J. M., Chu, J., Voigt, L. F., Feigl, P., Tamimi, H. K., Franklin, E. W., Alberts, D. S., And Meyskens, F. L., JR., Chemoprevention of cervical cancer with folic acid: A phase Iii Southwest Oncology Group intergroup study, Cancer Epidemiol. Biomarkers Prey. 4: 155–159 (1995).

    CAS  Google Scholar 

  45. Chung, G. T., Huang, D. R, Lo, K. W., Chan, M. K., And Wong, F. W., Genetic lesions in the carcinogenesis of cervical cancer, Anticancer Res. 12: 1485–1490 (1992).

    PubMed  CAS  Google Scholar 

  46. Coggins, J. R., And Zur Hausen, H., Workshop on papillomaviruses and cancer, Cancer Res. 39: 545–546 (1979).

    Google Scholar 

  47. Couturier, J., Sastre, G. X., Schneider, M. S., Labib, A., And Orth, G., Integration of papillomavirus Dna near myc genes in genital carcinomas and its consequences for proto-oncogene expression, J. Virol. 65: 4534–4538 (1991).

    PubMed  CAS  Google Scholar 

  48. Cox, J. T., Lorincz, A. T., Schiffman, M. H., Sherman, M. E., Kurman, R. J., Hussein, M., And Cullen, A., Human papillomavirus testing by hybrid capture appears to be useful in triaging women with a cytologic diagnosis of atypical squamous cells of undetermined significance, Am. J. Obstet. Gynecol. 172: 946–954 (1995).

    Article  PubMed  CAS  Google Scholar 

  49. Cox, J. T., Schiffman, M. H., Winzelberg, A. J., And Patter-Son, J. M., An evaluation of Hpv testing as a part of referral to colposcopy clinic, Obstet. Gynecol. 80: 389–395 (1992).

    PubMed  CAS  Google Scholar 

  50. Crawford, L., Prospects for cervical cancer vaccines, Cancer Surv. 16: 215–229 (1993).

    PubMed  CAS  Google Scholar 

  51. Crum, C. R, Carcinoma of the vulva: Epidemiology and pathogenesis, Obstet. Gynecol. 49: 448–454 (1992).

    Article  Google Scholar 

  52. Cubie, H. A., Norval, M., Crawford, L., Banks, L., And Crook, T., Lymphoproliferative response to fusion proteins of human papillomaviruses in patients with cervical intraepithelial neoplasia, Epidemiol. Infect. 103: 625–632 (1994).

    Article  Google Scholar 

  53. Cullen, A. P., Reid, R., Campion, M., And Lorincz, A. T., Analysis of the physical state of different human papillomavirus Dnas in intraepithelial and invasive cervical neoplasia, J. Virol. 65: 606–612 (1991).

    PubMed  CAS  Google Scholar 

  54. Cuzick, J., Terry, G., Ho, L., Hollingworth, T., And Anderson, M., Human papillomavirus type 16 Dna in cervical smears as a predictor of high-grade cervical intraepithelial neoplasia, Lancet 339: 959–960 (1992).

    CAS  Google Scholar 

  55. DE Sanjose, S., Munoz, N., Bosch, F. X., Reimann, K., Pedersen, N. S., Orfila, J., Ascunce, N., Gonzalez, L. C., Tafur, L., Gill, M., Lette, I., Viladiu, P., Tormo, M. J., Moreo, P., Shah, K., And Wahren, B., Sexually transmitted agents and cervical neoplasia in Colombia and Spain, Int. J. Cancer 56: 358363 (1994).

    Google Scholar 

  56. DE Sanjose, S., Santamaria, M., Alonso DE Ruiz, P., Aristizabal, N., Guerrero, E., Castellsague, X., And Bosch, F. X., Hpv types in women with normal cervical cytology, in: The Epidemiology of Human Papillomavirus and Cervical Cancer (N. Munoz, F. X. Bosch, K. V. Shah And A. Meheus, Eds.), pp. 75–84, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  57. DE Villiers, E. M., Minireview: Heterogeneity of the human papillomavirus group, J. V irol. 63: 4898–4903 (1989).

    CAS  Google Scholar 

  58. DE Villiers, E. M., Papilloma viruses in cancers and papillomas of the aerodigestive tract, Biomed. Pharmacother. 43: 31–36 (1989).

    Article  PubMed  CAS  Google Scholar 

  59. DE Villiers, E. M., Human pathogenic papillomavirus types, in: Current Topics in Microbiology and Immunology, Vol. 186, Human Pathogenic Papillomaviruses (H. Zur Hausen, ED.), pp. 112, Springer-Verlag, Heidelberg, 1994.

    Google Scholar 

  60. DE Villiers, E. M., Wagner, D., Schneider, A., Wesch, H., Muni, F., Miklaw, H., And Zur Hausen, H., Human papillomavirus Dna in women without and with cytological abnormalities: Results of a 5-year follow-up study, Gynecol. Oncol. 44: 33–39 (1992).

    Article  PubMed  CAS  Google Scholar 

  61. Debritton, R. C., Hildesheim, A., Delao, S. L., Brinton, L. A., Sathya, P., And Reeves, W. C., Human papillomavirus and other influences on survival from cervical cancer in Panama, Obstet. Gynecol. 81: 19–24 (1993).

    PubMed  CAS  Google Scholar 

  62. Delius, H. J., Evolution of papillomaviruses, in: Human Pathogenic Papillomaviruses (H. Zur Hausen, ED.), pp. 13–31, Springer Verlag, Heidelberg, 1994.

    Google Scholar 

  63. Dillner, J., Dillner, L., Robb, J., Willems, J., Jones, I., Lancaster, W., Smith, R., And Lerner, R., A synthetic peptide defines a serologic IgA response to a human papillomavirus-encoded nuclear antigen expressed in virus-carrying cervical neoplasia, Proc. Natl. Acad. Sci. Usa 86: 3838–3841 (1989).

    Article  PubMed  CAS  Google Scholar 

  64. Dillner, J. Wiklund, F., Lenner, P., Eklund, C., Fredriksson-Shanazarian, V., Schiller, J. T., Hibma, M., Hall Mans, G., And Stendahl, U., Antibodies against linear and conformational epitopes of human papillomavirus type 16 that independently associate with incident cervical cancer, Int. J. Cancer 60:1–6 (1995).

    Google Scholar 

  65. Dillner, L., Bekassy, Z., Jonsson, N., Moreno-Lopez, J., And Blomberg, J., Detection of IgA antibodies against human papillomavirus in cervical secretions from patients with cervical intraepithelial neoplasia, Int. J. Cancer 43: 36–40 (1989).

    Article  PubMed  CAS  Google Scholar 

  66. Dilorenzo, T. P., Tamsen, A., Abramson, A. L., And Steinberg, B. M., Human papillomavirus type 6A Dna in the lung carcinoma of a patient with recurrent laryngeal papillomatosis is characterized by a partial duplication, J. Gen. Virol. 73(2):423428 (1992).

    Google Scholar 

  67. Duggan-Keen, M., Keating, P. J., Cromme, F. V., Wal-Boomers, J. M. M., And Stern, P. L., Alterations in major histocompatibility complex expression in cervical cancer: Possible consequences for immunotherapy, Papillomavirus Rep. 5: 3–9 (1994).

    Google Scholar 

  68. Durst, M., Gissmann, L., Ikenberg, H., And Zur Hausen, H., A papillomavirus Dna from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions, Proc. Natl. Acad. Sci. Usa 80: 3812–3815 (1983).

    Article  PubMed  CAS  Google Scholar 

  69. Dyson, N., Howley, P. M., Munger, K., And Harlow, E., The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product, Science 243: 934–937 (1989).

    Article  PubMed  CAS  Google Scholar 

  70. Editorial, Histopathological grading of cervical intraepithelial neoplasia (Cin)-is there a need for change?, J. Pathol. 159: 273–275 (1989).

    Article  Google Scholar 

  71. EL Awady, M. K., Kaplan, J. B., O’Brien, S. J., And Burk, R. D., Molecular analysis of integrated human papillomavirus 16 sequences in the cervical cancer cell line Siha, Virology 159: 389–398 (1987).

    Article  PubMed  CAS  Google Scholar 

  72. Eluf-Neto, J., Booth, M., Munoz, N., Bosch, F. X., Meijer, C. J., And Walboomers, J. M., Human papillomavirus and invasive cervical cancer in Brazil, Br. J. Cancer 69: 114–119 (1994).

    Article  Google Scholar 

  73. Evans, S., And Dowling, K., The changing prevalence of cervical human papilloma virus infection, Aust. NZ J. Obstet. Gynecol. 30 (4): 375–377 (1990).

    Article  CAS  Google Scholar 

  74. Fairley, C. K., Chen, S., Tabrizi, S. N., Leeton, K., Quinn, M. A., And Garland, S. M., The absence of genital human papillomavirus Dna in virginal women, Int. J. Std Aids 3: 414417 (1992).

