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Modulation by Polyunsaturated Lipid Diets of Nitrosamine-Induced Cancers in Rats: Effects on Prooxidant State and Drug Metabolism

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Abstract

Dietary lipids are associated with increased risks for certain types of cancer, especially those of the breast and colon. This enhancing effect has been documented in humans by epidemiological studies1,2,3, as well as by studies in experimental animals4,5,6,7,8. Although the association between dietary lipids and carcinogenesis has been known for a long time, the molecular mechanism by which lipids modulate tumor development remains largely unknown.

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Bartsch, H., Hietanen, E., Ahotupa, M., Camus, AM., Béréziat, JC. (1988). Modulation by Polyunsaturated Lipid Diets of Nitrosamine-Induced Cancers in Rats: Effects on Prooxidant State and Drug Metabolism. In: Feo, F., Pani, P., Columbano, A., Garcea, R. (eds) Chemical Carcinogenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9640-7_65

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  • DOI: https://doi.org/10.1007/978-1-4757-9640-7_65

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9642-1

  • Online ISBN: 978-1-4757-9640-7

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