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Lipoxin Syntheses by Arachidonate 12- and 5-Lipoxygenases Purified from Porcine Leukocytes

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Lipoxins

Abstract

Recently, we were successful in the purification of 12-lipoxygenase1 and 5-lipoxygenase2 from porcine leukocytes by immunoaffinity chromatography using their monoclonal antibodies which were raised with the crude enzyme preparations as antigen3, 4. In this chapter the lipoxin biosynthesis will be discussed as catalytic properties of these purified lipoxygenases.

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References

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Author information

Authors and Affiliations

  1. Department of Biochemistry, Tokushima University School of Medicine, Tokushima 770, Japan

    Shozo Yamamoto, Natsuo Ueda & Chieko Yokoyama

  2. Merck Frosst Canada, Inc., Pointe Claire-Dorval, Quebec, H9R 4P8, Canada

    Brian J. Fitzsimmons & Joshua Rokach

  3. Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, 37232, USA

    John A. Oates & Alan R. Brash

Authors
  1. Shozo Yamamoto
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  2. Natsuo Ueda
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  3. Chieko Yokoyama
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  4. Brian J. Fitzsimmons
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  5. Joshua Rokach
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  6. John A. Oates
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  7. Alan R. Brash
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, New York Medical College, 10595, Valhalla, New York, USA

    Patrick Y.-K. Wong

  2. Hematology Division, Brigham and Women’s Hospital and Harvard Medical School, 02115, Boston, Massachusetts, USA

    Charles N. Serhan

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© 1988 Springer Science+Business Media New York

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Yamamoto, S. et al. (1988). Lipoxin Syntheses by Arachidonate 12- and 5-Lipoxygenases Purified from Porcine Leukocytes. In: Wong, P.YK., Serhan, C.N. (eds) Lipoxins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0937-7_2

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  • DOI: https://doi.org/10.1007/978-1-4757-0937-7_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0939-1

  • Online ISBN: 978-1-4757-0937-7

  • eBook Packages: Springer Book Archive

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