Skip to main content

The Effects of Gonadal Hormones on Water and Electrolyte Metabolism in the Human

  • Chapter
Metabolic Effects of Gonadal Hormones and Contraceptive Steroids

Abstract

For many years, physicians have had the impression that the administration of gonadal hormones could under certain circumstances cause fluid retention in the human subject. The impression was strengthened by experiments in the late nineteen-thirties showing that gonadal hormones could cause marked fluid retention in animals (1,2). These experiments led in turn to the proposal that gonadal hormones were responsible for the cyclical fluid retention frequently seen in women before the menses (3).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Thorn, G.W. and Harrop, G.A.: Sodium retaining effect of sex hormones. Science 86: 40–41 (1937).

    Article  PubMed  CAS  Google Scholar 

  2. Thorn, G.W. and Engel, L.L.: Effect of sex hormones on renal excretion of electrolytes. J. Exper. Med. 68: 299–312 (1938).

    Article  CAS  Google Scholar 

  3. Thorn, G.W. and Emerson, K., Jr.: Role of gonadal and adrenal cortical hormones in production of edema. Ann. Int. Med. 14:757–769 (1940).

    CAS  Google Scholar 

  4. Knowlton, K., Kenyon, A.T., Sandiford, I., Lotwin, G. and Fricker, R.: Comparative study of metabolic effects of estradiol benzoate and testosterone propionate in man. J. Clin. Endocr. 2:671–684 (1942).

    Article  CAS  Google Scholar 

  5. Borun, E.R. and Geiger, E.: Interrelationships of some metabolic effects of testosterone propionate in normal males during restricted sodium intake. J. Clin. Invest. 35:1109–1118 (1956).

    Article  PubMed  CAS  Google Scholar 

  6. Landau, R.L. and Lugibuhl, K.: The catabolic and natriuretic effects of progesterone in man. Recent Progr. Hormone Res.17:249–292 (1961).

    CAS  Google Scholar 

  7. Laidlaw, J.C., Ruse, J.L. and Gomall, A.G.: The influence of estrogen and progesterone on aldosterone excretion. J. Clin. Endocr. 22:161–171 (1962).

    Article  PubMed  CAS  Google Scholar 

  8. George, J.M., Saucier, G. and Bartter, F.C.: Is there a potent naturally occurring sodium-losing steroid hormone? J. Clin. Endocr. 25: 621–627 (1965).

    Article  PubMed  CAS  Google Scholar 

  9. Preedy, J.R.K, and Aitken, E.H.: Effect of estrogen on water and electrolyte metabolism; normal. J. Clin. Invest. 35: 423–429 (1956).

    Article  PubMed  CAS  Google Scholar 

  10. Preedy, J.R.K, and Aitken, E.H.: Effect of estrogen on water and electrolyte metabolism; hepatic disease. J. Clin. Invest. 35:430–442 (1956).

    Article  PubMed  CAS  Google Scholar 

  11. Preedy, J.R.K, and Aitken, E.H.: Effect of estrogen on water and electrolyte metabolism; ca?:diac and renal disease. J. Clin. Invest.35: 443–451 (1956).

    Article  PubMed  CAS  Google Scholar 

  12. Katz, F.H. and Kappas, A.: The effects of estradiol and estriol on plasma levels of Cortisol and thyroid hormone-binding globulins and on aldosterone and Cortisol secretion rates. J. Clin. Invest. 46:1768–1776 (1967).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1969 Plenum Press, New York

About this chapter

Cite this chapter

Preedy, J.R.K. (1969). The Effects of Gonadal Hormones on Water and Electrolyte Metabolism in the Human. In: Salhanick, H.A., Kipnis, D.M., Wiele, R.L.V. (eds) Metabolic Effects of Gonadal Hormones and Contraceptive Steroids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1782-1_30

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-1782-1_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1784-5

  • Online ISBN: 978-1-4684-1782-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics