Abstract
Critical limb ischemia (CLI) is the term used to describe chronic ischemia which is of a severity to endanger the whole or part of the leg. It is generally caused by advanced atherosclerotic peripheral vascular disease producing an occlusion of a large artery or arteries in the leg. The hemodynamic consequences are increased resistance at the proximal obstruction with a reduction in distal perfusion pressure and blood flow to the peripheral circulation (1).
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Hillier, C., Sayers, R.D., Watt, P.A.C., Bell, P.R.F., Thurston, H. (1994). Effect of Chronic Ischemia on Human Small Arteries. In: Halpern, W., Bevan, J., Brayden, J., Dustan, H., Nelson, M., Osol, G. (eds) The Resistance Arteries. Experimental Biology and Medicine, vol 26. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4757-2296-3_33
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DOI: https://doi.org/10.1007/978-1-4757-2296-3_33
Publisher Name: Humana Press, Totowa, NJ
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