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Scanning Force Microscopy on Living Virus-Infected Cells

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Atomic Force Microscopy/Scanning Tunneling Microscopy

Abstract

Using scanning force microscopy (SFM), it is possible to follow processes on the membrane of single living cells. Monkey kidney cells were imaged under normal growth conditions with a resolution of approximately 10 nm. Upon adding a suspension of pox virus, pronounced changes in the cell membrane were observed. Image sequences of these processes on the cell surface can be monitored over time. The cell membrane was studied to determine how it is affected by changes in temperature. The end of the micropipette holding the cell was also examined by SFM.

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© 1994 Springer Science+Business Media New York

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Häberle, W., Smith, D.P.E., Hörber, J.K.H., Czerny, C.P. (1994). Scanning Force Microscopy on Living Virus-Infected Cells. In: Cohen, S.H., Bray, M.T., Lightbody, M.L. (eds) Atomic Force Microscopy/Scanning Tunneling Microscopy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9322-2_2

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  • DOI: https://doi.org/10.1007/978-1-4757-9322-2_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9324-6

  • Online ISBN: 978-1-4757-9322-2

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