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Escherichia coli Diarrhea

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Abstract

During the 1940s and 1950s, a series of outbreaks of diarrhea in hospital newborn nurseries were reported in which the etiological agent appeared to be Escherichia coli identified by serotype. These strains became known as enteropathogenic E. coli (Epec). Little information has been gathered about these strains in recent years, although it is generally recognized that they are responsible for diarrhea among children under 2 years of age.

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References

  1. Arbuckle, J. B. R., The location of Escherichia coli in the pig intestine, J. Med. Microbiol. 3:333–340 (1970).

    Article  PubMed  CAS  Google Scholar 

  2. Avery, G. B., Villavicencio, O., Lilly, J. R., and Randolph, J. G., Intractable diarrhea in early infancy, Pediatrics 41:712–722 (1968).

    CAS  Google Scholar 

  3. Baker, C. J., Barrett, F. F., and Clark, D. J., Antibiotic susceptibility patterns of enteropathogenic Escherichia coli isolates, South. Med. J. 67:412–414 (1974).

    Article  PubMed  CAS  Google Scholar 

  4. Belnap, W. D., and O’donnell, J. J., Epidemic gastroenteritis due to Escherichia coli 0–111: A review of the literature, with the epidemiology, bacteriology, and clinical findings of a large outbreak, J. Pediatr. 47:178–193 (1955).

    Article  PubMed  CAS  Google Scholar 

  5. Boris, M., Thomason, B. M., Hines, V. D., Montague, T. S., and Sellers, T. F. Jr., A community epidemic of enteropathogenic Escherichia coli 0126 : B16 : Nm gastroenteritis associated with asymptomatic respiratory infection, Pediatrics 33:18–29 (1964).

    PubMed  CAS  Google Scholar 

  6. Bray, J., Isolation of antigenically homogeneous strains of Bact. coli neapolitanum from summer diarrhoea of infants, J. Pathol. Bacteriol. 57:239–247 (1945).

    Article  CAS  Google Scholar 

  7. Byers, P. A., and Dupont, H. L., Pooling method for screening large numbers of Escherichia coli for production of heat-stable enterotoxin, and its application in field studies, J. Clin. Microbiol. 9:541–543 (1979).

    PubMed  CAS  Google Scholar 

  8. Cooper, M. L., Keller, H. M., Walters, E. W., Partin, J. C., and Boye, D. E., Isolation of enteropathogenic Escherichia coli from mothers and newborn infants, Am. J. Dis. Child. 97:255–266 (1959).

    CAS  Google Scholar 

  9. De, S. N., and Chatterje, D. N., An experimental study of action of Vibrio cholerae on the intestinal mucous membrane, J. Pathol. Bacteriol. 66:559–562 (1953).

    Article  PubMed  CAS  Google Scholar 

  10. Dean, A. G., Ching, Y., Nilliams, R. G., and Harden, L. B., Test for Escherichia coli enterotoxin using infant mice: Application in a study of diarrhea in children in Honolulu, J. Infect. Dis. 125:407–411 (1972).

    Article  PubMed  CAS  Google Scholar 

  11. Donta, S. T., Moon, H. W., and Whipp, S. C., Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture, Science 183:334–336 (1974).

    Article  PubMed  CAS  Google Scholar 

  12. Donta, S. T., Sack, D. A., Wallace, R. B., Dupont, H. L., and Sack, R. B., Tissue-culture assay of antibodies to heat-labile Escherichia coli enterotoxins, N. Engl. J. Med. 291:117–121 (1974).

    Article  PubMed  CAS  Google Scholar 

  13. Dupont, H. L., Formal, S. B., Hornick, R. B., Snyder, M. J., Libonati, J. P., Sheahan, D. G., Labrec, E. H., and Kalas, J. P., Pathogenesis of Escherichia coli diarrhea, N. Engl. J. Med. 285:1–9 (1971).

