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Blaustein’s Pathology of the Female Genital Tract pp 783–847Cite as

Sex Cord-Stromal, Steroid Cell, and Other Ovarian Tumors with Endocrine, Paraendocrine, and Paraneoplastic Manifestations

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Abstract

This category of ovarian neoplasms includes all those that contain granulosa cells, theca cells, and their luteinized derivatives; Sertoli cells; Leydig cells; and fibroblasts of gonadal stromal origin, singly or in various combinations and in varying degrees of differentiation.364,369,462,466,467,468 The generic terms that have been applied most widely to these tumors reflect differing views of gonadal embryology. Those who believe that all the above cell types are derived from the mesenchyme or “specialized stroma” of the genital ridge have proposed the terms “mesenchymomas”68 and “gonadal stromal tumors” for these neoplasms.301,305 In contrast, others, recognizing that many embryologists favor the participation of coelomic and mesonephric epithelium in the formation of the sex cords, which are the proximal precursors of granulosa cells and Sertoli cells, favor the terms sex cord-mesenchyrne tumors 286,366 and sex cord-stromal tumors.378.

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References

  1. Abeler V, Kjorstad KE, Nesland JM (1988) Small cell carcinoma of the ovary. A report of six cases. Int J Gynecol Pathol 7: 315–329

    Article  PubMed  CAS  Google Scholar 

  2. Abell MR (1968) Undifferentiated malignant germ cell neoplasm (embyonal carcinoma) of the ovary with stromal luteinization. Am J Obstet Gynecol 101: 570–572

    PubMed  CAS  Google Scholar 

  3. Abouav J, Berkowitz SB, Kolb FO (1959) Reversible hypercalcemia in masculinizing hypernephroid tumor of the ovary. Report of a case. N Engl J Med 260: 1057–1062

    Article  PubMed  CAS  Google Scholar 

  4. Adeyemi SD, Grange AO, Giwa-Osagie OF, et al (1986) Adrenal rest tumor of the ovary associated with isosexual precocious pseudopuberty and cushingoid features. Eur J Pediatr 145: 236–238

    Article  PubMed  CAS  Google Scholar 

  5. Aguirre P, Scully RE (1983) Testosterone-secreting adrenal ganglioneuroma containing Leydig cells. Am J Surg Pathol 7: 699

    Article  PubMed  CAS  Google Scholar 

  6. Aguirre P, Scully RE, Delellis RA (1986) Ovarian heterologous Sertoli-Leydig cell tumors with gastrointestinal-type epithelium. An immunohsitochemical analysis. Arch Pathol Lab Med 110: 528–533.

    PubMed  CAS  Google Scholar 

  7. Aguirre P, Thor AD, Scully RE (1989) Ovarian endometrioid carcinomas resembling sex cord-stromal tumors: An immunohistological study. Int J Gynecol Pathol 8: 364–373

    Article  PubMed  CAS  Google Scholar 

  8. Aguirre P, Thor AD, Scully RE (1989) Ovarian small cell carcinoma—histogenetic considerations based on immunohistochemical and other findings. Am J Clin Pathol 92: 140–149

    PubMed  CAS  Google Scholar 

  9. Ahn GH, Chi JG, Lee SK (1986) Ovarian sex cord tumor with annular tubules. Cancer 57: 1066–1073

    Article  PubMed  CAS  Google Scholar 

  10. Aiba M, Hirayama A, Sakurada M, Naruse K, Ishikawa C, Aiba S (1990) Spironolactone rod-like structure in reninproducing Sertoli cell tumor of the ovary. Surg Pathol 3: 143–149

    Google Scholar 

  11. Aiman J, Forney JP, Parker CR (1986) Androgen and estrogen secretion by normal and neoplastic ovaries in premenopausal women. Obstet Gynecol 68: 327–332

    Article  PubMed  CAS  Google Scholar 

  12. Aiman J, Nalick RH, Jacobs A, et al (1977) The origin of androgen and estrogen in a virilized postmenopausal woman with bilateral benign cystic teratomas. Obstet Gynecol 49: 695–704

    PubMed  CAS  Google Scholar 

  13. Allan SG, Lockhart SP, Leonard RCF, Smyth JF (1984) Paraneoplastic hypercalcemia in ovarian carcinoma. Br Med J 288: 1714–1715

    Article  CAS  Google Scholar 

  14. Allander E, Wagermark J (1969) Leydig cell tumors of the ovary. Report of three cases. Acta Obstet Gynecol Scand 48: 433

    Article  PubMed  CAS  Google Scholar 

  15. Alvarez RD, Varner RE (1987) Hyperandrogenic state associated with a mucinous cystadenoma. Obstet Gynecol 69: 507–510

    PubMed  CAS  Google Scholar 

  16. Anderson MC (1972) Hilar cell tumour of the ovary. J Clin Pathol 25: 106

    Article  PubMed  CAS  Google Scholar 

  17. Anderson MC, Rees DA (1975) Gynandroblastoma of the ovary. Br J Obstet Gynaecol 82: 68

    Article  PubMed  CAS  Google Scholar 

  18. Anderson PW, Macaulay L, Do YS, et al (1989) Extrarenai renin-secreting tumors: Insights into hypertension and ovarian renin production. Medicine 68: 257–268

    Article  PubMed  CAS  Google Scholar 

  19. Andujar JJ, Enloe GR, Swift WB (1947) Brenner tumor of the ovary; 2 cases associated with postmenopausal endometrial changes. Texas J Med 43: 70–75

    PubMed  CAS  Google Scholar 

  20. Anikwue C, Dawood MY, Kramer E (1979) Granulosa and theca cell tumors. Obstet Gynecol 51: 214–220

    Google Scholar 

  21. Anstey JT, Blythe JG (1972) Fibrin degradation products and the diagnosis of ovarian carcinoma. Obstet Gynecol 52: 605–608

    Google Scholar 

  22. Arai N, Misugi K, Kamiya T, Shima S (1988) An ovarian Sertoli-Leydig cell tumor with heterologous mucinous gland and NSE-immunoreactive-cell. Arch Gynecol Obstet 243: 55–60

    Article  PubMed  CAS  Google Scholar 

  23. Armstrong DT, Papkoff H (1976) Stimulation of aromatization by endogenous and exogenous androgens in ovaries of hypophysectomized rats in vivo by FSH. Endocrinology 99: 1144–1151

    Article  PubMed  CAS  Google Scholar 

  24. Astedt B, Svanberg L, Nilsson IM (1971) Fibrin degradation products and ovarian tumours. Br Med J 4: 458–459

    Article  PubMed  CAS  Google Scholar 

  25. Astengo-Osuna C (1984) Ovarian sex-cord tumor with annular tubules. Case report with ultrastructural findings. Cancer 54: 1070–1075

    Article  PubMed  CAS  Google Scholar 

  26. Atlas SA, Sherman RL, Pasmantier MW, et al (1982) Response of active and inactive renins, aldosterone and blood pressure to chemotherapy in a patient with a possible renin-secreting ovarian carcinoma. Clin Res 30: 333A (abstr)

    Google Scholar 

  27. Axiotis CA, Lippes HA, Merino MJ, de Lanerolle NC, Stewart AF, Kinder B (1987) Corticotroph cell pituitary adenoma within an ovarian teratoma. A new cause of Cushing’s syndrome. Am J Surg Pathol 11: 218–224

    Article  PubMed  CAS  Google Scholar 

  28. Backstrom T, Mahlck C, Kjellgren O (1983) Progesterone as a possible tumor marker for “nonendocrine” ovarian malignant tumors. Gynecol Oncol 16: 129–138

    Article  PubMed  CAS  Google Scholar 

  29. Baker LRI, Brain MC, Azzopardi JG, Worlledge SM (1968) Autoimmune haemolytic anaemic associated with ovarian dermoid cyst. J Clin Pathol 21: 626

    Article  PubMed  CAS  Google Scholar 

  30. Balasa RW, Adcock LL, Prem KA, Dehner LP (1977) The Brenner tumor. Obstet Gynecol 50: 120–128

    PubMed  CAS  Google Scholar 

  31. Banner EA, Dockerty MB (1945) Theca cell tumors of the ovary. A clinical and pathological study of twenty-three cases (including thirteen new cases) with a review. Surg Gynecol Obstet 81: 234–242

    Google Scholar 

  32. Baramki TA, Leddy AL, Woodruff JD (1983) Bilateral hilus cell tumors of the ovary. Obstet Gynecol 62: 128–131

    PubMed  CAS  Google Scholar 

  33. Barnes BE (1976) Dermatomyositis and malignancy. A review of the literature. Ann Intern Med 84: 68–76

    PubMed  CAS  Google Scholar 

  34. Beauchamp PJ, Hughes RS, Schmidt WA (1989) Virilizing serous cystadenoma. Obstet Gynecol 73: 513–517

    PubMed  CAS  Google Scholar 

  35. Beck JS, Fulman HF, Lee ST (1969) Solid malignant ovarian teratoma with ‘embryoid bodies’ and trophoblastic differentiation. J Pathol 99: 67–73

    Article  PubMed  CAS  Google Scholar 

  36. Bell RJM (1977) Fetal virilisation due to maternal Krukenberg tumour. Lancet 1: 1162–1163

    Article  PubMed  CAS  Google Scholar 

  37. Benagiano G, Bigotti G, Buzzi M, et al (1988) Endocrine and morphological study of case of ovarian sex-cord tumor with annular tubules in a woman with Peutz-Jeghers syndrome. Int J Gynecol Obstet 26: 441–452

    Article  CAS  Google Scholar 

  38. Benfield GFA, Tapper-Jones L, Stout TV (1982) Androblastoma and raised serum alpha-fetoprotein with familial multinodular goitre. Case report. Br J Obstet Gynaecol 89: 323

    Article  PubMed  CAS  Google Scholar 

  39. Benjamin E, Law S, Bobrow LG (1987) Intermediate filament cytokeratin and vimentin in ovarian sex cord-stromal tumors with correlative studies in adult and fetal ovaries. J Pathol 152: 253–263

    Article  PubMed  CAS  Google Scholar 

  40. Bennett RM, Ginsberg MH, Thomsen S (1976) Carcinomatous polyarthritis. Arthritis Rheum 19: 953–959

    Article  PubMed  CAS  Google Scholar 

  41. Bennington JL, Ferguson BR, Haber SL (1968) Incidence and relative frequency of benign and malignant ovarian neoplasms. Obstet Gynecol 32: 627–732

    PubMed  CAS  Google Scholar 

  42. Berlin N1, Van Scott EJ, Clendenning WE, et al (1966) Basal cell nevus syndrome. Ann Intern Med 64: 403

    PubMed  CAS  Google Scholar 

  43. Bernstein D, Naor S, Rikover M, Menahem H (1974) Hemolytic anemia related to ovarian tumor. Obstet Gynecol 43: 276–280

    PubMed  CAS  Google Scholar 

  44. Besch PK, Byron RC, Barry RD, et al (1963) Testosterone synthesis by a Brenner tumor. Part II. In vitro biosynthetic steroid conversion of a Brenner tumor. Am J Obstet Gynecol 86: 1021–1026

    PubMed  CAS  Google Scholar 

  45. Betta P, Bellingeri D (1985) Androgenic juvenile granulosa cell tumor. Case report. Eur J Gynaecol Oncol 6: 71–74

    PubMed  CAS  Google Scholar 

  46. Bettinger JF, Jacobs H (1946) A contribution to the problem of masculinization. Med J Aust 1: 10–13

    PubMed  CAS  Google Scholar 

  47. Bjorkholm E (1980) Granulosa cell tumors: A comparison of survival in patients and matched controls. Am J Obstet Gynecol 138: 329–331

    PubMed  CAS  Google Scholar 

  48. Bjorkholm E, Pettersson F (1980) Granulosa-cell and theca-cell tumors. The clinical picture and long term outcome for the Radiumhemmet series. Acta Obstet Gynec Scand 59: 361

    Article  PubMed  CAS  Google Scholar 

  49. Bjorkholm E, Silfversward C (1981) Prognostic factors in granulosa cell tumors. Gynecol Oncol 11: 261

    Article  PubMed  CAS  Google Scholar 

  50. Bjorkholm E, Silfversward C (1980) Theca-cell tumors. Clinical features and prognosis. Acta Radiol Oncol Radiat Phys Biol 19: 241

    Article  CAS  Google Scholar 

  51. Bohm J, Roder-Weber M, Hofier H (1991) Bilateral stromal Leydig cell tumor of the ovary. Case report and literature review. Path Res Pract 187: 348–352

    Article  PubMed  CAS  Google Scholar 

  52. Boivin Y, Richart RM (1965) Hilus cell tumors of the ovary. A review with a report of 3 new cases. Cancer 18: 231

    Article  PubMed  CAS  Google Scholar 

  53. Boixeda D, Roman AL, Pascasio JM, et al (1990) Zollinger-Ellison syndrome due to gastrin-secreting ovarian cystadenocarcinoma. Case report. Acta Chir Scand 156: 409–410

    PubMed  CAS  Google Scholar 

  54. Bollen ECM, Lamers CBHW, Jansen JMBJ, et al (1981) Zollinger-Ellison syndrome due to a gastrin-producing ovarian cystadenocarcinoma. Br J Surg 68: 776–777

    Article  PubMed  CAS  Google Scholar 

  55. Bonaventura LM, Judd H, Roth LM, Cleary RE (1978) Androgen, estrogen, and progesterone production by a lipid cell tumor of the ovary. Am J Obstet Gynecol 131: 403

    PubMed  CAS  Google Scholar 

  56. Borushek S, Berger I, Echt C, Gold JJ (1965) Functioning malignant germ cell tumor of the ovary in a 4?-year-old girl. Cancer 18: 1485–1488

    Article  PubMed  CAS  Google Scholar 

  57. Boss JH, Scully RE, Wegner KH, Cohen RB (1965) Structural variations in the adult ovary—clinical significance. Obstet Gynecol 25: 747–764

