Abstract
The M protein of coronaviruses is an integral membrane protein, the general properties of which have been described elsewhere in this volume. The protein is ascribed a pivotal role in the budding process of these viruses. Its restriction to internal membranes suggests it to be a major factor in determining the intracellular site of virion assembly. In addition, M is thought to effect budding through the interaction of its cytoplasmic tail with the nucleocapsid.
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Keywords
- Mutant Protein
- Infectious Bronchitis Virus
- Recombinant Vaccinia Virus
- Feline Infectious Peritonitis
- Indirect Immunofluorescence Microscopy
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© 1990 Plenum Press, New York
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Rottier, P.J.M., Locker, J.K., Horzinek, M.C., Spaan, W.J.M. (1990). Expression of MHV-A59 M Glycoprotein: Effects of Deletions on Membrane Integration and Intracellular Transport. In: Cavanagh, D., Brown, T.D.K. (eds) Coronaviruses and their Diseases. Advances in Experimental Medicine and Biology, vol 276. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5823-7_19
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DOI: https://doi.org/10.1007/978-1-4684-5823-7_19
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