    Google Scholar 

  75. Fairley, C. K., Chen, S., Tabrizi, S. N., Quinn, M. A., Mcneil, J. J., And Garland, S. M., Tampons: A novel patient-administered method for the assessment of genital human papillomavirus infection, J. Infect. Dis. 165: 1103–1106 (1992).

    Article  PubMed  CAS  Google Scholar 

  76. Fairley, C. K., Shell, A. G. R., Mcneil, J. J., UGom, A. M., Disney, A. P. S., Giles, G. G., And Amiss, N., The risk of anogenital malignancies in dialysis and transplant patients, Clin. Nephrol. 41 (2): 101–105 (1994).

    PubMed  CAS  Google Scholar 

  77. Farthing, A., Masterson, P., Mason, W. P., And Vousden, K. H., Human papillomavirus detection by hybrid capture and its possible clinical use, J. Clin. Pathol. 47: 649–652 (1994).

    Article  PubMed  CAS  Google Scholar 

  78. Ferenczy, A., Bergeron, C., And Richart, R. M., Human papillomavirus Dna in fomites on objects used for the management of patients with genital human papillomavirus infections, Obstet. Gynecol. 74: 950–954 (1989).

    PubMed  CAS  Google Scholar 

  79. Ferenczy, A., Bergeron, C., And Richart, R. M., Human papillomavirus Dna in CO2 laser-generated plume of smoke and its consequences to the surgeon, Obstet. Gynecol. 75: 114–118 (1990).

    PubMed  CAS  Google Scholar 

  80. Ferenczy, A., Mitao, M., Nagai, N., Silverstein, S. J., And Crum, C. P., Latent papillomavirus and recurring genital warts, N. Engl. J. Med. 313: 784–788 (1985).

    Article  PubMed  CAS  Google Scholar 

  81. Fisher, M., Rosenfeld, W. D., And Burk, R. D., Cervicovaginal human papillomavirus infection in suburban adolescents and young adults, J. Pediatr. 119: 821–825 (1991).

    Article  PubMed  CAS  Google Scholar 

  82. Franco, E. L., The sexually transmitted disease model for cervical cancer: Incoherent epidemiologic findings and the role of misclassification of human papillomavirus infection, Epidemiology 2: 98–106 (1991).

    Article  PubMed  CAS  Google Scholar 

  83. Frazer, I. H., Leonard, J. H., Schonrock, J., Wright, R. G., And Kearsley, J. H., Hpv Dna in oropharyngeal squamous cell cancers: Comparison of results from four Dna detection methods, Pathology 25: 138–143 (1993).

    Article  PubMed  CAS  Google Scholar 

  84. Fuchs, P. G., Girardi, E, And Pfister, H., Human papillomavirus Dna in normal, metaplastic, preneoplastic and neoplastic epithelia of the cervix uteri, Int. J. Cancer 41: 41–45 (1988).

    Article  PubMed  CAS  Google Scholar 

  85. Galloway, D., Serological assays for the detection of Hpv antibodies, in: The Epidemiology of Human Papillomavirus and Cervical Cancer (N. Munoz, E X. Bosch, K. V. Shah, And A. Meheus, Eds.), pp. 147–161, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  86. Garlick, J. A., Calderon, S., Buchner, A., And Mitranirosenbaum, S., Detection of human papillomavirus (Hpv) Dna in focal epithelial hyperplasia, J. Oral Pathol. Med. 18: 172–177 (1989).

    Article  PubMed  CAS  Google Scholar 

  87. Gissmann, L., Wolnik, L., Ikenberg, H., Koldovsky, U., And Schnurch, H. G., Human papillomavirus types 6 and 11 Dna sequences in genital and laryngeal papillomas and in some cervical cancers, Proc. Natl. Acad. Sci. Usa 80: 560–563 (1983).

    Article  PubMed  CAS  Google Scholar 

  88. Glinski, W., Obalek, S., Jablonska, S., And Orth, G., T cell defect in patients with epidermodysplasia verruciformis due to human papillomavirus type 3 and 5, Dermatologica 162: 141–147 (1981).

    Article  PubMed  CAS  Google Scholar 

  89. Goldberg, G. L., Vermund, S. H., Schiffman, M. H., Ritter, D. B., Spitzer, C., And Burk, R. D., Comparison of cytobrush and cervicovaginal lavage sampling methods for the detection of genital human papillomavirus, Am. J. Obstet. Gynecol. 161: 1669–1672 (1989).

    Article  PubMed  CAS  Google Scholar 

  90. Gravitt, P. E., And Manos, M. M., Polymerase chain reaction-based methods for the detection of human papillomavirus Dna, in: The Epidemiology of Human Papillomavirus and Cervical Cancer (N. Munoz, E X. Bosch, K. V. Shah, And A. Meheus, Eds.), pp. 121–133, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  91. Greenberg, M. D., Campion, M. J., And Rutledge, L. H., Cervicography as an adjunct to cytologic screening, Obstet. Gynecol. Clin. North Am. 20 (1): 13–29 (1993).

    PubMed  CAS  Google Scholar 

  92. Greer, C. E., Lund, J. K., And Manos, M. M., Pcr amplification from paraffin-embedded tissues: Recommendations on fixatives for long-term storage and prospective studies, Pcr Methods . 1: 46–50 (1991).

    Article  PubMed  CAS  Google Scholar 

  93. Gregoire, L., Lawrence, W. D., Kukuruga, D., Eisenbrey, A. B., And Lancaster, W. D., Association between Hla-Dqb1 alleles and risk for cervical cancer in African-American women, Int. J. Cancer 57: 504–507 (1994).

    Article  PubMed  CAS  Google Scholar 

  94. Nindl, I., Benitez-Bribiesca, L., Berumen, J., Farmanara, N., Fisher, S., Gross, A., Lopez-Carillo, L., Muller, M., Tommasino, M., Vazquez-Curiel, A., ET AL., Antibodies against linear and conformational epitopes of the human papil- lomavirus (Hpv) type 16 E6 and E7 oncoproteins in sera of cervical cancer patients, Arch. Virol. 137 (3–4): 341–353 (1994).

    Article  PubMed  CAS  Google Scholar 

  95. Guerrero, E., Daniel, R. W., Bosch, X., Castellsague, X., Munoz, N., Gili, M., Viladiu, P, Navarro, C., Zubiri, M. L., Ascunce, N., Gonzalez, L C, Tafur, L., Izarzugaza, I., And Shah, K. V., Comparison of virapap, Southern hybridization, and polymerase chain reaction methods for human papillomavirus identification in an epidemiological investigation of cervical cancer, J. Clin. Microbiol. 30 (11): 2951–2959 (1992).

    PubMed  CAS  Google Scholar 

  96. Gutman, L. T., ST. Claire, K., Herman-Giddens, M. E., Johnston, W. W., And Phelps, W. C., Evaluation of sexually abused and nonabused young girls for intravaginal human papillomavirus infection, Am. J. Dis. Child. 146: 694–699 (1992).

    PubMed  CAS  Google Scholar 

  97. Heck, D. V, Yee, C. L., Howley, R M., And Monger, K., Efficiency of binding the retinoblastoma protein correlates with the tranforming capacity of the E7 oncoproteins of the human papil- lomaviruses, Proc. Natl. Acad. Sci. Usa 89: 4442–4446 (1992).

    Article  PubMed  CAS  Google Scholar 

  98. Heino, P., Eklund, C., Fredriksson-Shanazarian, V, Gold-Man, S., Schiller, J. T., And Dillner, J., Association of serum immunoglobulin G antibodies against human papillomavirus type 16 capsids with anal epidermoid carcinoma, J. Natl. Cancer Inst. 87: 437–440 (1995).

    Article  PubMed  CAS  Google Scholar 

  99. Herrero, R., Brinton, L. A., Reeves, W. C., Brenes, M. M., Tenorio, E, DE Britton, R. C., Gaitan, E., Garcia, M., And Rawls, W. E., Invasive cervical cancer and smoking in Latin America, J. Natl. Cancer Inst. 81 (3): 205–211 (1989).

    Article  PubMed  CAS  Google Scholar 

  100. Hildesheim, A., Brinton, L. A., Szklo, M., Reeves, W. C., And Rawls, W. E., Herpes simplex virus 2: A possible interaction with human papillomavirus types 16/18 in the development of invasive cervical cancer, Int. J. Cancer 49: 335–340 (1991).

    Article  PubMed  CAS  Google Scholar 

  101. Hildesheim, A., Gravitt, P., Schiffman, M. H., Kurman, R. J., Barnes, W., Jones, S., Tchabo, J. G., Brinton, L. A., Cope-Land, C., Epp, J., And Manos, M. M., Determinants of genital human papillomavirus infection in low-income women in Washington, DC, Sex. Transm. Dis. 20: 279–285 (1993).