    Article  PubMed  CAS  Google Scholar 

  14. Dupont, H. L., Hornick, R. B., Dawkins, A. T., Snyder, M. J., and Formal, S. B., The response of man to virulent Shigella flexneri 2a, J. Infect. Dis. 119:296–299 (1969).

    Article  PubMed  CAS  Google Scholar 

  15. Dupont, H. L., Olarte, J., Evans, D. G., Pickering, L. K., Galindo, E., and Evans, D. J., Jr., Comparative susceptibility of Latin American and United States students to enteric pathogens, N. Engl. J. Med. 295:1520–1521 (1976).

    Article  PubMed  CAS  Google Scholar 

  16. Dupont, H. L., Sullivan, P., Evans, D. G., Pickering, L. K., Evans, D. J. Jr., Vollet, J. J ., Ericsson, C. D., Ackerman, P. B., and Tjoa, W. S. Prevention of travelers’ diarrhea (emporiatric enteritis) by prophylactic administration of bismuth subsalicylate, J. Am. Med. Assoc. 243:237–241 (1980).

    Article  CAS  Google Scholar 

  17. Drucker, M. M., Poliack, A., Yeivin, R., and Sacks, T. G., Immunofluorescent demonstration of enteropathogenic Escherichia coli in tissues of infants dying with enteritis, Pediatrics 46:855–864 (1970).

    PubMed  CAS  Google Scholar 

  18. Echeverria, P., Blacklow, N. R., and Smith, D. H., Role of heat-labile toxigenic Escherichia coli and reovirus-like agent in diarrhoea in Boston children, Lancet 2:1113–1116 (1975).

    Article  PubMed  CAS  Google Scholar 

  19. Edwards, P. R., and Ewing, W. H., The genus Escherichia, in: Identification of Enterobacteriaceae, 3rd ed., Burgess Publishing, Minneapolis, 1972.

    Google Scholar 

  20. Evans, D. G., Evans, D. J., Jr., and Dupont, H. L., Virulence factors of enterotoxigenic Escherichia coli, J. Infect. Dis. 136:S118-S123 (1977).

    Google Scholar 

  21. Evans, D. G., Evans, D. J., Jr., and Pierce, N. F., Differences in the response of rabbit small intestine to heat-labile and heat-stable enterotoxins of Escherichia coli, Infect. Immun. 7:873–880 (1973).

    CAS  Google Scholar 

  22. Evans, D. J. Jr., and Evans, D. G., Direct serological assay for the heat-labile enterotoxin of Escherichia coli using passive immune hemolysis, Infect. Immun. 16:604–609 (1977).

    PubMed  CAS  Google Scholar 

  23. Evans, D. J., Jr., Evans, D. G., Dupont, H. L., ØRskov, F., and ØRskov, I., Patterns of loss of enterotoxigenicity by Escherichia coli isolated from adults with diarrhea: Suggestive evidence for an interrelationship with serotype, Infect. Immun. 17:105–111 (1977).

    PubMed  CAS  Google Scholar 

  24. Evans, D. J. Jr., Evans, D. G., and Gorbach, S. L., Production of vascular permeability factor by enterotoxigenic Escherichia coli isolated from man, Infect. Immun. 8:725–730 (1973).

    PubMed  CAS  Google Scholar 

  25. Evans, D. J., Jr., Ruiz-Palacios, G., Evans, D. G., Dupont, H. L., Pickering, L. K., and Olarte, J., Humoral immune response to the heat-labile enterotoxin of Escherichia coli in naturally acquired diarrhea and antitoxin determination by passive immune hemolysis, Infect. Immun. 16:781–788 (1977).

    PubMed  Google Scholar 

  26. Farmer, J. J. III., Davis, B. R., Cherry, W. B., Brenner, D. J., Dowell, V. R. Jr., and Balows, A., “Enteropathogenic serotypes” of Escherichia coli which really are not, J. Pediatr. 90:1047–1049 (1977).

