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Animal Models of Bipolar Disorder: From a Single Episode to Progressive Cycling Models

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Book cover Contemporary Issues in Modeling Psychopathology

Part of the book series: Neurobiological Foundation of Aberrant Behaviors ((NFAB,volume 1))

Abstract

Animal models of psychopathology are divided into three major groups: heuristic models that assume a common underlying mechanism between a superficially different animal behavior and a particular human pathology; theory-based evidential models, which place emphasis on a common feature (etiological or behavioral) of both the model and the pathology; representative models involving generalization of a well-validated behavior to model the pathology (Overmier and Patterson, 1988; Ursin and Murison, 1986). The choice of a particular model for research will depend ultimately on the extent to which the etiology of the disorder is known, the specificity and efficacy of the pharmacological treatments available, and the facility with which the pathological behaviors can be mimicked in laboratory animals.

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Authors
  1. Haim Einat
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  2. Ora Kofman
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  3. Robert H. Belmaker
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Editor information

Editors and Affiliations

  1. Psychobiology Research Unit, Department of Psychology, Tel Aviv University, 69978, Tel-Aviv, Israel

    Michael S. Myslobodsky

  2. Howard University, USA

    Michael S. Myslobodsky

  3. Department of Psychology, Tel Aviv University, 69978, Tel-Aviv, Israel

    Ina Weiner

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Einat, H., Kofman, O., Belmaker, R.H. (2000). Animal Models of Bipolar Disorder: From a Single Episode to Progressive Cycling Models. In: Myslobodsky, M.S., Weiner, I. (eds) Contemporary Issues in Modeling Psychopathology. Neurobiological Foundation of Aberrant Behaviors, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4860-4_10

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  • DOI: https://doi.org/10.1007/978-1-4757-4860-4_10

  • Publisher Name: Springer, Boston, MA

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