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Limitations of Nontransplant Treatment Options for Type 1 Diabetes Mellitus

  • Chapter
Transplantation of the Pancreas

Abstract

For decades clinicians have recognized that elevations in blood glucose are clearly associated with an increased risk of microvascular complications of diabetes—including retinopathy, nephropathy, and neuropathy. Prior to 1993, however, no intervention trial had successfully demonstrated that intensive treatment of blood glucose could significantly reduce the risk of these complications. With the publication of the landmark Diabetes Control and Complications Trial (DCCT) in 1993,1 it was confirmed that intensive therapy could indeed reduce the risk of the secondary complications, and intensive therapy has subsequently become the standard of care for virtually all patients with type 1 diabetes.

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Authors
  1. David M. Kendall
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  2. Richard M. Bergenstal
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Editor information

Editors and Affiliations

  1. Department of Surgery, University of Minnesota, 55455, Minneapolis, Minnesota, USA

    Rainer W. G. Gruessner MD (Professor) & David E. R. Sutherland MD, PhD (Professor) (Professor) &  (Professor)

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Kendall, D.M., Bergenstal, R.M. (2004). Limitations of Nontransplant Treatment Options for Type 1 Diabetes Mellitus. In: Gruessner, R.W.G., Sutherland, D.E.R. (eds) Transplantation of the Pancreas. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4371-5_3

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  • DOI: https://doi.org/10.1007/978-1-4757-4371-5_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-1830-7

  • Online ISBN: 978-1-4757-4371-5

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