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Contemporary Topics in Molecular Immunology pp 365–413Cite as

Molecular Events in Lymphocyte Activation: Role of Nonhistone Chromosomal Proteins in Regulating Gene Expression

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Part of the book series: Contemporary Topics in Molecular Immunology ((CTI))

Abstract

The resting small lymphocyte and the plasma cell have the same genetic complement, but phenotypically they are at opposite ends of the spectrum of metabolic activity. Both the transformation from B lymphocyte to antibody producer and the transformation from T lymphocyte to effector cell (producing one of a multitude of factors of varying specificities and functions) are initiated by a binding event at the cell surface, which is followed approximately 24 hr later by the onset of DNA synthesis and the morphological changes we term blastogenesis. In the ensuing differentiation to plasma cell or T effector cell, memory cells are also created that can respond more rapidly to a second encounter with the same antigen.

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References

  • Adkinson, N. F., Jr., Rosenberg, S. A., and Terry, W. D., 1974, J. Immunol. 112:1426. Allen, D., Auger, J., and Crumpton, M. J., 1972, Nature (London) New Biol. 236:23. Allfrey, V. G., Littau, V. C., and Mirsky, A. E., 1963, Proc. Natl. Acad. Sci. U.S.A. 49:414. Allfrey, V. G., Kam, J., Johnson, E. M., and Vidali, G., 1974, in: Control of Proliferation in

    Google Scholar 

  • Animal Cells (B. Clarkson and R. Baserga, eds.), p. 681, Cold Spring Harbor Laboratory, New York.

    Google Scholar 

  • Allfrey, V. G., Inoue, A., Karn, J., Johnson, E. M., Good, R. A., and Hadden, J. W., 1975, in: The structure and Function of Chromatin, Ciba Found. Symp., Vol. 28, p. 199, Elsevier, Amsterdam.

    Google Scholar 

  • Allwood, G., Asherson, G. L., Davey, M. J., and Goodford, P. J., 1971, Immunology 21: 509.

    PubMed  CAS  Google Scholar 

  • Andersson, J., and Melchers, F., 1973 Proc. Natl. Acad. Sci. U.S.A. 70:416.

    Google Scholar 

  • Andersson, J., Sjoberg, O., and Möller, G., 1972 Transplant. Rev. 11:131.

    Google Scholar 

  • Atkinson, J. P., Wedner, H. J., and Parker, C. W., 1975, J. Immunol. 115:1023. Bach, F., and Hirschhorn, K., 1963, Exp. Cell Res. 32: 592.

    Google Scholar 

  • Barker, K. L., 1971 Biochemistry 10:284.

    Google Scholar 

  • Baserga, R., and Stein, G., 1971, Fed. Proc. Fed. Am. Soc. Exp. Biol. 30:1752. Basham, T. Y., and Waxdai, M. J., 1975, J. Immunol. 114: 5827.

    Google Scholar 

  • Baxter, J. D., Rousseau, G. G., Higgins, S. J., and Tomkins, G. M., 1973, in: The Biochemistry of Gene Expression in Higher Organisms (J. R. Pollak and J. W. Lee, eds.), p. 206, Australian and New Zealand Book Co., Sydney.

    Google Scholar 

  • Bekhor, I., Kung, G. M., and Bonner, J., 1969,J. Mol. Biol. 39:351.

    Google Scholar 

  • Benjamin, W., and Gellhorn, A., 1968 Proc. Natl. Acad. Sci. U.S.A. 59: 262.

    Google Scholar 

  • Berridge, M. J., 1975, in: Advances in Cyclic Nucleotides, Vol. 6 (P. Greengard and G. A. Robison, eds.), p. 1, Raven Press, New York.

    Google Scholar 

  • Blankenship, J., and Bresnick, E., 1974 Biochim. Biophys. Acta 340:218.

    Google Scholar 

  • Blitstein-Willinger, E., Schulz, G., and Diamantstein, T., 1976, Immunology 30:529. Boffa, L. C., Vidali, G., and Allfrey, V. G., 1976, Exp. Cell Res 98: 396.

    Google Scholar 

  • Bottoms, G. D., and Jungmann, R. A., 1973 Proc. Soc. Exp. Biol. Med. 144:83.

    Google Scholar 

  • Boume, H. R., Lichtenstein, L. M., Melmon, K. L., Henney, C. S., Weinstein, Y., and Shearer, G. M., 1974, Science 184: 19.

    Article  Google Scholar 

  • Brostrom, C. O., Hunkeler, F. L. and Krebs, E. G., 1971, J. Biol. Chem. 246:1961. Buell, D. N., and Fahey, J. L., 1969, Science 164: 1524.

    Google Scholar 

  • Burleson, D. G., and Sage, H. J., 1976 J. Immunol. 116:696.

    Google Scholar 

  • Busch, G I Yeoman, L. C., Taylor, C. W., and Busch, H., 1974 Physiol. Chem. Phys. 6:1. Busch, H., 1965 Histones and Other Nuclear ProteinsAcademic Press, New York.

