Abstract
The skeleton has two major functions: it provides structural support and acts as a mineral reservoir. It responds dynamically to hormones and mechanical stress, homeostatic factors that control serum calcium and skeletal architecture, geometry and bone mineral content. In providing structural support, the skeleton permits movement and protects vital organs. In its function as a mineral reservoir, it responds to changes in hormone levels and helps maintain serum calcium at about 9.8 mg/dL. Bone is resorbed to maintain serum calcium when dietary calcium is inadequate. If the dietary inadequacy is chronic, calcium will be pulled continually from the bone reservoir, resulting in a negative calcium balance and a net loss of calcium and phosphorus. Structural integrity therefore may be threatened when the demands on the reservoir to maintain serum calcium homeostasis are too high.
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Smith, E.L., Gilligan, C., Tommerup, L.J. (1994). Exercise and Bone Loss. In: Draper, H.H. (eds) Nutrition and Osteoporosis. Advances in Nutritional Research, vol 9. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9092-4_16
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DOI: https://doi.org/10.1007/978-1-4757-9092-4_16
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