    Article  PubMed  CAS  Google Scholar 

  27. Ferguson, W. W., and June, R. C., Experiments on feeding adult volunteers with Escherichia coli 111,B4, a coliform organism associated with infant diarrhea, Am. J. Hyg. 55:155–169 (1952).

    PubMed  CAS  Google Scholar 

  28. Field, M., Graf, L. H., Jr., Laird, W. J., and Smith, P. L., Heat-stable enterotoxin of Escherichia coli: In vitro effects on guanylate cyclase activity, cyclic Gmp concentration, and ion transport in small intestine, Proc. Natl. Acad. Sci. U.S.A. 75:2800–2804 (1978).

    Article  PubMed  CAS  Google Scholar 

  29. Giannella, R. A., Suckling mouse model for detection of heat-stable Escherichia coli enterotoxin: Characteristics of the model, Infect. Immun. 14:95–99 (1976).

    PubMed  CAS  Google Scholar 

  30. Giles, C., Sangster, G., and Smith, J., Epidemic gastro-enteritis of infants in Aberdeen during 1947, Arch. Dis. Child. 24:45–53 (1949).

    Article  PubMed  CAS  Google Scholar 

  31. Goldschmidt, M., and Dupont, H. L., Enteropathogenic Escherichia coli: Lack of correlation of serotype with pathogenicity, J. Infect. Dis. 133:153–156 (1976).

    Article  PubMed  CAS  Google Scholar 

  32. Gorbach, S. L., Banwell, J. G., Chatterjee, B. D., Jacobs, B., and Sack, R. B., Acute undifferentiated human diarrhea in the tropics. I. Alterations in intestinal microflora, J. Clin. Invest. 50:881–889 (1971).

    Article  PubMed  CAS  Google Scholar 

  33. Gorbach, S. L., Kean, B. H., Evans, D. G., Evans, D. J. Jr., and Bessudo, D., Traveler’s diarrhea and toxigenic Escherichia coli, N. Engl. J. Med. 292:933–936 (1975).

    Article  PubMed  CAS  Google Scholar 

  34. Gorbach, S. L., and Khurana, C. M., Toxigenic Escherichia coli: A cause of infantile diarrhea in Chicago, N. Engl. J. Med. 287:791–795 (1972).

    Article  PubMed  CAS  Google Scholar 

  35. Guerrant, R. L., and Brunton, L. L., Characterization of the Chinese hamster ovary cell assay for the enterotoxins of Vibrio cholerae and Escherichia coli and for antitoxin: Differential inhibition by gangliosides, specific antisera, and toxoid, J. Infect. Dis. 135:720–728 (1977).

    Article  PubMed  CAS  Google Scholar 

  36. Guerrant, R. L., Dickens, M. D., Wenzel, R. P., and Kapikian, A. Z., Toxigenic bacterial diarrhea: Outbreak involving multiple bacterial strains, J. Pediatr. 89:885–891 (1976).

    Article  PubMed  CAS  Google Scholar 

  37. Guerrant, R. L., Moore, R. A., Kirschenfeld, P. M. and Sande, M. A., Role of toxigenic and invasive bacteria in acute diarrhea of childhood, N. Engl. J. Med. 293:567–573 (1975).

    Article  PubMed  CAS  Google Scholar 

  38. Gurwith, M., Hinde, D., Gross, R., and Rowe, B., A prospective study of enteropathogenic Escherichia coli in endemic diarrheal disease, J. Infect. Dis. 137:292–297 (1978).

    Article  PubMed  CAS  Google Scholar 

  39. Gurwith, M. J . , and Williams, T. W., Gastroenteritis in children: A two-year review in Manitoba. I. Etiology, J. Infect. Dis. 136:239–247 (1977).

    Article  PubMed  CAS  Google Scholar 

  40. Gurwith, M. J., Wiseman, D. A., and Chow, P., Clinical and laboratory assessment of the pathogenicity of serotyped enterotoxigenic Escherichia coli, J. Infect. Dis. 135:736–743 (1977).

