Abstract
Our development work focuses on the use of biodegradable, biocompatible polymeric alloys in the production of bone repair plates. The basic premise proposed is that inclusion of a crosslinkable polymer (PPF) in an alloy composed primarily of PLA, heretofore the biopolymeric plate standard, will improve the dimensional stability of a PLA-only plate, while maintaining acceptable mechanical characteristics. Thus, our work has been to focus on making plate specimens and characterizing, in comparative fashion, the mechanical properties. Feasibility was assessed via the demonstration of dimensional stability and resistance to bending. Our initial work detailed our preparation of alloy specimens and their mechanical (primarily tensile) testing. Additional work on these preparations has included PLA-only specimens and additional mechanical (primarily bending) tests. Our results now tentatively demonstrate that a cross-linkable PLA/PPF alloy does not have superior dimensional stability. Some restrictions in strength have been noted also, but it is the attempt to balance dimensional characteristics with strength that guides current work.
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Gresser, J.D., Trantolo, D.J., Wise, D.L., Altobelli, D.E., Yaszemski, M.J., Wnek, G.E. (1996). Biopolymer Alloy for Surgical Plates. In: Wise, D.L., Trantolo, D.J., Altobelli, D.E., Yaszemski, M.J., Gresser, J.D. (eds) Human Biomaterials Applications. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4757-2487-5_5
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DOI: https://doi.org/10.1007/978-1-4757-2487-5_5
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