    PubMed  CAS  Google Scholar 

  58. Bower JF, Erickson ER (1967) Bilateral ovarian fibromas in a 5-year-old. Am J Obstet Gynecol 99: 880

    PubMed  CAS  Google Scholar 

  59. Brain Lord (1963) The neurological complications of neoplasms. Lancet 1: 179–184

    Article  PubMed  CAS  Google Scholar 

  60. Bronstein R, Hardouin G, Henrion R (1972) Kyste mucoide virilisant au cours de la grossesse. J Gynecol Obstet Biol Reprod 1: 891–899

    CAS  Google Scholar 

  61. Brown H, Lane M (1965) Cushing’s and malignant carcinoid syndromes from ovarian neoplasm. Arch Intern Med 115: 490–494

    Article  PubMed  CAS  Google Scholar 

  62. Brown WW, Shetty KR, Rosenfeld PS (1973) Hyperthyroidism due to struma ovarii: Demonstration by radioiodine scan. Acta Endocrinol 73: 266–272

    PubMed  CAS  Google Scholar 

  63. Bruno MS, Ober WB (1959) Clincopathologic Conference. N Y State J Med 59: 4001–4007

    Google Scholar 

  64. Bullon A, Arseneau J, Prat J, Young RH, Scully RE (1981) Tubular Krukenberg tumor. A problem in histopathologic diagnosis. Am J Surg Pathol 5: 225–232

    Article  PubMed  Google Scholar 

  65. Burket RL, Rauh JL (1976) Gorlin’s syndrome: Ovarian fibromas at adolescence. Obstet Gynecol 47: 43s–44s

    PubMed  CAS  Google Scholar 

  66. Burslem RW, Langley FA, Woodcock AS (1954) A clincopathological sutdy of oestrogenic ovarian tumors. Cancer 7: 552

    Article  Google Scholar 

  67. Burton PBJ, Knight DE, Quirke P, et al (1990) Parathyroid hormone related peptide in ovarian carcinoma. J Clin Pathol 43: 784

    Article  PubMed  CAS  Google Scholar 

  68. Busby T, Anderson GW (1954) Feminizing mesenchymomas of the ovary. Am J Obstet Gynecol 68: 1391

    PubMed  CAS  Google Scholar 

  69. Calabro JJ (1967) Cancer and arthritis. Arthritis Rheum 10: 553–567

    Article  PubMed  CAS  Google Scholar 

  70. Callen JP (1986) Dermatomyositis and female malignancy. J Surg Oncol 32: 121–124

    Article  PubMed  CAS  Google Scholar 

  71. Campbell PE, Danks DM (1963) Pseudoprecocity in an infant due to a luteoma of the ovary. Arch Dis Child 38: 519

    Article  PubMed  CAS  Google Scholar 

  72. Cannon PM, Smart CR, Wilson ML, Edwards CB (1975) Hypercalcemia with ovarian granulosa cell carcinoma. Rocky Mountain Med J 72: 72–74

    PubMed  CAS  Google Scholar 

  73. Carlstrom K, Lagrelius A, von Schoultz B (1985) Serum levels of dehydroepiandrosterone sulphage and total estrone in postmenopausal women with special regard to ‘non-endocrine’ ovarian carcinoma. Acta Obstet Gynecol Scand 64: 267–268

    Article  PubMed  CAS  Google Scholar 

  74. Caron P, Roche H, Gorguet B, Martel P, Bennet A, Carton M (1990) Mammary ovarian metastases with stroma cell hyperplasia and postmenopausal virilization. Cancer 66: 1221–1224

    Article  PubMed  CAS  Google Scholar 

  75. Carreras Vescio LA, Toblli JE, Rey JA, Assai ME, De Maria HE, Marietta J (1983) Autoimmune hemolytic anemia associated with an ovarian neoplasm. Medicina 43: 415–424

    PubMed  CAS  Google Scholar 

  76. Case Records of the Massachusetts General Hospital (1970) Case 13–1970. N Engl J Med 282: 676–681

    Article  Google Scholar 

  77. Case Records of the Massachusetts General Hospital (1972) Case 11–1972. N Engl J Med 286: 594–600

    Article  Google Scholar 

  78. Case Records of the Massachusetts General Hospital (1975) Case 10,1975. N Engl J Med 292: 521

    Article  Google Scholar 

  79. Case Records of the Massachusetts General Hospital (1976) Case 14,1976. N Engl J Med 294: 772

    Article  Google Scholar 

  80. Case Records of the Massachusetts General Hospital (1976) Case 26–1976. N Engl J Med 294: 1447–1454

    Article  Google Scholar 

  81. Case Records of the Massachusetts General Hospital (1978) Case 13,1978. N Engl J Med 298: 786–792

    Article  Google Scholar 

  82. Case Records of the Massachusetts General Hospital (1983) Case 21–1983. N Engl J Med 308: 1279–1284

    Article  Google Scholar 

  83. Case Records of the Massachusetts General Hospital (1985) Case 30–1985. N Engl J Med 313: 249–257.

    Article  Google Scholar 

  84. Cashell AW, Cohen ML (1991) Masculinizing sclerosing stromal tumor of the ovary during pregnancy. Gynecol Oncol 43: 281–285

    Article  PubMed  CAS  Google Scholar 

  85. Casper S, van Nagell JR, Powell DF, et al (1981) Immuno-histochemical localization of tumor markers in epithelial ovarian cancer. Am J Obstet Gynecol 149: 154–158

    Google Scholar 

  86. Chadha S, van der Kwast TH (1989) Immunohistochemistry of ovarian granulosa cell tumors. The value of tissue specific proteins and tumor markers. Virchows Arch (A) 414: 439–445

    Article  CAS  Google Scholar 

  87. Chalvardjian A, Derzko C (1982) Gynandroblastoma. Its ultrastructure. Cancer 50: 710

    Article  PubMed  CAS  Google Scholar 

  88. Chalvardjian A, Scully RE (1973) Sclerosing stromal tumors of the ovary. Cancer 31: 664

    Article  PubMed  CAS  Google Scholar 

  89. Chan LKC, Prathap K (1970) Virilization in pregnancy associated with an ovarian mucinous cystadenoma. Am J Obstet Gynecol 108: 946–949

    PubMed  CAS  Google Scholar 

  90. Chen KTK (1986) Female genital tract tumors in PeutzJeghers syndrome. Hum Pathol 17: 858–861

    Article  PubMed  CAS  Google Scholar 

  91. Christian E (1910) Un Cas d’epitheliome a granulations de luteine d’origine probablement ovarienne. Soc Anat Ann 12: 639–641

    Google Scholar 

  92. Christman JE, Ballon SC (1990) Ovarian fibrosarcoma associated with Maffucci’s syndrome. Gynecol Oncol 37: 290–291

    Article  PubMed  CAS  Google Scholar 

  93. Chumas JC, Rosenwaks Z, Mann WJ, Finkel G, Pastore J (1984) Sertoli-Leydig cell tumor of the ovary producing alpha-fetoprotein. Int J Gynecol Pathol 3: 213–219

    Article  PubMed  CAS  Google Scholar 

  94. Civantos F, Rywlin AM (1972) Carcinomas with trophoblastic differentiation and secretion of chroionic gonadot-rophins. Cancer 29: 789–798

    Article  PubMed  CAS  Google Scholar 

  95. Clement PB, Scully RE (1980) Large solitary luteinized follicle cyst of pregnancy and puerperium. A clinico-pathological analysis of eight cases. Am J Surg Pathol 4: 431–138

    Article  PubMed  CAS  Google Scholar 

  96. Clement PB, Young RH, Scully RE (1991) Clinical syndromes associated with tumors of the female genital tract. Semin Diagn Pathol 8: 204–233

    PubMed  CAS  Google Scholar 

  97. Clement PB, Young RH, Scully RE (1988) Ovarian granulosa cell proliferations of pregnancy: A report of nine cases. Hum Pathol 19: 657–662

    Article  PubMed  CAS  Google Scholar 

  98. Clement PB, Young RH, Hanna W, Scully RE (1994) Sclerosing peritonitis associated with lutenized thecomas of the ovary. A clinicopathological analysis of six cases. Am J Surg Pathol 18: 1–13.

    Article  PubMed  CAS  Google Scholar 

  99. Cocco AE, Conway SJ (1975) Zollinger-Ellison syndrome associated with ovarian mucinous cystadenocarcinoma. N Engl J Med 293: 485–486

    Article  PubMed  CAS  Google Scholar 

  100. Cocconi G, Ceci G, Juvarra G, et al (1985) Successful treatment of subacute cerebellar degeneration in ovarian carcinoma with plasmapheresis. A case report. Cancer 56: 2318–1320

    Article  PubMed  CAS  Google Scholar 

  101. Cohen PR, Kohn SR, Kurzrock R (1991) Association of sebaceous gland tumors and internal malignancy: The Muir-Torre syndrome. Am J Med 90: 606–613

    PubMed  CAS  Google Scholar 

  102. Connor TB, Ganis FM, Levin HS, Migeon CJ, Martin LG (1968) Gonadotropin-dependent Krukenberg tumor causing virilization during pregnancy. J Clin Endocrinol Metab 28: 198–214

    Article  PubMed  CAS  Google Scholar 

  103. Cotton DH, Hanson FW, Oi RH (1981) A mucinous cystadenoma associated with testosterone production. J Reprod Med 26: 276–278

    PubMed  CAS  Google Scholar 

  104. Croft PB, Wilkinson M (1965) The incidence of carcino-matous neuromyopathy in patients with various types of carcinoma. Brain 88: 427–434

    Article  PubMed  CAS  Google Scholar 

  105. Curth HO, Hilberg AW, Machacek GF (1962) The site and histology of the cancer associated with malignant acanthosis nigricans. Cancer 15: 364–382

    Article  PubMed  CAS  Google Scholar 

  106. Czernobilsky B (1984) Immunohistochemistry of normal tissues of the female genital tract. Presentation at XVth International Congress of International Academy of Pathology, Miami Beach, FL.

    Google Scholar 

  107. DaCosta CC (1938) Tumor masculinizante. Rev Gynecol Obstet 2: 3–9

    Google Scholar 

  108. Dales M (1965) Purpura associated with ovarian tumor. Br Med J 1: 127

    Article  PubMed  CAS  Google Scholar 

  109. Damjanov I, Drobnjak P, Grizelj V, Longhino N (1975) Sclerosing stromal tumor of the ovary. A hormonal and ultrastructural analysis. Obstet Gynecol 45: 675–679

    Article  Google Scholar 

  110. Dardi LE, Miller AW, Gould VE (1982) Sertoli-Leydig cell tumor with endometrioid differentiation. Case report and discussion of histogenesis. Diagn Gynecol Obstet 4: 227–234

    PubMed  CAS  Google Scholar 

  111. Davidson BJ, Waisman J, Judd HL (1981) Long-standing virilism in a woman with hyperplasia and neoplasia of ovarian lipidic cells. Obstet Gynecol 58: 753–759

    PubMed  CAS  Google Scholar 

  112. Dawson MA, Talbert W, Yarbro JW (1971) Hemolytic anemia associated with an ovarian tumor. Am J Med 50: 552

    Article  PubMed  CAS  Google Scholar 

  113. DeBruyere M, Sokal G, Devoitille JM, Fauchet-Dutrieux MC, De Spa V (1971) Autoimmune haemolytic anaemia and ovarian tumour. Br J Haemat 20: 83

    Article  CAS  Google Scholar 

  114. Delgado G, Smith JP (1975) Gynecological malignancy associated with non-bacterial thrombotic endocarditis (NBTE). Gynecol Oncol 3: 205–209

    Article  PubMed  CAS  Google Scholar 

  115. de Lima GR, de Lima OA, Baracat EC, Vasserman J, Burnier M (1989) Virilizing Brenner tumor of the ovary: Case report. Obstet Gynecol 73: 895–898

    PubMed  Google Scholar 

  116. DeTorres EF (1974) Feminization in tumors of Sertoli-Leydig cells. Acta Cytol 18: 187

    Google Scholar 

  117. Dickersin GR, Kline IW, Scully RE (1982) Small cell carcinoma of the ovary with hypercalcemia. A report of eleven cases. Cancer 49: 188

    Article  PubMed  CAS  Google Scholar 

  118. Dikman SH, Toker C (1971) Strumal carcinoid of the ovary with masculinization. Cancer 27: 925–930

    Article  PubMed  CAS  Google Scholar 

  119. Diddle AW (1951) Granulosa-and theca-cell ovarian tumors: Prognosis. Cancer 15: 215–228

    Google Scholar 

  120. Dingley ER, Marten RH (1957) Adenocarcinoma of the ovary presenting as acanthosis nigricans. J Obstet Gynaecol Br Commonw 64: 898–900

    Article  CAS  Google Scholar 

  121. Disaia PJ, Saltz A, Kagan AR, Rich W (1978) A temporary response of recurrent granulosa cell tumor to adriamycin. Obstet Gynecol 52: 355

    PubMed  CAS  Google Scholar 

  122. Dockerty MB, MacCarty WC (1939) Granulosa cell tumors; with the report of a 34-lb specimen and a review. Am J Obstet Gynecol 37: 425

    Google Scholar 

  123. Dockerty MB, Masson JC (1944) Ovarian fibromas: A clinical and pathologic study of two hundred and eighty-three cases. Am J Obstet Gynecol 47: 741

    Google Scholar 

  124. Dorrington JH, Moon YS, Armstrong DT (1975) Estradiol-17B biosynthesis in cultured granulosa cells from hypophy-sectomized immature rats: Stimulation by FSH. Endocrinology 97: 1328–1331

    Article  PubMed  CAS  Google Scholar 

  125. Dunaif A, Hoffman AR, Scully RE, et al (1985) Clinical, biochemical, and ovarian morphologic features in women with acanthosis nigricans and masculinization. Obstet Gynecol 66: 545–552

