Abstract
The (n−6)-fatty acids appear to be essential dietary components for mammals and birds (Holman, 1971; Mead and Fulco, 1976), whereas their nutritive importance in fish (Greene and Selvivonchick, 1987) and insect nutrition (de Renobales et al., 1987) are not yet clear. Some insects seem to be able to grow and develop without any polyunsaturated fatty acids’(Sohal et al., 1984; Rapport et al., 1984).
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References
Abraham, W., Wertz, P.W., and Downing, D.T, 1985, Linoleate-rich acylglucos•.-lceramides of pig epidermis. Structure detenmrl tion by proton magnetic resonance. J. -d Res., G6: 76.
Basnayake, V., and Sinclair, H M 1956, The et deficiency essential fatty acids anon the skin Kcal Problems fr ds G. Pop ak and F,m, eds., Butterworth Scientific Publisher, London.
Bowser, P.A., Nugteren, D.H., White, R.J., Houtsmuller, U.M.T., and Prottey, C., 1985, Identification, isolation and characterization of epidermal lipids containg linoleic acid, Biochim. Biophys. Acta 834: 419.
Bowser, P.A., and White, R.J., 1985, Isolation, barrier properties and lipid analysis of stratum compactum, a discrete region of stratum corneum, Brit. J. Dermatol. 112: 1.
Burr, G.O., and Burr, M.M., 1929, A new deficiency disease produced by rigid exclusion of fat from the diet, J. Biol. Chem. 82: 345.
Burr, G.O., and Burr, M.M., 1930, On the nature and role of the fatty acids essential in nutrition, J. Biol. Chem. 86: 587.
Cox, P., and Squier, C.A., 1986, Variations in lipids in different layers of porcine epidermis, J. Invest. Dermatol. 87: 741.
Renobales, M., Cripps, C., Stanley-Samuelson, D.W., Jurenka, R.A., and Blomquist, G.J., 1987, Biosynthesis of linoleic acid in insects, Trends Biochem. Sci. 12: 364.
Elias, P.M., 1981, Lipids and the epidermal permeability barrier, Arch. Dermatol. Res. 270: 95.
Elias, P.M., 1983, Epidermal lipides, barrier function, and desquamation, J. Invest. Dermatol. 80: 44.
Elias, P.M., 1985, The essential fatty acid deficient rodent - evidence for a direct role of intercellular lipid in barrier function, in: “Models in Dermatology” vol. 1, H.I.Maibach and N.J.Lowe, eds., Karger, Basel.
Elias, P.M., Brown, B.E., and Ziboh, V.A., 1980, The permeability barrier in essential fatty acid deficiency. Evidence for a direct role for linoleic acid in barrier function. J. Invest. Dermatol. 74: 230.
Elias, P.M., Menon, G.K., Grayson, S., Brown, B.E., and Rehfeld, S.J., 1987, Avian sebokeratinocytes and marine mammal lipokeratinocytes: structural, lipid biochemical, and functional considerations, Am. J. Anatomy 180: 161.
Elliott, W.J., Morrison, A.R., Sprecher, H.W., and Needleman, P., 1985a, The metabolic transformations of columbinic acid and the effect of topical application of the major metabolites on rat skin, J. Biol. Chem. 260: 987.
Elliott, W.J., Sprecher, H., and Needleman, P., 1985b, Physiologic effects of columbinic acid and its metabolites on rat skin. Biochim. Biophys. Acta 835: 158.
Friberg, S.E., and Osborne, D.W., 1985, Small angle X-ray diffraction patterns of stratum corneum and a model structure for its lipids, J. Dispersion Sci. Technol. 6: 485.
Golden, G.M., Guzek, D.B., Kennedy, A.H., McKnie, J.E., and Potts, R. O., 1987, Stratum corneum lipid phase transitions and water barrier properties, Biochemistry 26: 2382.
Gray, G.M., White, R.J., and Majer, J.R., 1978, 1-(3“-O-acyl)-ßglucosyl-N-dihydroxypentatriacontadienoylsphingosine, a major component of the glucosylceramides of pig and human epidermis, Biochim. Biophys. Acta 528: 127.
