Abstract
p-Boronophenylalanine (p-BPA)-fructose complex has been used for Boron Neutron Capture Therapy (BNCT) of malignant melanoma.1,2 o- and m-Boronophenylalanine (o- and m-BPA) are the isomers of p-BPA, and it is interesting to study the relationship between the chemical properties and incorporation of boron into malignant cells. We have already reported the synthesis of o-BPA and m-BPA.3 In this paper we will describe the chemical properties of these three structural isomers, and some biological uptake results.
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References
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© 1996 Springer Science+Business Media New York
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Yoshino, K. et al. (1996). Chemical Properties of p-, m-, o-Boronophenylalanine. In: Mishima, Y. (eds) Cancer Neutron Capture Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9567-7_10
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DOI: https://doi.org/10.1007/978-1-4757-9567-7_10
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-9569-1
Online ISBN: 978-1-4757-9567-7
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