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Part of the book series: Lasers, Photonics, and Electro-Optics ((LPEO))

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Abstract

Laser balloon angioplasty (LBA) is presented as an example of a potential therapy based on thermal alterations of tissue by laser. Its future acceptance as a full clinical modality depends significantly on how its efficacy, advantages, and limitations compare with the current alternative angioplasty techniques described in Section 24.2. To guide its evaluation, discussions have been included which cover the LBA concept (Section 24.3), thermal welding of tissue (Section 24.4), catheter development and usage (Section 24.5), treatment goals (Section 24.6), laser dosimetry using simulation models (Section 24.7), and both acute and long-term tissue responses (Section 24.8). The LBA story reminds us that an engineered device and its implementation may be superb, but its intended application can be limited because of unfavorable biological reactions. In the case of LBA, the deterrent is the long-term restenosis following excellent acute enlargement of the vessel lumen.

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Cheong, WF., Crilly, R.J., Spears, J.R. (1995). Laser Balloon Angioplasty. In: Welch, A.J., Van Gemert, M.J.C. (eds) Optical-Thermal Response of Laser-Irradiated Tissue. Lasers, Photonics, and Electro-Optics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6092-7_24

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