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The Use of Monoclonal Antibodies in Studies of the Structural Proteins of Togaviruses and Flaviviruses

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The Togaviridae and Flaviviridae

Part of the book series: The Viruses ((VIRS))

Abstract

Since the initial reports of the isolation and characterization of monoclonal antibodies (MAb’s) specific for alphaviruses (Roehrig et al., 1980) and flaviviruses (Dittmar et al., 1980), the arbovirus community has experienced a virtual explosion in the research applications of MAb’s to the antigenic analysis of these important human and veterinary pathogens. This research, reviewed in the following pages, has revolutionized our understanding of both the molecular and the clinical immunology of togaviruses and flaviviruses.

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Authors and Affiliations

  1. Division of Vector-Borne Viral Diseases, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Fort Collins, Colorado, 80522, USA

    John T. Roehrig

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  1. John T. Roehrig
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Editors and Affiliations

  1. Department of Microbiology and Immunology, Washington University School of Medicine, 63110, St. Louis, Missouri, USA

    Sondra Schlesinger  & Milton J. Schlesinger  & 

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© 1986 Plenum Press, New York

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Roehrig, J.T. (1986). The Use of Monoclonal Antibodies in Studies of the Structural Proteins of Togaviruses and Flaviviruses. In: Schlesinger, S., Schlesinger, M.J. (eds) The Togaviridae and Flaviviridae. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0785-4_9

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  • DOI: https://doi.org/10.1007/978-1-4757-0785-4_9

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