Abstract
Much evidence points to the possibility that the rate limiting step in acetylcholine synthesis is bound to a mass action effect of its substrates: choline and acetyl-CoA 1–3. The availability of choline and acetyl-CoA thus is of crucial importance for the synthesis of the neurotransmitter.
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Massarelli, R., Mandel, P. (1976). On the Uptake Mechanism of Choline in Nerve Cell Cultures. In: Levi, G., Battistin, L., Lajtha, A. (eds) Transport Phenomena in the Nervous System. Advances in Experimental Medicine and Biology, vol 69. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-3264-0_15
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DOI: https://doi.org/10.1007/978-1-4684-3264-0_15
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