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A Review of Mass Spectrometric Techniques in the Structural Analysis of Native and Derivatized Gangliosides

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Gangliosides and Neuronal Plasticity

Part of the book series: FIDIA Research Series ((FIDIA,volume 6))

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Abstract

Mass spectrometry is especially qualified as an analytical tool because of its very high sensitivity and because of the abundant information provided on structural features of the analyte even if it is present only in minute quantities. Today, its application to the analysis of trace amounts of material is practically indispensable in biological and medical sciences (Burlingame, 1985).

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Abbreviations

MS:

mass spectronmetry

EI:

electron impact

FD:

field description

CI:

chenical ionization

SI:

secondary ion

FAB:

fast atom bombardment

DCI:

direct chemical ionzation

TMS:

trimethylsilyl

Neu5Ac, or NeuAc:

N-acethlNeuramicin acid

Neu5Gc, or NeuGc:

N-glycolylneuramicin acid

a.m.u.:

arbitrary mass units.

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Author information

Authors and Affiliations

  1. Institut für Physiologische Chemie, Universität Bonn, Nussallee 11, 5300, Bonn, Federal Republic of Germany

    H. Egge & J. Peter-Katalinić

Authors
  1. H. Egge
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  2. J. Peter-Katalinić
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Editor information

Editors and Affiliations

  1. Dipartimento di Chimica e Biochimica Medica, Facoltà di Medicina e Chirurgia, Università di Milano, Milano, Italy

    Guido Tettamanti

  2. Dept of Neurology and Biochemistry, Albert Einstein College of Medicine, Bronx, New York, USA

    Robert W. Ledeen

  3. Institut für Organische, Chemie und Biochemie, Universität Bonn, Bonn, Germany

    Konrad Sandhoff

  4. Dept of Biochemistry, University of Tokyo, Tokyo, Japan

    Yoshitaka Nagai

  5. Dept of Neurobiology, Brain Research Institute, Niigata University, Niigata, Japan

    Yoshitaka Nagai

  6. Research Laboratories, Fidia Neurobiological, Abano Terme, Italy

    Gino Toffano

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© 1986 Springer-Verlag Berlin Heidelberg

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Egge, H., Peter-Katalinić, J. (1986). A Review of Mass Spectrometric Techniques in the Structural Analysis of Native and Derivatized Gangliosides. In: Tettamanti, G., Ledeen, R.W., Sandhoff, K., Nagai, Y., Toffano, G. (eds) Gangliosides and Neuronal Plasticity. FIDIA Research Series, vol 6. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-5309-7_1

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  • DOI: https://doi.org/10.1007/978-1-4757-5309-7_1

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-5311-0

  • Online ISBN: 978-1-4757-5309-7

  • eBook Packages: Springer Book Archive

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