Abstract
Using artificial, semi-permeable membranes, transplanted tissue can be physically isolated from the immune system of the recipient (immunoisolation). This allows, in principle, transplantation of cells of different genera, without the need for pharmacological immunosuppression (Clayton et al., 1993; Colton, 1995; Lanza & Chick, 1997). In the past, a whole range of different concepts have been employed to achieve this goal (see Clayton et al., 1993; Colton, 1995; Geisen et al., 1990; Lanza & Chick, 1997). It is now generally accepted that micocapsules composed of natuaral polysacccharides, especially of alginates, are the material of choice (Clayton et al., 1993; Geisen et al., 1990; Lanza & Chick, 1997; Smidsrod & Skjak-Braerk, 1990).
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Klöck, G., Gröhn, P., Hasse, C., Zimmermann, U. (1998). Biocompatible Alginates for Use in Biohybrid Organs. In: Gal, Y.L., Halvorson, H.O. (eds) New Developments in Marine Biotechnology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5983-9_12
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DOI: https://doi.org/10.1007/978-1-4757-5983-9_12
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