Abstract
This chapter presents the lymphoreticular diseases affecting the lung, including primary and secondary lymphomas, leukemias, and a number of lesions that are generally considered benign and hyperplastic processes of lymphoid tissue. Many of these lesions, including pseudolymphoma and lymphocytic interstitial pneumonia, well-differentiated lymphocytic lymphomas of the lung, and lymphomatoid granulomatosis have been difficult for pathologists to classify.1–5 Lymphomatoid granulomatosis, with its synonyms,6,7 has been considered by some to be a peculiar vasculitis and by others a lymphoproliferative disorder.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Liebow AA, Carrington CB. Diffuse pulmonary lymphoreticular infiltrations associated with dysproteinemia. Med Clin North Am 1973; 57: 809 – 843.
Saltzstein SL. Extranodal malignant lymphomas and pseudolymphomas. Pathol Annu 1969; 4: 159 – 184.
Greenberg SD, Heisler JG, Gyorkey F, Jenkins DE. Pulmonary lymphoma vesus pseudolymphoma: a perplexing problem. South Med J 1972; 65: 775 – 784.
Julsrud PR, Brown LR, Li CY, Rosenow EC, Crowe JK. Pulmonary processes of mature-appearing lymphocytes: pseudolymphoma, well differentiated lymphocytic lymphoma, and lymphocytic interstitial pneumonitis. Radiology 1978; 127: 289 – 296.
Liebow AA, Carrington CB, Friedman PJ. Lymphomatoid granulomatosis. Hum Pathol 1972; 3: 457 – 558.
DeRemee RA, Weiland LH, McDonald TJ. Polymorphic reticulosis, lymphomatoid granulomatosis. Two diseases or one? Mayo Clin Proc 1978; 53: 634 – 640.
Saldana MJ, Patchefsky AS, Israel HI, Atkinson GW. Pulmonary angiitis and granulomatosis. Hum Pathol 1977; 8: 391 – 409.
Berard CW, Greene MH, Jaffe ES, Magrath I, Ziegler J. A multidiciplinary approach to non-Hodgkin’s lymphomas. Ann Intern Med 1981; 94: 218 – 235.
Nagaishi C. Functional anatomy and histology of the lung. Baltimore: University Park, 1972.
Kradin RL, Spirn PW, Mark EJ. Intrapulmonary lymph nodes. Chest 1985; 87: 662 – 667.
Bienenstock J, Johnston N, Perey DYE. Bronchial lymphoid tissue. I. Morphologic characteristics. Lab Invest 1973; 28: 686 – 692.
Bienenstock J, Johnston N, Perey DYE. Bronchial lymphoid tissue. II. Functional characteristics. Lab Invest 1973; 28: 693 – 698.
Bienenstock J, Befus AD. Gut-and bronchus-associated lymphoid tissue. Am J Anat 1984; 170: 437 – 445.
Isaacson P, Wright DH. Malignant lymphoma of mucosa-associated lymphoid tissue. Cancer 1983; 52: 1410 – 1416.
Isaacson P, Wright DH. Extranodal malignant lymphoma arising from mucosa-associated lymphoid tissue. Cancer 1984; 53: 2515 – 2524.
Hernandez JA, Sheehan WW. Lymphomas of the mucosa-associated lymphoid tissue. Cancer 1985; 55: 592 – 597.
Morris H, Edwards J, Tiltman A, Emms M. Endometrial lymphoid tissue: an immunohistological study. J Clin Pathol 1985; 38: 644 – 652.
Bragg DG. The clinical, pathologic and radiologic spectrum of the intrathoracic lymphomas. Invest Radiol 1978; 13: 2 – 11.
Balikian JP, Herman PG. Non-Hodgkin’s lymphoma of the lungs. Radiology 1979; 132: 569 – 576.
Blank N, Castellino RA. The intrathoracic manifestations of the malignant lymphomas and the leukemias. Semin Roentgenol 1980; 15: 227 – 245.
Yousem SA, Colby TV, Carrington CB. Follicular bronchitis/bronchiolitis. Hum Pathol 1985; 16: 700 – 706.