    Google Scholar 

  41. Gyles, C., So, M., and Falkow, S., The enterotoxin plasmids of Escherichia coli, J. Infect. Dis. 130:40–49 (1974).

    CAS  Google Scholar 

  42. Hughes, J. M., Murad, F., Chang, B., and Guerrant, R. L., Role of cyclic Gmp in the action of heat-stable enterotoxin of Escherichia coli, Nature (London) 271:755–756 (1978).

    Article  CAS  Google Scholar 

  43. Ironside, A. G., Tuxford, A. F., and Heyworth, B., A survey of infantile gastroenteritis, Br. Med. J. 3:20–24 (1970).

    Article  PubMed  CAS  Google Scholar 

  44. Saacson, R. E., Fusco, P. C., Brinton, C. C. and Moon, H. W., In vitro adhesion of Escherichia coli to porcine small intestinal epithelial cells: Pili as adhesive factors, Infect. Immun. 21:392–397 (1978).

    Google Scholar 

  45. June, R. C., Ferguson, W. W., and Worfel, M. T., Experiments in feeding adult volunteers with Escherichia coli 55,B5 a coliform organism associated with infant diarrhea, Am. J. Hyg. 57:222–236 (1953).

    PubMed  CAS  Google Scholar 

  46. Jones, G. W., and Rutter, J. M., Role of the K88 antigen in the pathogenesis of neonatal diarrhea caused by E scherichia coli in piglets, I nfect. Immun. 6:918–927 (1972).

    CAS  Google Scholar 

  47. Kapikian, A. Z., Kim, H. W., and Wyatt, R. G., Human reovirus-like agent as the major pathogen associated with “winter” gastroenteritis in hospitalized infants and young children, N. Engl. J. Med. 294:965–972 (1976).

    Article  PubMed  CAS  Google Scholar 

  48. Kaslow, R. A., Taylor, A., Jr., Dweck, H. S., Bobo, R. A., Steele, C. D., and Cassady, G., Jr., Enteropathogenic Escherichia coli infection in a newborn nursery, Am. J. Dis. Child. 128:797–801 (1974).

    PubMed  CAS  Google Scholar 

  49. Kauffmann, F., The serology of the coli group, J. Immunol. 57:71–100 (1947).

    PubMed  CAS  Google Scholar 

  50. Kauffman, F., and Dupont, A. J., Escherichia strains from infantile epidemic gastroenteritis, Acta Pathol. Microbiol. Scand. 27:552–564 (1950).

    Article  Google Scholar 

  51. Kessner, D. M., Shaughnessy, H. J., Googins,J., Rasmussen, C. M., Rose, M. J., Marshall, A. L., Jr., and Elman, S. L., Hall, J. B., and Rosenbloom, P. J., An extensive community outbreak of diarrhea due to enteropathogenic Escherichia coli 011:B4. I. Epidemiologic studies, Am. J. Hyg. 76:27–43 (1962).

    PubMed  CAS  Google Scholar 

  52. Klipstein, F. A., Rowe, B., Engert, R. F., Short, H. B., and Gross, R. J., Enterotoxigenicity of enteropathogenic serotypes of Escherichia coli isolated from infants with epidemic diarrhea, Infect. Immun. 21:171–178 (1978).

    PubMed  CAS  Google Scholar 

  53. Kudoh, Y., Zen-Yoji, H., Matsushita, S., Sakai, S., and Maruyama, T., Outbreaks of acute enteritis due to heat-stable enterotoxin-producing strains of Esche richia coli, Microbiol. Immun. 21:175–178 (1977).

    CAS  Google Scholar 

  54. Levine, M. M., Bergquist, E. J., Nalin, D. R., Waterman, D. H., Hornick, R. B., Young, C. R., Sotman, S., and Rowe, R., Escherichia coli strains that cause diarrhoea but do not produce heat-labile or heat-stable enterotoxins and are non-invasive, Lancet 1:1119–1122 (1978).

