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Antineoplastic Agents and Cancer Cell Differentiation

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Cancer Biology and Therapeutics

Abstract

Because specific approaches for the inhibition or modulation of the cancer cell are lacking, therapies are used that adversely affect some normal cells as well as tumor cells. These treatments make use of highly cytotoxic antibiotics such as daunomycin and actinomycin D, and of cytotoxic antimetabolites such as methotrexate and araC. The agents are employed at maximally tolerated doses in order to remove the greatest possible number of tumor cells.

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References

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© 1987 Springer Science+Business Media New York

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Bloch, A. (1987). Antineoplastic Agents and Cancer Cell Differentiation. In: Cory, J.G., Szentivanyi, A. (eds) Cancer Biology and Therapeutics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9564-6_15

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  • DOI: https://doi.org/10.1007/978-1-4757-9564-6_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9566-0

  • Online ISBN: 978-1-4757-9564-6

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