    Article  PubMed  CAS  Google Scholar 

  102. Hildesheim, A., Schiffman, M. H., Gravitt, R, Glass, A. G., Greer, C., Zhang, T., Scott, D. R., Rush, B. B., Lawler, P., Sherman, M. E., Kurman, R. J., And Manos, M. M., Persistence of type-specific human papillomavirus infection among cytologically normal women in Portland, Oregon, J. Infect. Dis. 169: 235–240 (1994).

    Article  PubMed  CAS  Google Scholar 

  103. Hippelainen, M., Eskelinen, M., Lipponen, P, Chang, F., And Syrjanen, K., Mitotic activity index, volume corrected mitotic index and human papillomavirus suggestive morphology are not prognostic factors in carcinoma of the oesophagus, Anticancer Res. 13: 677–682 (1993).

    PubMed  CAS  Google Scholar 

  104. Ho, G. Y. E, Burk, R. D., Fleming, I., And Klein, R. S., Risk of genital human papillomavirus infection in women with human immunodeficiency virus-induced immunosuppression, Int. J. Cancer 56 (6): 788–792 (1994).

    Article  PubMed  CAS  Google Scholar 

  105. Ho, L., Tay, S. K., Chan, S. Y., And Bernard, H. U., Sequence variants of human papillomavirus type 16 from couples suggests sexual transmission with low infectivity and polyclonality in genital neoplasia, J. Infect. Dis. 168: 1–7 (1993).

    Article  Google Scholar 

  106. Ho, L., Chan, S. Y., Chow, V., Cong, T., Tay, S. K., Villa, L. L., And Bernard, H. U., Sequence variants of human papillomavirus type 16 in clinical samples permit verification and extension of epidemiological studies and construction of a phylogenetic tree, J. Clin. Microbiol. 29 (9): 1765–1772 (1991).

    PubMed  CAS  Google Scholar 

  107. Holladay, E. B., And Gerald, W. L., Viral gene detection in oral neoplasms using the polymerase chain reaction, Am. J. Clin. Pathol. 100: 36–40 (1993).

    PubMed  CAS  Google Scholar 

  108. Hollingsworth, T. H., The incidence of warts and plantar warts amongst school children in East Anglia, Med. Officer 55–59 (1955).

    Google Scholar 

  109. Howley P. M., Papillomaviridae and their replication, in: Virology (B. N. Fields And D. M. Knipe, Eds.), Raven Press, New York, 1990.

    Google Scholar 

  110. Huibregtse, J. M., Scheffner, M., And Howley, P M., Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins, Mol. Cell. Biol. 13:4918–4927 (1993). Iarc Monograph on the Evaluation of Carcinogenic Risks to Humans: Vol. 64. Human Papillomaviruses. Iarc Scientific Publications, Lyon, France, 1995.

    Google Scholar 

  111. Janniger, C. K., Childhood warts, Pediatr. Dermatol. 50: 15–16 (1992).

    CAS  Google Scholar 

  112. Jarrett, W. E H., Mcneil, R E., Grimshaw, W. T. R., Selman, I. E., And Mcintyre, W. I. M., High incidence area of cattle cancer with a possible interaction between an environmental carcinogen and a papilloma virus, Nature 274: 215–217 (1978).

    Article  PubMed  CAS  Google Scholar 

  113. Jenison, S. A., Yu, X., Valentine, J. M., Koutsky, L. A., Christansen, A. E., Beckmann, A. M., And Galloway, D. A., Evidence of prevalent genital-type human papillomavirus infections in adults and children, J. Infect. Dis. 62: 60–69 (1990).

    Article  Google Scholar 

  114. Jochmus-Kudielka, L, Schneider, A., Braun, R., Kimmig, R., Koldovsky, U., Schneweis, K. E., Seedorf, K., And Gissmann, L., Antibodies against the human papillomavirus type 16 early proteins in human sera: Correlation of anti-E7 reactivity with cervical cancer, J. Natl. Cancer Inst. 81: 1698–1704 (1989).

    Article  Google Scholar 

  115. Johnson, M. L. T., And Roberts, J., Skin conditions and related need for medical care among persons 1–74 years: United States, 1971–1974, Natl. Center Health Stat. 11 (212): 1–72 (1978).

    Google Scholar 

  116. Kadish, A. S., Hagan, R. J., Ritter, D. B., Goldberg, G. L., Romney, S. L., Kanetsky, R. A., Beiss, B. K., And Burk, R. D., Biologic characteristics of specific human papillomavirus types predicted from morphology of cervical lesions, Hum. Pathol. 23 (11): 1262–1269 (1992).

    Article  PubMed  CAS  Google Scholar 

  117. Kadish, A. S., Romney, S. L., Ledwidge, R., Tindle, R., Fernando, G. J. R, And Zee, S. Y., Cell-mediated immune responses to E7 peptides of human papillomavirus type 16 are dependent on the Hpv type infecting the cervix whereas serological reactivity is not type-specific, J. Gen. Virol. 75 (9): 2277–2284 (1994).

    Article  PubMed  Google Scholar 

  118. Kadish, A. S., Romney, S. L., Ledwidge, R., Tindle, R., Fernando, G. J., Zee, S. Y., Van Ranst, M. A., And Burk, R. D., Cell-mediated immune responses to E7 peptides of human papillomavirus (Hpv) type 16 are dependent on the Hpv type infecting the cervix whereas serological reactivity is not type-specific, J. Gen. Virol. 75 (Part 9): 2277–2284 (1994).

    Article  PubMed  Google Scholar 

  119. Kaebling, M., Burk, R. D., Atkin, N. B., And Klinger, H. R, Loss of heterozygosity in the region of the TP53 gene on chromosome 17p in Hpv-negative human cervical carcinomas, Lancet 340: 140–142 (1992).

    Article  Google Scholar 

  120. Kasher, M. S., And Roman, A., Characterization of human papillomavirus type 6B Dna isolated from an invasive squamous carcinoma of the vulva, Virology 165: 225–233 (1988).

    Article  PubMed  CAS  Google Scholar 

  121. Kashima, H. K., Shah, F., Lyles, A., Glackin, R., Muhammad, N., Turner, L., Van Zandt, S., Whitt, S., And Shah, K., A comparison of risk factors in juvenile-onset and adult-onset recurrent respiratory papillomatosis, Laryngoscope 102: 9–13 (1992).

    PubMed  CAS  Google Scholar 

  122. Kasperbauer, J. L., O’Halloran, G. L., Espy, J. J., Smith, T. F., And Lewis, J. E., Polymerase chain reaction (Pcr) identification of human papillomavirus (Hpv) Dna in verrucous carcinoma of the larynx, Laryngoscope 103: 416–420 (1993).

    Article  PubMed  CAS  Google Scholar 

  123. Kataja, V., Syrjanen, K., Syrjanen, S., Mantyjarvi, R., Yliskoski, M., Saarikoski, S., And Salonen, J. T., Prospective follow-up of genital Hpv infections: Survival analysis of the Hpv typing data, Eur. J. Epidemiol. 6 (1): 9–14 (1990).

    Article  PubMed  CAS  Google Scholar 

  124. Keefe, M., AL-Ghamdi, A., Coggon, D., Maitland, N. J., Egger, R, And Keefe, C. J., Cutaneous warts in butchers, Br. J. Dermatol. 130: 9–14 (1994).

    Article  PubMed  CAS  Google Scholar 

  125. Kirnbauer, R., Hubbert, N. L., Wheeler, C. M., Becker, T. M., Lowe D. R., And Schiller, J. T., A virus-like particle Elisa detects serum antibodies in a majority of women infected with human papillomavirus type 16, J. Natl. Cancerinst. 86: 494499 (1994).

    Google Scholar 

  126. Kiviat, N. B., Critchlow, C. W., Holmes, K. K., Kuypers, J., Sayer, J., Dunphy, C., Surawicz, C., Kirby, P., Wood, R., And Daling, J. R., Association of anal dysplasia and human papillomavirus with immunosuppression and Hiv infection among homosexual men, Aid 7: 43–49 (1993).

    Article  PubMed  CAS  Google Scholar 

  127. Kiviat, N. B., Critchlow, C. W., And Kurman, R. J., Reassessment of the morphological continuum of cervical intraepithelial lesions: Does it reflect different stages in the progression to cervical carcinoma? in: The Epidemiology of Human Papillomavirus and Cervical Cancer (N. Munoz, E X. Bosch, K. V. Shah, And A. Meheus, EDs.), pp. 59–66, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  128. Kiviat, N. B., Koutsky, L. A., Critchlow, C. W., Galloway, D. A., Vernon, D. A., Peterson, M. L., Mcelhose, P. E., Pendras, S. J., Stevens, C. E., And Holmes, K. K., Comparison of Southern transfer hybridization and dot filter hybridization for detection of cervical human papillomavirus infection with types 6, 11, 16, 18, 31, 33, and 35, Am. J. Clin. Pathol. 94 (5): 561–565 (1990).

