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Diagnosis and Treatment of Neurologic Disorders in AIDS and Other Sexually Transmitted Diseases

  • Chapter
Behavioral Aspects of AIDS

Abstract

This chapter provides an overview of the range of neurological problems that may develop in association with AIDS and other sexually transmitted diseases. The first section is devoted primarily to those occurring in acquired immune deficiency syndrome (AIDS), excluding the AIDS dementia complex. The second section is devoted to the diagnosis and treatment of neurological problems associated with other sexually transmitted diseases.

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References

  1. Johnson RT, McArthur JC: AIDS and the brain. Trends Neurosci 9: 91–94, 1986.

    Article  Google Scholar 

  2. Navia BA, Jordan BD, Price RW: The AIDS dementia complex: I. Clinical features. Ann Neurol 19: 517–524, 1986.

    Article  PubMed  Google Scholar 

  3. Navia BA, Cho E-S, Petito CK, et al: The AIDS dementia complex. II. Neuropathology. Ann Neurol 19: 525–535, 1986.

    Article  PubMed  Google Scholar 

  4. Cooper DA, Gold J, Maclean P, et al: Acute AIDS retrovirus infection: Definition of a clinical illness associated with seroconversion. Lancet 1: 537–540, 1985.

    Article  PubMed  Google Scholar 

  5. Ho DD, Rota TR, Schooley RT, et al: Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. New Engl J Med 313: 1493–1497, 1985.

    Article  PubMed  Google Scholar 

  6. Carne CA, Tedder RS, Smith A, et al: Acute encephalopathy coincident with seroconversion for antiHTLV-III. Lancet 2: 1206–1208, 1985.

    Article  PubMed  Google Scholar 

  7. McArthur JC, Farzadegan H, Cornblath DR, et al: Cerebrospinal fluid abnormalities in homosexual/bisexual men with and without neuropsychiatric symptoms, in Third International Conference on Acquired Immunodeficiency Syndrome (AIDS) June 1–5, 1987, Washington, DC (abst).

    Google Scholar 

  8. Goudsmit J, de Wolf F, Paul DA, et al: Expression of human immunodeficiency virus antigen (HIV-Ag) in serum and cerebrospinal fluid during acute and chronic infection. Lancet 2: 177–80, 1986.

    Article  PubMed  Google Scholar 

  9. McArthur JC, Sipos E, Chupp M, et al: Immunocytochemical staining of blood and cerebrospinal fluid mononuclear cells in AIDS-spectrum disorders. Neurology (NY) 37 (suppl 1): 319, 1987.

    Google Scholar 

  10. Black P: HIV, AIDS, and the brain. N Engl J Med 313: 1538–1539, 1985.

    Article  PubMed  Google Scholar 

  11. Nathanson N, Georgsson G, Palsson PA, et al: Experimental visna in Icelandic sheep: The prototype lentivirus infection. Rev Infect Dis 7: 75–82, 1985.

    Article  PubMed  Google Scholar 

  12. Petito CK, Navia BA, Cho E-S, et al: Vacuolar myelopathy pathologically resembling subacute combined degeneration in patients with the acquired immunodeficiency syndrome. N Engl J Med 312: 874–879, 1985.

    Article  PubMed  Google Scholar 

  13. Singh BM, Levine S, Yarrish RL, et al: Spinal cord syndromes in the acquired immune deficiency syndrome. Acta Neurol Scand 73: 590–598, 1986.

    Article  PubMed  Google Scholar 

  14. Goldstick L, Mandybur TI, Bode R: Spinal cord degeneration in AIDS. Neurology (NY) 35: 103–106, 1985.

    Article  Google Scholar 

  15. Rance N, McArthur J, Cornblath DR, et al: Gracile tract degeneration and sensory neuropathy in patients with AIDS. Neurology (NY) 38: 794–796, 1988.

    Article  Google Scholar 

  16. Spencer PS, Schaumburg HH: Central-peripheral distal axonopathy: The pathology of dying-back poly-neuropathies. Prog Neuropathol 3: 253–295, 1976.

    Google Scholar 

  17. Britton DB, Mesa-Tejada R, Fenoglio CM, et al: A new complication of AIDS: Thoracic myeltis caused by herpes simplex virus. Neurology (NY) 35: 1071–1074, 1985.