    Google Scholar 

  • Byus, C. V., Klimpel, G. R., Lucas, D. O., and Russell, R. H., 1977 Nature (London) 268:63.

    Google Scholar 

  • Calkins, C. E., Ozer, H., and Waksman, B. H., 1975, Cell. Immunol. 18: 187.

    Google Scholar 

  • Chambon, P., Gissinger, F., Mandel, J. L., Kedinger, G., Gniazdowski, M., and Meihloc, M., 1970, Cold Spring Harbor Symp. Quant. Biol. 35: 693.

    Article  CAS  Google Scholar 

  • Chiu, J.-F., Craddock, C., Getz, S., and Hnilica, L. S., 1973, FEBS Lett. 33:247. Chiu, J.-F., Wang, S., Fujitani, H., and Hnilica, L. S., 1975, Biochemistry 14:4552. Coffey, R. G., Hadden, E. M., and Hadden, J. W., 1977,J. Immunol. 119:1387. Cone, R. E., 1976, J. Immunol 116: 847.

    Google Scholar 

  • Cone, R. E., 1977, in: The Lymphocyte: Structure and Function (J. J. Marchalonis, ed.), p. 565, Marcel Dekker, New York.

    Google Scholar 

  • Cooper, H. L., 1973, in: Drugs and the Cell Cycle (A. M. Zimmerman, G. M. Padille, and I. L. Cameron, eds.), p. 137, Academic Press, New York.

    Google Scholar 

  • Cooper, H. L., and Rubin, A. D., 1965 Blood 25:1014.

    Google Scholar 

  • Couch, R. M., and Anderson, K. M., 1973 Biochem. Biophys. Res. Commun. 50:478. Coutinho, A., Möller, G., Andersson, J., and Bullock, W. W., 1973 Eur. J. Immunol. 3:299. Cross, M. E., and Ord, M. G., 1971 Biochem. J. 124:241.

    Google Scholar 

  • Cuatrecasas, P., 1975, in: Advances in Cyclic Nucleotide Research, Voi. 5, (G. I. Drummond, P. Greengard, and G. A. Robison, eds.), p. 79, Raven Press, New York.

    Google Scholar 

  • Cullen, S. E., David, C. S., Schreffler, D. C., and Nathanson, S. G., 1974, Proc. Natl. Acad. Sci. U.S.A. 71: 648.

    Article  PubMed  CAS  Google Scholar 

  • Decker, J. M., and Marchalonis, J. J., 1977a Biochem. Biophys. Res. Commun. 74:584 Decker, J. M., and Marchalonis, J. J., 1977b, in The Immune System: Genetics and Regulation (E. Sercarz, L. Herzenberg, and C. F. Fox, eds.), p. 719, Academic Press, New York.

    Google Scholar 

  • Decker, J. M., Wan, G. W., and Marchalonis, J. J., 1977, Biochem. Biophys. Res. Commun. 74: 1536.

    Google Scholar 

  • Defer, N., Kitzis, A., Kruh, J., Brahms, S., and Brahms, J., 1977, Nucleic Acids Research 4: 2293.

    Article  PubMed  CAS  Google Scholar 

  • DeRubertis, F. R., Zenser, T. V., Adler, W. H., and Hudson, T., 1974, J. Immunol. 113:151. DiSabato, G., Chen, D., and Erickson, J. W., 1975 Cell. Immunol. 17:495.

    Google Scholar 

  • Douvas, A. S., Harrington, C. A., and Bonner, J., 1975, Proc. Natl. Acad. Sci. U.S.A. 72: 3902.

    Article  PubMed  CAS  Google Scholar 

  • Edelman, G. M., 1976 Science 192:218.

    Google Scholar 

  • Elgin, S. C. R., and Weintraub, H., 1975 Annu. Rev. Biochem. 44:725.

    Google Scholar 

  • Faragó, A., Antoni, F., and Fâbiân, F., 1974, Biochim. Biophys. Acta 370:459. Felsenfeld, G., 1978, Nature 271: 115.

    Google Scholar 

  • Ferber, E., and Resch, K., 1973 Biochim. Biophys. Acta 296:335.

    Google Scholar 

  • Ferber, E., and Resch, K., 1977, in: The Lymphocyte: Structure and Function (J. J. Marchalonis, ed.), p. 593, Marcel Dekker, New York.

    Google Scholar 

  • Ferber, E.. dePasquale, G. G., and Resch, K., 1975, Biochim. Biophys. Acta 398:364. Ferguson, R. M., Schmidtke, J. R., and Simmons, R. L., 1976, J. Immunol. 116:627. Fisher, D. B., and Mueller, G. C., 1968, Proc. Natl. Acad. Sci. U.S.A. 60:1396. Fisher, D. B., and Mueller, G. C., 1971, Biochim. Biophys. Acta 248: 434.

    Google Scholar 

  • Freedman, M. H., Raff, M. C., and Gomperts, B., 1975,Nature (London) 225:378. Frenster, J. H., 1965, Nature (London) 206: 680.

