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Dietary ω3 and ω6 Fatty Acids

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Abstract

A trial of n−3 polyunsaturated fatty acids in the treatment of multiple sclerosis has been conducted over a 5-year period. 312 ambulant patients with acute remitting disease were randomly allocated to treatment and placebo controlled groups. Both were given dietary advice to increase the intake of n−6 polyunsaturated fatty acids and the treatment group in addition received capsules containing n−3 polyunsaturated fatty acids. The results showed no significant difference at the usual 95% confidence level, but there was a trend in favour of the n−3 treated group in all parameters examined including rate of deterioration, frequency and severity of attacks and number of patients improving or remaining unchanged during the course of the trial.

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Author information

Authors and Affiliations

  1. Newcastel upon Tyne, UK

    D. Bates, J. French, S. Nightindale & D. Shaw

  2. Belfast, UK

    S. Hawkins & H. Millar

  3. London, UK

    M. Sidey, A. Smith, R. Thompson & K. Zilka

  4. Oxford, UK

    M. Gale & H. Sinclair

  5. University of Florida, College of Veterinary Medicine, Gainesville, Florida, USA

    J. E. Bauer, P. Schenck & C. H. Beauchamp

  6. Laboratory of Clinical Biochemistry, University of Bergen, Bergen, Norway

    R. K. Berge & A. Aarsland

  7. Adelaide Hospital, Dublin, Ireland

    R. Clarke, A. Tobin, C. O’Morain & I. Graham

  8. Department of Nutritional Sciences, University of Toronto, Toronto, Canada

    S. C. Cunnane, T. M. S. Wolever, J. K. Armstrong & D. J. A. Jenkins

  9. Norsk Hydro Research Centre, Porsgrunn, Norway

    Knut H. Dahl, G. Øi & H. E. Krokan

  10. Laboratory of Nutrition, Catholic University of Leuven, Leuven, Belgium

    R. De Schrijver

  11. INSERM U.58, Montpellier, France

    B. Descomps, S. El Boustani, L. Monnier, F. Mendy & A. Crastes de Paulet

  12. Laboratoire de Biochemie A et Service des Maladies Metaboliques et Endocriniennes du CHR de Montpellier, Montpellier, France

    B. Descomps, S. El Boustani, L. Monnier, F. Mendy & A. Crastes de Paulet

  13. Beilinson Medical Center, Petah Tiqva, Israel

    P. Green, J. Fuchs, P. Budowski, Y. Lurie, I. Beigel, J. Agmon, L. Leibovici, R. Mamet & N. Schoenfeld

  14. Department of Biochemistry, Limburg University, Maastricht, The Netherlands

    G. Hornstra

  15. Department of Human Biology, Limburg University, Maastricht, The Netherlands

    R. van Houwelingen

  16. Manitoba Institute of Cell Biology, Winnipeg, Canada

    J. Gerrard

  17. Department of Gynaecology and Obstetrics, Academic Hospital Groningen, The Netherlands

    H. Huisjes

  18. Institute of Pharmacological Sciences and Grossi-Paoletti Center for the Study of Hyperlipidemias, University of Milan, Milan, Italy

    L. Medini, S. Colli, E. Tremoli & C. Galli

  19. Institute of Pharmacological Sciences, University of Milan, Milan, Italy

    C. Galli, C. Mosconi, M. Blasevich & M. Gianfranceschi

  20. Miami Valley Laboratories, University of California at Santa Cruz, Los Angeles and San Francisco; The Proctor and Gamble Co., USA

    D. L. Puppione, R. J. Jandacek, S. T. Kunitake & D. P. Costa

  21. Federal Research Centre of Nutrition, Karlsruhe, Germany

    H. W. Renner

  22. Andreas Gruentzig Cardiovascular Center, Clinical Research Facility, and Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, USA

    D. S. Sgoutas, J. A. Hearn, K. A. Robinson, S. B. King & G. S. Roubin

  23. ENRECO/Essential Nutrient Research Company, Manitowoc, USA

    Paul A. Stitt

  24. Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA, USA

    B. H. Weiner

Authors
  1. D. Bates
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  2. J. French
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  3. S. Nightindale
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  4. D. Shaw
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  5. S. Hawkins
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  6. H. Millar
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  7. M. Sidey
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  8. A. Smith
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  9. R. Thompson
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  10. K. Zilka
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  11. M. Gale
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  12. H. Sinclair
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  13. J. E. Bauer
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  14. P. Schenck
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  15. C. H. Beauchamp
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  16. R. K. Berge
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  17. A. Aarsland
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  18. R. Clarke
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  19. A. Tobin
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  20. C. O’Morain
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  21. I. Graham
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  22. S. C. Cunnane
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  23. T. M. S. Wolever
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  24. J. K. Armstrong
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  25. D. J. A. Jenkins
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  26. Knut H. Dahl
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  27. G. Øi
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  28. H. E. Krokan
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  29. R. De Schrijver
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  30. B. Descomps
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  31. S. El Boustani
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  32. L. Monnier
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  33. F. Mendy
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  34. A. Crastes de Paulet
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  35. P. Green
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  36. J. Fuchs
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  37. P. Budowski
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  38. Y. Lurie
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  39. I. Beigel
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  40. J. Agmon
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  41. L. Leibovici
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  42. R. Mamet
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  43. N. Schoenfeld
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  44. G. Hornstra
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  45. R. van Houwelingen
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  46. J. Gerrard
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  47. H. Huisjes
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  48. L. Medini
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  49. S. Colli
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  50. E. Tremoli
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  51. C. Galli
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  52. C. Mosconi
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  53. M. Blasevich
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  54. M. Gianfranceschi
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  55. D. L. Puppione
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  56. R. J. Jandacek
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  57. S. T. Kunitake
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  58. D. P. Costa
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  59. H. W. Renner
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  60. D. S. Sgoutas
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  61. J. A. Hearn
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  62. K. A. Robinson
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  63. S. B. King
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  64. G. S. Roubin
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  65. Paul A. Stitt
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  66. B. H. Weiner
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Editor information

Editors and Affiliations

  1. Institute of Pharmacological Sciences, University of Milan, Milan, Italy

    Claudio Galli

  2. ILSI Research Foundation, Washington, D.C., USA

    Artemis P. Simopoulos

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© 1989 Springer Science+Business Media New York

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Bates, D. et al. (1989). Posters. In: Galli, C., Simopoulos, A.P. (eds) Dietary ω3 and ω6 Fatty Acids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2043-3_41

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  • DOI: https://doi.org/10.1007/978-1-4757-2043-3_41

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-2045-7

  • Online ISBN: 978-1-4757-2043-3

  • eBook Packages: Springer Book Archive

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