    Article  Google Scholar 

  18. Eidelberg D, Sotrel A, Vogel H, et al: Progressive polyradiculopathy in acquired immune deficiency syndrome. Neurology (NY) 36: 912–916, 1986.

    Article  Google Scholar 

  19. Tucker T, Dix RD, Katzen C, et al: Cytomegalovirus and herpes simplex virus ascending myelitis in a patient with acquired immune deficiency syndrome. Ann Neurol 18: 74–79, 1985.

    Article  PubMed  Google Scholar 

  20. Gessain A, Borin F, Vernant JC, et al: Antibodies to human T-lymphotropic virus type I in patients with tropical spastic paraparesis. Lancet 2: 407–409, 1985.

    Article  PubMed  Google Scholar 

  21. Osame M, Usuku K, Izumo S, et al: HTLV-I associated myelopathy, a new clinical entity. Lancet 1: 1031–1032, 1986.

    Article  PubMed  Google Scholar 

  22. Robert-Guroff M, Weiss SH, Giron JA, et al: Prevalence and antibodies to HTLV-I, -II, -III in intravenous drug abusers from an AIDS epidemic region. JAMA 255: 3133–3137, 1986.

    Article  PubMed  Google Scholar 

  23. Johnson RT, McArthur JC: Myelopathies and retroviruses. (Editorial.) Ann Neurol 21: 115–118, 1987.

    Article  Google Scholar 

  24. Jakobsen J, Trojaborg W, Helweg-Larsen S, et al: A Cross sectional population study of AIDS in Denmark: Neurological and electrophysiological report, in The Second International Meeting of the Peripheral Neuropathy Association on America, Hilton, South Carolina, November 4–8,1986. (abst).

    Google Scholar 

  25. Snider WD, Simpson DM, Nielson G, et al: Neurological complications of acquired immune deficiency syndrome: Analysis of 50 patients. Ann Neurol 14: 403–418, 1983.

    Article  PubMed  Google Scholar 

  26. Cornblath DR, McArthur JC, Kennedy PGE, et al: Inflammatory demyelinating peripheral neuropathies associated with human T-cell lymphotropic virus ype III infection. Ann Neurol 21: 32–40, 1987.

    Article  PubMed  Google Scholar 

  27. Fisher M: Residual neuropathological changes in Canadians held prisoners of war by the Japanese. Can Sery Med J 11: 159–199, 1955.

    Google Scholar 

  28. Spencer PS, Schaumburg HH (eds): Experimental and Clinical Neurotoxicology. Baltimore, Williams & Wilkins, 1980.

    Google Scholar 

  29. Yarchoan R, Brouwers P, Spitzer AR, et al: Response of human immunodeficiency-virus-associated neurological disease to 3’-azido-3’-deoxythymidine. Lancet 1:132–135, 1987.

    Google Scholar 

  30. Morris L, Distenfeld A, Amorosi E, et al: Autoimmune thrombocytopenic purpura in homosexual men. Ann Intern Med 96: 714–717, 1982.

    Article  PubMed  Google Scholar 

  31. Stricker RB, Abrams DI, Corash L, et al: Target platelet antigen in homosexual men with immune thrombocyopenia. N Engl J Med 313: 1375–1380, 1985.

    Article  PubMed  Google Scholar 

  32. Miller RG, Parry G, Lang W, et al: Aids-related inflammatory olyradiculoneuropathy: Prediction of response to plasma exchange with electrophysiologic testing. Muscle Nerve 8: 626, 1985.

    Article  Google Scholar 

  33. Mishra BB, Sommers W, Koski CK, et al: Acute inflammatory demyelinating polyneuropathy in the acquired immune deficiency syndrome. Ann Neurol 17: 131, 1985.

    Google Scholar 

  34. Cornblath DR, Griffin JW, Tennekoon G: CSF myelin basic protein in peripheral neuropathies. Ann Neurol 20: 370–372, 1986.

    Article  PubMed  Google Scholar 

  35. Kiprov DD, Abrams D, Pfaeffl W, et al: ARC/AIDS-related autoimmune syndromes and their treatment, in The Second International Conference on AIDS, Paris, June 1986 (abst).

    Google Scholar 

  36. Lipkin WI, Parry G, Kiprov D, et al: Inflammatory neuropathy in homosexual men with lymphadenopathy. Neurology (NY) 35: 1479–1483, 1985.

