Lenticular Senescence and the Retina

Weale, Robert

doi:10.1007/978-1-4757-2131-7_8

Robert Weale⁵

Part of the book series: Perspectives in Vision Research ((PIVR))

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Abstract

Ever since the time of Helmholtz, research workers have concerned themselves with why and how presbyopia occurs (Bito, 1988; Brückner, 1959). However, the matter has only rarely been approached from an evolutionary point of view (cf. Bito and Miranda, 1987). The outstanding question in this context is not so much why accommodation is lost in midlife as why it is well over 10 D in the very young. In what circumstances does anyone have to form detailed retinal images of objects a mere 8 or 10 cm from the eyes?

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References

Bito, L. Z., 1988, Presbyopia, Arch. Ophthalmol. 106:1526–1527.
Article PubMed CAS Google Scholar
Bito, L. Z., and Miranda, O. C., 1987, Presbyopia, the need for a closer look, in: Presbyopia (L. Stark and G. Obrecht, eds.), Fairchild Publications, New York, pp. 411–429.
Google Scholar
Brückner, R., 1959, Über Methoden longitudinaler Alterns-forschung am Auge, Ophthalmologica 138:59–75.
Article PubMed Google Scholar
Brückner, R., Batschelet, E., and Hugenschmidt, F., 1987, The Basel longitudinal study on aging (1955–1978), Docum. Ophthalmol. 64:235–310.
Article Google Scholar
Duane, A., 1912, Normal values of the accommodation at all ages, JAMA. 59:1010–1013.
Article Google Scholar
Feeney-Burns, L., Hildebrand, E. S., and Eldridge, S., 1984, Aging human RPE: Morphometric analysis of macular, equatorial and peripheral cells, Invest. Ophthalmol. Vis. Sci. 25:195–200.
PubMed CAS Google Scholar
Harman, D., 1985, Role of free radicals in aging and disease, in: Relations between Normal Aging and Disease (A. H. Johnson, ed.), Raven Press, New York, pp. 45–84.
Google Scholar
Kay, C. D., and Morrison, J. D., 1987, A quantitative investigation into the effects of pupil diameter and defocus on contrast sensitivity for an extended range of spatial frequencies in natural and homatropinized eyes, Ophthalmol. Physiol. Opt. 7:21–30.
Article CAS Google Scholar
Keunen, J. E. E., Van Norren, D., and Van Meel, G., 1987, Density of foveal cone pigments at older age, Invest. Ophthalmol. Vis. Sci. 28:985–991.
PubMed CAS Google Scholar
Kilbride, P. E., Hutman, L. P., Fishman, M., and Read, J. S., 1986, Foveal cone pigment density difference in the aging human eye, Vision Res. 26:321–325.
Article PubMed CAS Google Scholar
Lestienne, R., 1988, On the thermodynamical and biological interpretation of the Gompertzian mortality rate distribution, Mech. Ageing Dev. 42:197–214.
Article PubMed CAS Google Scholar
McBrien, N. A., and Millodot, M., 1986, Amplitude of accommodation and refractive error, Invest. Ophthalmol. Vis. Sci. 27:1187–1190.
PubMed CAS Google Scholar
Sloane, M. E., Owsley, C., and Alvarez, S. L., 1988, Aging, senile miosis and spatial contrast sensitivity at low luminance, Vision Res. 28:1235–1246.
Article PubMed CAS Google Scholar
Sohal, R. S., and Wolfe, L. S., 1986, Lipofuscin: Characteristics and significance, Prog. Brain Res. 70:171–183.
Article PubMed CAS Google Scholar
Warner, H. R., Butler, R. N., Sprott, R. L., and Schneider, E. L. (eds.), 1987, Modern Biological Theories of Aging, Raven Press, New York.
Google Scholar
Weale, R. A., 1963, New light on old eyes, Nature 198:944–946.
Article PubMed CAS Google Scholar
Weale, R. A., 1982, A Biography of the Eye—Development, Growth, Age, H. K. Lewis, London.
Google Scholar
Weale, R. A., 1988a, Age and the transmittance of the human crystalline lens, J. Physiol. (Lond.) 395:577–587.
CAS Google Scholar
Weale, R. A., 1988b, The senescent lens and the retinal pigment epithelium, Eye 2:157S–163S.
Article Google Scholar
Weale, R. A., 1990, Evolution, age, and ocular focus, Mech. Aging Dev. 53:85–89.
Article PubMed CAS Google Scholar
Weiter, J. J., Delori, F. C., Wing, G. L., and Fitch, K. A., 1986, Retinal pigment epithelium lipofuscin and melanin and choroidal melanin in human eyes, Invest. Ophthalmol. Vis. Sci. 27:145–152.
PubMed CAS Google Scholar
Wing, G. L., Blanchard, G. C., and Weiter, J. J., 1978, The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium, Invest. Ophthalmol. Vis. Sci. 17:601–607.
PubMed CAS Google Scholar

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Authors and Affiliations

Age Concern Institute of Gerontology., King’s College London, University of London, London, SE1 8TX, Great Britain
Robert Weale

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Robert Weale
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Essilor, Creteil, France
Gérard Obrecht
University of California, Berkeley, Berkeley, California, USA
Lawrence W. Stark

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Weale, R. (1991). Lenticular Senescence and the Retina. In: Obrecht, G., Stark, L.W. (eds) Presbyopia Research. Perspectives in Vision Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2131-7_8

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DOI: https://doi.org/10.1007/978-1-4757-2131-7_8
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4419-3217-4
Online ISBN: 978-1-4757-2131-7
eBook Packages: Springer Book Archive

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