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Advances in Cardiovascular Engineering pp 25–40Cite as

Concentration and Velocity Profiles of Blood Cells in the Microcirculation

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Part of the book series: NATO ASI Series ((NSSA,volume 235))

Abstract

Although this chapter basically deals with the concentration and velocity profiles of blood cells in general, most of the data presented concern blood platelets. These small blood cells, with a density close to that of blood plasma, can be nicely used as natural markers of flow by fluorescently labeling them in vivo allowing their localization and the assessment of blood flow velocities at various sites in microvessels. Because of their role in hemostasis, thrombosis, and maintaining endothelial cell integrity, blood platelets can be expected to come in contact with the vessel wall. Recent in vivo studies have shown that blood platelets indeed do come close to the wall in arterioles(1,2), but less so in venules. In the latter microvessels a relatively large zone near the vessel wall from which blood platelets seem to be expelled, has to be appreciated(2).

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Author information

Authors and Affiliations

  1. Departments of Physiology and Biophysics Cardiovascular Research Institute Maastricht, University of Limburg, Maastricht, The Netherlands

    Robert S. Reneman, Bea Woldhuis, Mirjam G. A. oude Egbrink, Dick W. Slaaf & Geert Jan Tangelder

Authors
  1. Robert S. Reneman
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  2. Bea Woldhuis
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  3. Mirjam G. A. oude Egbrink
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  4. Dick W. Slaaf
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  5. Geert Jan Tangelder
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Editor information

Editors and Affiliations

  1. University of Miami, Coral Gables, Florida, USA

    Ned H. C. Hwang

  2. Department of Biomedical Engineering, Memphis State University, Memphis, Tennessee, 38152, USA

    Vincent T. Turitto  & Michael R. T. Yen  & 

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© 1992 Springer Science+Business Media New York

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Reneman, R.S., Woldhuis, B., oude Egbrink, M.G.A., Slaaf, D.W., Tangelder, G.J. (1992). Concentration and Velocity Profiles of Blood Cells in the Microcirculation. In: Hwang, N.H.C., Turitto, V.T., Yen, M.R.T. (eds) Advances in Cardiovascular Engineering. NATO ASI Series, vol 235. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4421-7_3

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  • DOI: https://doi.org/10.1007/978-1-4757-4421-7_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-3228-0

  • Online ISBN: 978-1-4757-4421-7

  • eBook Packages: Springer Book Archive

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