Abstract
According to a recent report of the World Health Organization,1 an estimated 21 million babies born throughout the world in 1979 were of “low birth weight” (2500 g or less). Low birth weight is often associated with brain underdevelopment and mental subnormality.2–4 Similar observations pertain to the early postnatal period.5
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References
World Health Organization. 1981, WHO Tech. Rep. Ser. 667: 7.
Wehmer, F., and Hafez, E. S. E., 1975, The Mammalian Fetus (E. S. E. Hafez, ed.), Charles C Thomas, Springfield, Illinois, pp. 154–185.
Scary, S., 1969, Social Biol. 16: 249–256.
Loehlin, J. C., Lindzey, G., and Spuhler, J. N.. 1975, Race Differences in Intelligence, W. H. Freeman, San Francisco, pp. 212–215.
Mönckeberg, F., Tisler, S. Toro, S., Gattàs, V., and Vega. L., 1972, Am. J. Clin. Nutr. 25: 766–772.
Naeye, R. L., Diener, M. M., Harcke, H. T., and Blanc, W. A., 1971. Pediatr. Res. 5:17–22
Klein, R. E., Arenales, P., Delgado, H., Engle, P. L., Guzman. G., Irwin. M., Lasky. R., Lechtig, A., Martorell, R., Mejia-Pivural, V., Russell, P., and Yarbrough, R.. 1976. Bull. Pan. Am. Health Org. 10: 301–316.
Committee on Maternal Nutrition, Food and Nutrition Board, National Research Council, 1970, Maternal Nutrition and the Course of Pregnancy, National Academy of Sciences, Washington.
Zamenhof, S., and van Marthens, E., 1974, Mol. Cell. Biochem. 4: 157–168.
Morgane, P. J., Miller, M., Kemper, T., Stern, W., Forbes, W.. Hall, R., Bronzino, J., Kissane, J., Hawrylewicz, E. J., and Resnick, 0., 1978, Neurosci. Behay. Rev. 2: 137–230.
Zamenhof, S.. and van Marthens, E., 1978, Studies of the Development of Behavior and the Nervous System, Volume 4, Early Influences (G. Gottlieb, ed.), Academic Press, New York, pp. 149–186.
Rosso, P.. and Cramoy, C., 1979, Human Nutrition, Volume, 1, Nutrition: Pre-and Postnatal Development (M. Winick, ed.). Plenum Press, New York, pp. 133–228.
Rozovski, S. J., and Winick, M., 1979, Human Nutrition, Volume 1, Nutrition: Pre-and Postnatal Development (M. Winick. ed.), Plenum Press, New York, pp. 61–102.
Zamenhof, S., 1979, Development and Evolution of Brain Size (M. E. Hahn, C. Jensen, and B. C. Dudek. eds.), Academic Press. New York, pp. 164–185.
Hurley, L. S., 1980. Developmental Nutrition, Prentice-Hall, Englewood Cliffs, New Jersey.
Williams, R. J., 1971, Proc. Natl. Acad. Sci. U.S.A. 68: 2899a.
Winick, M., and Noble, A., 1967, J. Nutr. 89: 179–182.
Hahn, M. E., Jensen, C., and Dudek, B. C. (eds.). 1979, Development and Evolution of Brain Size, Academic Press, New York.
Zamenhof. S., and van Marthens, E., 1982, Biol. Neonate 41: 68–73.
Clark, G. M., and Zamenhof, S.. 1973, Int. J. Neurosci. 5: 223–229.
Zamenhof, S., Grauel, L.. and van Marthens, E., 1971, Biol. Neonate 18: 140–145.
Zamenhof, S., Guthrie, D., and Clarkson, D.. 1974, Biol. Neonate 24: 354–362.
Zamenhof, S., and Holzman, G. B., 1973. Obstet. Gynecol. 41: 855–859.
Zamenhof, S., 1981, Anat. Rec. 199: 287A.
Varon, S. and Rainborn. C. W., Jr., 1969, Brain Res. 12: 180–199.
Johnson. H. A., and Erner, S., 1972, Exp. Gerontol. 7: 111–117.
Zamenhof, S., 1976. Brain Res. 109: 392–394.
Zamenhof, S., 1976, Wilhelm Roux’ Arch. 180: 1–8.
Zamenhof, S., and Klimuszko, D., 1977, Brain Res. 128: 385–388.