    PubMed  CAS  Google Scholar 

  129. Kjaer, S. K., And Brinton, L. A., Adenocarcinomas of the uterine cervix: The epidemiology of an increasing problem, Epidemiol. Rev. 15: 486–498 (1993).

    PubMed  CAS  Google Scholar 

  130. Kjaer, S. K., And Jensen, O. M., Comparison studies of Hpv detection in areas at different risk for cervical cancer, in: The Epidemiology of Human Papillomavirus and Cervical Cancer (N. Munoz, E X. Bosch, K. V. Shah, And A. Meheus, Eds.), pp. 243–249, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  131. Kochel, H. G., Monazahian, M., Sievert, K., HoHne, M., Thomssen, C., Teichmann, A., Arendt, R, And Thomssen, R., Occurrence of antibodies to Ll, L2, E4 and E7 gene products of human papillomavirus types 6b, 16 and 18 among cervical cancer patients and controls, Int. J. Cancer 48: 682–688 (1991).

    Article  PubMed  CAS  Google Scholar 

  132. Kohno, T., Takayama, H., Hamaguchi, M., Takano, H., Yamaguchi, N., Tsuda, H., Hiroi-Iashi, S., Vissing, H., Shimizu, M., Oshimura, M., Deletion mapping of chromosome 3p in human uterine cervical cancer, Oncogene 8: 1825–1832 (1993).

    PubMed  CAS  Google Scholar 

  133. Kosary, C. L., Schiffman, M. H., And Trimble, E. L., Cervix uteri, in: Seer Cancer Statistics Review: 1973–1990 (B. A. Miller, L. A. G. Ries, B. E Hankey, C. L. Kosary, A. Harras, S. S. Devesa, And B. K. Edwards, Eds.), Section V, National Cancer Institute Nih Pub. No. 93–2789, Bethesda, 1994.

    Google Scholar 

  134. Koss, L. G., From koilocytosis to molecular biology: The impact of cytology on concepts of early human cancer, Mod. Pathol. 2 (5): 526–535 (1989).

    PubMed  CAS  Google Scholar 

  135. Koutsky, L. A., Galloway, D. A., And Holmes, K. K., Epidemiology of genital human papillomavirus infection, Epidemiol. Rev. 10: 122–163 (1988).

    PubMed  CAS  Google Scholar 

  136. Koutsky, L. A., Holmes, K. K., Critchlow, C. W., Stevens, C. E., Paavonen, J., Beckmann, A. M., Derouen, T. A., Galloway, D. A., Vernon, D., And Kiviat, N. B., A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection, New Engl. J. Med. 327 (18): 1272–1278 (1992).

    Article  PubMed  CAS  Google Scholar 

  137. Krebs, H. B., And Schneider, V., Human papillomavirus-associated lesions of the penis: Colposcopy, cytology, and histology, Obstet. Gynecol. 70 (3): 299–304 (1987).

    PubMed  CAS  Google Scholar 

  138. Kreider, J. W., Howett, M. K., Wolfe, S. A., Bartlett, G. L., Zaino, R. J., Sedlacek, T. V., And Mortel, R., Morphological transformation in vivo of human uterine cervix with papillomavirus from conylomata acuminata, Nature 317 (17): 639–641 (1985).

    Article  PubMed  CAS  Google Scholar 

  139. Kreiss, J. K., Kiviat, N. B., Plummer, E A., Roberts, R L., Waiyaki, P., Ngugi, E., And Holmes, K. K., Human immunodeficiency virus, human papillomavirus, and cervical intraepithelial neoplasia in Nairobi prostitutes, Sex. Transm. Dis. 19: 54–59 (1992).

    Article  PubMed  CAS  Google Scholar 

  140. Kurman, R. J., Schiffman, M. H., Lancaster, W. D., Reid, R., Jenson, A. B., Temple, G. F., And Lorincz, A. T., Analysis of individual human papillomavirus types in cervical neoplasia: A possible role for type 18 in rapid progression, Am. J. Obstet. Gynecol. 159 (2): 293–296 (1988).

    PubMed  CAS  Google Scholar 

  141. Kurman, R. J., Shah, K. H., Lancaster, W. D., And Jenson, A. B., Immunoperoxidase localization of papillomavirus antigens in cervical dysplasia and vulvar condylomas, Am. J. Obstet. Gynecol. 140: 931–935 (1981).

    PubMed  CAS  Google Scholar 

  142. Kurman, R. J., And Solomon, D., The Bethesda System for Reporting Cervical/Vaginal Cytologic Diagnoses, Springer-Verlag, New York, 1994.

    Book  Google Scholar 

  143. Kurman, R. J., Toles, T., And Schiffman, M. H., Basaloid and warty carcinomas of the vulva: Distinctive types of squamous cell carcinoma frequently associated with human papillomavirus, Am. J. Surg. Pathol. 17: 133–145 (1993).

    Article  PubMed  CAS  Google Scholar 

  144. Lancaster, W. D., And Olson, C., Animal papillomaviruses, Microbiol. Rev. 46 (2): 191–207 (1982).

    PubMed  CAS  Google Scholar 

  145. Laverty, C. R., Russell, P., Hills, E., And Boom, N., The significance of noncondylomatous wart virus infection of the cervical transformation zone. A review with discussion of two illustrative cases, Acta Cytol. 22: 195–201 (1978).

    PubMed  CAS  Google Scholar 

  146. Lawton, G., Thomas, S., Schonrock, J., Monsour, E, And Frazer, I., Human papillomaviruses in normal oral mucosa: A comparison of methods for sample collection, J. Oral Pathol. Med. 21: 265–269 (1992).

    Article  PubMed  CAS  Google Scholar 

  147. Lee, N. K., Ritter, D. B., Gross, A. E., Myssioreck, D. J., Kadish, A. S., And Burk, R. D., Head and neck squamous cell carcinomas associated with human papillomaviruses and an increased incidence of cervical pathology, Otolaryngol. Head Neck Surg. 99: 296–301 (1988).

    PubMed  CAS  Google Scholar 

  148. Ley, C., Bauer, H. M., Reingold, A., Schiffman, M. H., Chambers, J. C., Tashiro, C. J., And Manos, M. M., Determinants of genital papillomavirus infection in young women, J. Natl. Cancer Inst. 83: 997–1003 (1991).

    Article  PubMed  CAS  Google Scholar 

  149. Lorincz, A. T., Human papillomavirus detection tests, in: Sexually Transmitted Diseases, 2nd ed. (K. K. Holmes, P. A. Mardh, P. E Sparling, P. J. Wiesner, W. Cates, S. M. Lemon, And W. E. Stamm, Eds.), pp. 953–959, McGraw-Hill, New York, 1990.

    Google Scholar 

  150. Lorincz, A. T., Detection of human papillomavirus Dna without amplications: Prospects for clinical utility, in: The Epidemiology of Human Papillomavirus and Cervical Cancer (N. MuNoz, E X. Bosch, K. V. Shah, And A. Meheus, Eds.), pp. 85–92, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  151. Lorincz, A. T., Reid, R., Jenson, A. B., Greenberg, M. D., Lancaster, W., And Kurman, R. J., Human papillomavirus infection of the cervix: Relative risk associations of 15 common anogenital types, Obstet. Gynecol. 79: 328–337 (1992).

    Article  PubMed  CAS  Google Scholar 

  152. LoIuNcz, A. T., Schiffman, M. H., Jaffurs, W. J., Marlow, J., Quinn, A. P., And Temple, G. F., Temporal associations of human papillomavirus infection with cervical cytologic abnormalities, Am. J. Obstet. Gynecol. 162: 645–651 (1990).

    Google Scholar 

  153. Maiman, M., Fructher, R. G., Guy, L., Cuthill, S., Levine, P., And Serur, E., Human immunodeficiency virus infection and invasive cervical carcinoma, Cancer 71: 402–406 (1993).

    Article  PubMed  CAS  Google Scholar 

  154. Majoros, M., Devine, K. D., And Parkhill, E. M., Malignant transformation of benign laryngeal papillomas in children after radiation therapy, Surg. Clin. North Am. 43: 1049–1061 (1963).

    PubMed  CAS  Google Scholar 

  155. Manos, M. M., Ting, Y., Wright, D. K., Lewis, A. J., Broker, T. R., And Wolinsky, S. M., Use of polymerase chain reaction amplification for the detection of genital human papillomavirus, Mol. Diagn. Hum. Cancer 7: 209–214 (1989).

    CAS  Google Scholar 

  156. Mansell, M. E., HO, L., Terry, G., Singer, A., And Cuzick, J., Semi-quantitative human papillomavirus Dna detection in the management of women with minor cytological abnormality, Br. J. Obstet. Gynaecol. 101 (9): 807–809 (1994).

