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Abstract

During the last decade many in vitro systems have been developed as short-term tests for chemical, viral and physical carcinogenesis. A complete battery of such tests should include bacterial and mammalian mutagenesis, chromosome tests, DNA repair and cell transformation. These tests have been developed on the assumption that the oncogenic event is based on a genotoxic mechanism, the endpoint of which is detectable in a qualitative or quantitative way in each system.

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© 1983 Springer Science+Business Media New York

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Cortesi, E. (1983). In Vitro Studies on Chemical Carcinogenesis in BALB/c 3T3 Cells. In: Castellani, A. (eds) The Use of Human Cells for the Evaluation of Risk from Physical and Chemical Agents. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1117-2_46

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  • DOI: https://doi.org/10.1007/978-1-4757-1117-2_46

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1119-6

  • Online ISBN: 978-1-4757-1117-2

  • eBook Packages: Springer Book Archive

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