    PubMed  CAS  Google Scholar 

  126. Duncan SC, Winkelmann RK (1979) Cancer and scleroderma. Arch Dermatol 115: 950–955

    Article  PubMed  CAS  Google Scholar 

  127. Dunnihoo DR, Grieme DL, Woolf RB (1966) Hilar-cell tumors of the ovary. Report of 2 new cases and a review of the world literature. Obstet Gynecol 27: 703

    PubMed  CAS  Google Scholar 

  128. Echt CR, Hadd HE (1968) Androgen excretion patterns in a patient with a metastatic hilus cell tumor of the ovary. Am J Obstet Gynecol 100: 1055

    PubMed  CAS  Google Scholar 

  129. Eddie DAS (1967) Hormonal activity with ovarian tumours. J Obstet Gynaecol Br Commonw 74: 283–285

    Article  PubMed  CAS  Google Scholar 

  130. Ehrlich EN, Dominguez OV, Samuels LT, Lynch D, Oberhelman H, Warner NE (1963) Aldosteronism and precocious puberty due to an ovarian androblastoma (Sertoli cell tumor). J Clin Endocrinol Metab 23: 358–367

    Article  CAS  Google Scholar 

  131. Eichhorn JH, Bell DA, Young RH, et al (1992) DNA content and proliferative activity in ovarian small cell carcinomas of the hypercalcemic type. Implications for diagnosis, prognosis and histogenesis. Am J Clin Pathol 98: 579–586

    PubMed  CAS  Google Scholar 

  132. Emig OR, Hertig AT, Rowe FJ (1959) Gynandroblastoma of the ovary. Review and report of a case. Obstet Gynecol 13: 135

    Article  PubMed  CAS  Google Scholar 

  133. Evans AT, Gaffey TA, Malkasian GD Jr, Annegers JF (1980) Clinicopathologic review of 118 granulosa and 82 theca cell tumors. Obstet Gynecol 55: 231

    PubMed  Google Scholar 

  134. Falls JL (1955) Accessory adrenal cortex in the broad ligament. Incidence and functional significance. Cancer 8: 143

    Article  PubMed  CAS  Google Scholar 

  135. Fathalla MF (1967) The occurrence of granulosa and theca tumors in clinically normal ovaries. A study of 25 cases. J Obstet Gynaecol Br Commonw 74: 279

    Article  Google Scholar 

  136. Fathalla MF (1968) The role of the ovarian stroma in hormone production by ovarian tumors. J Obstet Gynaecol Br Commonw 75: 78–83

    Article  PubMed  CAS  Google Scholar 

  137. Fathizadeh A, Medenica MM, Soltani K, et al (1982) Aggressive keratoacanthoma and internal malignant neoplasm. Arch Dermatol 118: 112–114

    Article  PubMed  CAS  Google Scholar 

  138. Fawcett FJ, Kimbell NKB (1971) Phaeochromocytoma of the ovary. J Obstet Gynaecol Br Commonw 78: 458–459

    Article  PubMed  CAS  Google Scholar 

  139. Fayez JA, Bunch TR, Miller GL (1974) Virilization in pregnancy associated with an ovarian serous cystadenoma. Am J Obstet Gynecol 120: 341–346

    PubMed  CAS  Google Scholar 

  140. Fenoglio CM, Hayata T, Crum CP, Richart RM (1982) The expression of human chorionic gonadotrophin in the female genital tract. Localization by the immunoperoxidase technique. Diagn Gynecol Obstet 4: 94–97

    Google Scholar 

  141. Ferenczy A, Okagaki T, Richart RM (1971) Para-endocrine hypercalcemia in ovarian neoplasms. Report of mesonephroma with hypercalcemia and review of literature. Cancer 27: 427–433

    Article  PubMed  CAS  Google Scholar 

  142. Ferenczy A, Richart RM (1974) Female reproductive system: Dynamics of scan and transmission electron microscopy. New York, John Wiley amp; Sons.

    Google Scholar 

  143. Ferry JA, Young RH, Engel G, Scully RE (in press) Oxyphilic sertoli cell tumor of the ovary: A report of three cases, two in patients with the Peutz-Jeghers Syndrome. Int J Gynecol Pathol.

    Google Scholar 

  144. Fetissof F, Berger G, Dubois MP, et al (1985) Female genital tract and Peutz-Jeghers syndrome: An immunohis-tochemical study. Int J Gynecol Pathol 4: 219–229

    Article  PubMed  CAS  Google Scholar 

  145. Fleischhacker DS, Young RH (in press) Dysgerminoma of the ovary associated with hypercalcemia. Gynecol Oncol.

    Google Scholar 

  146. Forest MG, Orgiazzi J, Tranchant D, Mornex R, Bertrand J (1978) Approach to the mechanism of androgen overproduction in a case of Krukenberg tumor responsible for virilization during pregnancy. J Clin Endocrinol Metab 47: 428–434

    Article  PubMed  CAS  Google Scholar 

  147. Fox H (1965) Estrogenic activity of the serous cystadenoma of the ovary. Cancer 18: 1041–1047

    Article  PubMed  CAS  Google Scholar 

  148. Fox H, Agrawal K, Langley FA (1975) A clinicopathological study of 92 cases of granulosa cell tumor of the ovary with special reference to the factors influencing prognosis. Cancer 35: 231

    Article  PubMed  CAS  Google Scholar 

  149. Fox LP, Stamm WJ (1965) Krukenberg tumor complicating pregnancy. Report of a case with androgenic activity. Am J Obstet Gynecol 92: 702–710

    PubMed  CAS  Google Scholar 

  150. Franke WW, Grund C, Schmid E (1979) Intermediatesized filaments in Sertoli are of vimentin-type. Eur J Cell Biol 19: 269–275

    PubMed  CAS  Google Scholar 

  151. Fujino T, Watanabe T, Yamaguchi K, et al (1992) The development of hypercalcemia in a patient with an ovarian tumor producing parathyroid hormone-related protein. Cancer 70: 2845–2850

    Article  PubMed  CAS  Google Scholar 

  152. Fung MFK, Vadas G, Lotocki R, Heywood M, Krepart G (1991) Tubular Krukenberg tumor in pregnancy with virilization. Gynecol Oncol 41: 81–84

    Article  PubMed  CAS  Google Scholar 

  153. Gaffney EF, Majmudar B, Hertzler GL, Zane R, Furlong B, Breding E (1983) Ovarian granulosa cell tumors—im-munohistochemical localization of estradiol and ultrastructure, with functional correlations. Obstet Gynecol 61: 311–318

    PubMed  CAS  Google Scholar 

  154. Gagnon S, Tetu B, Silva EG, McCaughey WTE (1989) Frequency of α-fetoprotein production by Sertoli-Leydig cell tumors of the ovary: an immunohistochemical study of eight cases. Mod Pathol 2: 6S–67

    Google Scholar 

  155. Garcia-Villaneuva M, Figuerola NB, del Arbol LR, Ortiz MJH (1990) Zollinger-Ellison syndrome due to a borderline mucinous cystadenoma of the ovary. Obstet Gynecol 75: 549–551

    Google Scholar 

  156. Garneau R, Cabanne F (1968) Dysembryome ovarien de type enteroide et bilio-Berger. A propos d’une observation. Ann Anat Pathol 13: 423–432

    CAS  Google Scholar 

  157. Gee DC, Russell P (1979) Sclerosing stromal tumours of the ovary. Histopathology 3: 367–376

    Article  PubMed  CAS  Google Scholar 

  158. Gee DC, Russell P (1981) The pathological assessment of ovarian neoplasms. IV: The sex cord stromal tumors. Pathology 13: 235–255

    Article  PubMed  CAS  Google Scholar 

  159. Geist SH, Gaines JA (1938) Theca cell tumors. Am J Obstet Gynecol 35: 39–51

    Google Scholar 

  160. Genton CY (1980) Ovarian Sertoli-Leydig cell tumors. A clinical, pathological and ultrastructural study with particular reference to the histogenesis of these tumors. Arch Gynecol 230: 49–75

    Article  PubMed  CAS  Google Scholar 

  161. Genton CY (1980) Some observations on the fine structure of human granulosa cell tumors. Virchows Arch A Path Anat Histol 387: 353–369

    Article  CAS  Google Scholar 

  162. Ghio R, Haupt E, Ratti M, Boccaccio P (1981) Erythrocytosis associated with a dermoid cyst of the ovary and erythropoietic activity of the tumour fluid. Scand J Haematol 27: 70–74

    Article  PubMed  CAS  Google Scholar 

  163. Givens JR (1976) Hirsutism and hyperandrogenism. Adv Intern Med 21: 221–247

    PubMed  CAS  Google Scholar 

  164. Givens JR, Kerber IJ, Wiser WL, Anderson RW, Coleman SA, Fish SA (1974) Remission of acanthosis nigricans associated with polycystic ovarian disease and a stromal luteoma. J Clin Endocrinol Metab 38: 347

    Article  PubMed  CAS  Google Scholar 

  165. Glaser D, Nienhaus H, Köhler R, Walther G, Pawlowitzki IH (1988) A sex cord stromal tumour in a woman with XO/XX/XXX-mosaicism. Arch Gynecol Obstet 243: 115–118

    Article  PubMed  CAS  Google Scholar 

  166. Goldberg B, Seegar Jones GE, Woodruff JD (1963) A histochemical study of steroid 3β-ol dehydrogenase activity in some steroid-producing tumors. Am J Obstet Gynecol 86: 1003–1014

    PubMed  CAS  Google Scholar 

  167. Gondos B, Monroe SA (1971) Cystic granulosa cell tumor with massive hemoperitoneum. Light and electron microscopic study. Obstet Gynecol 38: 683–689

    PubMed  CAS  Google Scholar 

  168. Gorlin RJ (1987) Nevoid basal-cell carcinoma syndrome. Medicine 66: 98–113

    Article  PubMed  CAS  Google Scholar 

  169. Gorlin RJ, Sedano HO (1971) The multiple nevoid basal cell carcinoma syndrome revisited. Birth Defects 7: 140

    PubMed  CAS  Google Scholar 

  170. Gorlin RJ, Vickers RA, Kelln E, Williamson JJ (1965) The multiple basal cell nevi syndrome. Cancer 18: 89

    Article  PubMed  CAS  Google Scholar 

  171. Graham R, McKee P, McGibbon D, et al (1985) Torre-Muir syndrome. An association with isolated sebaceous carcinoma. Cancer 55: 2868–2873

    Article  PubMed  CAS  Google Scholar 

  172. Greco MA, LiVolsi VA, Pertschuk KP, Bigelow B (1979) Strumal carcinoid of the ovary. An analysis of its components. Cancer 43: 1380–1388

    Article  PubMed  CAS  Google Scholar 

  173. Greenlee JE, Brashear HR (1983) Antibodies to cerebellar Purkinje cells in patients with paraneoplastic cerebellar degeneration and ovarian carcinoma. Ann Neurol 14: 609–613

    Article  PubMed  CAS  Google Scholar 

  174. Grenet P, Badoual J, Gallet JP, et al (1972) Dyschondro-plasie et tumeur de l’ovaire. Ann Pediatr (Paris) 19: 759–764

    CAS  Google Scholar 

  175. Guerard MJ, Ferenczy A, Arguelles MA (1982) Ovarian Sertoli-Leydig cell tumor with rhabdomyosarcoma: An ultrastructural study. Ultrastruct Pathol 3: 347

    Article  PubMed  CAS  Google Scholar 

  176. Guintoli RL, Celebre JA, Wu CH, Wheeler JE, Mikuta JJ (1976) Androgenic function of a granulosa cell tumor. Obstet Gynecol 47: 77

    Google Scholar 

  177. Gusberg SB, Kardon P (1967) Proliferative endometrial response to theca-granulosa cell tumors. Am J Obstet Gynecol 111: 633

    Google Scholar 

  178. Gustafson ML, Lee MM, Scully RE, et al (1992) Mullerian inhibiting substance as a marker for ovarian sex-cord tumor. N Engl J Med 326: 466–471

    Article  PubMed  CAS  Google Scholar 

  179. Hall DJ, Dyer ML, Parker JC (1985) Ovarian cancer complicated by cerebellar degeneration: A paraneoplastic syndrome. Gynecol Oncol 21: 240–246

    Article  PubMed  CAS  Google Scholar 

  180. Hameed H (1972) Brenner tumor of the ovary with Leydig cell hyperplasia. A histologic and ultrastructural study. Cancer 30: 945–952

    Article  PubMed  CAS  Google Scholar 

  181. Hammack JE, Kimmel DW, O’Neill BP, et al (1990) Paraneoplastic cerebellar degeneration: A clinical comparison of patients with and without Purkinje cell cytoplasmic antibodies. Mayo Clin Proc 65: 1423–1431

    Article  PubMed  CAS  Google Scholar 

  182. Hammond D, Winnick S (1974) Paraneoplastic erythrocytosis and ectopic erythropoietins. Ann NY Acad Sci 230: 219–227

    Article  PubMed  CAS  Google Scholar 

  183. Hamwi GJ, Byron RC, Besch PK, Vorys N, Teteris NJ, Ullery JC (1963) Testosterone synthesis by a Brenner tumor. Part I. Clinical evidence of masculinization during pregnancy. Am J Obstet Gynecol 86: 1015–1020

    PubMed  CAS  Google Scholar 

  184. Hart WR, Kumar N, Crissman JD (1980) Ovarian neoplasms resembling sex cord tumors with annular tubules. Cancer 45: 2352–2363

    Article  PubMed  CAS  Google Scholar 

  185. Hasleton PS, Kelehan P, Whittaker JS, Burslen RW, Turner L (1978) Benign and malignant struma ovarii. Arch Pathol Lab Med 102: 180–184

    PubMed  CAS  Google Scholar 

  186. Hayes MC, Scully RE (1987) Ovarian steroid cell tumor (not otherwise specified): A clinicopathological analysis of 63 cases. Am J Surg Pathol 11: 835–845

    Article  PubMed  CAS  Google Scholar 

  187. Hayes MC, Scully RE (1987) Stromal luteoma of the ovary: A clinico-pathological analysis of 25 cases. Int J Gynecol Pathol 6: 313–321

    Article  PubMed  CAS  Google Scholar 

  188. Heinonen PK, Koivula T, Pystynen P (1989) Elevated progesterone levels in serum and ovarian venous blood in patients with ovarian tumors. Acta Obstet Gynecol Scand 64: 649–652

    Article  Google Scholar 

  189. Heinonen PK, Koivula T, Rajaniemi H, et al (1986) Peripheral and ovarian venous concentrations of steroid and gonadotropin hormones in postmenopausal women with epithelial ovarian tumors. Gynecol Oncol 25: 1–10

    Article  PubMed  CAS  Google Scholar 

  190. Henson RA, Urich H (1982) Cancer and the nervous system: The neurological manifestations of systemic malignant disease. Boston, Blackwell Scientific Publications

    Google Scholar 

  191. Herrington JB, Scully RE (1983) Endocrine aspects of germ cell tumors. In: Damjanov I, Knowles B and Solter D (eds) The Human Teratomas. New York, The Humana Press.