    Google Scholar 

  • Frenster, J. H., Allfrey, V. G., and Mirsky, A. E., 1963, Proc. Natl. Acad. Sci. U.S.A. 50: 1026.

    Google Scholar 

  • Garel, A., and Axel, R., 1976 Proc. Natl. Acad. Sci. U.S.A. 73:3966.

    Google Scholar 

  • Garrard, W. T., and Bonner, J., 1974 J. Biol. Chem. 249:5570.

    Google Scholar 

  • Gerner, E. W., and Humphrey, R. M., 1973, Biochim. Biophys. Acta 231:117. Gery, I., and Waksman, B. H., 1972, J. Exp. Med. 136: 143.

    Google Scholar 

  • Gilmour, R. S., and Paul, J., 1969,J. Mol. Biol. 40:137.

    Google Scholar 

  • Gilmour, R. S., and Paul, J., 1975, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 19, Academic Press, New York.

    Google Scholar 

  • Gilmour, R. S., Windass, J. D., Affara, N., and Paul, J., 1975, J. Cell. Physiol. 85:449. Gmelig-Meyling, F., UytdelHaag, A. G. C. M., and Ballieux, R. E., 1977, Cell. Immunol. 33: 156.

    Google Scholar 

  • Goldberg, N. D., Haddox, M. K., Dunham, E., Lopez, C., and Hadden, J. W., 1974, in: Control of Proliferation in Animal Cells (B. Clarkson and R. Baserga, eds.), p. 609, Cold Spring Harbor Laboratory, New York.

    Google Scholar 

  • Goldberg, N. D., Haddox, M. K., Nicol, S. E., Glass, D. B., Sanford, C. H., Kuehl, F. A., Jr.,and Estensen, R., 1975, in: Advances in Cyclic Nucleotides Research,Vol. 5 (G. I.

    Google Scholar 

  • Drummond, P. Greengard, and G. A. Robison, eds.), p. 307, Raven Press, New York. Goodwin, G. H., Nicolas, R. H., and Johns, E. W., 1975a, Biochim. Biophys. Acta 405:280. Goodwin, G. H., Shooter, K. V., and Johns, E. W., 1975b, Eur. J. Biochem. 54:427. Gorski, J., and Gannon, F., 1976, Annu. Rev. Physiol. 38: 425.

    Google Scholar 

  • Greaves, M 1977 Nature (London) 265:681.

    Google Scholar 

  • Greaves, M, and Janossy, G., 1972 Transplant. Rev. 11:87.

    Google Scholar 

  • Greene, W. C., and Parker, C. W., 1975, Biochem. Biophys Re Commun. 65:456. Greene, W. C., Parker, C. M., and Parker, C. W., 1976, Cell. Immunol. 25: 74.

    Google Scholar 

  • Greengard, P., 1976 Nature (London) 260:101.

    Google Scholar 

  • Hadden, J. W., 1975 Ann. N. Y. Acad. Sci. 256:352.

    Google Scholar 

  • Hadden, J. W., Hadden, E. M., Haddox, M. K., and Goldberg, N. D., 1972, Proc. NatL Acad. Sci. U.S.A. 69: 3024.

    Article  PubMed  CAS  Google Scholar 

  • Hadden, J. W., Hadden, E. M., Sadlik, J. R., and Coffey, R. G., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 1717.

    Google Scholar 

  • Haddox, M. K., Furcht, L. T., Gentry, S. R., Moser, M. E., Stephenson, J. H., and Goldberg, N. D., 1976, Nature (London) 262: 146.

    Article  CAS  Google Scholar 

  • Hancock, R., 1969, J. Mol. Biol. 40:457.

    Google Scholar 

  • Hausen, P., Stein, H., and Peters, H., 1969 Eur. J. Biochem. 9:542.

    Google Scholar 

  • Hayden, G. A., Crowley, G. M., and Jamieson, G. A., 1970, J. Biol. Chem. 245:5827. Henkart, P. A., and Fisher, R I., 1975, J. Immunol. 114: 710.

    Google Scholar 

  • Henney, C. S., and Bubbers, J. E., 1973, J. Immunol 111: 85.

    PubMed  CAS  Google Scholar 

  • Hirschhorn, R., Troll, W., Brittinger, G., and Weissmann, G., 1969, Nature (London) 222: 1247.

    Article  CAS  Google Scholar 

  • How, K., and Wang, T. Y., 1969 Arch. Biochem. Biophys. 133:238.

    Google Scholar 

  • Huang, R. C., and Bonner, J., 1962, Proc. Natl. Acad. Sci. U.S.A. 48: 1216.

    Article  PubMed  CAS  Google Scholar 

  • Huang, R. C., and Huang, P. C., 1969 J. Mol. Biol. 39: 365.