    Article  PubMed  CAS  Google Scholar 

  157. Masih, A. S., Stoler, M. H., Farrow, G. M., And Johansson, S. L., Human papillomavirus in penile squamous cell lesions: A comparison of an isotopic Rna and two commercial nonisotopic Dna in situ hybridization methods, Arch. Pathol. Lab. Med. 117: 302–307 (1993).

    PubMed  CAS  Google Scholar 

  158. Massing, A. M., And Epstein, W. L., Natural history of warts, Arch. Dermatol. 87: 74–78 (1963).

    Article  Google Scholar 

  159. Mcdonnell, J. M., Mayr, A. J., And Martin, W. J., Dna of human papillomavirus type 16 in dysplastic and malignant lesions of the conjunctiva and cornea, New Engl. J. Med. 320(22):14421446 (1989).

    Google Scholar 

  160. Mcglennen, R. C., Ghai, J., Ostrow, R. S., Labresh, K., Schneider, J. F., And Faras, A. J., Cellular transformation by a unique isolate of human papillomavirus type 11, Cancer Res. 52: 5872–5878 (1992).

    PubMed  CAS  Google Scholar 

  161. McNicol, P. J., And Dodd, J. G., High prevalence of human papillomavirus in prostate tissues, J. Urol. 145: 850–853 (1991).

    Google Scholar 

  162. Meisels, A., And Fortin, R., Condylomatous lesions of the cervix and vagina I. Cytologic patterns, Acta Cytol. 20(6):505509 (1976).

    Google Scholar 

  163. Melbye, M., Palefsky, J., Gonzales, J., Ryder, L. E, Nielsen, H., Bergmann, O., Pindeorg, J., And Biggar, R. J., Immune status as a determinant of human papillomavirus detection and its association with anal epithelial abnormalties, Int. J. Cancer 46: 203–206 (1990).

    Article  PubMed  CAS  Google Scholar 

  164. Melbye, M., And Sprogel, P., Aetiological parallel between anal cancer and cervical cancer, Lancet 338: 657–659 (1991).

    Article  PubMed  CAS  Google Scholar 

  165. Melkert, P. W. J., Hopman, E., Van Den Brule, A. J. C., Risse, E. K. J., Van Diest, P. J., Bleker, O. P., Helmerhorst, T., Schipper, M. E. I., Meijer, C. J. L. M., And Walboomers, J. M. M., Prevalence of Hpv in cytomorphologically normal cervical smears, as determined by the polymerase chain reaction, is age-dependent, Int. J. Cancer 53: 919–923 (1993).

    Article  PubMed  CAS  Google Scholar 

  166. Melnick, J. L., Papova virus group, Science 135: 1128–1130 (1962).

    Article  PubMed  CAS  Google Scholar 

  167. Meyers, C., Frattini, M. G., Hudson, J. B., And Laimins, L. A., Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation, Science 257: 971–973 (1992).

    Article  PubMed  CAS  Google Scholar 

  168. Meyskens, E L., JR., Surwit, E., Moon, T. E., Childers, J. M., Davis, J. R., Dorr, R. T., Johnson, C. S., And Alberts, D. S., Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: A randomized trial, J. Natl. Cancer Inst. 86: 539–543 (1994).

    Article  PubMed  Google Scholar 

  169. Monsonego, J., Magdelenat, H., Catalan, E, Coscas, Y., Zerat, L., And Sastre, X., Estrogen and progesterone receptors in cervical human papillomavirus related lesions, Int. J. Cancer 48: 533–539 (1991).

    Article  PubMed  CAS  Google Scholar 

  170. Morelli, A. E., Sananes, C., Dipaola, G., Paredes, A., And Fainboim, L., Relationship between types of human papillomavirus and Langerhans’ cells in cervical condyloma and intraepithelial neoplasia, Am. J. Clin. Pathol. 99: 200–206 (1993).

    PubMed  CAS  Google Scholar 

  171. Morrison, E. A., Goldberg, G. L., Hagan, R. J., Kadish, A. S., And Burk, R. D., Self-administered home cervicovaginal lavage: A novel tool for the clinical-epidemiological investigation of genital human papillomavirus infections, Am. J. Obstet. Gynecol. 167 (1): 104–107 (1992).

    Article  PubMed  CAS  Google Scholar 

  172. Morrison, E. A. B., Classification of human papillomavirus infection, J.A.M.A. 270 (4): 453 (1993).

    PubMed  CAS  Google Scholar 

  173. Morrison, E. A. B., Ho, G. Y. E, Vermund, S. H., Goldberg, G. L., Kadish, A. S., Kelly, K. E, And Burk, R. D., Human papillomavirus infection and other risk factors for cervical neoplasia: A case-control study, Int. J. Cancer 49: 6–13 (1991).

    Article  PubMed  CAS  Google Scholar 

  174. MoscrCki, A. B., Comparison between methods for human papillomavirus Dna testing: A model for self-testing in young women, J. Infect. Dis. 167: 723–725 (1993).

    Article  Google Scholar 

  175. Moscicki, A. B., Palefsky, J., Smith, G., Siboshski, S., And Schoolnik, G., Variability of human papillomavirus Dna testing in a longitudinal cohort of young women, Obstet. Gynecol. 82: 578–585 (1993).

    PubMed  CAS  Google Scholar 

  176. MouGin, C., Schaal, J. P., Bassignot, A., Madoz, L., Coaquette, A., Laurent, R., And Lab, M., Detection of human papillomavirus and human cytomegaldvirus in cervical lesions by in situ hybridization using biotinylated probes, Biomed. Pharmarcother. 45: 353–357 (1991).

    Article  Google Scholar 

  177. Muller, M., Viscidi, R., Sun, Y., Guerrero, E., Hill, P. M., Shah, F., Bosch, X., Munoz, N., Gissmann, L., And Shah, K. V., Antibodies to Hpv-16 E6 and E7 proteins as markers for Hpv-16-associated invasive cervical cancer, Virology 187: 508514 (1992).

    Google Scholar 

  178. Munoz, N., Bosch, E X., Desanjose, S., Tafur, L., Izarzugaza, I., Gili, M., Viladiu, P, Navarro, C., Martos, C., Ascunce, N., Gonzalez, L. C., Kaldor, J. M., Guerrero, E., Lorincz, A., Santamaria, M., Deruiz, P. A., Aristizabal, N., And Shah, K., The causal link between human papillomavirus and invasive cervical cancer: A population-based case-control study in Columbia and Spain, Int. J. Cancer 52: 743–749 (1992).

    Article  PubMed  CAS  Google Scholar 

  179. Munoz, N., Bosch, F. X., Desanjose, S., Vergara, A., Delmora, A., Munoz, M. T., Tafur, L., Gili, M., Izarzugaza, I., Viladiu, P., Navarro, C., Alonso DE Ruiz, P., Aristizabal, N., Santamaria, M., Orfila, J., Daniel, R. W., Guerrero, E., And Shah, K. V., Risk factors for cervical intraepithelial neoplasia grade Iii/ carcinoma in situ in Spain and Columbia, Cancer Epidemiol. Biomarkers Prey. 2: 423–431 (1993).

    CAS  Google Scholar 

  180. Munoz, N., Bosch, X., And Kaldor, J. M., Does human papillomavirus cause cervical cancer? The state of the epidemiological evidence, Br. J. Cancer 57 (1): 1–5 (1988).

    Article  PubMed  CAS  Google Scholar 

  181. Nasiell, K., Roger, V., And Nasiell, M., Behavior of mild cervical dysplasia during long-term follow-up, Obstet. Gynecol. 67: 665–669 (1986).

    Article  PubMed  CAS  Google Scholar 

  182. Nuovo, G., Evidence against a role for human papillomavirus in colon neoplasms, Arch. Surg. 126: 656 (1991).

    Article  PubMed  CAS  Google Scholar 

  183. Obalek, S., Glinski, W., Haftek, M., Orth, G., And Jablonska, S., Comparative studies on cell-mediated immunity in patients with different warts, Dermatologica 161: 73–83 (1980).

    Article  PubMed  CAS  Google Scholar 

  184. Okagaki, T., Female genital tumors associated with human papillomavirus infection, and the concept of genital neoplasmpapilloma syndrome (Genps), Pathol. Annu. 19 (2): 31–62 (1993).

    Google Scholar 

  185. Ong, C. K., Chan, S. Y., Campo, M. S., Fujinaga, K., Mavromara, P., Pfister, H., Tay, S. K., Meulen, J. T., Villa, L. L., And Bernard, H. U., Evolution of human papillomavirus type 18: An ancient phylogenetic root in Africa and intratype diversity reflect coevolution with human ethnic groups, J. Virol. 67: 6424–6431 (1993).