    Article  Google Scholar 

  37. Janssen RS, Saykin AJ, Kaplan JE, et al: Neurologic complications of lymphadenopathy syndrome associated with human immunodeficiency virus infection. Neurology (NY) 37 (suppl 1): 344, 1987.

    Google Scholar 

  38. Muder RR, Lumish RM, Corsello GR: Myelopathy after herpes zoster. Arch Neurol 40: 455–448, 1983.

    Article  Google Scholar 

  39. Watson PN, Evans RJ. Postherpetic neuralgia. Arch Neurol 43: 836–840, 1986.

    Article  PubMed  Google Scholar 

  40. Collaborative DHPG Treatment Study Group: Treatment of serious cytomegalovirus infections with 9-(1,3 Dihydroxy-2-propoxymethyl)guanine in patients with AIDS and other immunodeficiencies. N Engl J Med 314: 801–805, 1986.

    Article  Google Scholar 

  41. Levy RM, Bredesen DE, Rosenblum ML: Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): Experience at USCF and review of the literature. J Neurosurg 62: 475–495, 1985.

    Article  PubMed  Google Scholar 

  42. Coxon A, Pallis CA: Metronidazole neuropathy. J Neurol Neurosurg Psychiatry 39: 403–405, 1976.

    Article  PubMed  Google Scholar 

  43. Lhermitte F, Fritel D, Cambier J, et al: Polyneurites au cours de traitements par la nitrofurantione. Presse Med 71: 767, 1963.

    PubMed  Google Scholar 

  44. Navia BA, Petito CK, Gold JWM, et al: Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: Clinical and neuropathological findings in 27 patients. Ann Neurol 19: 224–238, 1986.

    Article  PubMed  Google Scholar 

  45. Elkin CM, Leon E, Grenell SL, et al: Intracranial lesions in the acquired immunodeficiency syndrome. JAMA 253: 393–396, 1985.

    Article  PubMed  Google Scholar 

  46. Levy RM, Mills CM, Posin JP, et al: The superiority of cranial magnetic resonance imaging (MRI) to computed tomographic (CT) brain scans for the diagnosis of cerebral lesions in patient with AIDS, in The Second International Conference on AIDS, Paris, June 1986 (abst).

    Google Scholar 

  47. Luft BJ, Brooks RG, Conley FK, et al: Toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome. JAMA 252: 913–917, 1984.

    Article  PubMed  Google Scholar 

  48. Kovacs JA, Kovacs AA, Polis M, et al: Cryptococcosis in the acquired immunodeficiency syndrome. Ann Intern Med 103: 533–538, 1985.

    Article  PubMed  Google Scholar 

  49. Miller JR, Barrett RD, Britton CB, et al: Progressive multifocal leukoencephalopathy in a male homosexual with T cell immune deficiency. N Engl J Med 307: 1436–1438, 1982.

    Article  PubMed  Google Scholar 

  50. Narayan O, Penney JB, Johnson RT, et al: Etiology of progressive multifocal leukoencephalopathy. Identification of papovavirus. N Engl J Med 289: 1278–1282, 1973.

    Article  PubMed  Google Scholar 

  51. Freeman WR, Lerner CW, Mines JA, et al: A prospective study of the ophthalmologic findings in the acquired immune deficiency syndrome. Am J Ophthalmol 97: 133–142, 1984.

    PubMed  Google Scholar 

  52. Holland GH, Pepose JS, Pettit TH, et al: Acquired immune deficiency syndrome: Ocular manifestations. Ophthalmology 90: 859–873, 1983.

    PubMed  Google Scholar 

  53. Khadem M, Kalish SB, Goldsmith J, et al: Ophthalmologic findings in acquired immune deficiency syndrome (AIDS). Arch Ophthalmol 102: 201–206, 1984.

    Article  PubMed  Google Scholar 

  54. Rosenberg PR, Uliss AE, Friedland GH, et al: Acquired immunodeficiency syndrome: Ophthalmic manifestations in ambulatory patients. Ophthalmology 90: 874–878, 1983.

    PubMed  Google Scholar 

  55. Newsome DA, Green WR, Miller ED, et al: Microvascular aspects of acquired immune deficiency syndrome retinopathy. Am J Ophthalmol 98: 590–601, 1984.