Vendrely, C., 1952, Bull. Biol. Fr. Belg. 86: 1–87.
Lapham, L. W., 1968, Science 159: 310–312.
Lentz, R. D., and Lapham, L. W., 1969, J. Neurochem. 16: 379–384.
Herman, C. J., and Lapham. L. W., 1969. Brain Res. 15: 35–48.
Zamenhof, S., Bursztyn, H. Rich, K., and Zamenhof, P. J., 1964, J. Neurochern. 11:505–509.
Zamenhof, S., van Marthens, E., Grauel, L., and Stillinger, R. A., 1972, J. Neurochem. 19: 61–68.
Leslie, I., 1955, The Nucleic Acids. Volume 2 (E. Chargaff and J. N. Davidson. eds.), Academic Press, New York, pp. 1–50.
Holloway, R. L., 1968. Brain Res. 7: 121–172.
Welker. W. I., Johnson, J. I.. and Pubols, B. H., 1964, Am. Zool. 4: 75–94.
Villescas, R., Zamenhof, S., and Guthrie, D., 1979, Phvsiol. Behay. 23: 945–954.
Clendinnen, B. G.. and Eayrs, J. T., 1961, J. Endocrinol. 22: 183–193.
Clark, G. M., Zamenhof. S., van Marthens, E., Grauel, L.. and Kruger, L., 1973, Brain Res. 54: 397–402.
Bass, N. H., 1984, Handbook of Neurochemistry,Volume 8 (A. Lajtha, ed.), Plenum Press, New York (in press).
Berry, M., 1974, Aspects of Neurogenesis (G. Gottlieb. ed.). Academic Press, New York, pp. 7–67.
Altman, J. 1971, Brain Development and Behavior (M. B. Sterman, D. J., McGinty, and A. M. Adinolfi, eds.), Academic Press, New York, pp. 359–368.
Altman, J., 1966, Exp. Neurol. 16: 263–278.
Zamenhof, S., van Marthens, E., and Margolis, F. L., 1968, Science 160: 322–323.
Zamenhof, S., Ahmad, G., and Guthrie, D.. 1979, Biol. Neonate 35: 273–278.
Dobbing, J., and Sands, J., 1970, Nature 226: 639–640.
Dubbing, J., and Sands, J., 1973, Arch. Dis. Child. 48: 757–767.
Chase, H. P., Welch, N. N., Dabiere. C. S., Vasan, N. S.. and Butterfield, L. J., 1972, Pediatrics 50: 403–411.
Altman, J. Das, G. D., and Sudarsham. K., 1970, Dev. Psychobiol. 3: 281–301.
Hammer, R. P., 1981. Dev. Brain Res. 1: 191–201.
Balazs, R., Lewis, P. D., and Patel, A. J., 1979, Human Growth. Volume 3, Neurobiology and Nutrition (F. Falkner and J. M. Tanner, eds.), Plenum Press. New York, pp. 415–480.
Davison, A. N.. and Dobbing, J., 1966, Br. Med. Bull. 22: 40–44.
Bass, N. H., Netsky, M. G., and Young, E., 1970, Arch. Neurol. 23: 303–313.
Wiggins, R. C., Miller, S. L., Benjamins. J. A., Krigman, R. M., and Morell, P., 1976, Brain Res. 107: 257–273.
Yusuf, H. K. M., Hague, Z. and Mozaffar. Z., 1981, J. Neu rochera. 36: 924–930.
Lederman, S. A. and Rosso P., 1980, Growth 44: 77–88.
Lederman, S. A.. and Rosso. P., 1981, J. Nurr. 111: 2162–2171.
Dobbing, J. (ed.), 1981, Maternal Nutrition in Pregnancy-Eating for Two? Academic Press, London.
Zamenhof, S., van Marthens, E., and Grauel, L., 1971, J. Nutr. 9: 1265–1269.
Rosso. P., 1975, Science 187: 648–650.
Rosso, P., and Streeter, M. R., 1979, J. Nutr. 109: 1887–1892.
Rosso. P., and Kava, R.. 1980, J. Nutr. 110: 2350–2354.
Ahokas, R. A.. Lahaye, E. B., Anderson. G. D., and Lipshitz. J., 1981, J. Nutr. 111: 2052–2058.
Usher. R. H. 1970, Pediatr. Clin. North Am, 17:169–183.