    PubMed  CAS  Google Scholar 

  186. Oriel, J. D., Sex and cervical cancer, Genitourin. Med. 64: 81–89 (1988).

    PubMed  CAS  Google Scholar 

  187. Orth, G., Favre, M., Breitburd, F., Croissant, O., Jablonska, S., Obalek, S., Jarzabek-Chorzelsak, M., And Rzesa, G., Epidermodysplasia verruciformis: A model for the role of papillomaviruses in human cancer, in: Cold Spring Harbor Conference on Cell Proliferation, Vol. 7, Cold Spring Harbor, New York, 1980.

    Google Scholar 

  188. Pakarian, F, Kaye, J., Cason, J., Kell, B., Jewers, R., DE-Rias, N. W., Raju, K. S., And Best, J. M., Cancer associated human papillomaviruses: Perinatal transmission and persistence, Br. J. Obstet. Gynaecol. 101: 514–517 (1994).

    Article  PubMed  CAS  Google Scholar 

  189. Palefsky, J., Human papillomavirus infection among Hiv- infected individuals, implications for development of malignant tumors, Hematol. Oncol. Aspects Hiv Dis. 5 (2): 357–370 (1991).

    CAS  Google Scholar 

  190. Palefsky, J. M., Gonzales, J., Greenblatt, R. M., Ahn, D. K., And Hollander, H., Anal intraepithelial neoplasia and anal papillomavirus infection among homosexual males with group IV Hiv disease, J.A.M.A. 263 (21): 2911–2916 (1990).

    Article  PubMed  CAS  Google Scholar 

  191. Palefsky, J. M., Holly, E. A., Gonzales, J., Berline, J., Ahn, D. K., And Greenspan, J. S., Detection of human papillomavirus Dna in anal intraepithelial neoplasia and anal cancer, Cancer Res. 51: 1014–1019 (1991).

    PubMed  CAS  Google Scholar 

  192. Parkin, D. M., Pisani, P, And Ferlay, J., Estimates of the worldwide frequency of eighteen major cancers in 1985, Int. J. Cancer 54: 594–606 (1993).

    Article  PubMed  CAS  Google Scholar 

  193. Patsner, B., Baker, D. A., And Orr, J. W., Human papillomavirus genital tract infections during pregnancy, Clin. Ob-stet. Gynecol. 33: 258–267 (1990).

    Article  CAS  Google Scholar 

  194. Petry, K. U., Scheffel, D., Bode, U., Gabrysiak, T., Kochel, H., Kupsch, E., Glaubitz, M., Niesert, S., Kuhnle, H., And Schedel, I., Cellular immunodeficiency enhances the progression of human papillomavirus-associated cervical lesions, Int. J. Cancer 57: 836–840 (1995).

    Article  Google Scholar 

  195. Pfister, H., And Zur Hausen, H., Seroepidemiological studies of human papilloma virus (Hpv-1) infections, Cancer 21: 161–165 (1978).

    CAS  Google Scholar 

  196. Popescu, N. C., And Dipaolo, J. A., Preferential sites for viral integration on mammalian genome, Cancer Genet. Cytogenet. 42: 157–171 (1989).

    Article  PubMed  CAS  Google Scholar 

  197. Potischman, N., Nutritional epidemiology of cervical neoplasia, J. Nutr. 123: 424–429 (1993).

    PubMed  CAS  Google Scholar 

  198. Purola, E., And Savia, E., Cytology of gynecologic condyloma acuminatum, Acta Cytol. 21: 26–31 (1977).

    PubMed  CAS  Google Scholar 

  199. Rasmussen, K. A., Verrucae Plantares: Symptomatology and Epidemiology, Copenhagen, 1958.

    Google Scholar 

  200. Reid, R, Herschman, B. R., Crum, C. P., Fu, Y. S., Braun, L., Shah, K. V., Agronow, S. J., And Stanhope, C. R., Genital warts and cervical cancer, Am. J. Obstet. Gynecol. 149: 293–303 (1984).

    PubMed  CAS  Google Scholar 

  201. Richart, R. M., And Barron, B. A., A follow-up study of patients with cervical dysplasia, Am. J. Obstet. Gynecol. 105 (3): 386–393 (1969).

    PubMed  CAS  Google Scholar 

  202. Ries, L. A. G., Miller, B. A., And Hankey, B. F., Seer Cancer Statistics Review: 1973–1991-Tables and Graphs, Nih Pub. No. 94–2789, Bethesda, 1994.

    Google Scholar 

  203. Ritter, D. B., Kadish, A. S., Vermund, S. H., Romney, S. L., Villari, D., And Burk, R. D., Detection of human papillomavirus deoxyribonucleic acid in exfoliated cervicovaginal cells as a predictor of cervical neoplasia in a high-risk population, Am. J. Obstet. Gynecol. 159 (6): 1517–1525 (1988).

    PubMed  CAS  Google Scholar 

  204. Roche, J. K., And Crum, C. R, Local immunity and the uterine cervix: Implications for cancer-associated viruses, Cancer Immunol. Immunother 33: 203–209 (1991).

    Article  PubMed  CAS  Google Scholar 

  205. Rohan, T., Mann, V., Mclaughlin, J., Harnish, D. G., YU, H., Smith, D., Davis, R., Shier, R. M., And Rawls, W., Pcrdetected genital papillomavirus infection: Prevalence and association with risk factors for cervical cancer, Int. J. Cancer 49: 856–860 (1991).

    Article  PubMed  CAS  Google Scholar 

  206. Roman, A., And Fife, K., Human papillomavirus Dna associated with foreskins of normal newborns, J. Infect. Dis. 153: 855861 (1986).

    Google Scholar 

  207. RooK, A., Virus and related infections, in: Textbook of Dermatology, 4th ed. (A. RooK, D. S. Wilkinson, F. J. G. Ebling, R. H. Champion, And J. L. Burton, Eds.), pp. 668–679, Blackwell Scientific Publications, London, 1986.

    Google Scholar 

  208. Rose, R. C., Bonnez, W., Reichman, R. C., And Garcea, R. L., Expression of human papillomavirus type 11 Ll protein in insect cells: In vivo and in vitro assembly of viruslike particles, J. Virol. 67: 1936–1944 (1993).

    PubMed  CAS  Google Scholar 

  209. Rosemberg, S. K., Sexually transmitted papillomaviral infection in men, Dermatol. Clin. 9 (2): 317–331 (1991).

    PubMed  CAS  Google Scholar 

  210. Rosemberg, S. K., Herman, G., And Elfont, E., Sexually transmitted papillomaviral infection in the male, Urology 37 (5): 437–440 (1991).

    Article  PubMed  CAS  Google Scholar 

  211. Rosenfeld, W. D., Rose, E., Vermund, S. H., Schreiber, K., And Burk, R. D., Follow-up evaluation of cervicovaginal human papillomavirus infection in adolescents, J. Pediatr 121: 301–311 (1992).

    Google Scholar 

  212. Rudlinger, R., Bunney, M. H., Grob, R., And Hunter, J. A. A., Warts in fish handlers, Br. J. Dermatol. 120: 375–381 (1989).

    Article  PubMed  CAS  Google Scholar 

  213. Schachner, L., Ling, N. S., And Press, S., A statistical analysis of a pediatric dermatology clinic, Pediatr. Dermatol. 1(2):157164 (1983).

    Google Scholar 

  214. Schairer, C., Brinton, L. A., Devesa, S. S., Ziegler, R. G., And Fraumeni, J. E, Racial differences in the risk of invasive squamous-cell cervical cancer, Cancer Causes Control 2: 283289 (1991).

    Google Scholar 

  215. Schiffman, M. H., Recent progress in defining the epidemiology of human papillomavirus infection and cervical neoplasia, J. Natl. Cancer Inst. 84 (6): 394–398 (1992).

    Article  PubMed  CAS  Google Scholar 

  216. Schiffman, M. H., Validation of Hpv hybridization assays: Correlation of Fish, dot blot, and Pcr with Southern blot, in: The Epidemiology of Human Papillomavirus and Cervical Cancer(N. Munoz, E X. Bosch, K. V. Shah, And A. Meheus, Eds.), pp. 169–179, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  217. Schiffman, M. H., Epidemiology of cervical human papillomaviruses, in: Human Pathogenic Papillomaviruse (H. Zur Hausen, ED.), pp. 55–81, Springer Verlag, Heidelberg, 1994.

    Google Scholar 

  218. Schiffman, M. H., Bauer, H. M., Hoover, R. N., Glass, A. G., Cadell, D. M., Rush, B. B., Scott, D. R., Sherman, M. E., Kurman, R. J., Wacholder, S., Stanton, C. K., And Manos, M. M., Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia, J. Natl. Cancer Inst. 85: 958–964 (1993).

    Article  PubMed  CAS  Google Scholar 

  219. Schiffman, M. H., Kiviat, N. B., Burk, R. D., Shah, K. V., Daniel, R. W., Lewis, R., Kuypers, J., Manos, M. M., Scott, D. R., Sherman, M. E., Kurman, R. J., Stoler, M. H., Glass, A. G., Rush, B. B., Mielzynska, L, And Lorincz, A. T., Accuracy and interlaboratory reliability of Hpv Dna testing using hybrid capture, J. Clin. Microbiol. 33: 545–550 (1995).

