Abstract
The quantitative roles of insulin and glucagon in the regulation of hepatic ketogenesis are still not defined adequately. Glucagon added in vitro has been reported by certain workers to stimulate ketogenesis in perfused livers from normal-fed rats (Heimberg, Weinstein, and Kohout, 1969; Weinstein, Klausner, and Heimberg, 1973). However, other workers did not observe a ketogenic effect of the hormone under similar conditions (McGarry and Foster, 1978; McGarry, Wright, and Foster, 1975).
This work was supported, in part, by grants from New Mexico Heart Association, Pharmaceutical Manufacturers Association, and the New Mexico Medical Foundation.
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Woodside, W.F. (1979). Influence of Insulin and Glucagon on Ketogenesis by Isolated Rat Hepatocytes. In: Klachko, D.M., Anderson, R.R., Heimberg, M. (eds) Hormones and Energy Metabolism. Advances in Experimental Medicine and Biology, vol 111. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0734-2_5
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