Meuwissen HJ, Hussain M. Bronchus-associated lymphoid tissue in human lung: correlation of hyperplasia with chronic pulmonary disease. Clin Immunol Immunopathol 1982; 23: 548 – 561.
Yousem SA, Colby TV, Carrington CB. Lung biopsy in rheumatoid arthritis. Am Rev Respir Dis 1985; 131: 770 – 777.
Dorfman RF, Warnke RA. Lymphadenopathy simulating malignant lymphomas. Hum Pathol 1974; 5: 519 – 550.
Frizzera G, Moran EM, Rappaport H. Angioimmunoblastic lymphadenopathy with dysproteinemia. Am J Med 1975; 59: 803 – 818.
Watanabe S, Shimosato Y, Shimoyama M. Lymphoma and leukemia of T-lymphocytes. Pathol Annu 1981; 16 (part 2): 155 – 204.
Iseman MD, Schwarz MI, Stanford RE. Interstitial pneumonia in angioimmunoblastic lymphadenopathy with dysproteinemia. Ann Intern Med 1976; 85: 752 – 755.
Zylak CJ, Banerjee R, Galbraith PA, McCarthy DS. Lung involvement in angioimmunoblastic lymphadenopathy. Radiology 1976; 121: 513 – 519.
Weisenburger D, Armitage L, Dick F. Immunoblastic lymphadenopathy with pulmonary infiltrates, hypocomplementemia and vasculitis. Am J Med 1977; 63: 849 – 854.
Strimlan CV, Rosenow EC III, Weiland LH, Brown LR. Lymphocytic interstitial pneumonitis. Ann Intern Med 1978; 88: 616 – 621.
Kradin RL, Mark EJ. Benign lymphoid disorders of the lung, with a theory regarding their development. Hum Pathol 1983; 14: 857 – 867.
Church, JA, Isaacs H, Saxon A, Keens TG, Richards W. Lymphoid interstitial pneumonitis and hypogammaglobulinemia in children. Am Rev Respir Dis 1981; 124: 491 – 496.
Dukes RJ, Rosenow EC, Hermans PE. Pulmonary manifestations of hypogammaglobulinemia. Thorax 1978; 33: 603 – 607.
Yoshizawa Y, Ohdama S, Ikeda A, Ohtsuka M, Masuda S, Tanaka M. Lymphoid interstitial pneumonia associated with depressed cellular immunity and polyclonal gammopathy. Am Rev Respir Dis 1984; 130: 507 – 509.
Solal-Celigny P, Couderc LJ, Herman D, et al. Lymphoid interstitial pneumonitis in acquired immunodeficiency syndrome-related complex. Am Rev Respir Dis 1985; 956 – 960.
Colby TV, Carrington CB. Lymphoreticular tumors and infiltrates of the lung. Pathol Annu 1983; 18: 27 – 70.
Turner RR, Colby TV, Doggett RS. Well-differentiated lymphocytic lymphoma: a study of 47 cases with primary manifestation of the lung. Cancer 1984; 54: 2088 – 2096.
Kohler PF, Cook RD, Brown WR, Manguso RL. Common variable hypogammaglobulinemia with T-cell nodular lymphoid interstitial pneumonitis and B-cell nodular lymphoid hyperplasia: different lymphocyte populations with a similar response to prednisone therapy. J Allergy Clin Immunol 1982; 70: 299 – 305.
Koss MN, Hochholzer L, Nichols PW, Wehunt WD, Lazarus AA. Primary non-Hodgkin’s lymphoma and pseudo-lymphoma of the lung: a study of 161 patients. Hum Pathol 1983; 14: 1024 – 1038.
Weiss LM, Yousem SA, Warnke RA. Non-Hodgkin’s lymphomas of the lung. Am J Surg Pathol 1985; 9: 480 – 490.
L’Hoste RJ, Filippa DA, Lieberman PH, Bretsky S. Primary pulmonary lymphomas. Cancer 1984; 54: 1397–1406.
Herbert A, Wright DH, Isaacson PG. Primary malignant lymphoma of the lung: histopathologic and immunologic evaluation of nine cases. Hum Pathol 1984; 15: 415 – 422.
