Abstract
The first well documented randomised controlled trial of medical treatment may have been that organised by the Medical Research Council and reported in 1948 [3]. However, Rose and Armitage have described a possible RCT dating from 1662 [5] and R.A. Fisher introduced randomised trials into agricultural research in 1920.
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© 1983 Springer Science+Business Media Dordrecht
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Bulpitt, C.J. (1983). The History of Controlled Trials. In: Randomised Controlled Clinical Trials. Developments in Biostatistics and Epidemiology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6358-4_2
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DOI: https://doi.org/10.1007/978-1-4757-6358-4_2
Publisher Name: Springer, Boston, MA
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