    Google Scholar 

  192. Herruzo, Redondo E, De Avila IP, et al (1990) Ovarian sex cord tumor with annular tubules and Peutz-Jeghers syndrome. Eur J Gynaecol Oncol 11: 141–144

    PubMed  CAS  Google Scholar 

  193. Herve JP, Leroy JP, Gentric-Tilly A, et al (1989) Hypertension arterielle secondaire a une tumeur a renine d’origine ovarienne. Presse Med 18: 2021–2022

    PubMed  CAS  Google Scholar 

  194. Hetzel DJ, Stanhope R, O’Neill BP, et al (1990) Gynecologic cancer in patients with subacute cerebellar degeneration predicted by anti-Purkinje cell antibodies and limited in metastatic volume. Mayo Clin Proc 65: 1558–1563

    Article  PubMed  CAS  Google Scholar 

  195. Heyd J, Livni N, Herbert D, Mor-Yosef S, Glaser B (1989) Gastrin-producing ovarian cystadenocarcinoma: Sensitivity to secretin and SMS 201-995. Gastroenterology 97: 464–467

    PubMed  CAS  Google Scholar 

  196. Hoekman K, Tjandra Y, Papapoulos SE (1991) The role of 1,25-dihydroxyvitamin D in the maintenance of hypercalcemia in a patient with an ovarian carcinoma producing parathyroid hormone-related protein. Cancer 68: 642–647

    Article  PubMed  CAS  Google Scholar 

  197. Holguin T, Padilla RS, Ampuero F (1986) Ovarian adeno-carcinoma presenting with the sign of Leser-Trelat. Gynecol Oncol 25: 128–132

    Article  PubMed  CAS  Google Scholar 

  198. Holtz G, Johnson TR Jr, Schrock ME (1979) Paraneoplastic hypercalcemia in ovarian tumors. Obstet Gynecol 54: 483–487

    PubMed  CAS  Google Scholar 

  199. Hoyt RE, Hamilton JF (1987) Ovarian cancer associated with the nephrotic syndrome. Obstet Gynecol 70: 513–514

    PubMed  CAS  Google Scholar 

  200. Hsu C, Ma L, Mak L (1983) Sclerosing stremai tumor of the ovary: Case report and review of the literature. Int J Gynecol Pathol 2: 192–200

    Article  PubMed  CAS  Google Scholar 

  201. Huang TY, Holaday WJ (1970) An ovarian hilus cell tumor associated with endometrial carcinoma: Report of a case. Am J Clin Pathol 54: 147

    PubMed  CAS  Google Scholar 

  202. Hughesdon PE (1958) Thecal and allied reactions in epithelial ovarian tumours. J Obstet Gynaecol Br Commonw 65: 702–709

    Article  CAS  Google Scholar 

  203. Hughesdon PE (1983) Lipid cell thecomas of the ovary. Histopathology 7: 681–692

    Article  PubMed  CAS  Google Scholar 

  204. Hughesdon PE, Fraser IT (1953) Arrhenoblastoma of ovary. Case report and historical review. Acta Obstet Gynecol Scand (suppl 4)32: 1.

    Article  CAS  Google Scholar 

  205. Ichinohasama R, Teshima S, Kishi K, et al (1989) Leydig cell tumor of the ovary associated with endometrial carcinoma and containing 17 beta-hydroxysteroid dehydrogenase. Int J Gynecol Pathol 8: 64–71

    Article  PubMed  CAS  Google Scholar 

  206. Imai A, Furui T, Shimokawa K, Tamaya T (1992) Juvenile granulosa cell tumor in a 2-year-old infant: Report of a case complicated with ascites and acute respiratory distress. Gynecol Oncol 46: 397–400

    Article  PubMed  CAS  Google Scholar 

  207. Ismail SM, Walker SM (1990) Bilateral virilizing sclerosing stremai tumours of the ovary in a pregnant woman with Gorlin’s syndrome: Implications for pathogenesis of ovarian stremai neoplasms. Histopathology 17: 159–163

    Article  PubMed  CAS  Google Scholar 

  208. Iturzaeta N, Kenny FM, Sieber W (1967) Precocious pseudopuberty due to granulosa cell tumor in three girls. Am J Dis Child 114: 39

    Google Scholar 

  209. Jackson B, Valentine R, Wagner G (1986) Primary aldosteronism due to a malignant ovarian tumour. Aust NZ J Med 16: 69–71

    Article  CAS  Google Scholar 

  210. Jacobs AJ, Deppe G, Cohen CJ (1982) Combination chemotherapy of ovarian granulosa cell tumor with CIS-platinum and doxorubicin. Gynecol Oncol 14: 294

    Article  PubMed  CAS  Google Scholar 

  211. Jarabak J, Talerman A (1983) Virilization due to a metastasizing granulosa cell tumor. Int J Gynecol Pathol 2: 316–324

    Article  PubMed  CAS  Google Scholar 

  212. Jeppsson S, Karlsson S, Kuliander S (1986) Gonadal steroids, gonadotropins and endometrial histology in postmenopausal women with malignant ovarian tumors. Acta Obstet Gynecol Scand 65: 207–210

    Article  PubMed  CAS  Google Scholar 

  213. Johnson AD, Herbert AA, Esterly NB (1986) Nevoid basal cell carcinoma syndrome. Bilateral ovarian fibromas in a 3½rld girl. J Am Acad Dermatol 14: 371–374

    Article  PubMed  CAS  Google Scholar 

  214. Johnston WW, Goldston WR, Montgomery MS (1971) Clinicopathologic studies in feminizing tumors of the ovary. III. The role of genital cytology. Acta Cytol 15: 334

    PubMed  CAS  Google Scholar 

  215. Jolies CJ, Beeson JH, Abbott T (1985) Progesterone production in adenocarcinoma of the colon metastatic to the ovaries. Obstet Gynecol 65: 853–857

    Google Scholar 

  216. Jolly H (1955) Sexual Precocity. A personal study of 69 patients. American Lecture Series, Springfield, IL, Charles Thomas.

    Google Scholar 

  217. Jorgensen EO, Dockerty MB, Wilson RB (1970) Clinicopathologic study of 53 cases of Brenner tumors of the ovary. Am J Obstet Gynecol 108: 122–127

    PubMed  CAS  Google Scholar 

  218. Josse RG, Wilson DR, Heersche JNM, Mills JRF, Murray TM (1981) Hypercalcemia with ovarian carcinoma: Evidence of a pathogenetic role for prostaglandins. Cancer 48: 1233–1241

    Article  PubMed  CAS  Google Scholar 

  219. Judd HL, Spore WW, Talner LB, Rigg LA, Yen SSC, Benirschke K (1974) Preoperative localization of a testosterone-secreting ovarian tumor by retrograde venous catheterization and selective sampling. Am J Obstet Gynecol 120: 91

    PubMed  CAS  Google Scholar 

  220. Julkunen R, Partanen S, Salaspuro M (1983) Gastrin-producing ovarian mucinous cystadenoma. J Clin Gastroenterol 5: 67–70

    Article  PubMed  CAS  Google Scholar 

  221. Junaid TA, Nkposong EO, Kolawole TM (1972) Cutaneous meningiomas and an ovarian fibroma in a 3-year-old girl. J Pathol 108: 165

    Article  PubMed  CAS  Google Scholar 

  222. Kalavathi N (1971) Granulosa cell tumor—hormonal aspects and radiosensitivity. Clin Radiol 22: 524–527

    Article  PubMed  CAS  Google Scholar 

  223. Kallenberg GA, Pesce CM, Norman B, Ratner RE, Silverberg SG (1990) Ectopic hyperprolactinemia resulting from an ovarian teratoma. JAMA 263: 2472–2474

    Article  PubMed  CAS  Google Scholar 

  224. Kaplan C, Hawley R (1981) Dysgerminoma with giant cells. A case report with immunoperoxidase. Diagn Gynecol Obstet 3/4: 325–329.

    PubMed  CAS  Google Scholar 

  225. Katsube Y, Berg JM, Silverberg SG (1982) Epidemiologic pathology of ovarian tumors: A histopathologic review of primary ovarian neoplasms dia area, 1 July–31 December 1969 and 1 July–31 December 1979. Int J Gynecol Pathol 1: 3–16

    Article  PubMed  CAS  Google Scholar 

  226. Katsube Y, Iwaoki Y, Silverberg SG, Fujiwara A (1988) Sclerosing stremai tumor of the ovary associated with endometrial adenocarcinoma. A case report. Gynecol Oncol 29: 392–398

    Article  PubMed  CAS  Google Scholar 

  227. Kempers RD, Dockerty MB, Hoffman DL, et al (1970) Struma ovarii—ascitic, hyperthyroid, and asymptomatic syndromes. Ann Intern Med 72: 883–893

    PubMed  CAS  Google Scholar 

  228. Kempson RL (1968) Ultrastructure of ovarian stremai cell tumors. Sertoli-Leydig cell tumor and lipid cell tumor. Arch Pathol 86: 492

    PubMed  CAS  Google Scholar 

  229. Khalifa MA, Sesterhenn IA (1990) Tumor markers of epithelial ovarian neoplasms. Int J Gynecol Pathol 9: 217–230

    Article  PubMed  CAS  Google Scholar 

  230. Kim I, Young RH, Scully RE (1985) Leydig cell tumors of the testis. A clinicopathological analysis of 40 cases and review of the literature. Am J Surg Pathol 9: 177–192

    Article  PubMed  CAS  Google Scholar 

  231. Kobayashi M, Hamada H, Yamoto M, et al (1990) Ovarian clear-cell carcinoma producing estradiol and human chorionic gonadotropin. Acta Obstet Gynecol Scand 69: 183–185

    Article  PubMed  CAS  Google Scholar 

  232. Konishi I, Fujii S, Ishikawa Y, Suzuki A, Okamura H, Mori T (1986) Ovarian fibroma with Leydig cell hyperplasia of the adjacent strema: A light and electron microscopic study. Int J Gynecol Pathol 5: 170–178

    PubMed  CAS  Google Scholar 

  233. Korzets A, Nouriel H, Steiner Z, et al (1986) Resistant hypertension associated with a renin-producing ovarian Sertoli cell tumor. Am J Clin Pathol 85: 242–247

    PubMed  CAS  Google Scholar 

  234. Kottmeier HL (1953) Carcinoma of the Female Genitalia. The Abraham Flexner Lectures, Series No. 11, Baltimore, Williams and Wilkins.

    Google Scholar 

  235. Kraemer BB, Silva EG, Sneige N (1984) Fibrosarcoma of the ovary. A new component in the nevoid basal-cell carcinoma syndrome. Am J Surg Pathol 8: 231–236

    Article  PubMed  CAS  Google Scholar 

  236. Kuhnel R, Rao BR, Stolk JG, van Kessel H, Seldernrijk CA, Willig AP (1987) Estrogen synthesizing rare malignant Brenner tumor of the ovary with the presence of progesterone and androgen receptors in the absence of estrogen receptors. Gynecol Oncol 26: 263–269

    Article  PubMed  CAS  Google Scholar 

  237. Kulkarni JN, Mistry RC, Kamat MR, Chinoy R, Lotlikar RG (1990) Autonomous aldosterone-secreting ovarian tumor. Gynecol Oncol 37: 284–289

    Article  PubMed  CAS  Google Scholar 

  238. Kung AWC, Ma JTC, Wang C, et al (1990) Hyperthyroidism during pregnancy due to coexistence of struma ovarii and Graves’ disease. Postgrad Med J 66: 132–133

    Article  PubMed  CAS  Google Scholar 

  239. Kurman RJ, Andrade D, Goebelsmann U, Taylor CR (1978) An immunohistochemical study of steroid localization in Sertoli-Leydig tumors of the ovary and testis. Cancer 42: 1772

    Article  PubMed  CAS  Google Scholar 

  240. Kurman RJ, Ganjei P, Nadjii M (1984) Contributions of immunocytochemistry to the diagnosis and study of ovarian neoplasms. Int J Gynecol Pathol 3: 3–26

    Article  PubMed  CAS  Google Scholar 

  241. Kurman RJ, Goebelsmann U, Taylor CR (1979) Steroid localization in granulosa-theca tumors of the ovary. Cancer 43: 2377

    Article  PubMed  CAS  Google Scholar 

  242. Kurman RJ, Noms HJ (1976) Malignant mixed germ cell tumors of the ovary. Obstet Gynecol 48: 579–589

    PubMed  CAS  Google Scholar 

  243. Kurman RJ, Noms HJ (1976) Embryonal cell carcinoma of the ovary. A clinicopathologic entity distinct from endodermal sinus tumor resembling embryonal carcinoma of the adult testis. Cancer 38: 2420–2433

    Article  PubMed  CAS  Google Scholar 

  244. Kuzma JF, King JM (1948) Dyschondroplasia with hemangiomatosis (Maffucci’s syndrome) and teratoid tumor of the ovary. Arch Pathol 46: 74

    CAS  Google Scholar 

  245. Lack EE, Perez-Atayde AR, Murthy ASK, Goldstein DP, Crigler JF, Vawter GF (1981) Granulosa theca cell tumors in premenarchal girls. A clinical and pathologic study of ten cases. Cancer 48: 1846

    Article  PubMed  CAS  Google Scholar 

  246. Lawhead RA, Copeland LJ, Edwards CL (1985) Bilateral ovarian hemangiomas associated with diffuse abdominopelvic hemangiomatosis. Obstet Gynecol 65: 597–599

    PubMed  CAS  Google Scholar 

  247. Lee JC, Yamauchi H, Hopper J Jr (1966) The association of cancer and the nephrotic syndrome. Ann Intern Med 64: 41–57

    PubMed  CAS  Google Scholar 

  248. Lewis RJ, Ketcham AS (1973) Maffucci’s syndrome: Functional and neoplastic significance. Case report and review of the literature. J Bone Joint Surg 55-A: 1465.

