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Immunostimulation in Cancer Patients

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Book cover Biological Response Modifiers in Human Oncology and Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 166))

Abstract

The studies on the cancer immunology and its application to the cancer immunotherapy in humans are attractive subjects for the immunologists and oncologists. However, in order to discuss the immunostimulation and its application to cancer patients, the following should be considered.

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References

  1. Azuma, I., T. Taniyama, F. Hirao and Y. Yamamura. 1974. Antitumor activity of cell wall skeletons and peptidoglycolipids of mycobacteria and related microorganisms in mice and rabbits. Gann 65: 493.

    PubMed  CAS  Google Scholar 

  2. Azuma, I., and Y. Yamamura. 1979. Immunotherapy of cancer with BCG cell-wall skeleton and related materials. Gann Monogr. Cancer Res. 24: 121.

    CAS  Google Scholar 

  3. Cheever, M. A., P. D. Greenberg and A. Fefer. 1981. Specific adoptive therapy of established leukemia with syngeneic lymphocytes sequentially immunized in vivo and in vitro and non-specifically expanded by culture with interleukin 2. J. Immunol. 126: 1318.

    PubMed  CAS  Google Scholar 

  4. Cheever, M. A., P. D. Greenberg, A. Fefer and S. Gillis. 1982. Augmentation of the anti-tumor therapeutic efficacy of longterm cultured T lymphocytes by in vivo administration of purified interleukin. J. Exp. Med. 155: 968.

    Article  PubMed  CAS  Google Scholar 

  5. Ellouz, F., A. Adam, R. Ciorbaru and E. Lederer. 1974. Minimal structure requirements for adjuvant activity of bacterial peptidoglycan derivatives. Biochem. Biophys. Res. Commun. 59: 1317.

    Article  PubMed  CAS  Google Scholar 

  6. Gutterman, J. U., S. Fein, J. Quesada, S. J. Horning, J. L. Levine, R. Alexanian, L. Bernhardt, M. Kramer, H. Speigel, W. Colburn, P. Trown, T. Merigan and Z. Dziewanowska. 1982. Recombinant leukocyte A interferon: Pharmacokinetics, single dose tolerance and biologic effects in cancer patients. Annals of Int. Med. (in press).

    Google Scholar 

  7. Fidler, I. J., S. Sone, W. E. Fogler and J. L. Barnes. 1981. Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide. Proc. Natl. Acad. Sci. USA 78: 1680.

    Article  PubMed  CAS  Google Scholar 

  8. Fidler, I. J., S. Sone, W. E. Fogler, D, Smith, D. G. Braun, L. Tarcsay, R. J. Gisler and A. J. Schroit. 1982. Efficacy of liposomes containing a lipophilic muramyl dipeptide derivative for activating the tumoricidal properties of alveolar macrophages in vivo. J. Biol. Response Modifiers (in press).

    Google Scholar 

  9. Hatzubai, A., D. G. Malone, R. Levy. 1981. The use of a monoclonal anti-idiotype antibody to study the biology of a human B cell lymphoma. J. Icmuunol. 126: 2397.

    CAS  Google Scholar 

  10. Irie, R. F., P. C. Jones, D. L. Morton and N. Sidell. 1981. In vitro production of human antibody to a tumour-associated foetal antigen. Br. J. Cancer 44: 262.

    Article  PubMed  CAS  Google Scholar 

  11. Jones, P. C., L. L. Sze, P. Y. Liu, D. L. Morton and R. F. Irie. 1981. Prolonged survival for melanoma patients with elevated IgM antibody to oncofetal antigen. J. Natl. Cancer Inst. 66: 249.

    PubMed  CAS  Google Scholar 

  12. Kaieda, T., M. Okada, N. Yoshimura, S. Kishimoto, Y. Yamamura and I. Azuma. 1982. A human helper T cell clone secreting both killer helper factor(s) and T cell-replacing factor(s). J. Immunol. 129: 46.

    PubMed  CAS  Google Scholar 

  13. Kotani, S., Y. Watanabe, F. Kinoshita, T. Shimono, I. Morisaki, T. Shiba, S. Kusumoto, Y. Tarumi and K. Ikenaka. 1975. Immunoadjuvant activities of synthetic N-acetylmuramylpeptides or amino acids. Biken J. 18: 105.

