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Q Fever

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Bacterial Infections of Humans

Q fever is an acute infectious disease caused by Coxiella burnetii. The infection has been reported from all continents of the world and occurs in sporadic and epidemic forms. Human infection is usually acquired by inhalation of the organisms from the tissues of infected domestic animals or their contaminated environment. In its classic form, Q fever has a sudden onset with fever, chills, malaise, weakness, and a severe headache. There is frequently a pneumonitis and, in some cases, signs of hepatic involvement. However, infection with C. Burnetii is usually mild and clinically unrecognized. In contrast to the other rickettsioses, there is no rash, and Proteus agglutinins do not develop. Chloramphenicol and the tetracyclines are highly effective except in cases of subacute endocarditis.

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Authors and Affiliations

  1. Department of Microbiology, University of Maryland School of Medicine, Baltimore, Maryland, 21201, USA

    Paul Fiset

  2. Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, 21201, USA

    Theodore E. Woodward

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  1. Yale University School of Medicine, New Haven, Connecticut, USA

    Alfred S. Evans (John Rodman Paul Professor of Epidemiology) (John Rodman Paul Professor of Epidemiology)

  2. Upstate Medical Center, State University of New York, Syracuse, New York, USA

    Harry A. Feldman

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Fiset, P., Woodward, T.E. (1982). Q Fever. In: Evans, A.S., Feldman, H.A. (eds) Bacterial Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1140-0_24

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