    PubMed  CAS  Google Scholar 

  249. Listrom WB, Foucar CE (1990) Letter to the Editor. Am J Clin Pathol 94: 803–804

    PubMed  CAS  Google Scholar 

  250. Long TT, Barton TK, Draffin R, Reeves WJ, McCarty KS (1980) Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. JAMA 243: 1837–1839

    Article  PubMed  Google Scholar 

  251. Lusch CJ, Mercurio TM, Runyeon WK (1978) Delayed recurrence and chemotherapy of a granulosa cell tumor. Obstet Gynecol 51: 505

    Article  PubMed  CAS  Google Scholar 

  252. Lyday RO (1952) Fibroma of the ovary with abdominal implants. Am J Surg 84: 737

    Article  PubMed  CAS  Google Scholar 

  253. MacAulay MA, Weliky I, Schulz RA (1967) Ultrastructure of a biosynthetically active granulosa cell tumor. Lab Invest 17: 562–570

    PubMed  CAS  Google Scholar 

  254. MacKenzie AH, Scherbel AL (1963) Connective tissue syndromes associated with carcinoma. Geriatrics 18: 745–753

    PubMed  CAS  Google Scholar 

  255. Mahlck C, Backstrom T, Kjellgren O (1986) Androstenedione production by malignant epithelial ovarian tumors. Gynecol Oncol 25: 217–222

    Article  PubMed  CAS  Google Scholar 

  256. Mahlck C, Backström T, Kjellgren O (1988) Plasma level of estradiol in patients with ovarian malignant tumors. Gynecol Oncol 30: 313–320

    Article  PubMed  CAS  Google Scholar 

  257. Mahlck C-G, Grankvist K, Kjellgren O, Backstrom T (1990) Human chorionic gonadotropin, follicle-stimulating hormone, and luteinizing hormone in patients with epithelial ovarian carcinoma. Gynecol Oncol 36: 219–225

    Article  PubMed  CAS  Google Scholar 

  258. Malfetano JH, Degnan E, Florentin R (1990) Para-endocrine hypercalcemia and ovarian small cell carcinoma. NY State J Med 90: 206–207

    CAS  Google Scholar 

  259. Malkasian GD Jr, Webb MJ, Jorgensen EO (1974) Observations on chemotherapy of granulosa cell carcinomas and malignant ovarian teratomas. Obstet Gynecol 44: 885

    PubMed  Google Scholar 

  260. Mann WJ, Chumas J, Rosenwaks Z, Merrill JA, Davenport D (1986) Elevated serum alpha-fetoprotein associated with Sertoli-Leydig cell tumors of the ovary. Obstet Gynecol 67: 141–144

    PubMed  CAS  Google Scholar 

  261. March DE, Desai AG, Park CH, et al (1988) Struma ovarii: Hyperthyroidism in a postmenopausal woman. J Nucl Med 29: 263–265

    PubMed  CAS  Google Scholar 

  262. Marcus CC, Marcus SL (1961) Struma ovarii. A report of 7 cases and a review of the subject. Am J Obstet Gynecol 81: 752–762

    PubMed  CAS  Google Scholar 

  263. Margolin KA, Pak HY, Esensten ML, Doroshow JH (1985) Hepatic metastasis in granulosa cell tumor of the ovary. Cancer 56: 691–695

    Article  PubMed  CAS  Google Scholar 

  264. Marieb HJ, Spangler S, Kashgarian M, Heiman A, Schwartz ML, Schwartz PE (1983) Cushing’s syndrome secondary to ectopic cortisol production by an ovarian car-cinoma. J Clin Endocrinol Metab 57: 737–740

    Article  PubMed  CAS  Google Scholar 

  265. Martinelli G, Govoni E, Pileri S, Grigioni FW, Doglioni C, Pelusi G (1983) Sclerosing stromal tumor of the ovary. Virchows Arch (Pathol Anat) 402: 155–161

    Article  CAS  Google Scholar 

  266. Matias-Guiu X, Prat J (1990) Ovarian tumors with functioning stroma. An immunohistochemical study of 100 cases with human chorionic gonadotropin monoclonal and polyclonal antibodies. Cancer 65: 2001–2005

    Article  PubMed  CAS  Google Scholar 

  267. Matson PN, Mackem SM, Norton JA, Gardner JD, O’Dorisio TM, Jensen RT (1989) Ovarian carcinoma as a cause of Zollinger-Ellison syndrome. Natural history, secretory products, and response to provocative tests. Gastroenterology 97: 468–471

    Google Scholar 

  268. McGowan L, Young RH, Scully RE (1980) Peutz-Jeghers syndrome with adenoma malignum of cervix. A report of two cases. Gynecol Oncol 10: 125

    Article  PubMed  CAS  Google Scholar 

  269. McKay DG, Hertig AT, Hickey WF (1953) The histogenesis of granulosa and theca tumors of the human ovary. Obstet Gynecol 1: 125–136

    PubMed  CAS  Google Scholar 

  270. McKay DG, Robinson D, Hertig AT (1949) Histochemical observations on granulosa cell tumors, thecomas, and fibromas of the ovary. Am J Obstet Gynecol 58: 625–639

    PubMed  CAS  Google Scholar 

  271. McLellan R, Currie JL, Royal W, et al (1988) Ovarian carcinoma and paraneoplastic cerebellar degeneration. Obstet Gynecol 72: 922–924

    PubMed  CAS  Google Scholar 

  272. McMahon JT, Hart WR (1988) Ultrastructural analysis of small cell carcinomas of the ovary. Am J Clin Pathol 90: 523–529

    PubMed  CAS  Google Scholar 

  273. McNulty JR (1959) The ovarian serous cystadenofibroma. A report of 25 cases. Am J Obstet Gynecol 77: 1338–1344

    PubMed  CAS  Google Scholar 

  274. Medsger TA, Dixon JA, Garwood VF (1982) Palmar fasciitis and polyarthritis associated with ovarian carcinoma. Ann Intern Med 96: 424–431

    PubMed  CAS  Google Scholar 

  275. Meigs JV (1954) Fibroma of the ovary with ascites and hydrothorax. Meigs’ syndrome. Am J Obstet Gynecol 67: 962

    PubMed  CAS  Google Scholar 

  276. Meiling RL, Bouselis JG, Teteris NJ, Ullery JC, George OT (1963) Histochemical observations of a Brenner cell tumor with masculinization. Am J Obstet Gynecol 87: 463–470

    PubMed  CAS  Google Scholar 

  277. Miettinen M, Talerman A, Wahlström T, Astengo-Osuna C, Virtanen I (1988) Cellular differentiation in ovarian sex-cord-stromal and germ-cell tumors studied with antibodies to intermediate filament proteins. Am J Surg Pathol 9: 640–651

    Article  Google Scholar 

  278. Meyer-Hofmann G, Schwarzkopf H, Hartmann H (1960) Spontaneous hypoglycemia with extrapancreatic tumors. Dtsch Med Wochenschr 85: 2106–2108

    Article  PubMed  CAS  Google Scholar 

  279. Michael CA (1967) Pelvic fibroma causing recurrent attacks of hypoglycemia. J Obstet Gynaecol Br Commow 74: 301–303

    Article  CAS  Google Scholar 

  280. Miettinen M, Lehto V-P, Virtanen I (1983) Expression of intermediate filaments in normal ovaries and ovarian epithelial, sex cord-stromal, and germinal tumors. Int J Gynecol Pathol 2: 64–71

    Article  PubMed  CAS  Google Scholar 

  281. Miettinen M, Talerman A, Wahlstrom T, Astengo-Osuna C, Virtanen I (1985) Cellular differentiation in ovarian sex-cord—stromal and germ-cell tumors studied with antibodies to intermediate-filament proteins. Am J Surg Pathol 9: 640–651

    Article  PubMed  CAS  Google Scholar 

  282. Mittal KR, Blechman A, Greco MA, Alfonso F, Demopoulos R (1992) Lymphoma of ovary with stromal luteinization, presenting as secondary amenorrhea. Gynecol Oncol 45: 69–75

    Article  PubMed  CAS  Google Scholar 

  283. Miyauchi J, Yamazaki K, Kiso I, et al (1987) Bilateral ovarian hemangiomas associated with diffuse hemangio-endotheliomatosis: A case report. Acta Pathol Jpn 37: 1347–1355

    PubMed  CAS  Google Scholar 

  284. Mohabeer J, Buckley CH, Fox H (1983) An immunohis-tochemical study of the incidence and significance of human chorionic gonadotrophin synthesis by epithelial ovarian neoplasms. Gynecol Oncol 16: 78–84

    Article  PubMed  CAS  Google Scholar 

  285. Montag TW, Murphy RE, Belinson JL (1984) Virilizing malignant lipid cell tumor producing erythropoietin. Gynecol Oncol 19: 98–103

    Article  PubMed  CAS  Google Scholar 

  286. Mordel N, Margalioth EJ, Harats N, et al (1988) Concurrence of ovarian cancer and dermatomyositis. A report of two cases and literature review. J Reprod Med 33: 649–655

    PubMed  CAS  Google Scholar 

  287. Morgan DR, Wells M, MacDonald RC, Johnston D (1985) Zollinger-Ellison syndrome due to a gastrin secreting ovarian mucinous cystadenoma. Case report. Br J Obstet Gynaecol 92: 867–869

    Article  PubMed  CAS  Google Scholar 

  288. Morgello S, Schwartz E, Horwith M, et al (1988) Ectopic insulin production by a primary ovarian carcinoid. Cancer 61: 800–805

    Article  PubMed  CAS  Google Scholar 

  289. Morris J McL, Scully RE (1958) Endocrine Pathology of the Ovary. St. Louis, C.V. Mosby Co.

    Google Scholar 

  290. Morrison CW, Woodruff JD (1964) Fibrothecoma and associated ovarian stromal neoplasia. Obstet Gynecol 23: 344

    PubMed  CAS  Google Scholar 

  291. Motlik K (1966) An estrogen-producing “yellow tumour” of the ovary associated with arterial hypertension. Endokrynol Pol 17: 525–539

    PubMed  CAS  Google Scholar 

  292. Motlik K, Abrahamova J, Koutecky J, Horejsi J, Starka L (1987) Successive bilateral arrhenoblastoma. Path Res Pract 182: 453–584

    Article  Google Scholar 

  293. Motlik K, Starka L (1973) Adrenocortical tumour of the ovary. (A case report with particular stress upon morphological and biochemical findings.) Neoplasma 20: 97

    PubMed  CAS  Google Scholar 

  294. Motlik K, Stejskalova A, Stejskal J, Kobilkova J, Starka L (1988) Hilus cell tumors of the ovary. Cesk Pathol 24: 144–160

    CAS  Google Scholar 

  295. Nakashima N, Young RH, Scully RE (1984) Androgenic granulosa cell tumors of the ovary. A clinicopathological analysis of seventeen cases and review of the literature. Arch Pathol Lab Med 108: 786

    PubMed  CAS  Google Scholar 

  296. Napoli VM, Wallach H (1976) Pancytopenia associated with a granulosa-cell tumor of the ovary. Report of a case. Am J Clin Pathol 65: 344–350

    PubMed  CAS  Google Scholar 

  297. Neubecker RD, Breen JL (1962) Gynandroblastoma. A report of five cases with a discussion of the histogenesis and classification of ovarian tumors. Am J Clin Pathol 38: 60

    PubMed  CAS  Google Scholar 

  298. Neville AJ, Gilchrist KW, Davis TE (1984) The chemotherapy of granulosa cell tumors of the ovary: Experience of the Wisconsin Clinical Cancer Center. Med Pediatr Oncol 12: 397–400

    Article  PubMed  CAS  Google Scholar 

  299. Nguyen KQ, Hurst CG, Pierson DL, et al (1983) Sweet’s syndrome and ovarian carcinoma. Cutis 32: 152–154

    PubMed  CAS  Google Scholar 

  300. Nichols J, Warren JC, Mantz FA (1962) ACTH-like excretion from carcinoma of the ovary. JAMA 182: 713–718

    Article  PubMed  CAS  Google Scholar 

  301. Nieminen U, Von Numers C, Widholm O (1963) Struma ovarii. Acta Obstet Gynecol Scand 42: 399–424

    Article  Google Scholar 

  302. Niswander KR, Courey NG, Woodward T (1965) Precocious pseudopuberty caused by ovarian tumors. Obstet Gynecol 26: 381

    PubMed  CAS  Google Scholar 

  303. Nogales FF, Concha A, Plata C, Ruiz-Avila I (1993) Granulosa cell tumor of the ovary with diffuse true hepatic differentiation simulating stromal luteinization. Am J Surg Pathol 17: 85–90

