Abstract
Cholesterol (cholest-5-en-3β-ol) (1), the chief sterol of mammalian tissues and obligate precursor of steroid hormones and bile salts, has received much attention to its chemistry and biochemistry, to its role in membrane integrity and function, and to its association with human diseases such as atherosclerosis, gallstones, and cancer. The relationships between cholesterol and human disorders have attracted interest for over two centuries and date from the work of Vallisneri [2545] in 1733 on the properties of human gallstones, from which cholesterol was ultimately isolated. An association between cholesterol deposits and human aortal plaque formation was well recognized by 1847 [2597], and several other relations of cholesterol to pathological states were summarized in 1862 [779].
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© 1981 Springer Science+Business Media New York
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Smith, L.L. (1981). Introduction. In: Cholesterol Autoxidation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9691-9_1
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DOI: https://doi.org/10.1007/978-1-4757-9691-9_1
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-9693-3
Online ISBN: 978-1-4757-9691-9
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