Kennedy JL, Nathwani BN, Burke JS, Hill LR, Rappaport H. Pulmonary lymphomas and other lymphoid lesions. Cancer 1985; 56: 539 – 552.
Saltzstein SL. Pulmonary malignant lymphomas and pseudolymphomas: classification, therapy and prognosis. Cancer 1963; 16: 928 – 955.
Nathwani BN. A critical analysis of the classification of non-Hodgkin’s lymphomas. Cancer 1979; 44: 347 – 384.
Papaioannou AN, Watson WL. Primary lymphoma of the lung: an appraisal of its natural history and a comparison with other localized lymphoma. J Thorac Cardiovasc Surg 1965; 47: 373 – 387.
Colby TV, Carrington CB. Malignant lymphoma simulating lymphomatoid granulomatosis. Am J Surg Pathol 1982; 6: 19 – 32.
Essig LJ, Timms ES, Hancock DE, Sharp GC. Plasma cell interstitial pneumonia and macroglobulinemia. Am J Med 1974; 56: 398 – 405.
Winterbauer RH, Riggins RCK, Griesman FA, Bauermeister DE. Pleuropulmonary manifestations of Waldenstrom’s macroglobulinemia. Chest 1974; 66: 368 – 375.
Case records of the Mass General Hospital, case 43–1982. N Engl J Med 1982; 307: 1065 – 1073.
Case records of the Mass General Hospital, case 41–1084. N Engl J Med 1984; 311: 969 – 978.
Nichols PW, Koss MN, Taylor CR, Hochholzer L. Immunoperoxidase studies in the diagnosis of 51 primary pulmonary lymphoid lesions. Lab Invest 1980; 44: 48A.
Gaulard PH, Couderc LJ, Post C, et al. Primary pulmo- 71. nary lymphoma with gastric involvement in four cases. Am Rev Respir Dis 1985; 131: A117.
Cathcart-Rake W, Bone RC, Sabonya RE, Stephens RL. Rapid development of diffuse pulmonary infiltrates in 72. histiocytic lymphoma. Am Rev Respir Dis 1978; 117: 587 – 593.
Colby TV, Dorfman RF. Malignant lymphomas involving 73. the salivary glands, Pathol Annu 1979; 14: 307 – 324.
Lewin KJ, Ranchod M, Dorfman RF. Lymphomas of the gastrointestinal tract. Cancer 1978; 42: 693 – 707.
Katzenstein ALA, Carrington CB, Liebow AA. Lymphomatoid granulomatosis. A clinicopathologic study of 152 cases. Cancer 1979; 43: 360 – 373.
Petras RE, Sebek BA, Tubbs RR. Immunomorphology of lymphomatoid granulomatosis. Am J Clin Pathol 1981; 74: 354 (Abstr).
Nichols PW, Koss M, Levine AM, Lukes RJ. Lymphomatoid granulomatosis: a T-cell disorder? Am J Med 76. 1982; 72: 467 – 471.
Colby TV, Yousem SA, Pulmonary lymphoid neoplasms. Semin Diagn Pathol 1985; 2: 183 – 196.
Kern WH, Crepeau AG, Jones JC. Primary Hodgkin’s 77. disease of the lung. Cancer 1961; 14: 1151 – 1165.
Yousem SA, Weiss LM, Colby TV. Primary pulmonary Hodgkin’s disease: a clinicopathologic study of 15 cases. 78. Cancer 1986; 57: 1217 – 1224.
Harper PG, Fisher C, McLennan K, Souhami RL. Presentation of Hodgkin’s disease as an endobronchial lesion. 79. Cancer 1984; 53: 147 – 150.
Rosenow EC, Wilson WR, Cockerill FR. Pulmonary disease in the immunocompromised host. Mayo Clin Proc 80. 1985; 60: 473 – 487.
Rossi GA, Balbi B, Risso M, Repetto M, Ravazzoni C. Acute myelomonocytic leukemia: demonstration of pulmonary involvement by bronchoalveolar lavage. Chest 81. 1985; 87: 259 – 260.