    Google Scholar 

  • Hunt, S. M., and Marchalonis, J. J., 1974, Biochem. Biophys. Res. Commun. 61:1227. Inoue, M., Kishimoto, A., Takai, Y., Nishizuka, Y., 1977, J. Biol. Chem. 252:7610. Javaherian, K., Liu, L. F., and Wang, J. C., 1978, Science 199: 1345.

    Google Scholar 

  • Jazwinski, S. M., Wang, J. L., and Edelman, G. M., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 2231.

    Google Scholar 

  • Jensen, E. V., and DeSombre, E. R., 1973 Science 182:126.

    Google Scholar 

  • Jensen, E. V., Mumata, M., Brechex, P. I., and DeSombre, E. R., 1971, in The Biochemistry of Steroid Hormone Action (R. M. S. Smellie, ed.), p. 133, Academic Press, New York. Johns, E. W., Goodwin, G. H., Walker, J. M., and Sanders, C., 1975, in: The Structure and Function of Chromatin, CIBA Found. Symp.,Vol. 28, p. 95, Elsevier, Amsterdam. Johnson, E. M., 1977, in: Advances in Cyclic Nucleotides,Vol. 8 (P. Greengard and G. A.Robison, eds.), p. 267, Raven Press, New York.

    Google Scholar 

  • Johnson, E. M., and Allfrey, V. G., 1972 Arch. Biochem. Biophys. 152:786.

    Google Scholar 

  • Johnson, E. M., and Hadden, J. W., 1975 Science 187:1198.

    Google Scholar 

  • Johnson, E. M., Kam, J., and Allfrey, V. G., 1974, J. Biol. Chem. 249: 4990.

    PubMed  CAS  Google Scholar 

  • Johnson, E. M., Hadden J. W., Inoue, A., and Allfrey, V. G., 1975a, Biochemistry 14:3873. Johnson, E. M., Inoue, A., Crouse, L. J., Allfrey, V. G., and Hadden, J. W., 1975b, Biochem. Biophys. Res. Commun. 65: 714.

    CAS  Google Scholar 

  • Johnson, L. D., and Hadden, J. W., 1977 Nucleic Acids Research 4:4007.

    Google Scholar 

  • Jones, G., 1973 Cell. Immunol. 9:393.

    Google Scholar 

  • Jungmann, R. A., and Schweppe, J. S., 1972, J. Biol. Chem. 247:5535.

    Google Scholar 

  • Jungmann, R. A., Lee, S., and DeAngelo, A. B., 1975, in: Advances in Cyclic Nucleotide Research, Vol. 5 (G. I. Drummond, P. Greengard, and G. A. Robison, eds.), p. 281, Raven Press, New York.

    Google Scholar 

  • Kamiyama, M., and Dastugue, B., 1971, Biochem. Biophys. Res. Commun. 44:29. Kamiyama, M., and Wang, T. Y., 1971, Biochim. Biophys. Acta 228: 563.

    CAS  Google Scholar 

  • Kam, J., Johnson, E. M., Vidali, G., and Allfrey, V. G., 1974, J. Biol. Chem. 249:667. Karn, J., Vidali, G., Boffa, L. C., and Allfrey, V. G., 1977, J. Biol. Chem. 252:7307. Katagiri, T., Terao, T., and Osawa, T., 1976, J. Biochem. 79: 849.

    Google Scholar 

  • Kay, J. E., 1972 Exp. Cell Res 71:245.

    Google Scholar 

  • Kay, J. E., and Cooke, A., 1971, FEBS Lett. 16: 9.

    Article  PubMed  CAS  Google Scholar 

  • Kay, J. E., and Cooper, H. L., 1969 Biochim. Biophys. Acta 186:62.

    Google Scholar 

  • Keller, R., 1975 Cell. Immunol. 17:542.

    Google Scholar 

  • Kemp, B. E., Froscio, M., Rogers, A., and Murray, A. W., 1975, Biochem. J. 145:241. Kishimoto, A., Takai, Y., and Nishizuka, Y., 1977, J. Biol. Chem. 252: 7449.

    Google Scholar 

  • Kishimoto, T., Miyake, T., Nishizawa, Y., Watanabe, T., and Yamamura, Y., 1975, J. ImmunoL 115: 1179.

    PubMed  CAS  Google Scholar 

  • Kishimoto, T., Nishizawa, Y., Kikutani, H., and Yamamura, Y., 1977, J. Immunol. 118: 2027.

    PubMed  CAS  Google Scholar 

  • Kleinsmith, L. J., 1973, J. Biol. Chem. 248: 5648.

    CAS  Google Scholar 

  • Kleinsmith, L. J., 1975a, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 45, Academic Press, New York.

    Google Scholar 

  • Kleinsmith, L. J., 1975bJ. Cell. Physiol. 85:459.

    Google Scholar 

  • Kleinsmith, L. J., and Allfrey, V. G., 1969, Biochim. Biophys. Acta 175:123. Kleinsmith, L. J., Allfrey, V. G., and Mirsky, A. E., 1966, Science 154: 780.

