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Chemical Basis for Pharmacological and Therapeutic Actions of Penicillamine

  • Chapter
Protein Crosslinking

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 86))

Abstract

The pharmacological and therapeutic action of penicillamine are very largely explained by its ability to chelate metal ions and take part in oxidation-reduction reactions, sulfhydryldisulfide interchange, and nucleophilic addition. Effects of penicillamine on particular enzymes are explained by its chemical properties. Possible interactions with amino acids, tissue proteins, food constituents, and intermediates in the metabolism and biosynthesis of sulfur containing amino acids are discussed.

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  1. Western Regional Research Laboratory, Agricultural Research Service, U. S. Department of Agriculture, Berkeley, California, 94710, USA

    Mendel Friedman

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    Mendel Friedman

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Friedman, M. (1977). Chemical Basis for Pharmacological and Therapeutic Actions of Penicillamine. In: Friedman, M. (eds) Protein Crosslinking. Advances in Experimental Medicine and Biology, vol 86. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9113-6_36

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  • DOI: https://doi.org/10.1007/978-1-4757-9113-6_36

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9115-0

  • Online ISBN: 978-1-4757-9113-6

  • eBook Packages: Springer Book Archive

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