    Article  PubMed  CAS  Google Scholar 

  304. Noms HJ, Taylor HB (1968) Prognosis of granulosa-theca tumors of the ovary. Cancer 21: 255

    Article  Google Scholar 

  305. Noms HJ, Taylor HB (1969) Virilization associated with cystic granulosa tumors. Obstet Gynecol 34: 629

    Google Scholar 

  306. Novak DJ, Lauchlan SC, McCawley JC, Faiman C (1970) Virilization during pregnancy. Case report and review of literature. Am J Med 49: 281–290

    Article  PubMed  CAS  Google Scholar 

  307. Novak ER (1967) Gynandroblastoma of the ovary. Review of 8 cases from the Ovarian Tumor Registry. Obstet Gynecol 30: 709

    PubMed  CAS  Google Scholar 

  308. Novak ER, Kutchmeshgi J, Mupas RS, Woodruff JD, et al (1971) Feminizing gonadal stremai tumors. Obstet Gynecol 38: 701

    PubMed  CAS  Google Scholar 

  309. Novak ER, Long JH (1965) Arrhenoblastoma of the ovary. A review of the Ovarian Tumor Registry. Am J Obstet Gynecol 92: 1082

    PubMed  CAS  Google Scholar 

  310. Novak ER, Mattingly RF (1960) Hilus cell tumor of the ovary. Obstet Gynecol 15: 425

    PubMed  CAS  Google Scholar 

  311. Nussbaum SR, Gas R, Arnold A (1990) Hypercalcemia and ectopic secretion of parathyroid hormone by an ovarian carcinoma with rearrangement of the gene for parathyroid hormone. N Engl J Med 323: 1324–1328

    Article  PubMed  CAS  Google Scholar 

  312. Ober WB, Pollak A, Gerstmann KE, Kupperman HS (1962) Krukenberg tumor with androgenic and progestational activity. Am J Obstet Gynecol 84: 739–744

    PubMed  CAS  Google Scholar 

  313. O’Hern TM, Neubecker RD (1962) Arrhenoblastoma. Obstet Gynecol 19: 758

    PubMed  Google Scholar 

  314. Okolo SO, Darley C, Melville HAH, Kirkham N (1990) Virilizing ovarian serous cystadenoma. Case report. Br J Obstet Gynecol 97: 269–271

    Article  CAS  Google Scholar 

  315. O’Neill RT, Mikuta JJ (1970) Hypoglycemia associated with serous cystadenocarcinoma of the ovary. Obstet Gynecol 35: 287–289

    PubMed  Google Scholar 

  316. Osborn RH, Yannone ME (1971) Plasma androgens in the normal and androgenic female. A review. Obstet Gynecol Surv 26: 195

    Article  Google Scholar 

  317. Palmer PE, Bogojavlensky S, Bhan AK, Scully RE (1990) Prolactinoma in wall of ovarian dermoid cyst with hyper-prolactinemia. Obstet Gynecol 75: 540–543

    PubMed  CAS  Google Scholar 

  318. Paoletti M, Pridjian G, Okagaki T, Talerman A (1987) A stremai Leydig cell tumor of the ovary occurring in a pregnant 15-year-old girl. Ultrastructural findings. Cancer 60: 2806–2810

    Article  PubMed  CAS  Google Scholar 

  319. Plotz EJ, Wiener M, Stein AA (1966) Steroid synthesis in cystadenocarcinoma of the ovaries. Am J Obstet Gynecol 94: 189–194

    PubMed  CAS  Google Scholar 

  320. Paraskevas M, Scully RE (1989) Hilus cell tumor of the ovary. A clinicopathological analysis of 12 Reinke crystal-positive and 9 crystal-negative cases. Int J Gynecol Pathol 8: 299–310

    Article  PubMed  CAS  Google Scholar 

  321. Parish JM, Lufkin EG, Lee RA, Gaffey TA (1984) Ovarian leiomyoma with hilus cell hyperplasia that caused virilization. Mayo Clinic Proc 59: 275–277

    Article  CAS  Google Scholar 

  322. Parsons V, Rigby R (1958) Cushing’s syndrome associated with adenocarcinoma of the ovary. Lancet 2: 992–994

    Article  PubMed  CAS  Google Scholar 

  323. Payne D, Muss HB, Homesley HD, Jobson VW, Baird FG (1981) Autoimmune hemolytic anemia and ovarian dermoid cysts: Case report and review of the literature. Cancer 48: 721–724

    Article  PubMed  CAS  Google Scholar 

  324. Pogliani EM, Fowst C, Maffe P, et al (1988) CNS metastasis in ovarian cancer with microangiopathic hemolytic anemia associated with diffuse intravascular coagulation. Tumor 74: 731–736

    CAS  Google Scholar 

  325. Post WD, Steele HD, Gorwill RH (1978) Mucinous cystadenoma and virilization during pregnancy. Can Med Assoc J 118: 952–953

    Google Scholar 

  326. Prat J, Bhan AK, Dickersin GR, Robboy SJ, Scully RE (1982) Hepatoid yolk sac tumor of the ovary (endodermal sinus tumor with hepatoid differentiation). A light microscopic, ultrastructural and immunohistochemical study of seven cases. Cancer 50: 2355–2368

    Article  PubMed  CAS  Google Scholar 

  327. Prat J, Scully RE (1981) Cellular fibromas and fibrosarcomas of the ovary: A comparative clinicopathologic analysis of seventeen cases. Cancer 47: 2663

    Article  PubMed  CAS  Google Scholar 

  328. Prat J, Young RH, Scully RE (1982) Ovarian Sertoli-Leydig cell tumors with heterologous elements, (ii) cartilage and skeletal muscle: A clinicopathologic analysis of twelve cases. Cancer 50: 2465

    Article  PubMed  CAS  Google Scholar 

  329. Price A, Russell P, Elliott P, Bannatyne P (1990) Composite mucinous and granulosa-cell tumor of ovary: Case report of a unique neoplasm. Int J Gynecol Pathol 9: 372–378

    Article  PubMed  CAS  Google Scholar 

  330. Primrose JN, Maloney M, Wells M, Bulgim O, Johnston D (1988) Gastrin-producing ovarian mucinous cystadenomas: A cause of the Zollinger-Ellison syndrome. Surgery 104: 830–833

    PubMed  CAS  Google Scholar 

  331. Pruett KM, Gordon AN, Estrada R, et al (1988) Small-cell carcinoma of the ovary: An aggressive epithelial cancer occurring in young patients. Gynecol Oncol 29: 365–369

    Article  PubMed  CAS  Google Scholar 

  332. Prunty FTG. (1967) Hirsutism, virilism and apparent virilism and their gonadal relationship. Part I. J Endocrinol 38: 85

    Article  PubMed  CAS  Google Scholar 

  333. Pysher TJ, Hitch DC, Krous HF (1981) Bilateral juvenile granulosa cell tumors in a 4-month ody dysmorphic infant. A clinical, histologic, and ultrastructural study. Am J Surg Pathol 5: 789

    Article  PubMed  CAS  Google Scholar 

  334. Quinn MA, Oster AO, Fortune D, Hudson B (1981) Sclerosing stremai tumor of the ovary. Case report with endocrine studies. Br J Obstet Gynaecol 88: 555–558

    Article  PubMed  CAS  Google Scholar 

  335. Raggio M, Kaplan AL, Harberg JF (1983) Recurrent ovarian fibromas with basal cell nevus syndrome (Gorlin syndrome). Obstet Gynecol 61: 95s–96s

    PubMed  CAS  Google Scholar 

  336. Ramzy I (1976) Signet-ring stremai tumor of ovary. Histochemical, light, and electron microscopic study. Cancer 38: 166–172

    Article  PubMed  CAS  Google Scholar 

  337. Reddick RL, Walton LA (1982) Sertoli-Leydig cell tumor of the ovary with teratomatous differentiation. Cancer 50: 1171–1176

    Article  PubMed  CAS  Google Scholar 

  338. Robboy SJ, Noms HJ, Scully RE (1975) Insular carcinoid primary in the ovary. A clinicopathologic analysis of 48 cases. Cancer 36: 404–418

    Article  PubMed  CAS  Google Scholar 

  339. Robboy SJ, Scully RE (1980) Strumal carcinoid of the ovary. Cancer 46: 2019–2034

    Article  PubMed  CAS  Google Scholar 

  340. Robboy SJ, Scully RE, Norris HJ (1977) Primary trabecular carcinoid of the ovary. Obstet Gynecol 49: 202–207

    PubMed  CAS  Google Scholar 

  341. Robboy SJ, Scully RE, Norris HJ (1974) Carcinoid metastatic to the ovary. A clinicopathologic analysis of 35 cases. Cancer 33: 798–811

    Article  PubMed  CAS  Google Scholar 

  342. Robinson B, Eckstein R, Stiel JN, Payne WH, Kemp J (1988) An ovarian cyst associated with virilization. Aust NZ J Med 18: 161–163

    Article  Google Scholar 

  343. Rome RM, Fortune DW, Quinn MA, Brown JB (1981) Functioning ovarian tumors in postmenopausal women. Obstet Gynecol 57: 705–710

    PubMed  CAS  Google Scholar 

  344. Rome RM, Laverty CR, Brown JB (1973) Ovarian tumours in postmenopausal women. Clinicopathological features and hormonal studies. J Obstet Gynaecol Br Commonw 80: 984–991

    Article  PubMed  CAS  Google Scholar 

  345. Roth LM, Anderson MC, Govan ADT, Langley FA, Gowing NFC, Woodcock AS (1981) Sertoli-Leydig cell tumors. A cliniclpathologic study of 34 cases. Cancer 48: 187

    Article  PubMed  CAS  Google Scholar 

  346. Roth LM, liban E, Czernobilsky B (1982) Ovarian endometrioid tumors mimicking Sertoli and Sertoli-Leydig cell tumors. Sertoliform variant of endometrioid carcinoma. Cancer 50: 1322

    Article  PubMed  CAS  Google Scholar 

  347. Roth LM, Nicholas TR, Ehrlich CE (1979) Juvenile granulosa cell tumor. A clinicopathologic study of three cases with ultrastructural observations. Cancer 44: 2194

    Article  PubMed  CAS  Google Scholar 

  348. Roth LM, Slayton RE, Brady LW, Blesdsing JA, Johnson G (1985) Retiform differentiation in ovarian Sertoli-Leydig cell tumors. A clinicopathologic study of six cases from a gynecologic oncology study group. Cancer 55: 1093

    Article  PubMed  CAS  Google Scholar 

  349. Roth LM, Sternberg WH (1973) Ovarian stromal tumors containing Leydig cells. II. Pure Leydig cell tumor, nonhilar type. Cancer 32: 952

    Article  PubMed  CAS  Google Scholar 

  350. Roth LM, Sternberg WH (1983) Partly luteinized theca cell tumor of the ovary. Cancer 51: 1697

    Article  PubMed  CAS  Google Scholar 

  351. Rubin DK, Frost JF (1963) The cytologic detection of ovarian cancer. Acta Cytol 7: 191–195

    PubMed  CAS  Google Scholar 

  352. Rutgers J, Scully RE (1986) Functioning ovarian tumors with peripheral steroid cell proliferation: A report of twenty-four cases. Int J Gynecol Pathol 5: 319–337

    Article  PubMed  CAS  Google Scholar 

  353. Ryan DE, Burkes EJ Jr (1973) The multiple basalcell nevus syndrome in a Negro family. Oral Surg 36: 831–840

    Article  PubMed  CAS  Google Scholar 

  354. Sack GH, Levin J, Bell WR (1977) Trousseau’s syndrome and other manifestations of chronic disseminated coagulopathy in patients with neoplasms: Clinical, pathophysiologic and therapeutic features. Medicine 56: 1–37

    PubMed  Google Scholar 

  355. Saitoh A, Tsutsumi Y, Osamura RY, Watanabe K (1989) Sclerosing stromal tumor of the ovary. Immunohistochemical and electron-microscopic demonstration of smoothmuscle differentiation. Arch Pathol Lab Med 113: 372–376

    PubMed  CAS  Google Scholar 

  356. Salm R (1967) Pure and mixed hilus cell tumors of ovary. Ann Roy Coll Surg Engl 41: 344

    CAS  Google Scholar 

  357. Salm R (1974) Ovarian hilus-cell tumors: their varying presentations. J Pathol 113: 117

    Article  PubMed  CAS  Google Scholar 

  358. Salomon-Bernard Y, Thibaud E, Vignai J, Musset R (1975) Tumeurs a Stroma Fonctionnel. In: Cabanne F (ed) Tumeurs de l’ovaire, Chapter IL Paris, Masson et Cie, pp 309.

    Google Scholar 

  359. Samaan NA, Smith JP, Rutledge FN, Schultz PN (1976) The significance of measurement of human placental lactogen, human chorionic gonadotropin, and carcinoembryonic antigen in patients with ovarian carcinoma. Am J Obstet Gynecol 126: 186–189

    PubMed  CAS  Google Scholar 

  360. Samanth KK, Black WC (1970) Benign ovarian stromal tumors associated with free peritoneal fluid. Am J Obstet Gynecol 107: 538

    PubMed  CAS  Google Scholar 

  361. Sasano H, Sasano N (1989) What’s new in the localization of sex steroids in the human ovary and its tumors? Pathol Res Pract 185: 942–948

    Article  PubMed  CAS  Google Scholar 

  362. Sasano H, Okamoto M, Mason JI, et al (1989) Immunohis-tochemical studies of steroidogenic enzymes (aromatase, 17-hydroxylase and cholesterol side-chain cleavage cy-tochromes P-450) in sex cord-stromal tumors of the ovary. Hum Pathol 20: 452–457

    Article  PubMed  CAS  Google Scholar 

  363. Scaling ST, Kaufman RH, Patten BM (1979) Dermatomyositis and female malignancy. Obstet Gynecol 54: 474–477

    PubMed  CAS  Google Scholar 

  364. Schnoy N (1982) Ultrastructure of a virilizing ovarian Leydig-cell tumor. Virchows Arch (Pathol Anat) 397: 17

    Article  CAS  Google Scholar 

  365. Schwartz PE, Smith JP (1976) Treatment of ovarian stromal tumors. Am J Obstet Gynecol 125: 402

    PubMed  CAS  Google Scholar 

  366. Scully RE (1953) An unusual ovarian tumor containing Leydig cells but associated with endometrial hyperplasia, in a postmenopausal woman. J Clin Endocrinol Metab 13: 1254–1263

    Article  PubMed  CAS  Google Scholar 

  367. Scully RE (1962) Androgenic lesions of the ovary. In: Grady HG, Smith DE (eds) The Ovary, Chapter 9, International Academy of Pathology Monograph No. 3. Baltimore, Williams and Wilkins, pp 143.

