Abstract
Avian infectious bronchitis virus strain Kagoshima-34 isolated from the kidneys of a chicken that died of nephrosis/nephritis lost its nephropathogenicity during intratracheal passage in SPF chickens. The resultant virus acquired stronger respirotropism but reduced tropism for kidneys. On the other hand strain Tottori-2 isolated from the trachea of a chicken suffering from severe respiratory disease did not lose its respirotropism after serial intravenous passage in SPF chickens.
The serological properties of the passaged virus were investigated by virus neutralisation test. The antibody titres of both strains of virus fluctuated with progressive passage. The serological properties of the virus isolated from respiratory organs were not necessarily the same as those of the isolates made from the kidneys.
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References
D.J. Alexander and R.E. Gough. Isolation of avian infectious bronchitis virus from experimentally infected chickens. Res. Vet. Sci., 23:34-4–(1977).
R.C. Jones. Nephrosis in laying chickens caused by Massachusetts-type infectious bronchitis virus. Vet. Rec., 95:319 (1974.).
K. Otsuki, Y. Tagawa and M. Tsubokura. Antigenic variation of avian infectious bronchitis virus during replication in BHK-21 cells. Arch. Virol., 73:75 (1982).
K. Otsuki, K. Noro, H. Yamamoto and M. Tsubokura. Studies on avian infectious bronchitis virus (IBV). II. Replication of IBV in several cultured cells. Arch. Virol., 60:115 (1979).
K. Otsuki, T. Nakamura, N. Kubota, Y. Kawaoka and M. Tsubokura. Comparison of two strains of avian infectious bronchitis virus for their interferon induction, viral growth and development of virus -neutralizing antibody in experimentally infected chickens. Vet. Microbiol., 15:31 (1987).
F. Taguchi, S.G. Siddel, H. Wege and V. Meulen. Characterization of a variant virus selected in rat brain after infection by Coronavirus mouse hepatitis virus JHM. J. Virol., 54:4–29 (1985).
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© 1990 Plenum Press, New York
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Otsuki, K., Matsuo, K., Maeda, N., Sanekata, T., Tsubokura, M. (1990). Selection of Variants of Avian Infectious Bronchitis Virus Showing Tropism for Different Organs. In: Cavanagh, D., Brown, T.D.K. (eds) Coronaviruses and their Diseases. Advances in Experimental Medicine and Biology, vol 276. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5823-7_52
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DOI: https://doi.org/10.1007/978-1-4684-5823-7_52
Publisher Name: Springer, Boston, MA
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