Abstract
During the first week after parturition, rat pups were removed and returned to a mother-present nest, were removed and returned to a mother-absent nest, were separated from their mothers by removal of the mothers, or were undisturbed. In adulthood, when repeatedly injected with a dose of D-amphetamine which induces progressively higher levels of stereotypy (2.5 mg/kg), only subjects which had been removed and returned to a mother-present nest in infancy showed a retarded rate of increase in stereotypy.
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References
Bell, R.W., Nitschke, W., Bell, N.J. and Zackman, T.A. (1974). Early experience, ultrasonic vocalization, and maternal responsiveness in rats. Dev. Psyohobiol. 7 ,235–243.
Bennett, D.S. and Giarman, N.J. (1965). Schedule of appearance of 5-hydroxytryptamine (serotonin) and associated enzymes in the developing rat brain. J. Neurochem. 12 ,911–918.
Davis, J.M. Catecholamines and psychosis. In Cateoholamines and Behavior (Friedhoff, A.J., Ed.) pp. 135–154. Plemun Press, New York.
Denenberg, V.H. (1964). Critical periods, stimulus input and emo tional reactivity: A theory of infantile stimulation. Psychol. Rev. 71 ,335–351.
Denenberg, V.H. and Zarrow, M.S. (1971). Effects of handling in infancy upon adult behavior and adrenocortical activity: Suggestions for a neuroendocrine mechanism. In The Developmental of Self-Regulatory Mechanisms (Walcher, D.N. and Peters, D.L., Eds.) pp. 40–74. Academic Press, New York.
Iversen, S.D. and Iversen, L.L. (1975). Behavioral Pharmacology pp. 269–292. Oxford University Press, New York and Oxford.
Kirk, R.E. (1968). Experimental Design: Procedures for the Behavioral Sciences. Brooks/Cole Publishing Co., Belmont.
Levine, S. and Mullins, R. (1968). Hormones in infancy. In Early Experience and Behavior (Newton, G. and Levine, S., Eds.) pp. 168–197. Thomas, Springfield.
Loizou, L.A. (1972). The postnatal ontogeny of monoamine-containing neurones in the central nervous system of the albino rat. Brain Res. 40 ,395–418.
Randrup, A., Munkvad, K., Fog, R. and Ayhan, I.H. (1975). Catechola- mines in activation, stereotypy and level of mood. In Catechol- amines and Behavior (Friedhoff, A.J., Ed.) pp. 89–107. Plenum Press, New York.
Schi¢rring, E. (1971). Amphetamine induced selective stimulation of certain behaviour items with concurrent inhibition of others in an open-field test with rats. Behavior 34 ,1–17.
Schreiber, H., Bell, R., Conely, L., Kufner, M., Palet, J. and Wright, L. (in press). Diminished reaction to a novel stimulus during amphetamine withdrawal in rats. Pharmac. Bioehem. Behav.
Schreiber, H.L., Bell, R.W., Kufner, M. and Villescas, R. (in press). Maternal behavior: A determinant of amphetamine toxicity in rats. Psychopharmacology.
Segal, D.S. and Mandell, A.J. (1974). Long-term administration of d-amphetamine: Progressive augmentation of motor activity and stereotypy. Pharmac. Bioehem. Behav. 2 ,249–255.
Smotherman, W.P., Bell, R.W., Starzec, J., Elias, J. and Zachman, T.A. (1974). Maternal response to infant vocalizations and olfactory cues in rats and mice. Behav. Biol. 12 ,55–66.
Stone, E.A. (1975). Stress and Catecholamines. In Catecholamines and Behavior v. 2 ,(Friedhoff, A.J., Ed.) pp. 31–72. Plenum Press, New York.
Villescas, R., Bell, R.W., Wright, L. and Kufner, M. (in press). Effect of handling on maternal behavior following return of pups to the nest. Ðev. Psychobiol.
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© 1977 Plenum Press, New York
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Bell, R.W., Schreiber, H.L. (1977). Maternally Determined Susceptibility to D-Amphetamine-Induced Stereotypy in Rats. In: Messiha, F.S., Kenny, A.D. (eds) Parkinson’s Disease. Advances in Experimental Medicine and Biology, vol 90. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-2511-6_19
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DOI: https://doi.org/10.1007/978-1-4684-2511-6_19
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