Sturman, J. A., Gault, G., and Raiha. N. C. R., 1970, Science 169: 74–76.
Vesalius, A., 1543, De Hunuani Corporis Fabrica, Officina Joannis Oporini, Basileae.
Alexander, D. P., Britton. H. G., Cohen, N. M., and Nixon, D. A.. 1969, Foetal Autonomy (G. E. W. Wolstenholme and M. O’Connor, eds.) Churchill, London, pp. 95–113.
Hahn, P.. 1979, Human Nutrition, Volume 1, Nutrition: Pre-and Postnatal Development (M. Winick, ed.), Plenum Press, New York, pp. 1–39.
Yarnell, G. R., Nelson, P. A., and Wagle, S. R., 1966, Fed. Proc. 25: 449.
Zamenhof, S., 1981, Biol. Neonate 39: 45–51.
McFarlane, L. G.. and von Holt, C., 1969, Biochern. J. 111: 557–563.
Yamashita, K., and Ashida, K., 1969, J. Nutr. 99: 267–273.
Dawes, G. M., 1968, Foetal and Neonatal Physiology, Year Book Medical Publishers, Chicago. pp. 213–219.
Minkowski, A., Roux, J. M.. and Tordet-Caridroit. C., 1974, Nutrition and Fetal Development (M. Winick, ed.). John Wiley and Sons, New York. pp. 45–78.
Sinclair, J. C., Saigal. S., and Yeung, C. Y., 1974, Nutrition and Fetal Development (M. Winick. ed.), John Wiley and Sons, New York. pp. 147–171.
Romsos, D. R., Palmer, H. J., Muiruri. K. L., and Bennink, M. R.. 1981, J. Nutr. 111:678–689.
Zamenhof. S., van Marthens, E., and Grauel, L., 1971. Science 174: 954–955.
Zamenhof, S., van Marthens, E., and Grauel. L., 1971. Nutr. Rep. Int. 4: 269–274.
Clark, G. M., Zamenhof, S., van Marthens. E.. Grauel. L.. and Kruger, L., 1973, Brain Res. 54: 397–402.
Siassi, F., and Siassi, B., 1973, J. Nutr. 103: 1625–1633.
Dancis, J., and Schneider, H., 1975, The Placenta (P. Gruenwald, ed.), University Park Press, Baltimore, pp. 97–124.
Clifford, A., 1980, Human Nutrition, Volume 3A. Nutrition an the Adult, (R. B. Alfin-Slater and D. Kritchevsky, eds.). Plenum Press, New York, pp. 183–211.
Gaul’, G. E., and Rassin, D. K., 1979, Neural Growth and Differentiation (E. Meisami and M. A. B. Brazier, eds.), Raven Press, New York. pp. 461–477.
Huxtable, R. J., and Pasantes-Morales, H., 1981. Taurine in Nutrition and Neurology. Plenum Press, New York.
Sturman, J. A., 1982, Dev. Brain Res. 2: 111–128.
Newburg, D. S., 1982, Fed. Proc. 41: 392.
Zamenhof. S., Hall, S. M., Grauel, L., van Marthens. E., and Donahue. M. J., 1974. J. Nutr. 104: 1002–1007.
Chase, H. P., and Jansen, G. R., 1976, J. Nutr. 106: 41–47.
Eisenstein, R. S., and Harper. A. E., 1981, Fed. Proc. 40: 326.
Metcoff. J., Cole, T. J., and Luff, R.. 1981. J. Nutr. 111: 1411–1424.
Miller, S. A., 1970, Fed. Proc. 29: 1497–1502.
Zamenhof, S., 1977, Research to Practice in Mental Retardation, Biomedical Aspects, Volume III (P. Mittler, ed.), University Park Press, Baltimore, pp. 346–354.
Lederman, S. A., and Rosso, P., 1981, J. Noir. 111: 1823–1832.
Johnson, E. M., 1965, Teratology (J. G. Wilson and J. Warkany, eds.), University of Chicago Press, Chicago. pp. 113–124.
Kalter, H., 1968, Teratology of the Central Nervous System, University of Chicago Press, Chicago.
Giroud, A., 1970, The Nutrition of the Embryo, Charles C Thomas. Springfield, Illinois.
Manocha, S. L., 1972. Malnutrition and Retarded Human Development, Charles C Thomas, Springfield, Illinois, pp. 27–37.
