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Monoaminergic Systems in the Human Limbic Brain

  • Chapter
Limbic Mechanisms

Abstract

There exist several reports in the literature on the distribution of serotonin (5-HT), dopamine (DA) and noradrenaline (NA) in the limbic system of laboratory animals (Paasonen et al, 1957; Brownstein et al, 1974; Saavedra et al, 1974). In addition to these reports, which are based on chemical analyses of the brain monoamines in question, there exists a wealth of pertinent information obtained by means of the histofluorescence technique for the visualization of monoamines in brain tissue (Dahlström & Fuxe, 1964; Fuxe, 1965; Lindvall & Bjorklund, 1974). However, to our knowledge, there exist no systematic biochemical studies of the monoamine levels in limbic areas of the human brain. This report deals with the distribution of 5-HT, DA and NA in limbic areas of the neurologically normal human brain, thus providing a suitable framework for future studies on the behaviour of these monoamines in the limbic brain of patients with neurological and/or psychiatric illnesses.

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Authors
  1. I. J. Farley
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  2. K. S. Price
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  3. O. Hornykiewicz
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Editor information

Editors and Affiliations

  1. University of Toronto, Canada

    Kenneth E. Livingston  & Oleh Hornykiewicz  & 

  2. The Wellesley Hospital, 160 Wellesley StEast, Toronto, Canada

    Kenneth E. Livingston

  3. Institute of Biochemical Pharmacology, University of Vienna, Austria

    Oleh Hornykiewicz

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© 1978 Springer Science+Business Media New York

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Farley, I.J., Price, K.S., Hornykiewicz, O. (1978). Monoaminergic Systems in the Human Limbic Brain. In: Livingston, K.E., Hornykiewicz, O. (eds) Limbic Mechanisms. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0716-8_12

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  • DOI: https://doi.org/10.1007/978-1-4757-0716-8_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0718-2

  • Online ISBN: 978-1-4757-0716-8

  • eBook Packages: Springer Book Archive

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