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In Vitro Tests

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Fundamentals of Nuclear Pharmacy

Abstract

The radioimmunoassay (RIA) method was first developed by S. A. Berson and R. S. Yallow in the late 1950s for the determination of insulin in human serum. Presently, the method is employed extensively to determine numerous hormones, enzymes, and drugs in minute quantities (10-9–10-12 M) in human plasma in order to assess various disease conditions. The general term for this method in both immune and nonimmune systems is the competitive binding assay (CBA).

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Suggested Reading

  • Andrews JT, Milne MJ (1977) Nuclear medicine. Wiley, New York

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  • Kirkham KD, Hunter WM (1971) Radioimmunoassay methods. Williams & Wilkins, Baltimore

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  • Moss AJ Jr, Dalrymple GV, Boyd CM (eds) (1976) Practical radioimmunoassay. Mosby, St Louis

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  • Odell WD, Daughaday WH (eds) (1974) Principles of competitive protein-binding assays. Lippincott, Philadelphia

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  • Rothfeld B (ed) (1974) Nuclear medicine in vitro. Lippincott, Philadelphia

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  • Thorell JI, Larson SM (1978) Radioimmunoassay and related techniques. Mosby, St Louis

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  • Wagner HN (ed) (1968) Principles of nuclear medicine. Saunders, Philadelphia

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Author information

Authors and Affiliations

  1. University of Arkansas for Medical Sciences, Little Rock, Arkansas, 72201, USA

    Gopal B. Saha Ph.D. (Associate Professor of Radiology (Nuclear Medicine) and Pharmacy, Director of Radiopharmaceutical Program (Nuclear Medicine)

Authors
  1. Gopal B. Saha Ph.D.
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© 1979 Springer Science+Business Media New York

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Saha, G.B. (1979). In Vitro Tests. In: Fundamentals of Nuclear Pharmacy. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4021-9_11

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  • DOI: https://doi.org/10.1007/978-1-4757-4021-9_11

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-4023-3

  • Online ISBN: 978-1-4757-4021-9

  • eBook Packages: Springer Book Archive

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