    Article  PubMed  CAS  Google Scholar 

  55. Marier, R., Wells, J. G., Swanson, R. C., Callahan, W., and Mehlman, I. J., An outbreak of enteropathogenic Escherichia coli foodborne disease traced to imported French cheese, Lancet 2:1376–1378 (1973).

    Article  Google Scholar 

  56. Mata, L. J., and Urrutia, J. J., Intestinal colonization of breast-fed children in a rural area of low socioeconomic level, Ann. N. Y. Acad. Sci. 176:93–109 (1971).

    Article  Google Scholar 

  57. Merson, M. H., Wells, J. G., Feeley, J. C., Sack, R. B., Creech, W. B., Kapikian, A. Z., Gangarosa, E. J., Morris, G. K., and Sack, R. B., Travelers’ diarrhea in Mexico: A prospective study of physicians and family members attending a congress, N. Engl. J. Med. 294:1299–1305 (1976).

    Article  PubMed  CAS  Google Scholar 

  58. Moon, H. W., Whipp, S. C., Engstrom, G. W., and Baetz, A. L., Response of the rabbit ileal loop to cellfree products from Escherichia coli enteropathogenic for swine, J. Infect. Dis. 121:182–187 (1970).

    Article  PubMed  CAS  Google Scholar 

  59. Neter, E., Enteritis due to enteropathogenic Escherichia coli, J. Pediatr. 55:223–239 (1959).

    Article  PubMed  CAS  Google Scholar 

  60. Neter, E., and Shumway, C. N., E. coli serotype D433: Occurrence in intestinal and respiratory tracts, cultural characteristics, pathogenicity, sensitivity to antibiotics, Proc. Soc. Exp. Biol. Med. 75:504–507 (1950).

    PubMed  CAS  Google Scholar 

  61. Newsome, P. M., Burgess, M. N., and Mullan, N. A., Effect of Escherichia coli heat-stable enterotoxin on cyclic Gmp levels in mouse intestine, Infect. Immun. 22:290–291 (1978).

    PubMed  CAS  Google Scholar 

  62. O’brien, A. D., Thompson, M. R., Cantey, J. R., and Formal, S. B., Production of a Shigella dysenteriae-like toxin by pathogenic Escherichia coli (abstract), Annual Meeting of the American Society of Microbiology, New Orleans, May 8–13, 1977.

    Google Scholar 

  63. Ocklitz, H. W., and Schmidt, E. F., Enteropathogenic Escherichia coli serotypes: Infection of newborn through mother, Br. Med. J. 2:1036–1038 (1957).

    Article  PubMed  CAS  Google Scholar 

  64. Ogawa, H., Nakamura, A., and Sakazaki, R., Pathogenic properties of “enteropathogenic” Escherichia coli from diarrheal children and adults, Jpn. J. Med. Sci. Biol. 21:333–349 (1968).

    PubMed  CAS  Google Scholar 

  65. Pal, S. C., Rao, C. K., Kereselidze, T., Krishnaswami, A. K., Murty, D. K., Pandit, C. G., and Shrivastav, J. B., An extensive community outbreak of enteropathogenic Escherichia coli 086:B7 gastroenteritis, Bull. WHO 41:851–858 (1969).

    PubMed  CAS  Google Scholar 

  66. Pickering, L. K., Dupont, H. L., Evans, D. G., Evans, D. J., Jr., and Olarte, J., Isolation of enteric pathogens from asymptomatic students from the United States and Latin American, J. Infect. Dis. 135:1003–1005 (1977).

    Article  PubMed  CAS  Google Scholar 

  67. Pickering, L. K., Evans, D. J., Jr., Muñiou, O., Dupont, H. L., Coella-Ramirez, P., Vollet, J. J., Conklin, R. H., Olarte, J., and Kohl, S., Prospective study of enteropathogens in children with diarrhea in Houston and Mexico, J. Pediatr. 93:383–388 (1978).

