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Pulmonary Malignancies: Pathophysiology and Treatment

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Principles and Practice of Geriatric Surgery

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Abstract

Lung cancer is a highly lethal neoplasm, with the worldwide incidence expected to have exceeded one million cases annually by the start of this millennium. Presently, it is the most frequent cause of cancer-related death in both men and women in the United States. Approximately 178,100 new lung cancer cases were diagnosed in 1997, and 160,400 deaths will be attributed to this disease.1 Metastatic disease involving the lungs is observed in a vast number of additional malignancies, including those of gastrointestinal, genitourinary, breast, and mesenchymal origin; in some cases (particularly soft tissue sarcomas), pulmonary disease represents the sole site of distant metastases. This chapter focuses on current aspects of the pathophysiology and treatment of primary and metastatic tumors involving the lungs.

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  1. David S. Schrump
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Editors and Affiliations

  1. Department of Surgery, Yale University School of Medicine, New Haven, CT, 06520, USA

    Ronnie A. Rosenthal MD (Associate Professor, Chief, Surgical Service) (Associate Professor, Chief, Surgical Service)

  2. Department of Veterans Affairs, VA Connecticut Healthcare System, West Haven, 06516, CT, USA

    Ronnie A. Rosenthal MD (Associate Professor, Chief, Surgical Service) (Associate Professor, Chief, Surgical Service)

  3. Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, 10461, NY, USA

    Michael E. Zenilman MD (Associate Professor and Vice-Chairman, Chief of Surgery) (Associate Professor and Vice-Chairman, Chief of Surgery)

  4. Jack D. Weiler Hospital of the Albert Einstein College of Medicine, Bronx, 10461, NY, USA

    Michael E. Zenilman MD (Associate Professor and Vice-Chairman, Chief of Surgery) (Associate Professor and Vice-Chairman, Chief of Surgery)

  5. Wyoming Valley Surgical Associates, Kingston, 18704, PA, USA

    Mark R. Katlic M.D. (Chief of Thoracic Surgery) (Chief of Thoracic Surgery)

  6. Wyoming Valley Healthcare System, Wilkes-Barre, 18702, PA, USA

    Mark R. Katlic M.D. (Chief of Thoracic Surgery) (Chief of Thoracic Surgery)

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Schrump, D.S. (2001). Pulmonary Malignancies: Pathophysiology and Treatment. In: Rosenthal, R.A., Zenilman, M.E., Katlic, M.R. (eds) Principles and Practice of Geriatric Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3432-4_29

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