Dodge, P. R., Prensky, A. L., and Feigin, R. D., 1975, Nutrition and the Developing Nervous System, C. V. Mosby, St. Louis.
Takahashi, Y. I., Smith, J. E., Winick, M., and Goodman. D. S., 1975, J. Nutr. 105: 1299–1310.
Langman, J. and Welch, G. W., 1967, J. Comp. Neurol. 131: 15–26.
Kaminetzky, H. A.. Baker, H., Frank, O.. and Langer, A., 1974, Am. J. Obstet. Gynecol. 120: 697–703.
Hibbard, B. M., Hibbard, E. D., and Jeffcoate, T. N. A., 1965, Acta Obstet. Gynecol. Scand. 44: 375–400.
Hibbard, B. M., 1975, S. Afr. Med. J. 49: 1223–1226.
Kitay, D. Z., 1969, Am. J. Obstet. Gynecol. 104: 1067–1107.
Verma, K., and Wei King. D., 1967, Acta Anat. 67: 623–635.
Davis, S. D., Nelson, T., and Shepard, T. H., 1970, Science 160: 1329–1330.
Driskell, J. A., and Kirksey, A., 1971, J. Nutr. 101: 661–668.
Moon, W. H. Y., and Kirksey, A., 1972, J. Nutr. 102: 123–133.
Kurtz, D. J., Levy, H., and Kanfer, J. N., 1972, J. Nutr. 102: 291–298.
Williamson. B., and Coniglio. J. G., 1971, J. Neurochem. 18: 267–276.
Huber, A. M., and Gershoff, S., 1965, J. Nutr. 87: 407–411.
Chang, S. J., Kirksey, A., and Morré, D. M., 1981, J. Nutr. 111: 848–857.
Woodard, J. C., and Newberne, P. M., 1966, J. Nutr. 88: 375–381.
Newberne, P. M., Ahlstrom. A. and Rogers, A. E., 1970, J. Nutr. 100:1089–1098.
Newberne, P. M., 1963, Am. J. Vet. Res. 24: 1304–1312.
Newberne, P. M., and Young. V. R., 1973, Nature 242: 263–264.
Rosenthal, W. S., Tanaka. N., and Glass, G. B. J., 1969, Fed. Proc. 28: 627.
Svennerholm, L., Ailing, C., Bruce, A, Karlsson, I., and Sapia, O.. 1972, Lipids, Malnutrition and the Developing Brain (K. Elliott and J. Knight, eds.), Ciba Foundation Symposium, Elsevier, Amsterdam, pp. 141–157.
Sinclair, A. J., and Crawford, M. A., 1971, Proc. Biochem. Soc. 11: 18.
Steinberg. A. B., Clarke. G. B., and Ramwell. P. W., 1968, Dev. Psychobiol. 1: 225–229.
Berkow, S. E., and Campognoni, A. T., 1981, J. Nutr. 111: 886–894.
Leibel, R. L., Greenfield, D. B.. and Pollitt, E., 1979. Nutrition, Pre-and Postnatal Development (M. Winick, ed.), Plenum Press, New York, pp. 383–439.
Hoffbrand, A. V., Ganeshaguru. K., Hooton, J. W. L., and Tattersall. M. H. N., 1976, Br. J. Haematol. 33: 517–526.
Carlton, W. W., and Kelly. W. A., 1969, J. Nutr. 97: 42–52.
Everson, G. J., Shrader, R. E., and Wang. T., 1967, J. Nutr. 93: 533–540.
Hetzel, B. S., 1980, Endemic Goiter and Endemic Cretinism: Iodine Nutrition in Health and Disease (John B. Stanbury and B. S. Hetzel, eds.). John Wiley and Sons, New York.
Hetzel, B. S., and Smith, R. M., 1981, Fetal Brain Disorders: Recent Approaches to the Problem of Mental Deficiency, Elsevier, Amsterdam.
Cantin, M., and Seelig, M. S., 1980, Magnesium in Health and Disease. SP Medical and Scientific Books, New York, pp. 827–864.
Sauer, G., 1980, Chromium in Nutrition and Disease, Alan R. Liss, New York.
Hurley, L. S., 1976, Present Knowledge in Nutrition, 4th ed. ( D. M. Hegsted, ed.), The Nutrition Foundation, New York, pp. 345–355.