Green RA, Nichols NJ. Pulmonary involvement in leuke- 82. mia. Am Rev Respir Dis 1959; 80: 833 – 844.
Klatte EC, Yardley J, Smith EB, Rohn R, Campbell JA. The pulmonary manifestations and complications of leu- 83. kemia. AJR 1963; 89: 598 – 609.
Palosaari D, Colby TV. Bronchiolocentric chronic lym- 84. phocytic leukemia. Cancer 1986; 58: 1695 – 1698.
McCabe RE, Brooks RG, Mark JBD, Remington JS. Open 85. lung biopsy in patients with acute leukemia. Am J Med 1985; 78: 609 – 616.
Myers TJ, Solon RC, Klatsky AU, Hild DH. Respiratory failure due to pulmonary leukostasis following chemotherapy of acute nonlymphocytic leukemia. Cancer 1983; 51: 1808 – 1813.
Lester TJ, Johnson JW, Cuttner J. Pulmonary leukostasis is the single worst prognostic factor in patients with acute myelocytic leukemia and hyperleukocytosis. Am J Med 1985; 79: 43 – 48.
Yoshioka R, Yamaguchi K, Yoshinaga T, Takatsuki K. Pulmonary complications in patients with adult T-cell leukemia. Cancer 1985; 55: 2491 – 2494.
Colby TV, Carrington CB, Mark GJ. Pulmonary involvement in malignant histiocytosis: a clinicopathologic spectrum. Am J Surg Pathol 1981; 5: 61 – 73.
Wongchaowart B, Kennealy JA, Crissman J, Hawkins H. Respiratory failure in malignant histiocytosis. Am Rev Respir Dis 1981; 124: 640 – 642.
Van Heerde P, Feltkamp CA, Hart AAM, Somers R. Malignant histiocytosis and related tumors: a clinico-pathologic study of 42 cases using cytological, histochemical and ultrastructural parameters. Hematol Oncol 1984; 2: 13 – 32.
Aozasa K, Tsujimoto M, Inoue A. Malignant histiocytosis. Report of twenty-five cases with pulmonary, renal and/ or gastro-intestinal involvement. Histopathology 1985; 9: 39 – 49.
Kadin ME. T Gamma cells: a missing link between malignant histiocytosis and T cell leukemia-lymphoma. Hum Pathol 1981; 12: 771 – 772.
Marglin SI, Soulen RL, Blank N, Castellino RA. Mycosis fungoides: radiographic manifestations ofextracutaneous intrathoracic involvement. Radiology 1979; 130: 35 – 37.
Wolfe JD, Trevor ED, Kjeldsberg CR. Pulmonary manifestations of mycosis fungoides. Cancer 1980; 46: 2648 – 2653.
Carter D, Eggleston JC. Tumors of the lower respiratory tract. Atlas of tumor pathology, Ser. II, Fasc. 17. Washington DC: Armed Forces Institute of Pathology, 1980: 270 – 272.
Amin R. Extramedullary plasmacytoma of the lung. Cancer 1985; 56: 152 – 156.
Garewal H, Durk BGM. Aggressive phase of multiple myeloma with pulmonary plasma cell infiltrates. Case reports. JAMA 1982; 248: 1875 – 1876.
Case records of the Mass General Hospital, case 17–1984. N Engl J Med 1984; 310: 1103 – 1112.
Gabriel S. Multiple myeloma presenting as pulmonary infiltration. Dis Chest 1965; 47: 123 – 126.
Kaplan HS. Hodgkin’s disease. Cambridge: Harvard, 1972.
Kilgore TL, Chasen MH. Endobronchial non-Hodgkin’s lymphoma. Chest 1983; 84: 58 – 61.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer Science+Business Media New York
About this chapter
Cite this chapter
Colby, T.V. (1988). Lymphoproliferative Diseases. In: Dail, D.H., Hammar, S.P. (eds) Pulmonary Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3932-9_27
Download citation
DOI: https://doi.org/10.1007/978-1-4757-3932-9_27
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4757-3934-3
Online ISBN: 978-1-4757-3932-9
eBook Packages: Springer Book Archive