Greene, D.H.S., and Selivonchick, D.P., 1987, Lipid metabolism in fish, Prog. Lipid Res. 26: 53.
Gurr, M.I., 1984, “Role of Fat in Food and Nutrition”, Elsevier Appl. Sci. Publ., London.
Hammarlund, K., Nilsson, G.E., Oberg, P.A., and Sedin, G., 1977, Transepidermal water loss in newborn infants. Relation to ambient humidity and site of measurement and estimation of total transepidermal water loss. Acta Padiatr. Scand. 66: 553.
Hammarlund, K., Strömberg, B., and Sedin, G., 1986, Heat loss from the skin of preterm and fullterm newborn infants during the first weeks after birth, Biol. Neonate 50: 1.
Hansen, H.S., 1986, The essential nature of linoleic acid in mammals, Trends Biochem. Sci. 11: 263.
Hansen, H.S., and Jensen, B., 1983, Urinary prostaglandin E2 and vasopressin excretion in essential fatty acid-deficient rats: effect of linolenic acid supplementation, Lipids 18: 682.
Hansen, H.S., and Jensen, B., 1985, Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and a-linolenate, Biochim. Biophys. Acta 834: 357.
Hansen, H.S., and Jensen, B., 1987, Why is linoleic acid essential ? in: “Proc. AOCS Short Course on Polyunsaturated Fatty Acids and Eicosanoids”, W.E.M.Lands, ed., American Oil Chemists“ Society, Champaign, Illinois.
Hansen, H.S., Jensen, B., and von Wettstein-Knowles, P., 1986, Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats, Biochim. Biophys. Acta 878: 284.
Hartop, P.J., and Prottey, C., 1976, Changes in transepidermal water loss and the composition of epidermal lecithin after applications of pure fatty acid triglycerides to the skin of essential fatty acid-deficient rats, Br. J. Dermatol. 95: 255.
Holman, R.T., 1971, Essential fatty acid deficiency, Prog. Chem. Fats Lipids9: 275.
Houtsmuller, U.M.T., 1975, Specific biological effects of polyunsaturated fatty acids, in: “The Role of Fat in Human Nutrition”, A.J.Vergroesen, ed., Academic Press, London.
Houtsmuller, U.M.T., and van der Beek, A., 1981, Effects of topical application of fatty acids, Prog. Lipid Res. 20: 219.
Jelenko, C., Wheeler, M.L., and Scott, T.H., 1972a, Studies in burns, X. Ethyl linoleate: the water holding lipid of skin, J. Trauma. 12: 968.
Jelenko, C., Wheeler, M.C., and Scott, T.H., 1972b, Studies in burns, XI. Ethyl linoleate: effects on in vivo burn eschar, J. Trauma. 12: 974
Lampe, M.A., Burlingame, A.L., Whitney, J., Williams, M.L., Brown, B. E., Roitman, E., and Elias, P.M., 1983, Human stratum corneum lipids: characterization and regional variations, J. Lipid Res. 24: 120.
Landmann, L., 1984, The epidermal permeability barrier. Comparison between in vivo and in vitro lipid structures Eur. J. Cell. Biol. 33: 258.
Landmann, L., Wertz, P.W., and Downing, D.T., 1984, Acylglucosylceramide causes flattening and stacking of liposomes. An analogy for assembly of the epidermal permeability barrier. Biochim. Biophys. Acta 778: 412.
Madison, K.C., Swartzendruber, D.C., Wertz, P.W., and Downing, D.T., 1988, Lamellar granule extrusion and stratum corneum intercellular lamellae in murine keratinocyte cultures. J. Invest. Dermatol. 90: 110.
Mead, J.F., and Fulco, A.J., 1976, “The Unsaturated and Polyunsaturated Fatty Acids in Health and Disease”, Charles C. Thomas Publisher, Springfiled, U.S.A.