    PubMed  Google Scholar 

  56. Murray HW, Knox DL, Green WR, et al: Cytomegalovirus retinitis in adults: A manifestation of disseminated viral infection. Am J Med 63: 574–584, 1977.

    Article  PubMed  Google Scholar 

  57. Palestine AG, Stevens G Jr, Lane HC, et al: Treatment of cytomegalovirus retinitis with dihydroxy propoxymethyl guanine. Am J Ophthalmol 101: 95–101, 1986.

    PubMed  Google Scholar 

  58. Rosecan LR, Stahl-Bayliss CM, Kalman CM, et al: Antiviral therapy for cytomeglovirus retinitis in AIDS with dihydroxy propoxymethyl guanine. Am J Opthalmol 100: 405–418, 1986.

    Google Scholar 

  59. Holland GN, Sakamoto MJ, Hardy D, et al: Treatment of cytomegalovirus retinopathy in patients with acquired immunodeficiency syndrome. Arch Ophthalmol 104: 1794–1800, 1986.

    Article  PubMed  Google Scholar 

  60. Levy RM, Bredesen DE, Davis RL, et al: Multiple intracranial pathologies in the acquired immunodeficiency syndrome (AIDS): A report of 20 cases, in The Second International Conference on AIDS, Paris, June 1986. (abst).

    Google Scholar 

  61. Edwards RH, Messing R, McKendall RR: Cytomegalovirus meningoencephalitis in a homosexual man with Kaposi’s sarcoma. Neurology (NY) 35: 560–562, 1985.

    Google Scholar 

  62. Hawley DA, Schaefer JF, Schultz DM, et al: Cytomegalovirus encephalitis in acquired immunodeficiency syndrome. Am J Clin Pathol 80: 874–875, 1983.

    PubMed  Google Scholar 

  63. Pepose JS, Hilborne LH, Cancilla PA, et al: Concurrent herpes simplex and cytomegalovirus retinitis and encephalitis in the acquired immunodeficiency syndrome (AIDS). Ophthalmology 91: 1669–1670, 1984.

    PubMed  Google Scholar 

  64. Snider WD, Simpson DM, Aronyk KE, et al: Primary lymphoma of the nervous system associated with acquired immune-deficiency syndrome. N Engl J Med 308: 45, 1983.

    PubMed  Google Scholar 

  65. Hochberg EH, Miller G, Schooley RT, et al: Central nervous system lymphoma related to Epstein-Barr virus. N Engl J Med 309: 745–748, 1983.

    Article  PubMed  Google Scholar 

  66. Centers for Disease Control: Revision of the case definition of acquired immunodeficiency syndrome for national reporting-United States. MMWR 34: 373–374, 1985.

    Google Scholar 

  67. Hollander DH: Treponematosis from pinta to venereal syphilis revisited: Hypothesis for temperature determination of disease patterns. Sex Transm Dis 8: 34, 1981.

    Article  PubMed  Google Scholar 

  68. Fieldstal AH: Genetics of treponema, in Schell RF, Musher DF (eds): Pathogenesis and Immunology of Treponemal Infection. New York, Marcel Dekker, 1983, p 39.

    Google Scholar 

  69. Sexually Transmitted Disease Fact Sheet, ed 24. HEW Publication (CDC) 79–8195. Washington, DC, U.S. Department of Health, Education and Welfare, 1980.

    Google Scholar 

  70. Gjestland T: The Oslo study of untreated syphilis. Acta Derm Venereal (Stockh) 35 (suppl 34): 1–368, 1955.

    Google Scholar 

  71. Brown WJ: Status and control of syphilis in the United States. J Infect Dis 124 (4): 428–433, 1971.

    Article  Google Scholar 

  72. Turner TB: The race and sex distribution of the lesions of syphilis in 1000 cases. Bull Johns Hopkins Hasp 46: 159, 1930.

    Google Scholar 

  73. Schaudinn FR, Hoffman E: Vorlaufiger bericht uber das vorkommen von spirochaeten in syphilitischen krakheitsproducken und bei papillomen arbeien aus dem. K Gesundkeitsamte 22: 527, 1905.

