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Radiotherapy as salvage or consolidation therapy in advanced epithelial ovarian cancer

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Ovarian Cancer 3

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Abstract

Survival results after treatment of advanced epithelial ovarian cancer are disappointing. While cisplatin alone or in combination produces response rates of approximately 60–80% in advanced disease, the initial optimism that overall cure rates in ovarian cancer would be substantially improved has not been fulfilled. The duration of relapse-free time has been increased over that achieved with single agent alkylating agents, but only 5–10% more patients are long term disease-free survivors [1]. Overall cure rates in advanced disease remain about 20–30% [2–4]. One strategy that has been generally pursued in improving treatment outcomes in solid tumours has been to attempt to combine effective therapies sequentially or concurrently, particularly if their toxicities are non-overlapping.

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Authors
  1. G. M. Thomas
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Editors and Affiliations

  1. Department of Obstetrics and Gynaecology, Northern General Hospital, Sheffield University, Sheffield, UK

    Frank Sharp  & Tony Blackett  & 

  2. The Samaritan Hospital for Women, St Mary’s Hospital Medical School, London, UK

    Peter Mason

  3. Division of Gynecologic Oncology, UCLA School of Medicine, Los Angeles, USA

    Jonathan Berek

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© 1995 Chapman & Hall

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Thomas, G.M. (1995). Radiotherapy as salvage or consolidation therapy in advanced epithelial ovarian cancer. In: Sharp, F., Mason, P., Blackett, T., Berek, J. (eds) Ovarian Cancer 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0136-4_27

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  • DOI: https://doi.org/10.1007/978-1-4757-0136-4_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0138-8

  • Online ISBN: 978-1-4757-0136-4

  • eBook Packages: Springer Book Archive

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