Abstract
Phencyclidine (PCP) is the most common member of the “dissociatives.” The dissociatives constitute an entirely synthetic class of drugs that act at multiple receptor sites. They act as agonists or antagonists at cholinergic, dopaminergic, noradrenergic, opioid, serotonergic, sigma, and NDMA (N-methyl-D-aspartate) -high-affinity and -low-affinity receptor sites. As a result, dissociatives can mimic atropinic, GABAminergic, opioid, psychedelic, and sympathomimetic drugs. Since the drugs in this class are active in powdered, crystalline, suspended, and volatile forms, they can be ingested, snorted, injected, smoked, or inhaled (Giannini, 1987b).
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Giannini, A.J. (1998). Phencyclidine. In: Tarter, R.E., Ammerman, R.T., Ott, P.J. (eds) Handbook of Substance Abuse. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2913-9_36
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DOI: https://doi.org/10.1007/978-1-4757-2913-9_36
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