    PubMed  CAS  Google Scholar 

  220. Schiffman, M. H., Kurman, R. J., Barnes, W., And Lancaster, W. D., Hpv infection and early cervical cytological abnormalities in 3175 Washington, DC women, in: Papillomaviruses (P. Howley And T. R. Broker, Eds.), pp. 81–88, Wiley-Liss, New York, 1990.

    Google Scholar 

  221. Schiffman, M. H., And Schatzkin, A., Test reliability is critically important to molecular epidemiology: An example from studies of human papillomavirus infection and cervical neoplasia, Cancer Res. 54: 1944s - 1947s (1994).

    PubMed  CAS  Google Scholar 

  222. Schiffman, M. H., And Sherman, M. E., Hpv testing can be used to improve cervical cancer screening, in: Molecular Markers of Early Detection of Cancer, (S. Srivastava, ED.), pp. 265–277, Futura Publishing, Armonk, NY, 1994.

    Google Scholar 

  223. Schlegel, R., Phelps, W. C., Zhang, Y. L., And Barbosa, M., Quantitative keratinocyte assay detects two biological activities of human papillomavirus Dna and identifies viral types associ- ated with cervical carcinoma, Embo J. 7 (10): 3181–3187 (1988).

    PubMed  CAS  Google Scholar 

  224. Schneider, A., Kirchhoff, T., Meinhardt, G., And Gissmann, L., Repeated evaluation of human papillomavirus 16 status in cervical swabs of young women with a history of normal Papanicolaou smears, Obstet. Gynecol. 79 (5): 683–688 (1992).

    PubMed  CAS  Google Scholar 

  225. Schneider, A., And Koutsky, L. A., Natural history and epidemiological features of genital Hpv infection, in: The Epidemiology of Cervical Cancer and Human Papillomavirus (N. MuNoz, F. X. Bosch, K. V. Shah, And A. Meheus, Eds.), pp. 25–52, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  226. Schwartz, R. A., And Janniger, C. K., Bowenoid papulosis, J. Am. Acad. Dermatol. 24 (2): 261–264 (1991).

    Article  PubMed  CAS  Google Scholar 

  227. Shah, K., Kashima, H., Polk, F., Shah, F., Abbey, H., And Abramson, A., Rarity of cesarean delivery in cases of juvenile-onset respiratory papillomatosis, Obstet. Gynecol. 68: 795–799 (1986).

    PubMed  CAS  Google Scholar 

  228. Shah, K. V., Genital warts, papillomaviruses, and genital malignancies, Annu. Rev. Med. 39: 371–379 (1988).

    Article  PubMed  CAS  Google Scholar 

  229. Shah, K. V., And Howley, P. M., Papillomaviruses, in: urology (B. H. Fields, D. M. Knipe, And P. M. Howley, Eds.), pp. 20772109, Raven Press, New York, 1995.

    Google Scholar 

  230. Sherman, M. E., Schiffman, M. H., Erozan, Y. S., Wacholder, S., And Kurman, R. J., The Bethesda system: A proposal for reporting abnormal cervical smears based on the reproducibility of cytopathologic diagnoses, Arch. Pathol. 116: 1155–1158 (1992).

    CAS  Google Scholar 

  231. Sherman, M. E., Schiffman, M. H., Lorincz, A. T., Manos, M. M., Scott, D. R., Kurman, R. J., Kiviat, N. B., Stoler, M., Glass, A. G., And RusH, B. B., Towards objective quality assurance in cervical cytopathology: Correlation of cytopathologic diagnoses with detection of high risk human papillomavirus types, Am. J. Clin. Pathol. 101: 182–187 (1994).

    Google Scholar 

  232. Shroyer, K. R., Human papillomavirus and endocervical adenocarcinoma, Hum. Pathol. 24: 119–120 (1993).

    Article  PubMed  CAS  Google Scholar 

  233. Shroyer, K. R., Kim, J. G., Manos, M. M., Greer, C. E., Pearlman, N. W., And Franklin, W. A., Papillomavirus found in anorectal squamous carcinoma, not in colon adenocarcinoma, Arch. Surg. 127: 741–744 (1992).

    Article  PubMed  CAS  Google Scholar 

  234. Smith, E. M., Johnson, S. R., Jiang, D., Zaleski, S., Lynch, C. E, Brundage, S., Anderson, R. D., And Turek, L. P., The association between pregnancy and human papilloma virus prevalence, Cancer Detect. Prey. 15 (5): 397–402 (1991).

    CAS  Google Scholar 

  235. Smits, H. L., Tieben, L. M., Tjong-A-Hung, S. P., Jebbink, M. E, Minnaar, R. P., Jansen, C. L., And Ter Schegget, J., Detection and typing of human papillomaviruses present in fixed and stained archival cervical smears by a consensus polymerase chain reaction and direct sequence analysis allow the identification of a broad spectrum of human papillomavirus types, J. Gen. Virol. 73: 3263–3268 (1992).

    Google Scholar 

  236. Snijders, P. J. F., Van Den Brule, A. J. C., Schrijnemakers, H. F. J., Snow, G., Meijer, C. J. L. M., And Walboomers, J. M. M., The use of general primers in the polymerase chain reaction permits the detection of a broad spectrum of human papillomavirus genotypes, J. Gen. Virol. 71: 173–181 (1990).

    Article  PubMed  CAS  Google Scholar 

  237. Solomon, D., The 1988 Bethesda system for reporting cervical/ vaginal cytological diagnoses, J.A.M.A. 262 (6): 931–934 (1989).

    Google Scholar 

  238. Spitzer, M., Krumholz, B. A., And Seltzer, V. L., The multi-centric nature of disease related to human papillomavirus infection of the female lower genital tract, Obstet. Gynecol. 73 (3): 303–307 (1989).

    PubMed  CAS  Google Scholar 

  239. Srivatsan, E. S., Misra, B. C., Venugopalan, M., And Wilczynski, S. P., Loss of heterozygosity for alleles on chromosome 11 in cervical carcinoma, Am. J. Hum. Genet. 49: 868–877 (1991).

    PubMed  CAS  Google Scholar 

  240. Stanbridge, C. M., And Butler, E. B., Human papillomavirus infection of the lower female genital tract: Association with multicentric neoplasia, Int. J. Gynecol. Pathol. 2(3):264–274 (1983).

    Google Scholar 

  241. Steele, K., Irwin, W. G., And Merrett, J. D., Warts in general practice, Irish Med. J. 82 (3): 122–124 (1989).

    CAS  Google Scholar 

  242. Steinberg, B. M., Laryngeal papillomatosis is associated with a defect in cellular differentiation, Ciba Found. Symp. 120: 208220 (1986).

    Google Scholar 

  243. Steinberg, B. M., Abramson, A. L., Hirschfield, L., Kahn, L. B., And Freiberger, I., Vocal cord polyps: Biochemical and histologic valuation, Laryngoscope 95 (11): 1327–1331 (1985).

    Article  PubMed  CAS  Google Scholar 

  244. Stellato, G., Nieminen, P., Aho, H., Vesterinen, E., Vaheri, A., And Paavonen, J., Human papillomavirus infection of the female genital tract: Correlation of Hpv Dna with cytologic, colposcopic, and natural history findings, Eur. J. Gynecol. On-col. 13: 262–267 (1994).

    Google Scholar 

  245. Stoler, M. H., And Broker, T. R., In situ hybridization detection of human papillomavirus Dnas and messenger Rnas in genital condylomas and a cervical carcinoma, Hum. Pathol. 17: 1250–1258 (1986).

    Article  PubMed  CAS  Google Scholar 

  246. Strickler, H. D., Dillner, J., Schiffman, M. H., Manos, M. M., Glass, A. G., Greer, C. E., Scott, D. R., Sherman, M. E., And Kurman, R. J., A seroepidemiologic study of Hpv infection and incident cervical squamous intraepithelial lesions, Virol. Immunol. 7:169–177 (1994).

    Google Scholar 

  247. Sun, Q., Tsutsumi, K., Kelleher, M. B., Pater, A., And Pater, M. M., Squamous metaplasia of normal and carcinoma in situ of Hpv 16-immortalized human endocervical cells, Cancer Res. 52: 4254–4260 (1992).

    PubMed  CAS  Google Scholar 

  248. Sundberg, J. P., Papillomavirus infections in animals, in: Papillomaviruses and Human Disease, (K. Syrjanen, L. GIsSmann And L. Koss, EDs.), pp. 40–103, Springer-Verlag, Heidelberg, 1987.