    Google Scholar 

  368. Scully RE (1964) Stromal luteoma of the ovary. A distinctive type of lipoid-cell tumor. Cancer 17: 769

    Article  PubMed  CAS  Google Scholar 

  369. Scully RE (1968) Sex cord-mesenchyme tumours. Pathologic classification and its relation to prognosis and treatment. In: Junqueira, AC, Gentil F (eds) Ovarian Cancer, IUCC Monograph Series, Vol IL Heidelberg, Springer-Verlag, pp 40–56.

    Chapter  Google Scholar 

  370. Scully RE (1970) Sex cord tumor with annular tubules. A distinctive ovarian tumor of the Peutz-Jeghers syndrome. Cancer 25: 1107

    Article  PubMed  CAS  Google Scholar 

  371. Scully RE (1970) Gonadoblastoma. A review of 74 cases. Cancer 25: 1340

    Article  PubMed  CAS  Google Scholar 

  372. Scully RE (1979) Tumors of the Ovary and Maldeveloped Gonads. In Atlas of Tumor Pathology, 2nd series, Fascicle No. 16, Armed Forces Institute of Pathology, Washington DC.

    Google Scholar 

  373. Scully RE (1987) Ovarian tumors with functioning stroma. In: Fox H (ed) Haines and Taylor’s Gynaecological and Obstetrical Pathology, 3rd ed. Edinburgh, Churchill Liv-ingstone, pp 724–736.

    Google Scholar 

  374. Scully RE, Aguirre P, DeLellis RA (1984) Argyrophilia, serotonin, and peptide hormones in the female genital tract and its tumors. Int J Gynecol Pathol 3: 51–70

    Article  PubMed  CAS  Google Scholar 

  375. Scully RE, Cohen RB (1964) Oxidative-enzyme activity in normal and pathologic human ovaries. Obstet Gynecol 24: 667–681

    PubMed  CAS  Google Scholar 

  376. Scully RE, Dickerson GR (1989) Letter to the editor. Int J Gynecol Pathol 8: 196

    Google Scholar 

  377. Scully RE, Morris JMcL (1957) Functioning ovarian tumors. In: Meigs J, Sturgis SH (eds) Progress in Gynecology III, Chapter 2. New York, Grune and Stratton, pp 20.

    Google Scholar 

  378. Scully RE, Richardson GS (1961) Luteinization of the stroma of metastatic cancer involving the ovary and its endocrine significance. Cancer 14: 827–840

    Article  PubMed  CAS  Google Scholar 

  379. Senekjian EK, Weiser PA, Talerman A, et al (1989) Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide in the treatment of small cell carcinoma of the ovary. Cancer 64: 1183–1187

    Article  PubMed  CAS  Google Scholar 

  380. Serment HL, Laffargue P, Piana L, Blanc B (1970) Ovarian hormone tumors of female children. Int J Gynaecol Obstet 8: 409

    Google Scholar 

  381. Serov SF, Scully RE, Sobin LH (1973) International Histological Classification of Tumours, No. 9. Histological Typing of Ovarian Tumours. Geneva, World Health Organization.

    Google Scholar 

  382. Shah KH, Steele HD (1981) Sclerosing stromal tumor of the ovary. A case report and further observations. Diagn Gynecol Obstet 3: 155–159

    PubMed  CAS  Google Scholar 

  383. Sher J, Marsh M (1963) Multilocular cystic granulosa cell tumor. Am J Clin Pathol 40: 72

    PubMed  CAS  Google Scholar 

  384. Shetty MR, Boghossian HM, Duffell D, Freel R, Gonzalez JC (1982) Tumor induced hypoglycemia. A result of ectopic insulin production. Cancer 49: 1920–1923

    Article  PubMed  CAS  Google Scholar 

  385. Shiel WC, Prete PE, Jason M, Andrews BS (1985) Palmar fasciitis and arthritis with ovarian and non-ovarian carcinomas. New syndrome. Am J Med 79: 640–644

    Article  PubMed  Google Scholar 

  386. Siegman-Igra Y, Flatau E, Deligdish L (1977) Chronic diffuse intravascular coagulation (DIC) in nonmetastatic ovarian cancer. Report of a case and review of the literature. Gynecol Oncol 5: 92–100

    Article  PubMed  CAS  Google Scholar 

  387. Silva PD, Porto M, Moyer DL, Lobo RA (1988) Clinical and ultrastructural findings of an androgenizing Krukenberg tumor in pregnancy. Obstet Gynecol 71: 432–434

    PubMed  CAS  Google Scholar 

  388. Silverberg SG (1971) Brenner tumor of the ovary: A clinicopathologic study of 60 tumors in 54 women. Cancer 28: 588–596

    Article  PubMed  CAS  Google Scholar 

  389. Simmons RL, Sciarra JJ (1967) Treatment of late recurrent granulosa cell tumors of the ovary. Surg Gynecol Obstet 124: 65

    PubMed  CAS  Google Scholar 

  390. Sjostedt S, Wahlen T (1961) Prognosis of granulosa cell tumors. Acta Obstet Gynecol Scand 40: 1

    Google Scholar 

  391. Smith JP, Rutledge F (1970) Chemotherapy in the treatment of cancer of the ovary. Am J Obstet Gynecol 107: 691

    PubMed  CAS  Google Scholar 

  392. Snider BL, Benjamin DR (1981) Eruptive keratoacanthoma with an internal malignant neoplasm. Arch Dermatol 117: 788–790

    Article  PubMed  CAS  Google Scholar 

  393. Snyder RR, Tavassoli FA (1986) Ovarian strumal carcinoid: Immunohistochemical, ultrastructural, and clinico-pathologic observations. Int J Gynecol Pathol 5: 187–201

    Article  PubMed  CAS  Google Scholar 

  394. Solh HM, Azoury RS, Najjar SS (1983) Peutz-Jeghers syndrome associated with precocious puberty. J Pediatr 103: 593–595

    Article  PubMed  CAS  Google Scholar 

  395. Solomon SD, Maurer KH (1983) Association of dermatomyositis and dysgerminoma in a 16-year-old patient. Arthritis Rheum 26: 572–573

    Article  PubMed  CAS  Google Scholar 

  396. Sotto LSJ, Postoloff AV, Carr F (1956) A case of calcified ovarian fibroma with ossification. Am J Obstet Gynecol 71: 1355

    PubMed  CAS  Google Scholar 

  397. Spadoni LR, Lindberg MC, Mottet NK, Herman WL (1965) Virilization coexisting with Krukenberg tumor during pregnancy. Am J Obstet Gynecol 92: 981–991

    PubMed  CAS  Google Scholar 

  398. Srivastava KP (1976) Hypoglycemia associated with non-pancreatic mesenchymal tumors. Int Surg 61: 282–286

    PubMed  CAS  Google Scholar 

  399. Stagno PA, Petras RE, Hart WR (1987) Strumal carcinoids of the ovary. An immunohistologic and ultrastructural study. Arch Pathol Lab Med 111: 440–446

    PubMed  CAS  Google Scholar 

  400. Stenwig JT, Hazekamp JT, Beecham JB (1979) Granulosa cell tumors of the ovary. A clinicopathological study of 118 cases with long-term follow-up. Gynecol Oncol 7: 136

    Article  PubMed  CAS  Google Scholar 

  401. Sternberg WH (1949) The morphology, endocrine function, hyperplasia and tumors of the human ovarian hilus cells. Am J Pathol 25: 493

    PubMed  CAS  Google Scholar 

  402. Sternberg WH, Dhurandhar HN (1977) Functional ovarian tumors of stromal and sex cord origin. Hum Pathol 8: 565

    Article  PubMed  CAS  Google Scholar 

  403. Sternberg WH, Roth LM (1973) Ovarian stromal tumors containing Leydig cells. 1. Stromal-Leydig cell tumor and non-neoplastic transformation of ovarian stroma to Leydig cells. Cancer 32: 940

    Article  PubMed  CAS  Google Scholar 

  404. Stewart AF, Romero R, Schwartz PE, Kohorn El, Broadus AE (1982) Hypercalcemia associated with gynecologic malignancies. Biochemical characterization. Cancer 49: 2389–2394

    Article  PubMed  CAS  Google Scholar 

  405. Stewart KR, Casey MJ, Gondos B (1981) Endodermal sinus tumor of the ovary with virilization. Light and electronmicroscopy study. Am J Surg Pathol 5: 385–391

    Article  PubMed  CAS  Google Scholar 

  406. Sugiyama M, Kohmoto Y, Miyoshi T, et al (1983) In vivo and vitro steroid biosynthesis by ovarian juvenile granulosa cell tumor of a girl with Olliers disease. Acta Gynaecol Jpn 35: 2185

    Google Scholar 

  407. Suit PF, Hart WR (1988) Sclerosing stromal tumor of the ovary. An ultrastructural study and review of the literature to evaluate hormonal function. Cleve Clin J Med 55: 189–194

    PubMed  CAS  Google Scholar 

  408. Susil BJ, Sumithran E (1987) Sarcomatous change in granulosa cell tumor. Hum Pathol 18: 397–399

    Article  PubMed  CAS  Google Scholar 

  409. Swanson PE, Dehner LP (1990) Letter to the Editor. Am J Clin Pathol 94: 805

    Google Scholar 

  410. Sweeney EC, Lee G (1979) Granulosa cell tumour of the ovary metastasizing to the heart: A light and electron microscopic study. Ir J Med Sci 148: 11–12

    Article  Google Scholar 

  411. Symonds DA, Driscoll SG (1973) An adrenal cortical rest within the fetal ovary. Report of a case. Am J Clin Pathol 60: 562

    PubMed  CAS  Google Scholar 

  412. Synder RR, Tavassoli FA (1986) Ovarian strumal carcinoid. Immunohistochemical, ultrastructural, and clinicopathologic observations. Int J Gynecol Pathol 5: 187–201

    Article  Google Scholar 

  413. Takeda A, Suzumori K, Sugimoto Y, et al (1984) Clear cell carcinoma of the ovary with colony-stimulating-factor production. Occurrence of marked granulocytosis in a patient and nude mice. Cancer 54: 1019–1023

    Article  PubMed  CAS  Google Scholar 

  414. Takeuchi H, Hamada H, Sodemoto Y, Ushigome S (1983) Juvenile granulosa cell tumor with rapid distant metastases. Acta Pathol Jpn 33: 537

    PubMed  CAS  Google Scholar 

  415. Talbott JH (1977) Acute dermatomyositis-polymyositis and malignancy. Semin Arthritis Rheum 6: 305–360

    Article  PubMed  CAS  Google Scholar 

  416. Talerman A (1987) Ovarian Sertoli-Leydig cell tumor (androblastoma) with retiform pattern: A clinicopathologic study. Cancer 60: 3056–3064

    Article  PubMed  CAS  Google Scholar 

  417. Talerman A, Haije WG (1985) Letter to the Editor. Int J Gynecol Pathol 4: 171–172

    Article  PubMed  CAS  Google Scholar 

  418. Talerman A, Hughesdon PE, Anderson MC (1982) Diffuse nonlobular ovarian androblastoma usually associated with feminization. Int J Gynecol Pathol 1: 155–171

    Article  PubMed  CAS  Google Scholar 

  419. Tamini HK, Bolen J (1984) Enchondromatosis (Ollier’s disease) and ovarian juvenile granulosa cell tumor. Cancer 53: 1605–1608

    Article  Google Scholar 

  420. Tanaka Y, Sasaki Y, Nishihira H, Izawa T, Nishi T (1992) Ovarian juvenile granulosa cell tumor associated with Maffucci’s syndrome. Am J Clin Pathol 97: 523–527

    PubMed  CAS  Google Scholar 

  421. Tang M, Liu T (1982) Ovarian sclerosing stromal tumors. Clinicopathologic study of 10 cases. Chinese Med J 95: 186–190

    CAS  Google Scholar 

  422. Targett CS (1974) Estrogen excretion in a case of theca-granulosa cell tumor. Am J Obstet Gynecol 119: 859

    PubMed  CAS  Google Scholar 

  423. Tavassoli FA, Noms HJ (1980) Sertoli tumors of the ovary. A clinicopathologic study of 28 cases with ultrastructural observations. Cancer 46: 2282

    Article  Google Scholar 

  424. Taylor HB, Norris HJ (1967) Lipid cell tumors of the ovary. Cancer 20: 1953

    Article  PubMed  CAS  Google Scholar 

  425. Teilum G (1958) Classification of testicular and ovarian androblastoma and Sertoli cell tumors. Cancer 11: 769

    Article  PubMed  CAS  Google Scholar 

  426. Teilum G (1949) Homologous ovarian and testicular tumors. III. Estrogen producing Sertoli cell tumors (androblastoma tubulare lipoides) of the human testis and ovary. J Clin Endocrinol 9: 301

    Article  CAS  Google Scholar 

  427. Teilum G (1971) Special Tumors of Ovary and Testis. Comparative Pathology and Histological Identification. Philadelphia, JB Lippincott.