Apgar, J., 1968, Am. J. Physiol. 215: 160–163.
Caldwell, D. F., and Oberlas. D., 1969, Perinatal Factors Affecting Human Development, Pan American Health Organization. Washington, pp. 2–8.
Duncan, J. R., and Hurley, L. S., 1978, Proc. Soc. Exp. Biol. Med. 159: 39–43.
McKenzie, J. M., Fosmire, G. J., and Sanstead. H. H., 1975, J. Nutr. 105: 1466–1475.
Eckhert, C. D., and Hurley, L. S., 1977, J. Nutr. 107: 855–861.
Mertz, W., 1981, Science 213: 1332–1338.
Underwood, E. J., 1977, Trace Elements in Human and Animal Nutrition, Academic Press, New York.
Schwarz, K., 1974, Trace Element Metabolism in Animals, Volume 2, (W. G. Hoekstra, J. W. Suttie, H. E. Ganther, and W. Mertz, eds.), University Park Press. Baltimore, pp. 355–380.
Schwarz, K., 1970, J. Nutr. 100: 1487–1499.
Towbin, A., 1969, Science 164: 156–161.
Naeye, R. L., Blanc, W., and Paul, C., 1973. Pediatrics 52: 494–503.
Zamenhof. S., and van Marthens, E., 1978, J. Nutr. 108: 1719–1723.
Zamenhof, S., and van Marthens. E., 1982. Nutr. Rep. Internatl. 26: 703–709.
Zamenhof, S., Guthrie, D., and van Marthens, E.. 1976. Life Sci. 18: 1391–1396.
Zamenhof, S., 1941, Growth 5: 123–139.
Hunt, R. K., and Jacobson, M., 1970, Science 170: 342–344.
Zamenhof, S., 1942, Physiol. Zool. 15: 281–292.
Zamenhof, S., Mosley, J. and Schuller. E., 1966, Science 152: 1396–1397.
Sara, V. R., and Lazarus, L.. 1974, Nature 250: 257–258.
Sara, V. R., Lazarus, L.. Stuart, M. C., and King, T., 1974, Science 186: 446–447.
Sara, V. R., and Lazarus, V., 1975, Dev. Psychobiol. 8: 489–502.
Block. J. B., and Essman, W. B., 1965, Nature 205: 1136–1137.
Ray. O. S., and Hochhauser, S., 1969, Dev. Psychobiol. 1: 311–317.
Croskerry, P. G.. and Smith. G. K., 1975. Science 189: 648–650.
Zamenhof. S., and Ahmad, G., 1979. Growth 43: 160–166.
Harrison, M. R., Golbus, M. S., and Filly. R., 1981, J.A.M.A. 246: 774–777.
van Marthens, E., and Zamenhof, S.. 1969, Exp. Neurol. 23: 214–219.
Milkovic. K., Paunovic, J., and Joffe. J. M., 1976, Dev. Psychobiol. 9: 365–375.
Wehmer, F., and Jen, K. L. C., 1978, Dev. Psychobiol. 11: 353–360.
van Marthens, E., Grauel, L., and Zamenhof, S., 1972, Life Sci. 11: 1021–1029.
van Marthens, E., Grauel, L., and Zamenhof. S., 1974. Biol. Neonate 25: 53–56.
Croskerry, P. G., Smith. G. K.. Hall, S., and Shepard, B. J., 1978, Biol. Neonate 33: 31–38.
Zamenhof, S., and van Marthens, E., 1971, Cellular Aspects of Neural Growth and Differentiation (D. C. Pease, ed.), University of California Press, Berkeley, pp. 329–359.
Zamenhof, S., van Marthens, E., and Grauel, L.. 1972. Regulation of Organ and Tissue Growth (R. J. Goss, ed.). Academic Press. New York, pp. 41–60.
Widdowson, E. M., 1968, Biology of Gestation, Volume 2 (N. S. Assali, ed.). Academic Press, New York, pp. 1–49.
Zamenhof, S., and Guthrie, D., 1977, Biol. Neonate 32: 205–210.
Zamenhof, S., and van Marthens, E., 1982. Dev. Brain Res. 3: 657–661.
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Zamenhof, S. (1985). Malnutrition and Brain Development. In: Lajtha, A. (eds) Alterations of Metabolites in the Nervous System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6740-7_6
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