    Google Scholar 

  74. Moore JE: The Modern Treatment of Syphilis, ed 2. Springfield, Illinois, Charles C Thomas, 1943.

    Google Scholar 

  75. Sparling PF: Diagnosis and treatment of syphilis. N Engl J Med 284: 642–653, 1971.

    Article  PubMed  Google Scholar 

  76. Simon RP: Neurosyphilis. Arch Neurol 42: 606–613, 1985.

    Article  PubMed  Google Scholar 

  77. Fiumara NJ: Serologic responses to treatment of 128 patients with late latent syphilis. Sex Transm Dis 6: 243–246, 1979.

    Article  PubMed  Google Scholar 

  78. Catterall RD: Systemic disease and the biological false positive reaction. Br J Vener Dis 48: 1–10, 1972.

    PubMed  Google Scholar 

  79. Tuffanelli DI: Aging and false positive reactions for syphilis. Br J Vener Dis 42: 40–41, 1966.

    PubMed  Google Scholar 

  80. Kaufman RE, Weiss S, Moore JD, et al: Biological false positive serological tests for syphilis among drug addicts. Br J Vener Dis 50: 350–353, 1974.

    PubMed  Google Scholar 

  81. Larsen SA, Hunter EF, McGrew BE: Syphilis, in Wentworth B, Judson FN (eds): Laboratory Methods for the Diagnosis of Sexually Transmitted Disease. Washington, DC, American Public Health Association, 1984.

    Google Scholar 

  82. Hamer RE, Smith JL, Israel CW. The FTA-ABS test in late syphilis: A serological study in 1985 cases. JAMA 203: 545–548, 1968.

    Article  Google Scholar 

  83. Larsen SA, Hambie EA, Peltidge DE, et al: Specificity, sensitivity and reproducibility among the fluorescent treponemal antibody absorption test, the microhemagglutination assay for treponema pallidum and the hemagglutination treponemal test for syphilis. J Clin Microbial 14: 441–445, 1981.

    Google Scholar 

  84. Larsen SA, Hambie EA, Wobig GH, et al: Cerebrospinal fluid test for syphilis, treponemal and nontreponemal tests, in Morreset R, et al (eds): Advances in Sexually Transmitted Diseases Utrecht, The Netherlands, VNU Science Press, 1985, pp 157–162.

    Google Scholar 

  85. Bracero L, Wormster GP, Boltone EJ: Serological tests for syphilis: A guide to interpretation in various stages of disease. Mt Sinai J Med (NY) 46: 289–292, 1979.

    Google Scholar 

  86. Criteria and techniques for the diagnosis of early syphilis. DHEW Publication 98–376. Atlanta, Centers for Disease Control, 1979.

    Google Scholar 

  87. Merritt HH, Adams RD, Solomon HC: Neurosyphilis. Oxford University Press, New York, 1946.

    Google Scholar 

  88. Vata K, Scheibel R, Keiffer et al: Neurosyphilis and diffuse cerebral angiopathy: A case report. Neurology (NY) 24: 472–476, 1974.

    Article  Google Scholar 

  89. Godt P, Stoeppler L, Wrischer U, et al: The value of computed tomography in cerebral syphilis. Neuroradiology 18: 197–200, 1979.

    Article  PubMed  Google Scholar 

  90. Fishman RA: Cerebrospinal Fluid in Diseases of the Nervous System. Philadelphia, WB Saunders Co, 1980, pp 225–285.

    Google Scholar 

  91. Merritt HH. A Textbook of Neurology. Philadelphia, Lea & Febiger, 1973.

    Google Scholar 

  92. Hotson JR: Modem neurosyphilis: A partially treated chronic meningitis (Medical Progress). West J Med 135: 191–200, 1981.

    PubMed  Google Scholar 

  93. Luxon L, Lees AJ, Greenwood RJ: Neurosyphilis today. Lancet 1: 90–93, 1979.

    Article  PubMed  Google Scholar 

  94. Fletcher WA, Sharpe JA: Tonic pupils in neurosyphilis. Neurology (NY) 36: 188–192, 1986.

    Article  Google Scholar 

  95. Jaffe HW, Robins SA: Cerebrospinal fluid examinations in patients with syphilis. Rev Infect Dis 4: 842–847, 1982.

    Article  Google Scholar 

  96. Mohr JA, Griffiths W, Jackson R. et al: Neurosyphilis and penicillin levels in cerebrospinal fluid. JAMA 236: 2208–2209, 1976.