Melton, J.L., Wertz, P.W., Swartzendruber, D.C., and Downing, D.T., 1987, Effects of essential fatty acid deficiency on epidermal O-acylsphingolipids and transepidermal water loss in young pigs, Biochim. Biophys. Acta 921: 191.
Nugteren, D.H., Christ-Hazelhof, E., van der Beek, A., and Houtsmuller, U.M.T., 1985, Metabolism of linoleic acid and other essential fatty acids in the epidermis of the rat, Biochim. Biophys. Acta 834: 429.
Nugteren, D.H., and Kivits, G.A.A., 1987, Conversion of linoleic acid and arachidonic acid by skin epidermal lipoxygenases, Biochim. Biophys. Acta 921: 135.
Prottey, C., 1977, Investigation of functions of essential fatty acids in the skin, Br. J. Dermatol. 97: 29.
Rapport, E.W., Stanley-Samuelson, E., and Dadd, R.H., 1984, Ten generations of drosophila melanogaster reared axenically on a fatty acid-free holidic diet, Arch. Insect Biochem. Physiol. 1: 243.
Scheuplein, R.J., 1976, Permeability of the skin: a review of major concepts and some new developments, J. Invest. Dermatol. 67: 672.
Sinclair, H.M., 1952, Essential fatty acids and their relation to pyridoxine, in: “Lipid Metabolism”, R.T.Williams, ed., The University Press, Cambridge, UK.
Sohal, R.S., Bridges, R.G., and Howes, E.A., 1984, Relationship between lipofuscin granules and polyunsaturated fatty acids in the house fly, Musca Domestica, Mechanism Age. Develop. 25: 355.
Squier, C.A., and Hall, B.K., 1985, The permeability of skin and oral mucosa to water and horseradish peroxidase as related to the tickness of the permeability barrier, J. Invest. Dermatol. 84: 176.
Thomasson, H.J., 1953, Biological standardization of essential fatty acids (a new method), Int. Rev. Vitamin Res. 25: 62
Thomasson, H.J., 1962, Essential fatty acids, Nature 194: 973.
Wertz, P.W., Cho, E.S., and Downing, D.T., 1983, Effect of essential fatty acid deficiency on the epidermal sphingolipids of the rat, Biochim. Biophys. Acta 753: 350.
Wertz, P.W., Cox, P.S., Squier, C.A., and Downing, D.T., 1986, Lipids of epidermis and keratinized and non-keratinized oral epithelia, Comp. Biochem. Physiol. 83B: 529.
Wertz, P.W., and Downing, D.T., 1982, Glycolipids in mammalian epidermis: structure and function in the water barrier, Science 217: 1261.
Wertz, P.W., and Downing, D.T., 1983, Ceramides of pig epidermis. Structure determination, J. Lipid Res. 24: 759.
Wertz, P.W., and Downing, D.T., 1986, Linoleate content of epidermal acylglucosylceramide in newborn, growing and mature mice, Biochim. Biophys. Acta 876: 469.
Wertz, P.W., Donald, C., Swartzendruber, C., Abraham, W., Madison, K.C., and Downing, D.T., 1987, Essential fatty acids and epidermal integrity, Arch. Dermatol. 123: 1381.
Yardley, H.J., and Goldstein, D.J., 1976, Changes in dry weight and projected area of human epidermal cells undergoing keratinization as determined by scanning interference microscopy, Br. J. Dermatol. 95: 621.
Yardley, H.J., and Summerly, R., 1981, Lipid composition and metabolism in normal and diseased epidermis, Pharmac. Ther. 13: 357.
Ziboh, V.A., and Hsia, S.L., 1972, Effects of prostaglandin E2 on rat skin: Inhibition of sterol ester biosynthesis and clearing of scaly lesions in essential fatty acid deficiency, J. Lipid Res. 13: 458.
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Hansen, H.S. (1989). Linoleic Acid and Epidermal Water Barrier. In: Galli, C., Simopoulos, A.P. (eds) Dietary ω3 and ω6 Fatty Acids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2043-3_30
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DOI: https://doi.org/10.1007/978-1-4757-2043-3_30
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