Abstract
After the discovery of penicillin, systematic programs to search for new antibiotics were initiated. These resulted, in a short time, in the discovery of thousands of active molecules and, most importantly, of a number of clinically useful agents. The basic concepts of these programs, usually termed screening programs, were established by Waksman at Rutgers State University in the early 1940s. They are still valid today and are applied in many academic and industrial research laboratories all over the world.
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Lancini, G., Lorenzetti, R. (1993). The Search for New Bioactive Microbial Metabolites. In: Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9522-6_3
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DOI: https://doi.org/10.1007/978-1-4757-9522-6_3
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