    Google Scholar 

  428. Teter J, Bulsld T, Wasilewska B (1962) A virilizing adrenal rest tumor of the ovary with postmenopausal uterine hypertrophy. Bull Pol Med Sci Hist 5: 144

    Google Scholar 

  429. Tetu B, Lebel M, Camilleri J (1988) Renin-producing ovarian tumor. A case report with immunohistochemical and electron-microscopic study. Am J Surg Pathol 12: 634–640

    PubMed  CAS  Google Scholar 

  430. Tetu B, Ordonez NG, Silva EG (1986) Sertoli-Leydig cell tumor of the ovary with alpha-fetoprotein production. Arch Pathol Lab Med 110: 65–68

    PubMed  CAS  Google Scholar 

  431. Tighe JR (1961) Brenner tumours of the ovary: A clinico-pathological study. J Obstet Gynaecol Brit Commonw 68: 292–296

    Article  CAS  Google Scholar 

  432. Tiltman AJ (1985) Sclerosing stromal tumor of the ovary: Demonstration of Ligandin in three cases. Int J Gynecol Pathol 4: 362–369

    Article  PubMed  CAS  Google Scholar 

  433. Todesco S, Terribile V, Borsatti A, et al (1975) Primary aldosteronism due to a malignant ovarian tumor. J Clin Endocrinol Metab 41: 809–819

    Article  PubMed  CAS  Google Scholar 

  434. Tracy SL, Askin FB, Reddick RL, Jackson B, Kurman RJ (1985) Progesterone secreting Sertoli cell tumor of the ovary. Gynecol Oncol 22: 85–96

    Article  PubMed  CAS  Google Scholar 

  435. Tsukamoto N, Nakamura M, Ishikawa H (1976) Sclerosing stromal tumor of the ovary. Gynecol Oncol 4: 335–339

    Article  PubMed  CAS  Google Scholar 

  436. Tyler HR (1974) Paraneoplastic syndromes of nerve, muscle, and neuromuscular junction. Ann NY Acad Sci 230: 348–357

    Article  PubMed  CAS  Google Scholar 

  437. Tytle T, Rosin D (1984) Bilateral calcified ovarian fibromas. South Med J 77: 1178–1180

    Article  PubMed  CAS  Google Scholar 

  438. Ueda G, Nobuaki H, Hayakawa K, et al (1972) Clinical histochemical and biochemical studies of an ovarian dysgerminoma with trophoblasts and Leydig cells. Am J Obstet Gynecol 114: 748–754

    PubMed  CAS  Google Scholar 

  439. Ueda G, Sato Y, Yamasaki M, et al (1978) Strumal carcinoid of the ovary. Histological, ultrastructural and immunohistological studies with anti-human thyroglobulin. Gynecol Oncol 6: 411–419

    Article  PubMed  CAS  Google Scholar 

  440. Ulbright TM, Roth LM, Ehrlich CE (1982) Ovarian strumal carcinoid. An immunocytochemical and ultrastructural study of two cases. Am J Clin Path 77: 622–631

    PubMed  CAS  Google Scholar 

  441. Ulbright TM, Roth LM, Stehman FB, Talerman A, Senekjian EK (1987) Poorly differentiated (small cell) carcinoma of the ovary in young women: Evidence supporting a germ cell origin. Hum Pathol 18: 175–184

    Article  PubMed  CAS  Google Scholar 

  442. Vaitukaitis JL (1974) Human chorionic gonadotropin as a tumor marker. Ann Clin Lab Sci 4: 276–280

    PubMed  CAS  Google Scholar 

  443. Vassal G, Flamant F, Caillaud JM, et al (1988) Juvenile granulosa cell tumor of the ovary in children: A clinical study of 15 cases. J Clin Oncol 6: 990–995

    PubMed  CAS  Google Scholar 

  444. Vaz RM, Turner C (1986) Ollier disease (Enchondromatosis) associated with ovarian juvenile granulosa cell tumor and precocious puberty. J Pediatr 108: 945–947

    Article  PubMed  CAS  Google Scholar 

  445. Velasco-Oses A, Alonso-Alvaro A, Blanco-Pozo A, et al (1988) Olliers disease associated with ovarian juvenile granulosa cell tumor. Cancer 62: 222–225

    Article  PubMed  CAS  Google Scholar 

  446. Verducci MA, Malkasian GD, Friedman SJ, Winkelmann RK (1984) Gynecologic carcinoma associated with derma-tomyositis-polymyositis. Obstet Gynecol 64: 695–698

    PubMed  CAS  Google Scholar 

  447. Verhoeven ATM, Mastboom JL, Van Leusden HAIM, Van DerVelden WHM (1973) Virilization in pregnancy coexisting with an (ovarian) mucinous cystadenoma: A case report and review of virilizing ovarian tumors in pregnancy. Obstet Gynec Surv 28: 597–622

    Article  CAS  Google Scholar 

  448. Vicens E, Martinez-Mora J, Potau N, Sans M, Boix-Ochoa J (1980) Masculinization of a female fetus by Krukenberg tumor during pregnancy. J Pediatr Surg 15: 188–190

    Article  PubMed  CAS  Google Scholar 

  449. von dem Borne AEGK, van Oers RHJ, Wiersinga WM, et al (1990) Complete remission of autoimmune thrombocytopenia after extirpation of a benign adenofibroma of the ovary. Br J Rheumatol 74: 119–120

    Google Scholar 

  450. Waxman M, Damjanov I, Alpert L, Sardinsky T (1981) Composite mucinous ovarian neoplasms associated with Sertoli-Leydig and carcinoid tumors. Cancer 47: 2044

    Article  PubMed  CAS  Google Scholar 

  451. Waxman M, Vuletin JC, Urcuyo R, Belling CG (1979) Ovarian low-grade stromal sarcoma with thecomatous features. A critical reappraisal of the so-called “malignant thecoma.” Cancer 44: 2206

    PubMed  CAS  Google Scholar 

  452. Woodruff JD, Rauh JT, Markley RL (1966) Ovarian Struma. Obstet Gynecol 27: 194–201

    PubMed  CAS  Google Scholar 

  453. Woodruff JD, Williams TJ, Goldberg B, Lawterbach M, Preece E (1973) Hormonal activity of the common ovarian neoplasms. Am J Obstet Gynecol 87: 679–695.

    Google Scholar 

  454. Yaker A, Benirschke K (1975) A ten year study of ovarian tumors. Virchows Arch A Path Anat Histol 366: 275–286

    Article  CAS  Google Scholar 

  455. Yeh E, Meade RC, Ruetz PP (1973) Radionuclide study of struma ovarii. J Nucl Med 14: 118–121

    PubMed  CAS  Google Scholar 

  456. Young RH, Dickersin GR, Scully RE (1983) A distinctive ovarian sex cord-stromal tumor causing sexual precocity in the Peutz-Jeghers syndrome. Am J Surg Pathol 7: 223

    Google Scholar 

  457. Young RH, Dickersin GR, Scully RE (1984) Juvenile granulosa cell tumor of the ovary. A clinicopathologic analysis of 125 cases. Am J Surg Pathol 8: 575

    Article  PubMed  CAS  Google Scholar 

  458. Young RH, Dudley AG, Scully RE (1984) Granulosa cell, Sertoli-Leydig cell and unclassified sex cord-stromal tumors associated with pregnancy. A clinicopathological analysis of thirty-six cases. Gynecol Oncol 18: 181

    Article  PubMed  CAS  Google Scholar 

  459. Young RH, Oliva E, Scully RE (in press) Lutenized adult granulosa cell tumors of the ovary: A report of four cases. Int J Gynecol Pathol.

    Google Scholar 

  460. Young RH, Oliva E, Scully RE Small cell carcinoma of the ovary, hypercalcemia type. A clinico pathological analysis of 150 cases. Submitted.

    Google Scholar 

  461. Young RH, Perez-Atayde AR, Scully RE (1984) Ovarian Sertoli-Leydig cell tumor with retiform and heterologous components. Report of a case with hepatocytic differentiation and elevated serum alpha-fetoprotein. Am J Surg Pathol 8: 709

    Article  PubMed  CAS  Google Scholar 

  462. Young RH, Prat J, Scully RE (1982) Ovarian endometrioid carcinomas resembling sex cord-stromal tumors. A clinicopathological analysis of 13 cases. Am J Surg Pathol 6: 513–522

    Article  PubMed  CAS  Google Scholar 

  463. Young RH, Prat J, Scully RE (1982) Ovarian Sertoli-Leydig cell tumors with heterologous elements, (i) Gastrointestinal epithelium and carcinoid: A clinicopathologic analysis of thirty-six cases. Cancer 50: 2448–2456

    Article  PubMed  CAS  Google Scholar 

  464. Young RH, Prat J, Scully RE (1983) Endometrioid stromal sarcomas of the ovary. A clinicopathological analysis of twenty-three cases. Cancer 53: 1143

    Article  Google Scholar 

  465. Young RH, Scully RE (1991) Malignant melanoma metastatic to the ovary. A clinicopathologic analysis of 20 cases. Am J Surg Pathol 15: 849–860

    Article  PubMed  CAS  Google Scholar 

  466. Young RH, Scully RE (1992) Ovarian sex cord-stromal tumors. Recent progress. Int J Gynecol Pathol 1: 101

    Article  Google Scholar 

  467. Young RH, Scully RE (1983) Ovarian stromal tumors with minor sex cord elements: A report of seven cases. Int J Gynecol Pathol 2: 227

    Article  PubMed  CAS  Google Scholar 

  468. Young RH, Scully RE (1983) Ovarian sex cord-stromal tumors with bizarre nuclei. A clinicopathologic analysis of seventeen cases. Int J Gynecol Pathol 1: 325

    Article  PubMed  CAS  Google Scholar 

  469. Young RH, Scully RE (1983) Ovarian Sertoli-Leydig cell tumors with a retiform pattern: A problem in histopathologic diagnosis. A report of 25 cases. Am J Surg Pathol 77: 755

    Google Scholar 

  470. Young RH, Scully RE (1984) Ovarian Sertoli cell tumors. A report of ten cases. Int J Gynecol Pathol 2: 349

    Article  PubMed  CAS  Google Scholar 

  471. Young RH, Scully RE (1984) Ovarian sex cord-stromal tumors: Recent advances and current status. Clin Obstet Gynecol 11: 93

    CAS  Google Scholar 

  472. Young RH, Scully RE (1984) Fibromatosis and massive edema of the ovary, possibly related entities. A report of 14 cases of fibromatosis and 11 cases of massive edema. Int J Gynecol Pathol 3: 153

    Article  PubMed  CAS  Google Scholar 

  473. Young RH, Scully RE (1988) Ovarian sex cord-stromal tumors: Problems in differential diagnosis. Pathol Annu 23(PT I): 237–296.

    PubMed  Google Scholar 

  474. Young RH, Scully RE (1987) Ovarian steroid cell tumors associated with Cushing’s syndrome. A report of three cases. Int J Gynecol Pathol 6: 40–48

    Article  PubMed  CAS  Google Scholar 

  475. Young RH, Scully RE (1989) Alveolar rhabdomyosarcoma metastatic to the ovary. A report of two cases and discussion of the differential diagnosis of small cell malignant tumors of the ovary. Cancer 64: 899–904

    Article  PubMed  CAS  Google Scholar 

  476. Young RH, Scully RE (1990) Sarcomas metastatic to the ovary. A report of 21 cases. Int J Gynecol Pathol 9: 231–252

    Article  PubMed  CAS  Google Scholar 

  477. Young RH, Scully RE (1984) Well-differentiated ovarian Sertoli-Leydig cell tumors. A clinicopathological analysis of 23 cases. Int J Gynecol Pathol 3: 277

    Article  PubMed  CAS  Google Scholar 

  478. Young RH, Scully RE (1985) Ovarian Sertoli-Leydig cell tumors. A clinicopathological analysis of 207 cases. Am J Surg Pathol 9: 543–569

    Article  PubMed  CAS  Google Scholar 

  479. Young RH, Welch WR, Dickersin GR, Scully RE (1982) Ovarian sex cord tumor with annular tubules: Review of 74 cases including 27 with Peutz-Jeghers syndrome and 4 with adenoma malignum of the cervix. Cancer 50: 1384

    Article  PubMed  CAS  Google Scholar 

  480. Yuen BH, Robertson I, Clement PB, Mincey EK (1982) Sclerosing stromal tumor of the ovary. Obstet Gynecol 60: 252–256

    Google Scholar 

  481. Zaloudek C, Noms HJ (1982) Granulosa tumors of the ovary in children. A clinical and pathologic study of 32 cases. Am J Surg Pathol 6: 503

    Article  PubMed  CAS  Google Scholar 

  482. Zaloudek C, Noms HJ (1984) Sertoli-Leydig tumors of the ovary. A clinicopathologic study of 64 intermediate and poorly differentiated neoplasms. Am J Surg Pathol 8: 405–418

    Article  PubMed  CAS  Google Scholar 

  483. Zaloudek CJ, Tavassoli FA, Noms HJ (1981) Dysgerminoma with syncytiotrophoblastic giant cells. A histologically and clinically distinctive subtype of dysgerminoma. Am J Surg Pathol 5: 361–367

    Article  PubMed  CAS  Google Scholar 

  484. Zhang J, Young RH, Arseneau J, Scully RE (1982) Ovarian stromal tumors containing lutein or Leydig cells (luteinized thecomas and stromal Leydig cell tumors). A clinicopathological analysis of fifty cases. Int J Gynecol Pathol 1: 270

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. Robert H. Young M.D., F.R.C. Path.
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  2. Robert E. Scully M.D.
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Editors and Affiliations

  1. Departments of Gynecology and Obstetrics and Pathology, The Johns Hopkins Hospital and The Johns Hopkins University, School of Medicine, Baltimore, MD, 21287, USA

    Robert J. Kurman M.D.

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Young, R.H., Scully, R.E. (1994). Sex Cord-Stromal, Steroid Cell, and Other Ovarian Tumors with Endocrine, Paraendocrine, and Paraneoplastic Manifestations. In: Kurman, R.J. (eds) Blaustein’s Pathology of the Female Genital Tract. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3889-6_19

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