    Google Scholar 

  249. Tabrizi, S. N., Tan, J., Quinn, M., Borg, A. J., And Garland, S. M., Detection of genital human papillomavirus (Hpv) Dna by Pcr and other conventional hybridisation techniques in male partners of women with abnormal Papanicolaou smears, Genitourin. Med. 68: 370–373 (1992).

    PubMed  CAS  Google Scholar 

  250. Tawa, K., Forsythe, A., Cove, K., Saltz, A., Peters, H., And Watring, W. G., A comparison of the Papanicolaou smear and the cervigram: Sensitivity, specificity, and cost analysis, Obstet. Gynecol. 71: 229–235 (1988).

    PubMed  CAS  Google Scholar 

  251. Tierney, R. J., Ellis, J. R. M., Winter, H., Kaur, S., Wilson, S., Woodman, C. B. J., And Young, L. S., Pcr for the detection of cervical Hpv16 infection: The need for standardization, Int. J. Cancer 54: 700–701 (1993).

    Article  PubMed  CAS  Google Scholar 

  252. Toll, Y., Kuwano, H., Tanaka, S., Baba, K., Matsuda, H., Sugimachi, K., And Mori, R., Detection of human papillomavirus Dna in esophageal carcinoma in Japan by polymerase chain reaction, Cancer 70 (9): 2234–2238 (1992).

    Article  Google Scholar 

  253. Tucker, R. A., Johnson, P. R., Reeves, W. C., And Icenogle, J. P., Using the polymerase chain reaction to genotype human papillomavirus Dnas in samples containing multiple Hpvs may produce inaccurate results, J. Virol. Methods 43: 321–334 (1993).

    Article  PubMed  CAS  Google Scholar 

  254. Van Den Brule, A. J. C., Walboomers, J. M. M., DU Maine, M., Kenemans, E, And Meuer, C. J. L. M., Difference in prevalence of human papillomavirus genotypes in cytomorphologically normal cervical smears is associated with a history of cervical intraepithelial neoplasia, Int. J. Cancer 48: 404–408 (1991).

    Article  Google Scholar 

  255. Van Doornum, G. J. J., Paws, M., JuFpermans, L. H. J., Hooykaas, C., Van Den Hoek, J. A. R., Coutinho, R. A., And Quint, W. G. V., Regional distribution and incidence of human papillomavirus infections among heterosexual men and women with multiple sexual partners; A prospective study, Genitourin. Med. 70 (4): 240–246 (1994).

    PubMed  Google Scholar 

  256. Van Ranst, M., Kaplan, J. B., And Burk, R. D., Phylogenetic classification of human papillomaviruses: Correlation with clinical manifestations, J. Gen. Virol. 73: 2653–2660 (1992).

    Article  PubMed  Google Scholar 

  257. Van Ranst, M. A., Tachezy, R., Delius, H., And Burk, R. D., Taxonomy of the human papillomaviruses, Papillomavirus Rep. 3: 61–65 (1993).

    Google Scholar 

  258. Vermund, S. H., Kelly, K. F., Klein, R. S., Feingold, A. R., Schreiber, K., Munk, G., And Burk, R. D., High risk of human papillomavirus infection and cervical squamous intraepithelial lesions among women with symptomatic human immunodeficiency virus infection, Am. J. Obstet. Gynecol. 165: 392–400 (1991).

    Article  PubMed  CAS  Google Scholar 

  259. Vermund, S. H., Schiffman, M. H., Goldberg, G. L., RrI IhR, D. B., Weltman, A., And Burk, R. D., Molecular diagnosis of genital human papillomavirus infection: Comparison of two methods used to collect exfoliated cervical cells, Am. J. Obstet. Gynecol. 160: 304–308 (1989).

    Article  PubMed  CAS  Google Scholar 

  260. Viscidi, R. P., Sun, Y., Tsuzaki, B., Bosch, E. X., Munoz, N., And Shah, K. V., Serologic response in human papillomavirus-associated invasive cervical cancer, Mt. J. Cancer 55: 780–784 (1993).

    CAS  Google Scholar 

  261. Wank, R., And Thomssen, C., High risk of squamous cell carcinoma of the cervix for women with Hla-DQw3, Nature 352: 723–725 (1991).

    Article  PubMed  CAS  Google Scholar 

  262. Werness, B. A., Munger, K., And Howley, R. M., Role of the human papillomavirus oncoproteins in transformation and carcinogenic progression, Important Adv. Oncol. 1991: 3–18 (1991).

    Google Scholar 

  263. Wheeler, C. M., Parmenter, C. A., Hunt, C., Becker, T. M., Greer, C. E., Hildesheim, A., And Manos, M. M., Determinants of genital human papillomavirus infection among cytologically normal women attending the University of New Mexico student health center, Sex. Transm. Dis. 20: 286–289 (1993).

    Article  PubMed  CAS  Google Scholar 

  264. Wideroff, L., Schiffman, M. H., Kirnbauer, R., Hubbert, N., Nonnemacher, B., Lowy, D., Lorincz, A. T., Manos, M. M., Glass, A. G., ScoTT, D. R., Sherman, M. E., Kurman, R. J., Buckland, J., Tarone, R. E., And Schiller, J., Validation of a serologic marker for persistent Hpv 16 infection, J. Infect. Dis. 172: 1425–1430 (1995).

    Article  PubMed  CAS  Google Scholar 

  265. Wiener, J. S., And Walther, P. J., A high association of oncogenic human papillomaviruses with carcinomas of the female urethra: Polymerase chain reaction-based analyses of multiple histological types, J. Urol. 151: 49–53 (1994).

    PubMed  CAS  Google Scholar 

  266. Wikstrom, A., Lidbrink, P., Johansson, B., And Von Krogh, G., Penile human papillomavirus carriage among men attending Swedish Std clinics, Int. J. Std Aids 2: 105–109 (1991).

    PubMed  CAS  Google Scholar 

  267. Williams, H. C., Pottier, A., And Strachan, D., The descriptive epidemiology of warts in British schoolchildren, Br. J. Dermatol. 128: 504–511 (1993).

    Article  PubMed  CAS  Google Scholar 

  268. Wright, T. C., Gagnon, S., Richart, R. M., And Ferenczy, A., Treatment of cervical intraepithelial neoplasia using the loop electrosurgical excision procedure, Obstet. Gynecol. 79: 173–178 (1992).

    PubMed  Google Scholar 

  269. XI, L. F., Demers, W., Kiviat, N. B., Kuypers, J., Beckmann, A. M., And Galloway, D. A., Sequence variation in the noncoding region of human papillomavirus type 16 detected by single-strand conformation polymorphism analysis, J. Infect. Dis. 168: 610–617 (1993).

    Article  PubMed  CAS  Google Scholar 

  270. Yeudall, W. A., Human papillomaviruses and oral neoplasia, Oral Oncol. Eur. J. Cancer 28B: 61–66 (1992).

    Google Scholar 

  271. Zur Hausen, H., Papillomaviruses in human cancer, Cancer 59: 1692–1696 (1987).

    Article  PubMed  Google Scholar 

  272. zUR Hausen, H., Viruses in human cancers, Science 254: 11671173 (1991).

    Google Scholar 

  273. Zur Hausen, H. (ED.), Current Topics in Microbiology and Immunology, Vol. 186, Human Pathogenic Papillomaviruses, Springer Verlag, Heidelberg, 1994.

    Google Scholar 

Suggested Reading

  • Iarc monographs on the evaluation of carcinogenic risks to humans, vol. 64: Human papillomaviruses. Iarc, Lyon, France, 1995.

    Google Scholar 

  • Munoz, N., Bosch, E. X., Shah, K. V., And Meheus, A., The Epidemiology of Human Papillomavirus and Cervical Cancer, No. 119, Iarc Scientific Publications, Lyon, 1992.

    Google Scholar 

  • Shah, K. V., And Howley, P. M., Papillomaviruses, in: Virology, 3rd ed. (B. N. Fields, D. M. Knipe, And P. M. Howley, Eds.), pp. 20772109, Raven Press, New York, 1995.

    Google Scholar 

  • Zur Hausen, H., Current Topics in Microbiology and Immunology, Vol. 186, Human Pathogenic Papillomaviruses, Springer-Verlag, Heidelberg, 1994.

    Book  Google Scholar 

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Authors and Affiliations

  1. Epidemiology and Biostatistics Program, National Cancer Institute, Bethesda, Maryland, 20892, USA

    Mark H. Schiffman

  2. Departments of Pediatrics, Microbiology, and Immunology and Obstetrics and Gynecology, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, 10461, USA

    Robert D. Burk

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  1. Department of Epidemiology and Public Health, Yale University School of Medicine, 06510, New Haven, Connecticut, USA

    Alfred S. Evans

  2. Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 35294-0008, Birmingham, Alabama, USA

    Richard A. Kaslow

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Schiffman, M.H., Burk, R.D. (1997). Human Papillomaviruses. In: Evans, A.S., Kaslow, R.A. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0036-4_33

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