    Article  PubMed  CAS  Google Scholar 

  68. Ramsay, A. M., Acute infective diarrhoea, Br. Med. J. 2:347–350 (1968).

    Article  PubMed  CAS  Google Scholar 

  69. Rogers, K. B., Benson, R. P., Foster, W. P., Jones, L. F., Butler, E. B., and Williams, T. C., Phthalylsulphacetamide and neomycin in the treatment of infantile gastroenteritis, Lancet 2:599–604 (1956).

    Article  Google Scholar 

  70. Rowe, B., Taylor, J., and Bettelheim, K. A., An investigation of travelers’ diarrhoea, Lancet 1:1–5 (1970).

    Article  PubMed  CAS  Google Scholar 

  71. Ruiz-Palacios, G. M., Evans, D. G., Evans, D. J., Jr., and Dupont, H. L., Enzyme linked immunosorbent assay (Elisa) for detection of antibody to heat-labile enterotoxin of Escherichia coli, Abstr.Ann. Meet. Am. Soc. Microbiol. p. 60 (1978) (abstract).

    Google Scholar 

  72. Rutter, J. M., Burrows, M. R., Sellwood, R., and Gibbons, R. A., A genetic basis for resistance to enteric disease caused by E. coli, Nature (London) 257:135–136 (1975).

    Article  CAS  Google Scholar 

  73. Ryder, R. W., Wachsmuth, I. K., Buxton, A. E., Evans, D. G., Dupont, H. L., Mason, E., and Barrett, F. F. Infantile diarrhea produced by heat-stable enterotoxigenic Escherichia coli, N. Engl. J. Med. 295:849–853 (1976).

    CAS  Google Scholar 

  74. Sack, D. A., Kaminsky, D. C., Sack, R. B., Wamola, I. A., ørskov, F., øRskov, I., Slack, R. C. B., Arthur, R. R., and Kapikian, A. Z., Enterotoxigenic Escherichia coli diarrhea of travelers: A prospective study of American Peace Corps volunteers, Johns Hopkins Med. J. 141:64–70 (1977).

    Google Scholar 

  75. Sack, D. A., Mclaughlin, J. C., Sack, R. B., ørskov, F., and Kørskov, I., Enterotoxigenic Escherichia coli isolated from patients at a hospital in Dacca, J. Infect. Dis. 135:275–280 (1977).

    Article  PubMed  CAS  Google Scholar 

  76. Sack, R. B., Gorbach, S. L., Banwell, J. G., Jacobs, B., Chatterjee, B. D., and Mitra, R., Enterotoxigenic Escherichia coli isolated from patients with severe cholera-like disease, J. Infect. Dis. 123:378–385 (1971).

    Article  PubMed  CAS  Google Scholar 

  77. Sack, R. B., Hirschhorn, N., Brownlee, I., Cash, R. A., Woodward, W. E., and Sack, D. A., Enterotoxigenic Escherichia coli-associated diarrheal disease in Apache children, N. Engl. J. Med. 292: 1041–1045 (1975).

    Article  PubMed  CAS  Google Scholar 

  78. Sack, R. B., Jacobs, B., and Mitra, R., Antitoxin responses to infections with enterotoxigenic Escherichia coli, J. Infect. Dis. 129:330–335 (1974).

    Article  PubMed  CAS  Google Scholar 

  79. Sack, R. B., Sack, D. A., Mehlman, I. J., ørskov, F., and ørskov, I., Enterotoxigenic Escherichia coli isolated from food, J. Infect. Dis. 235:313–317 (1977).

    Article  Google Scholar 

  80. Sereny, B., Experimental shigella keratoconjunctivitis: A preliminary report, Acta Microbiol. Acad. Sci. Hung. 2:293–296 (1955).

    PubMed  CAS  Google Scholar 

  81. Smith, H. W., and Gyles, C. L., The relationship between two apparently different enterotoxins produced by enteropathogenic strains of Escherichia coli of porcine origin, J. Med. Microbiol. 3:387–401 (1970).