    Google Scholar 

  • Kleinsmith, L. J., Heidema, J., and Carroll, A., 1970 Nature (London) 226:1025. Kleinsmith, L. J., Stein, J., and Stein, G., 1975, in Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 59,Academic Press, New York.

    Google Scholar 

  • Kleinsmith, L. J., Stein, J., and Stein, G., 1976, Proc. Natl. Acad. Sci. USA 73:1174. Kornberg, R. D., 1974, Science 184: 868.

    Google Scholar 

  • Kostraba, N. C., and Wang, T. Y., 1972 Biochim. Biophys. Acta 262:169.

    Google Scholar 

  • Krishnaraj, R., and Talwar, G. P., 1973, J. Immunol. 111: 1010.

    Google Scholar 

  • Kruh, J., Courtois, Y., Dastugue, B., Defer, N., Gibson, K., Kamiyama, M., and Tichonicky, L., 1975, in: Regulation of Growth and Differentiated Function in Eukaryote Cells (G. P. Talwar, ed.), p. 139, Raven Press, New York.

    Google Scholar 

  • Lauf, P. K., 1975 Biochim. Biophys. Acta 415:173.

    Google Scholar 

  • Lazo, J. S., Prasad, K. N., and Ruddon, R. W., 1976 Exp. Cell Res. 100:41.

    Google Scholar 

  • Levy, R., and Rosenberg, S. A., 1972, J. Immunol. 108: 1073.

    Google Scholar 

  • Levy, R., and Rosenberg, S. A., 1973 Cell. Immunol. 7:92.

    Google Scholar 

  • Levy, R., Levy, S., Rosenberg, S. A., and Simpson, R. T., 1973 Biochemistry 12: 224. Liew, C. C., and Chan, P. K., 1976 Proc. Natl. Acad. Sci. U.S.A. 73:3458.

    Google Scholar 

  • Ling, N. R., and Kay, J. E., 1975 Lymphocyte StimulationNorth-Holland, Amsterdam. Loeb, J. E., and Creuzet, C., 1970 Bull. Soc. Chim. Biol. 52:1007.

    Google Scholar 

  • Lucas, D. O., Shohet, S. B., and Merler, E., 1971, J. Immunol. 106: 768.

    Google Scholar 

  • Lucas, Z. J., 1967 Science 156:1237.

    Google Scholar 

  • Luckasen, J. R., White, J. G., and Kersey, J. H., 1974, Proc. Natl. Acad. Sci. U.S.A. 71:5088.

    Google Scholar 

  • Lyle, L. R., and Parker, C. W., 1974 Biochemistry 13:5415.

    Google Scholar 

  • MacGillvray, A. J., Carroll, D., and Paul, J., 1971, FEBS Lett. 13: 204.

    Article  Google Scholar 

  • MacManus, J. P., Whitfield, J. F., Boynton, A. L., and Rixon, R. H., 1975, in: Advances in Cyclic Nucleotide Research, Vol. 5 (G. I. Drummond, P. Greengard, and G. A. Robison, eds.), p. 719, Raven Press, New York.

    Google Scholar 

  • Maino, V. C., Green, N. M., and Crumpton, M. J., 1974, Nature (London) 251:324. Makman, M. H., 1971, Proc. Natl. Acad. Sci. U.S.A. 68: 885.

    Google Scholar 

  • Marchalonis, J. J., 1976, in: Contemporary Topics in Molecular Immunology (H. N. Eisen and R. A. Reisfeld, eds.), Vol. 5, p. 125, Plenum Press, New York.

    Google Scholar 

  • McClain, D. A., and Edelman, G. M., 1976, J. Exp. Med. 144:1494.

    Google Scholar 

  • Melcher, U., and Uhr, J. W., 1977 Biochemistry 16:145.

    Google Scholar 

  • Melchers, F., and Andersson, J., 1973 Transplant. Rev. 14:76.

    Google Scholar 

  • Mendelsohn, J., Skinner, A., and Kornfeld, S., 1971, J. Clin. Invest. 50: 818.

    Google Scholar 

  • Michell, R. H., 1975 Biochim. Biophys Acta 415:81.

    Google Scholar 

  • Milner, S. M., 1977 Nature (London) 268:441.

    Google Scholar 

  • Niedermeir, W., Schrohenloher, R. E., and Hurst, M., 1972, J. Immunol. 108:346. Nilsson, S. F., and Waxdal, M. J., 1976, Biochemistry 15: 2698.

    Google Scholar 

  • Nimmo, H. G. and Cohen, P., 1977, in: Advances in Cyclic Nucleotide Research, Vol. 8, (P. Greengard and G. A. Robison, eds.), p. 145, Raven Press, New York.

    Google Scholar 

  • Nishizawa, Y., Kishimoto, T., Kikutani, H., and Yamamura, Y., 1977, J. Exp. Med. 146: 653.

    Article  PubMed  CAS  Google Scholar 

  • Novogrodsky, H., 1972, Biochim. Biphys. Acta 266: 343.