    PubMed  CAS  Google Scholar 

  14. Lederer, E. 1982. Immunomodulation by muramyl peptides: Recent developments. Clin. Immunol. Newsletter 3: 83.

    Article  Google Scholar 

  15. Lotze, M.T., E. A. Grimm, A. Mazumder, J. L. Strausser and S. A. Rosenberg. 1981. Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor. Cancer Res. 41: 4420.

    PubMed  CAS  Google Scholar 

  16. Lotze, M. T., B. R. Line, D. J. Mathisen and S. A. Rosenberg. 1980. The in vivo distribution of autologous human and murine lymphoid cells grown in T cell growth factor (TCGFP: Implications for the adoptive immunotherapy of tumors. J. Immunol. 125: 1487.

    PubMed  CAS  Google Scholar 

  17. Magnani, J. L., M. Brockhaus, D. F. Smith, V. Ginsburg, M. Blaszcayk, K. F. Mitchell, Z. Steplewski and H. Koprowski. 1981. A monosialoganglioside is a monoclonal antibody-defined antigen of colon carcinoma. Science 212: 55.

    Article  PubMed  CAS  Google Scholar 

  18. Marx, J. L. 1982. Monoclonal antibodies in cancer. Science 216: 283.

    Article  PubMed  CAS  Google Scholar 

  19. McKneally, M. F., C. Mayer, L. Lininger, H. W. Kausel, J. B. Mcllduff, T. M. Older, E. D. Foster and R. D. Alley. 1981. Four-year follow-up on the Albany experience with intrapleural BCG in lung cancer. J. Thorac. Cardiovas. Surg. 81: 485.

    CAS  Google Scholar 

  20. Miller, R. A. and R. Levy. 1981. Response of cutaneous T cell lymphoma to therapy with hybridoma monoclonal antibody. Lancet 2: 226.

    Article  PubMed  CAS  Google Scholar 

  21. Miller, R. A., D. G. Maloney, J. McKillop, and R. Levy. 1981. In vivo effects of murine hybridoma monoclonal antibody in a patient with T-cell leukemia. Blood 58: 78.

    PubMed  CAS  Google Scholar 

  22. Miller, R. A., D. G. Maloney, R. Warnke, and R. Levy. 1982. Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody. New Eng. J. Med. 306: 517.

    Article  CAS  Google Scholar 

  23. Moller, G. (ed.). 1982. Antibody Carriers of Drugs and Toxins in Tumor Therapy. Immunol. Rev., Vol. 62.

    Google Scholar 

  24. Mountain, C. F. and M. H. Gail. 1981. Surgical adjuvant intra-pleural BCG treatment for Stage I non-small cell lung cancer. J. Thorac. Cardiovasc. Surg. 82: 649.

    Google Scholar 

  25. Ogura, T., M. Namba, Y. Yamamura and I. Azuma. 1979. Immunotherapeutic effect of BCG and Nocardia rubra cell-wall skeletons on syngeneic tumors in rats. In W. D. Terry and Y. Yamamura (eds.) Immunobiology and Immunotherapy of Cancer. Elsevier North/Holland Publishers, New York.

    Google Scholar 

  26. Okada, M., N. Yashimura, T. Kaieda, Y. Yamamura and T. Kishimoto. 1981. Establishment and characterization of human T hybrid cells secreting immunoregulatory molecules. Proc. Natl. Acad. Sci. USA 78: 7717.

    Article  PubMed  CAS  Google Scholar 

  27. Pukel, C. S., K. O. Lloyd, L. R. Travasos, W. G. Dippold, H. F. Oettgen and L. J. Old. 1982. GD3 a prominent ganglioside of human melanoma. J. Exp. Med. 155: 1133.

    Article  PubMed  CAS  Google Scholar 

  28. Ritz, J., J. M. Pesando, J. Notis-McConarty, H. Lazarus and S. Schlossman. 1980. A monoclonal antibody to human acute lymphoblastic leukaemia antigen. Nature 283: 583.

    Article  PubMed  CAS  Google Scholar 

  29. Ritz, J., J. M. Pesando, S. E. Sallan, L. A. Clavell, J. Notis-McConarty, P. Rosenthal and S. F. Schlossman. 1981. Serotherapy of acute lymphoblastic leukemia with monoclonal antibody. Blood 58: 141.