    Article  PubMed  Google Scholar 

  97. Polnikorn N, Witoonpanich R, Varachit M, et al: Penicillin concentrations in cerebrospinal fluid after different treatment regimens for syphilis. Br J Vener Dis 56: 363–367, 1980.

    PubMed  Google Scholar 

  98. Tramont EC: Persistence of treponema pallidum following penicillin therapy. JAMA 236: 2206–2207, 1976.

    Article  PubMed  Google Scholar 

  99. Institute of Medicine. New Vaccine Development: Establishing Priorities. Vol 1: Diseases of Importance in the United States. Appendix 1. Prospects for immunizing against herpes simplex viruses. Report by a committee at the Institute of Medicine. Washington, DC, National Academy Press, 1985.

    Google Scholar 

  100. Dowdle WR, Nahmias AJ, Harwell RW et al: Association of antigenic type of herpes virus hominis with the site of virus recovery. J Immunol 99: 974–980, 1967.

    PubMed  Google Scholar 

  101. Hill TJ: Herpes simplex virus latency, in Roizman B (ed): The Herpes Virus, Vol 3. New York, Plenum Press 1985, pp 175–240.

    Chapter  Google Scholar 

  102. Corey L, Adams HG, Brown ZA, et al: Genital herpes simplex virus infections: Clinical manifestations, course, and complications. Ann Intern Med 98: 958–972, 1983.

    Article  PubMed  Google Scholar 

  103. Brenton DW: Hypoglycorrhachia in herpes simplex type 2 meningitis. Arch Neurol 37: 317, 1980.

    Article  PubMed  Google Scholar 

  104. Hemrika DJ, Schutte MF, Bleker OP: Eisberg syndrome: A neurologic basis for acute urinary retention in patients with genital herpes. Obstet Gynaecol 68 (3 suppl): 537–539, 1986.

    Google Scholar 

  105. Caplan LR, Kleeman FJ, Berg S: Urinary retention probably secondary to herpes genitalis. N Engl J Med 297: 920–921, 1977.

    Article  PubMed  Google Scholar 

  106. Goodell SE, Quinn TC, Mkrtichian E, et al: Herpes simplex proctitis in homosexual men: Clinical, sigmoidoscopic and histopathologic features. N Engl J. Med 308: 868–871, 1983.

    Article  PubMed  Google Scholar 

  107. Jacome DE, Yanez GF: Herpes genitalis and neurogenic bladder and bowel. J Urol 124: 752, 1980.

    PubMed  Google Scholar 

  108. Black D, Steward J, Melmed C: Sacral nerve dysfunction plus generalized polyneuropathy in herpes simplex genitalis. Ann Neurol 14: 692, 1983.

    Article  PubMed  Google Scholar 

  109. Handler CE, Perkin GD, Fray R, et al: Radiculomyelopathy associated with herpes simplex genitalis treated with adenosine arabinoside. Postgrad Med J 59: 388, 1983.

    Article  PubMed  Google Scholar 

  110. Klastersky J, Cappel R, Snoeck JM, et al: Ascending myelitis in association with herpes simplex virus. N Engl J Med 287: 182, 1972.

    Article  PubMed  Google Scholar 

  111. Corey L, Fife KH, Benedetti JK et al: Intravenous acyclovir for the treatment of primary genital herpes. Ann Intern Med 98: 914–921, 1983.

    Article  PubMed  Google Scholar 

  112. Bryson YJ, Dillon M, Lovett M, et al: Treatment of first episodes of genital herpes simplex virus infection with oral acyclovir: A randomized double blind control trial in normal subjects. N Engl J Med 308: 916–921, 1983.

    Article  PubMed  Google Scholar 

  113. Smith D: Gonococcal meningitis. Lancet 1: 1217, 1922.

    Article  Google Scholar 

  114. Rice RJ, Schalla WO, Wittington WL, et al: Phenotypic characterization of Neisseria gonorrhoeae isolated from three cases of meningitis. J Infect Dis 153: 362–365, 1986.

    Article  PubMed  Google Scholar 

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McArthur, J.C., Ashe, J., Jabs, D. (1990). Diagnosis and Treatment of Neurologic Disorders in AIDS and Other Sexually Transmitted Diseases. In: Ostrow, D.G. (eds) Behavioral Aspects of AIDS. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9386-4_12

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