    Article  CAS  Google Scholar 

  • Olson, M. O. J., and Busch, H., 1974, in: The Cell Nucleus, Vol. 3 (H. Busch, ed.), p. 211, Academic Press, New York.

    Google Scholar 

  • Olson, M. O. J., Starbuck, W. C., and Busch, H., 1974, in: The Molecular Biology of Cancer (H. Busch, ed.), p. 309, Academic Press, New York.

    Google Scholar 

  • O’Malley, B. W., and Means, A. R., 1974, in: The Cell Nucleus, Vol. 3 (H. Busch, ed.), p. 379, Academic Press, New York.

    Google Scholar 

  • O’Malley, B. W., Spelsberg, T. C., Schrader, W. T., Chytil, F., and Steggles, A. W., 1972, Nature (London) 235: 141.

    Article  Google Scholar 

  • O’Malley, B. W., Woo, S. L. C., Harris, S. E., Rosen, J. M., and Means, A. R., 1975, J. Cell. Physiol. 85: 343.

    Article  Google Scholar 

  • Oppenheim, J. J., and Rosenstreich, D. L., 1976, Prog. Allergy 20: 65.

    Article  PubMed  CAS  Google Scholar 

  • Oppenheimer, J. H., Schwartz, H. L., Surks, M. I., Koerner, D., and Dillmann, W. H., 1976, in: Recent Progress in Hormone Research, Vol. 32 (R. O. Greep, ed.), p. 529, Academic Press, New York.

    Google Scholar 

  • Ozato, K., Adler, W. H., and Ebert, J. D., 1975, Cell. Immunol. 17: 532.

    Article  PubMed  CAS  Google Scholar 

  • Painter, R. G., and White, A., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 837.

    Article  PubMed  CAS  Google Scholar 

  • Parker, C. W., 1974a, Biochem. Biophys. Res. Commun. 61: 1180.

    Google Scholar 

  • Parker, C. W., 1974b, in: Cyclic AMP, Cell Growth and the Immune Response (W. Braun, L. Lichtenstein, and C. Parker, eds.), p. 35, Springer-Verlag, New York.

    Google Scholar 

  • Parker, C. W., Smith, J. W., and Steiner, A. L., 1971, Int. Arch. Allergy Appl. Immunol. 41: 40.

    Article  PubMed  CAS  Google Scholar 

  • Parkhouse, R. M. E., Janossy, G., and Greaves, M. F., 1972, Nature (London) New BioL 235: 21.

    Article  CAS  Google Scholar 

  • Paul, J., and Gilmour, R. S., 1968, J. Mol Biol. 34: 305.

    Article  PubMed  CAS  Google Scholar 

  • Peters, J. H., and Hausen, P., 1971a, Eur. J. Biochem. 19: 502.

    Article  PubMed  CAS  Google Scholar 

  • Peters, J. H., and Hausen, P., 1971b, Eur. J. Biochem. 19: 509.

    Article  PubMed  CAS  Google Scholar 

  • Peterson, J. L., and McConkey, E. H., 1976, J. Biol. Chem. 251: 548.

    PubMed  CAS  Google Scholar 

  • Platz, R. D., Grimes, S. R., Hard, G., Meistrich, M. L., and Hnilica, L. S., 1975, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 67, Academic Press, New York.

    Google Scholar 

  • Pogo, B. G. T., 1972, J. Cell Biol. 53: 635.

    Article  PubMed  CAS  Google Scholar 

  • Pogo, B. G. T., Allfrey, V. G., and Minsky, A. E., 1966, Proc. Natl. Acad. Sci. U.S.A. 55:805.

    Google Scholar 

  • Putnam, F. W., Florent, G., Paul, C., Shinoda, T., and Shimizu, A., 1973, Science 182:287. Quastel, M. R., and Kaplan, J. G., 1970, Exp. Cell Res. 63: 230.

    Google Scholar 

  • Rasmussen, H., Jensen, P., Lake, W., Friedmann, N., and Goodman, D. B. P., 1975, in: Advances in Cyclic Nucleotide Research, VoL 5 (G. L Drummond, P. Greengard, and G. A. Robison, eds.), p. 375, Raven Press, New York.

    Google Scholar 

  • Ravid, A., and Novogrodsky, A., 1976, Exp. Cell Res. 97: 1.

    Article  PubMed  CAS  Google Scholar 

  • Resch, K., Gelfand, E. W., Hanson, K., and Ferber, E., 1972, Eur. J. Immunol. 2:598. Rickwood, D., Riches, P. G., and MacGillivray, A. J., 1973, Biochim. Biophys. Acta 299: 162.

    Google Scholar 

  • Robison, G. A., Butcher, R. W., and Sutherland, E. W., 1971, Cyclic AMP, Academic Press, New York.

    Google Scholar 

  • Rosenberg, S. A., and Levy, R., 1972, J. Immunol. 108: 1105.

