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Adsorption on and Surface Chemistry of Hydroxyapatite pp 151–175Cite as

New NMR Methods for the Study of Hydroxyapatite Surfaces

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Abstract

Improved surface-characterization techniques are needed to study the adsorption of molecules and ions from aqueous solutions onto microcrystals of the biological mineral hydroxyapatite, the prime constituent of bone and teeth. The continuing development of techniques for obtaining high-resolution nuclear magnetic resonance (NMR) spectra from solids indicates that NMR could provide a valuable spectroscopic characterization of hydroxyapatite surfaces. We report here the successful application of new NMR techniques to two areas: (1) the adsorption onto the surface of hydroxyapatite of diphosphonates, used both as inhibitors of biological mineralization and as bone-scanning agents; (2) the reactions of hydroxyapatite with fluoride ion, which are important in the anti-caries benefits provided through fluoridation of dental enamel.

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Author information

Authors and Affiliations

  1. The Procter & Gamble Co., Cincinnati, Ohio, 45247, USA

    James P. Yesinowski

  2. Miami Valley Laboratories, Cincinnati, Ohio, 45247, USA

    Rex A. Wolfgang

  3. Sharon Woods Technical Center, Cincinnati, Ohio, 45247, USA

    Michael J. Mobley

Authors
  1. James P. Yesinowski
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  2. Rex A. Wolfgang
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  3. Michael J. Mobley
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Editor information

Editors and Affiliations

  1. Research Unit, National Bureau of Standards, America Dental Association Health Foundation, Washington, D.C., USA

    Dwarika N. Misra

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© 1984 Springer Science+Business Media New York

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Yesinowski, J.P., Wolfgang, R.A., Mobley, M.J. (1984). New NMR Methods for the Study of Hydroxyapatite Surfaces. In: Misra, D.N. (eds) Adsorption on and Surface Chemistry of Hydroxyapatite. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9012-2_10

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  • DOI: https://doi.org/10.1007/978-1-4757-9012-2_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9014-6

  • Online ISBN: 978-1-4757-9012-2

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