    Article  PubMed  CAS  Google Scholar 

  82. Smith, H. W., and Halls, S., The transmissible nature of the genetic factor in Escherichia coli that controls enterotoxin production, J. Gen. Microbiol. 52:319–334 (1968).

    Article  Google Scholar 

  83. Smith, H. W., and Linggood, M. A., The transmissible nature of enterotoxin production in a human enteropathogenic strain of Escherichia coli, J. Med. Microbiol. 4:301–305 (1971).

    Article  PubMed  CAS  Google Scholar 

  84. Smith, H. W., and Linggood, M. A., Observation on the pathogenic properties of the K88, Hly and Ent plasmids of Escherichia coli with particular reference to porcine diarrhoea, J. Med. Microbiol. 4:467–485 (1971).

    Article  PubMed  CAS  Google Scholar 

  85. Smith, M. H. D., Newell, K. W., and Sulianti, J., Epidemiology of enteropathogenic Escherichia coli infection in nonhospitalized children, Antimicrob. Agents Chemother., 5:77–83 (1965).

    PubMed  CAS  Google Scholar 

  86. Taylor, J., Infectious infantile enteritis, yesterday and today, Proc. R. Soc. Med. 63:1297–1301 (1970).

    PubMed  CAS  Google Scholar 

  87. Taylor, J., Powell, B. W., and Wright, J., Infantile diarrhea and vomiting: A clinical and bacteriological investigation, Br. Med. J. 2:117–125 (1949).

    Article  PubMed  CAS  Google Scholar 

  88. Taylor, J., Wilkins, M. P., and Payne, J. M., Relations of rabbit gut reaction to enteropathogenic Escherichia coli, Br. J. Exp. Pathol. 42:43–52 (1961).

    PubMed  CAS  Google Scholar 

  89. Thomson, S., Watkins, A. G., and Gray, O. P., Escherichia coli gastroenteritis, Arch. Dis. Child. 31:340–345 (1956).

    Article  PubMed  Google Scholar 

  90. Tjoa, W., Dupont, H. L., Sullivan, P., Pickering, L. K., Holguin, A. H., Olarte, J., Evans, D. G., and Evans, D. J., Jr., Location of food consumption and travelers’ diarrhea, Am. J. Epidemiol. 106:61–66 (1977).

    PubMed  CAS  Google Scholar 

  91. Trabulsi, L. R., and De Toledo, M. R. F., Escherichia coli serogroup 0115 isolated from patients with enteritis: Biochemical characteristics and experimental pathogenicity, Rev. Inst. Med. Trop. Sao Palo 11:358–362 (1969).

    CAS  Google Scholar 

  92. Tulloch, E. F., Jr., Ryan, K. J., Formal, S. B., and Franklin, F. A., Invasive enteropathogenic Escherichia coli dysentery: An outbreak in 28 adults, Ann. Intern. Med. 79:13–17 (1973).

    PubMed  Google Scholar 

  93. Wheeler, W. E., Spread and control of Escherichia coli diarrheal disease, Ann. N. Y. Acad. Sci. 66:112–117 (1969).

    Article  Google Scholar 

  94. Williams, P. H., Sedgwick, M. I., Evans, N., Turner, P. J., George, R. H., and Mcneish, A. S., Adherence of an enteropathogenic strain of Escherichia coli to human intestinal mucosa is mediated by a colicinogenic conjugative plasmid, Infect. Immun. 22:392–402 (1978).

    Google Scholar 

  95. Yow, M. D., Melnick, J. L., Blattner,R. J., Stephenson, W. B., Robison, N. W. and Burkhardt, M. A., The association of viruses and bacteria with infantile diarrhea, Am. J. Epidemiol. 92:33–39 (1970).

    PubMed  CAS  Google Scholar 

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    Article  PubMed  CAS  Google Scholar 

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    Article  CAS  Google Scholar 

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DuPont, H.L. (1982). Escherichia coli Diarrhea. In: Evans, A.S., Feldman, H.A. (eds) Bacterial Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1140-0_12

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