    Google Scholar 

  • Rosentreich, D. L., Farrar, J. J., and Dougherty, S., 1976, J. Immunol 116:131. Rovera, G., and Baserga, R., 1971,J. Cell. Physiol. 77: 201.

    Google Scholar 

  • Rubin, A. D., and Cooper, H. L., 1965 Proc. Natl. Acad. Sci. U.S.A. 54:469.

    Google Scholar 

  • Samuels, H. H., and Tsai, J. S., 1973 Proc. Natl. Acad. Sci. U.S.A. 70:3488.

    Google Scholar 

  • Scheid, M. P., Hoffman, M. K., Komuro, K., Hämmerling, U., Abbot, J., Boyse, E. A., Cohen, G. H., Hooper, J. A., Schulof, R. S., and Goldstein, A. L., 1973, J. Exp. Med. 138: 1027.

    Google Scholar 

  • Schmidtke, J. R., and Hatfield, S., 1976 J. Immunol. 116:357.

    Google Scholar 

  • Schmidtke, J. R., and Najarian, J. S., 1975, J. Immunol. 114: 742.

    CAS  Google Scholar 

  • Schmidt-Ullrich, R., Wallach, D. F. H., and Hendricks, J., 1976, Biochim. Biophys. Acta 443: 587.

    Article  PubMed  CAS  Google Scholar 

  • Schreiner, G. F., and Unanue, E. R., 1976 Adv. Immunol. 24:37.

    Google Scholar 

  • Schumm, D. E., Morris, H. P., and Webb, T. E., 1974 Eur. J. Cancer 10:107.

    Google Scholar 

  • Segrest, J. P., and Feldmann, R. J., 1974 J. Mol. Biol. 87:853.

    Google Scholar 

  • Sekeris, C. E., and Schmid, W., 1973, in: The Biochemistry of Gene Expression in Higher Organisms (J. K. Pollak and J. W. Lee, eds.), p. 225, Australian and New Zealand Book Co., Sydney.

    Google Scholar 

  • Sell, S., 1974 Cell. Immunol. 12:119.

    Google Scholar 

  • Sell, S., and Gell, P. G. H., 1965 J. Exp. Med 122:423.

    Google Scholar 

  • Sell, S., and Sheppard, H. W., Jr., 1974 Exp. Cell Res. 84:153.

    Google Scholar 

  • Sell, S., Rowe, D. S., and Gell, P. G. H., 1965 J. Exp. Med. 122:823.

    Google Scholar 

  • Sharma, O. K., and Loeb, L. A., 1973, Biochim. Biophys. Res. Commun. 50:172. Shea, M., and Kleinsmith, L. J., 1973, Biochem. Biophys. Res. Commun. 50:473. Shek, P. N., Chou, C.-T., Dubinski, S., and Cinader, B., 1974, Int. Arch. Allergy Appl.Immunol. 46: 753.

    Google Scholar 

  • Shelton, K. R., and Allfrey, V. G. 1970 Nature (London) 228:132.

    Google Scholar 

  • Sheppard, H. W., Jr., Redelman, D., and Sell, S., 1976 Cell. Immunol. 24:34.

    Google Scholar 

  • Siebert, G., Ord, M. G., and Stocken, L. A., 1971 Biochem. J. 122:721.

    Google Scholar 

  • Silver, L. M., and Elgin, S. C. R., 1976 Proc. Natl. Acad. Sci. U.S.A. 73:423.

    Google Scholar 

  • Smith, J. W., Steiner, A. L., Newberry, W. M., Jr., and Parker, C. W., 1971, J. Clin. Invest. 50. 432.

    Article  PubMed  CAS  Google Scholar 

  • Snary, D., Goodfellow, P., Hayman, M. J., Bodmer, W. F., and Crumpton, M. J., 1970, Nature (London) 247: 457.

    Article  Google Scholar 

  • Sorg, C., 1975 Eur. J. Biochem. 55:423.

    Google Scholar 

  • Sorg, C., and Bloom, B. R., 1973 J. Exp. Med. 137:148.

    Google Scholar 

  • Spelsberg, T., and Hnilica, L., 1970, Biochem. J. 120: 435.

    PubMed  CAS  Google Scholar 

  • Spelsberg, T. C., Hnilica, L. S., and Ansevin, A. T. 1971 Biochim. Biophys. Acta 228:550. Spelsberg, T. C., Webster, R., and Pikier, G. M., 1975, in Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 153, Academic Press, New York.

    Google Scholar 

  • Spivak, J. L., 1976 Blood 47:581.

    Google Scholar 

  • Stein, G., and Baserga, R., 1970,J. Biol. Chem. 245:6097.

    Google Scholar 

  • Stein, G. S., and Borun, T. W., 1972, J. Cell Biol. 52:292.

    Google Scholar 

  • Stein, G. S., Spelsberg, T. C., and Kleinsmith, L. J., 1974 Science 183:817.

    Google Scholar 

  • Stein, G., Park, W., Thrall, C., Mans, R., and Stein, J., 1975a, Nature (London) 257:764. Stein, G., Stein, J., Thrall, C., and Park, W., 1975b, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 1, Academic Press, New York.

