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Heterogeneity of Mononuclear Phagocytes

An Interpretive Review

  • Chapter
Macrophages and Related Cells

Part of the book series: Blood Cell Biochemistry ((BLBI,volume 5))

Abstract

In this chapter we would like to review evidence supporting the concept that there is extensive heterogeneity of mammalian mononuclear phagocytes. Given the limits of this chapter, we will summarize data supporting this notion rather than provide an in-depth review of particular characteristics and functions of these cells. Therefore, the main subjects will be the mononuclear phagocyte system as a whole and the heterogeneous features of the various members of the system expressed both phenotypically and functionally. Finally, we will discuss various models that may explain how mononuclear phagocyte heterogeneity is generated (see also Chapter 3, this volume).

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Leenen, P.J.M., Campbell, P.A. (1993). Heterogeneity of Mononuclear Phagocytes. In: Horton, M.A. (eds) Macrophages and Related Cells. Blood Cell Biochemistry, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9534-9_2

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