    PubMed  CAS  Google Scholar 

  30. Saiki, I., Y. Tanio, M. Yamawaki, M. Uemiya, S. Kobayashi, T. Fukuda, H. Yukimasa, Y. Yamamura and I. Azuma. 1981. Adjuvant activity of quinonyl-N-acetylmuramyldipeptides in mice and guinea pigs. Infect. Immun. 31: 114.

    PubMed  CAS  Google Scholar 

  31. Sato, H., T. Ochiai, H. Sato, R. Hayashi, K. Watanabe, T. Asano, K. Isono and T. Tanaka. 1982. Result of randomized clinical trial of immunotherapy with Nocardia rubra-CWS. J. Jap. Surg. Soc. (in Japanese) (in press).

    Google Scholar 

  32. Terry, W. D. and S. T. Rosenberg (ed). 1982. Immunotherapy of Human Cancer. Excepta Medica, Amsterdam.

    Google Scholar 

  33. Umezawa, H., T. Aoyagi, H. Suda, M. Hamada and T. Takeuchi. 1976. Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. J. Antibiot. 29: 97.

    Article  PubMed  CAS  Google Scholar 

  34. Yamamura, Y., I. Azuma, K. Sugimura, M. Yamawaki, M. Uemiya, S. Kusumoto, S. Okada and T. Shiba. 1976. Adjuvant activity of 6-O-mycoloyl-N-acetylmuramyl-L-alanyl-D-isoglutamine. Gann 67: 867.

    PubMed  CAS  Google Scholar 

  35. Yamamura, Y., M. Sakatani, T. Ogura and I. Azuma. 1979. Adjuvant immunotherapy of lung cancer with BCG cell wall skeleton (BCG-CWS). Cancer 43: 1314.

    Article  PubMed  CAS  Google Scholar 

  36. Yamamura, Y., T. Ogura, M. Sakatani, F. Hirao, S. Kishimoto, K. Furuse, M. Kawahara, M. Fukuoka, M. Takada, O. Kuwahara and N. Ogawa. 1982a. Randomized controlled study on adjuvant immunotherapy for unresectable lung cancer with Nocardia rubra cell wall skeleton. Gan to Kagakuryoho (in Japanese) (in press).

    Google Scholar 

  37. Yamamura, Y., T. Ogura, M. Sakitani, F. Hirao, S. Kishimoto, K. Furuse, M. Kawahara, M. Fukuoka, M. Takada, O. Kuwahara, H. Ikegami, S. Nakamura and N. Ogawa. 1982b. Clinical effect of Nocardia rubra cell wall skeleton (N-CWS) on lung cancer with malignant pleural effusion. Gan to Kagakuryoho (in Japanese) (in press).

    Google Scholar 

  38. Yamamura, Y., K. Yasumoto, T. Ogura and I. Azuma. 1981. Nocardia rubra cell wall skeleton in the therapy of animal and human cancer. In E. M. Hersh (ed.), Augmenting Agents in Cancer Immunology. Raven Press, New York.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Osaka University, Yamada-oka, Suita, Osaka 565, Japan

    Yuichi Yamamura

  2. Section of Chemistry, Institute of Immunological Science Hokkaido University, Kita-ku, Sapporo 060, Japan

    Ichiro Azuma

Authors
  1. Yuichi Yamamura
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  2. Ichiro Azuma
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Editor information

Editors and Affiliations

  1. University of South Florida, Tampa, Florida, USA

    Thomas Klein , Steven Specter , Herman Friedman  & Andor Szentivanyi , ,  & 

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© 1983 Springer Science+Business Media New York

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Yamamura, Y., Azuma, I. (1983). Immunostimulation in Cancer Patients. In: Klein, T., Specter, S., Friedman, H., Szentivanyi, A. (eds) Biological Response Modifiers in Human Oncology and Immunology. Advances in Experimental Medicine and Biology, vol 166. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1410-4_1

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  • DOI: https://doi.org/10.1007/978-1-4757-1410-4_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1412-8

  • Online ISBN: 978-1-4757-1410-4

  • eBook Packages: Springer Book Archive

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