    Google Scholar 

  • Symons, D. B. A., Lay, C. A., and MacDonald, A. N., 1977, Int. Arch. Allergy App. Immunol. 54: 67.

    Article  CAS  Google Scholar 

  • Takai, Y., Kishimoto, A., Inoue, M., and Nishizuka, Y., 1977, J. Biol. Chem. 252:7603. Takeda, M., Yamamura, H., and Ohga, Y., 1971, Biochem. Biophys. Res. Commun. 42:103. Tashiro, T., and Kurokawa, M., 1975, Eur. J. Biochem. 60: 569.

    Google Scholar 

  • Teng, C. S., Teng, C. T., and Allfrey, V. G., 1971, J. Biol. Chem. 246: 3597.

    PubMed  CAS  Google Scholar 

  • Toyoshima, S., Iwata, M., and Osawa, T., 1976 Nature (London) 264:447.

    Google Scholar 

  • Tsuboi, A., and Baserga, R., 1972, J. Cell. Physiol. 80:107.

    Google Scholar 

  • Turkington, R. W., and Majumder, G. C., 1975 J. Cell. Physiol. 85:495 van den Broek, H. W. J., Noodén, L. D., Sevall, J. S., and Bonner, J., 1973, Biochemistry 12:229.

    Google Scholar 

  • Vidali, G., Boffa, L. C., Littau, V. C., Allfrey, K. M., and Allfrey, V. G., 1973, J. Biol. Chem. 248: 4065.

    PubMed  CAS  Google Scholar 

  • Vidali, G., Boffa, L. C., and Allfrey, V. G., 1977 Cell 12:409.

    Google Scholar 

  • Walsh, F. S., and Crumpton, M. J., 1977, Nature (London) 269: 307.

    Article  CAS  Google Scholar 

  • Wang, J. L., Gunther, G. R., and Edelman, G. M., 1975 J. Cell Biol. 66:128.

    Google Scholar 

  • Wang, T. Y., 1967 J. Biol. Chem. 242:1220.

    Google Scholar 

  • Wang, T. Y., and Kostraba, N. C., 1975, in: Chromosomal Proteins and Their Role in the Regulation of Gene Expression (G. S. Stein and L. J. Kleinsmith, eds.), p. 35, Academic Press, New York.

    Google Scholar 

  • Warner, N. L., 1974 Adv. Immunol. 19:67.

    Google Scholar 

  • Warr, G. W., and Marchalonis, J. J., 1976 Immunochemistry 13:753.

    Google Scholar 

  • Watson, J., 1974, in: The Immune System: Genes, Receptors, Signals, (E. E. Sercarz, A. R. Williamson, and C. F. Fox, eds.), p. 511, Academic Press, New York.

    Google Scholar 

  • Watson, J., Epstein, R., and Cohn, M., 1973 Nature (London) 246:405.

    Google Scholar 

  • Weber, Th.H., Skoog, V. T., Mattsson, A., and Lindahl Kiessling, K., 1974, Exp. Cell Res. 85:351

    Google Scholar 

  • Wedner, H. J., and Parker, C. W., 1975, Biochem. Biophys. Res. Commun. 62:808. Wedner, H. J., and Parker, C. W., 1976, Prog. Allergy 20: 195.

    Google Scholar 

  • Wedner, H. J., Danker, R., and Parker, C. W., 1975 J. Immunol. 115:1682.

    Google Scholar 

  • Weintraub, H., and Groudine, M., 1976, Science 193: 848.

    Google Scholar 

  • Weisenthal, L. M. and Ruddon, R W., 1972, Cancer Res. 32: 1009.

    PubMed  CAS  Google Scholar 

  • Weisenthal, L. M., and Ruddon, R. W., 1973 Cancer Res. 33:2923.

    Google Scholar 

  • Whitney, R. B., and Sutherland, R. M., 1972 Cell. Immunol. 5:137.

    Google Scholar 

  • Yamamoto, I., and Webb, D. R., 1975 Proc. Natl. Acad. Sci. U.S.A. 72:2320.

    Google Scholar 

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  1. Cancer Biology Program, NCI Frederick Cancer Research Center, Frederick, Maryland, 21701, USA

    Janet M. Decker & John J. Marchalonis

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  1. Janet M. Decker
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  1. Department of Molecular Immunology, Scripps Clinic and Research Foundation, La Jolla, California, USA

    Ralph A. Reisfeld

  2. Department of Biochemistry, East Tennessee State University, Johnson City, Tennessee, USA

    F. P. Inman

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Decker, J.M., Marchalonis, J.J. (1978). Molecular Events in Lymphocyte Activation: Role of Nonhistone Chromosomal Proteins in Regulating Gene Expression. In: Reisfeld, R.A., Inman, F.P. (eds) Contemporary Topics in Molecular Immunology. Contemporary Topics in Molecular Immunology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0779-3_11

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